Chronic exposure to arsenic in drinking water can lead to resistance to antimonial drugs in a mouse model of visceral leishmaniasis

scientific article published on 28 October 2013

Chronic exposure to arsenic in drinking water can lead to resistance to antimonial drugs in a mouse model of visceral leishmaniasis is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2013PNAS..11019932P
P356DOI10.1073/PNAS.1311535110
P932PMC publication ID3856816
P698PubMed publication ID24167266
P5875ResearchGate publication ID258117587

P50authorAlan FairlambQ4706598
Jörg FeldmannQ54652880
Susan WyllieQ56545158
Andrea RaabQ90783627
Meghan Rose PerryQ101062179
P2860cites workAntimonial treatment of visceral leishmaniasis: are current in vitro susceptibility assays adequate for prognosis of in vivo therapy outcome?Q56558896
Intracellular survival of Staphylococcus aureus due to alteration of cellular activity in arsenic and lead intoxicated mature Swiss albino miceQ78726954
The anti-trypanosome drug fexinidazole shows potential for treating visceral leishmaniasisQ24633734
Arsenic groundwater contamination in Middle Ganga Plain, Bihar, India: a future danger?Q24815356
Gene expression of inflammatory molecules in circulating lymphocytes from arsenic-exposed human subjects.Q24815894
Treatment options for visceral leishmaniasis: a systematic review of clinical studies done in India, 1980-2004Q28283745
Sodium stibogluconate (Pentostam) potentiates oxidant production in murine visceral leishmaniasis and in human bloodQ28344600
Antimonial resistance in Leishmania donovani is associated with increased in vivo parasite burdenQ28476400
Visceral leishmaniasis: what are the needs for diagnosis, treatment and control?Q29038941
Drug resistance in leishmaniasisQ29616242
Dose translation from animal to human studies revisitedQ29618049
Visceral leishmaniasis and arsenic: an ancient poison contributing to antimonial treatment failure in the Indian subcontinent?Q34043521
Role of metabolism in arsenic toxicityQ34085794
Did medicated salt hasten the spread of chloroquine resistance in Plasmodium falciparum?Q34355300
Management of visceral leishmaniasis in rural primary health care services in Bihar, IndiaQ34443655
Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agendaQ34768663
Impact of life stage and duration of exposure on arsenic-induced proliferative lesions and neoplasia in C3H miceQ36393258
Visceral leishmaniasis (kala-azar): challenges aheadQ36508336
Molecular mechanisms of antimony resistance in LeishmaniaQ36716130
Arsenic-induced carcinogenesis--oxidative stress as a possible mode of action and future research needs for more biologically based risk assessmentQ37662780
Visceral leishmaniasis: elimination with existing interventionsQ37859955
Leishmania antimony resistance: what we know what we can learn from the field.Q37907925
Clinical and parasite species risk factors for pentavalent antimonial treatment failure in cutaneous leishmaniasis in Peru.Q39185984
In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependentQ39444290
American tegumentary leishmaniasis: Is antimonial treatment outcome related to parasite drug susceptibility?Q39614525
Clinical risk factors for therapeutic failure in kala-azar patients treated with pentavalent antimonials in NepalQ40380970
New mechanisms of drug resistance in parasitic protozoaQ40945183
Novel mechanism of drug resistance in kala azar field isolatesQ42605042
Food intake, water intake, and drinking spout side preference of 28 mouse strainsQ43237768
Greatly enhanced arsenic shoot assimilation in rice leads to elevated grain levels compared to wheat and barleyQ46223842
Effect of chronic intake of arsenic-contaminated water on liverQ46556903
Analysis of T-cell proliferation and cytokine secretion in the individuals exposed to arsenicQ47390074
Refinement of techniques for the propagation of Leishmania donovani in hamsters.Q51810404
Assessment of lymphocyte subpopulations and cytokine secretion in children exposed to arsenic.Q53349595
LeishmaniasisQ54152502
High level arsenite resistance in Leishmania tarentolae is mediated by an active extrusion system.Q54196331
P433issue49
P407language of work or nameEnglishQ1860
P921main subjectarsenicQ871
drinking waterQ7892
visceral leishmaniasisQ2046113
P1104number of pages6
P304page(s)19932-19937
P577publication date2013-10-28
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleChronic exposure to arsenic in drinking water can lead to resistance to antimonial drugs in a mouse model of visceral leishmaniasis
P478volume110