Functional dissection of the mouse tyrosinase locus control region identifies a new putative boundary activity

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Functional dissection of the mouse tyrosinase locus control region identifies a new putative boundary activity is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/GKG793
P8608Fatcat IDrelease_jtntcx73pfazvfcy2b5rnplkti
P932PMC publication ID275449
P698PubMed publication ID14576318
P5875ResearchGate publication ID277376861

P50authorÁngel García DíazQ62743485
Lluis MontoliuQ56924908
P2093author name stringAngel Alonso
Antonio Martínez
Ana Busturia
Patricia Giraldo
Alfonso Lavado
Lucía Regales
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The beta-globin dominant control region activates homologous and heterologous promoters in a tissue-specific mannerQ69962041
A distal tyrosinase upstream element stimulates gene expression in neural-crest-derived melanocytes of transgenic mice: position-independent and mosaic expressionQ72714746
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Activation by locus control regions?Q33632344
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The Locus Control Region Is Necessary for Gene Expression in the Human β-Globin Locus but Not the Maintenance of an Open Chromatin Structure in Erythroid CellsQ33780942
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Rescue of the albino phenotype by introduction of a functional tyrosinase gene into mice.Q33921422
The human growth hormone locus control region mediates long-distance transcriptional activation independent of nuclear matrix attachment regionsQ33941426
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Human Matrix Attachment Regions Insulate Transgene Expression from Chromosomal Position Effects in Drosophila melanogasterQ33996776
The chicken lysozyme chromatin domain contains a second, widely expressed geneQ34012367
The su(Hw) protein insulates expression of the Drosophila melanogaster white gene from chromosomal position-effects.Q34042832
Position-effect protection and enhancer blocking by the chicken beta-globin insulator are separable activitiesQ34067751
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Size matters: use of YACs, BACs and PACs in transgenic animalsQ34220676
DNA position-specific repression of transcription by a Drosophila zinc finger proteinQ34237990
Analysis of perinatal gene expression: hormone response elements mediate activation of a lacZ reporter gene in liver of transgenic miceQ34315369
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A 5' element of the chicken beta-globin domain serves as an insulator in human erythroid cells and protects against position effect in DrosophilaQ34352447
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Insulators: many functions, many mechanisms.Q34515901
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Artificial chromosome transgenesis in pigmentary research.Q34722904
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The barrier function of an insulator couples high histone acetylation levels with specific protection of promoter DNA from methylationQ35778363
The beta-globin locus control region enhances transcription of but does not confer position-independent expression onto the lacZ gene in transgenic mice.Q35903407
Multiple transcripts of the mouse tyrosinase gene are generated by alternative splicingQ36061777
Position-independent transgene expression mediated by boundary elements from the apolipoprotein B chromatin domainQ36566546
Positional enhancer-blocking activity of the chicken beta-globin insulator in transiently transfected cellsQ36745009
A group of scs elements function as domain boundaries in an enhancer-blocking assayQ36815755
The sequence of a large L1Md element reveals a tandemly repeated 5' end and several features found in retrotransposonsQ36908687
Expression of the mouse tyrosinase gene during embryonic development: recapitulation of the temporal regulation in transgenic miceQ36922702
Sequences required for enhancer blocking activity of scs are located within two nuclease-hypersensitive regions.Q37640032
Chromatin structure and gene activityQ37944401
Position effects on eukaryotic gene expressionQ38023539
The mouse tyrosinase gene. Promoter modulation by positive and negative regulatory elements.Q38302222
The gypsy insulator can act as a promoter-specific transcriptional stimulatorQ39528891
Genomic targeting of methylated DNA: influence of methylation on transcription, replication, chromatin structure, and histone acetylationQ39540147
Coupling of enhancer and insulator properties identified in two retrotransposons modulates their mutagenic impact on nearby genesQ39681351
Chromatin domains as potential units of eukaryotic gene functionQ40672440
Effect of the Rabbit αs1-Casein Gene Distal Enhancer on the Expression of a Reporter Gene in Vitro and in VivoQ40758822
A cell-specific enhancer far upstream of the mouse tyrosinase gene confers high level and copy number-related expression in transgenic miceQ40792436
A locus control region at -12 kb of the tyrosinase geneQ41078425
Preferential insertion of P elements into genes expressed in the germ-line of Drosophila melanogasterQ41202645
A human retinal pigment epithelial cell line that retains epithelial characteristics after prolonged cultureQ41354392
The role of insulator elements in defining domains of gene expression.Q41441712
Cis-acting sequences regulating expression of the human alpha-globin cluster lie within constitutively open chromatinQ41623472
Stem cell gene therapy, position effects and chromatin insulators.Q41642138
Repression of hsp70 heat shock gene transcription by the suppressor of hairy-wing protein of Drosophila melanogasterQ41689099
Position-independent expression of the ovine beta-lactoglobulin gene in transgenic miceQ41855725
Variegated expression and delayed retinal pigmentation during development in transgenic mice with a deletion in the locus control region of the tyrosinase gene.Q43608205
Regulation of tyrosinase expression and activity in cultured human retinal pigment epithelial cellsQ44236043
Expression of the cut locus in the Drosophila wing margin is required for cell type specification and is regulated by a distant enhancerQ44897934
Specific protection of methylated CpGs in mammalian nucleiQ45193660
The 5' boundary of the human apolipoprotein B chromatin domain in intestinal cellsQ46433478
Physical Linkage of the Human Growth Hormone Gene Cluster and the CD79b (Igβ/B29) GeneQ48039278
Physical linkage of the human growth hormone gene cluster and the skeletal muscle sodium channel alpha-subunit gene (SCN4A) on chromosome 17.Q48069902
Association of the 5'HS4 sequence of the chicken beta-globin locus control region with human EF1 alpha gene promoter induces ubiquitous and high expression of human CD55 and CD59 cDNAs in transgenic rabbitsQ48118392
A yeast artificial chromosome covering the tyrosinase gene confers copy number-dependent expression in transgenic miceQ49150314
Beta-globin gene switching and DNase I sensitivity of the endogenous beta-globin locus in mice do not require the locus control regionQ52167088
Distal upstream tyrosinase S/MAR-containing sequence has regulatory properties specific to subsets of melanocytesQ52175843
Mosaicism of tyrosinase-locus transcription and chromatin structure in dark vs. light melanocyte clones of homozygouschinchilla-mottled miceQ52238874
Expansions of transgene repeats cause heterochromatin formation and gene silencing in DrosophilaQ52542203
P4510describes a project that usesImageQuantQ112270642
P433issue21
P407language of work or nameEnglishQ1860
P1104number of pages16
P304page(s)6290-6305
P577publication date2003-11-01
P1433published inNucleic Acids ResearchQ135122
P1476titleFunctional dissection of the mouse tyrosinase locus control region identifies a new putative boundary activity
P478volume31

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cites work (P2860)
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