Differences in Bcl-2 expression by T-cell subsets alter their balance after in vivo irradiation to favor CD4+Bcl-2hi NKT cells.

scientific article published on March 2009

Differences in Bcl-2 expression by T-cell subsets alter their balance after in vivo irradiation to favor CD4+Bcl-2hi NKT cells. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/EJI.200838657
P932PMC publication ID2758339
P698PubMed publication ID19197937
P5875ResearchGate publication ID23984239

P50authorJennifer Clare JonesQ55471994
P2093author name stringZhenyu Yao
Samuel Strober
Yinping Liu
P2860cites workBcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell deathQ24312211
Bcl-XL and Bcl-2 repress a common pathway of cell deathQ28505812
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hairQ28586758
CD1 recognition by mouse NK1+ T lymphocytesQ28591238
p53 is required for radiation-induced apoptosis in mouse thymocytesQ29620281
Recognition and function of Valpha14 NKT cellsQ34123059
Anti-apoptotic Bcl-2 proteins: structure, function and relevance for radiation biologyQ34795688
NKT cells are relatively resistant to apoptosisQ35751884
The diverse functions of CD1d-restricted NKT cells and their potential for immunotherapyQ36220141
Transplantation of allogeneic bone marrow without graft-versus-host disease using total lymphoid irradiationQ36340172
V alpha14 i NKT cells are innate lymphocytes that participate in the immune response to diverse microbesQ36354705
Mixed chimerism and permanent specific transplantation tolerance induced by a nonlethal preparative regimenQ36355970
Bad can act as a key regulator of T cell apoptosis and T cell development.Q36367710
A nonclassical non-Valpha14Jalpha18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillanceQ36403071
Identification of an early T cell progenitor for a pathway of T cell maturation in the bone marrowQ36746464
NKT cells: T lymphocytes with innate effector functionsQ36788766
Allograft Tolerance after Total Lymphoid Irradiation (TLI)Q39269419
Tolerance and chimerism after renal and hematopoietic-cell transplantationQ40428891
Host-residual invariant NK T cells attenuate graft-versus-host immunityQ43515226
bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytesQ44192187
Effect of KRN7000 on induced graft-vs-host diseaseQ44956752
Recipient CD4+ T cells that survive irradiation regulate chronic graft-versus-host diseaseQ47586153
IL-4-producing NK1.1+ T cells are resistant to glucocorticoid-induced apoptosis: implications for the Th1/Th2 balanceQ47757246
NKT cells: what's in a name?Q47895830
Systemic overexpression of BCL-2 in the hematopoietic system protects transgenic mice from the consequences of lethal irradiation.Q52188936
Host NKT cells can prevent graft-versus-host disease and permit graft antitumor activity after bone marrow transplantation.Q53555765
Down-regulation of the invariant Valpha14 antigen receptor in NKT cells upon activation.Q53905529
Monoclonal antibodies to promote marrow engraftment and tissue graft toleranceQ59074162
Stimulation of Host NKT Cells by Synthetic Glycolipid Regulates Acute Graft-versus-Host Disease by Inducing Th2 Polarization of Donor T CellsQ63363303
Host conditioning with total lymphoid irradiation and antithymocyte globulin prevents graft-versus-host disease: the role of CD1-reactive natural killer T cellsQ73544447
Requirement for Valpha14 NKT cells in IL-12-mediated rejection of tumorsQ73889862
Predominance of NK1.1+TCR alpha beta+ or DX5+TCR alpha beta+ T cells in mice conditioned with fractionated lymphoid irradiation protects against graft-versus-host disease: "natural suppressor" cellsQ74321466
Immune tolerance to combined organ and bone marrow transplants after fractionated lymphoid irradiation involves regulatory NK T cells and clonal deletionQ78488955
Augmentation of innate immunity by low-dose irradiationQ80124803
Protective conditioning for acute graft-versus-host diseaseQ81279975
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)763-775
P577publication date2009-03-01
P1433published inEuropean Journal of ImmunologyQ5412727
P1476titleDifferences in Bcl-2 expression by T-cell subsets alter their balance after in vivo irradiation to favor CD4+Bcl-2hi NKT cells
P478volume39

Reverse relations

cites work (P2860)
Q377291992-Gy whole-body irradiation significantly alters the balance of CD4+CD25−T effector cells and CD4+CD25+Foxp3+T regulatory cells in mice
Q47820461CD1d-Restricted pathways in hepatocytes control local natural killer T cell homeostasis and hepatic inflammation
Q88321753Enhanced Lymphodepletion Is Insufficient to Replace Exogenous IL2 or IL15 Therapy in Augmenting the Efficacy of Adoptively Transferred Effector CD8+ T Cells
Q37768104NKT cells, Treg, and their interactions in bone marrow transplantation
Q37610711Nonmyeloablative conditioning with total lymphoid irradiation and antithymocyte globulin: an update
Q42793688Recipient myeloid-derived immunomodulatory cells induce PD-1 ligand-dependent donor CD4+Foxp3+ regulatory T cell proliferation and donor-recipient immune tolerance after murine nonmyeloablative bone marrow transplantation
Q36462109Regulatory T Cell Immunotherapy in Immune-Mediated Diseases
Q38625892Selective resistance of CD44hi T cells to p53-dependent cell death results in persistence of immunologic memory after total body irradiation
Q37291642TLI and ATG conditioning with low risk of graft-versus-host disease retains antitumor reactions after allogeneic hematopoietic cell transplantation from related and unrelated donors
Q33914718The changed balance of regulatory and naive T cells promotes tolerance after TLI and anti-T-cell antibody conditioning
Q35662003Third-party CD4+ invariant natural killer T cells protect from murine GVHD lethality
Q52801888Tolerogenic interactions between CD8+ dendritic cells and NKT cells prevent rejection of bone marrow and organ grafts.
Q37894465Translational studies in hematopoietic cell transplantation: treatment of hematologic malignancies as a stepping stone to tolerance induction
Q36727857Use of hematopoietic cell transplants to achieve tolerance in patients with solid organ transplants

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