Identification of potential driver genes in human liver carcinoma by genomewide screening

scientific article published on 14 April 2009

Identification of potential driver genes in human liver carcinoma by genomewide screening is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1158/0008-5472.CAN-09-0164
P932PMC publication ID2750086
P698PubMed publication ID19366792
P5875ResearchGate publication ID24277938

P2093author name stringSnorri S Thorgeirsson
Eun Sung Park
Ju-Seog Lee
Yoon Jun Kim
Hyun Goo Woo
Yun-Han Lee
Tsuyoshi Ishikawa
P2860cites workHeat shock factor 1 is a powerful multifaceted modifier of carcinogenesisQ24655006
Defining the role of mTOR in cancerQ28235431
An integrated data analysis approach to characterize genes highly expressed in hepatocellular carcinomaQ28237169
The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and diseaseQ29547614
Open source clustering softwareQ29547702
Coexpression analysis of human genes across many microarray data setsQ30936126
A tumor progression model for hepatocellular carcinoma: bioinformatic analysis of genomic data.Q31065517
Microarray analysis reveals a major direct role of DNA copy number alteration in the transcriptional program of human breast tumorsQ34190883
Whole genome scanning identifies genotypes associated with recurrence and metastasis in prostate tumorsQ34320113
Genetic regulators of large-scale transcriptional signatures in cancerQ34537800
Phase II study of Erlotinib (OSI-774) in patients with advanced hepatocellular cancerQ34560933
Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets.Q34710149
OncoDB.HCC: an integrated oncogenomic database of hepatocellular carcinoma revealed aberrant cancer target genes and lociQ35179204
Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugsQ36494138
Focal gains of VEGFA and molecular classification of hepatocellular carcinomaQ36984575
Pivotal role of mTOR signaling in hepatocellular carcinomaQ37183244
The antidiabetic drug metformin exerts an antitumoral effect in vitro and in vivo through a decrease of cyclin D1 level.Q40021818
Systemic treatment with the antidiabetic drug metformin selectively impairs p53-deficient tumor cell growthQ40105523
Human scribble accumulates in colorectal neoplasia in association with an altered distribution of beta-cateninQ40131614
Mammalian target of rapamycin activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growthQ40136518
Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemiaQ40158237
Regional copy number-independent deregulation of transcription in cancerQ40209266
Metformin is an AMP kinase-dependent growth inhibitor for breast cancer cellsQ40216291
Gene expression signature-based chemical genomic prediction identifies a novel class of HSP90 pathway modulatorsQ40225712
Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistanceQ40225720
Chromosome alterations in human hepatocellular carcinomas correlate with aetiology and histological grade--results of an explorative CGH meta-analysisQ41886998
Genome-wide molecular profiles of HCV-induced dysplasia and hepatocellular carcinomaQ41918713
Multiple regions within 8q24 independently affect risk for prostate cancerQ42038345
Heat shock transcription factor (HSF1) plays a critical role in cell migration via maintaining MAP kinase signalingQ42498513
Gene expression-based recurrence prediction of hepatitis B virus-related human hepatocellular carcinomaQ44902374
mTOR and P70 S6 kinase expression in primary liver neoplasmsQ45205087
Predicting hepatitis B virus-positive metastatic hepatocellular carcinomas using gene expression profiling and supervised machine learningQ45728735
Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancerQ46520772
A novel prognostic subtype of human hepatocellular carcinoma derived from hepatic progenitor cellsQ50115050
Systems biology and combination therapy in the quest for clinical efficacy.Q51934858
Classification and prediction of survival in hepatocellular carcinoma by gene expression profiling.Q52087746
High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patientsQ57274902
Molecular pathogenesis of human hepatocellular carcinomaQ74543031
Phase 2 study of erlotinib in patients with unresectable hepatocellular carcinomaQ80595806
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectliver carcinomaQ18557387
P304page(s)4059-4066
P577publication date2009-04-14
P1433published inCancer ResearchQ326097
P1476titleIdentification of potential driver genes in human liver carcinoma by genomewide screening
P478volume69