Phosphatidylinositol 3-kinase is not required for recycling of mannose 6-phosphate receptors from late endosomes to the trans-Golgi network

scientific article published on April 1997

Phosphatidylinositol 3-kinase is not required for recycling of mannose 6-phosphate receptors from late endosomes to the trans-Golgi network is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1091/MBC.8.4.577
P932PMC publication ID276110
P698PubMed publication ID9247639
P5875ResearchGate publication ID13971584

P2093author name stringS R Pfeffer
Y Nakajima
P2860cites workInhibitors of phosphoinositide 3-kinase block exocytosis but not endocytosis of transferrin receptors in 3T3-L1 adipocytesQ42826738
Rab-GDI presents functional Rab9 to the intracellular transport machinery and contributes selectivity to Rab9 membrane recruitment.Q45984799
Selective recycling of the mannose 6-phosphate/IGF-II receptor to the trans Golgi network in vitroQ46562898
Phosphoinositide 3-kinases and membrane trafficQ47986385
Disruption of PDGF receptor trafficking by mutation of its PI-3 kinase binding sites.Q52516078
The mannose 6-phosphate receptor and the biogenesis of lysosomesQ57960197
Translocation across Golgi vesicle membranes: a CHO glycosylation mutant deficient in CMP-sialic acid transportQ70669682
The effect of wortmannin on the localisation of lysosomal type I integral membrane glycoproteins suggests a role for phosphoinositide 3-kinase activity in regulating membrane traffic late in the endocytic pathwayQ71287476
Blockage of chemotactic peptide-induced stimulation of neutrophils by wortmannin as a result of selective inhibition of phosphatidylinositol 3-kinaseQ72237914
Intracellular movement of two mannose 6-phosphate receptors: return to the Golgi apparatusQ24679792
Lysosome biogenesis requires Rab9 function and receptor recycling from endosomes to the trans-Golgi networkQ28609803
Rab9 functions in transport between late endosomes and the trans Golgi networkQ28609814
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002)Q28640016
The biogenesis of lysosomesQ29617860
Evidence for phosphatidylinositol 3-kinase as a regulator of endocytosis via activation of Rab5.Q33826723
Structure and function of the mannose 6-phosphate/insulinlike growth factor II receptorsQ34236758
Inhibition of histamine secretion by wortmannin through the blockade of phosphatidylinositol 3-kinase in RBL-2H3 cells.Q34290591
Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cellsQ36382633
Wortmannin alters the transferrin receptor endocytic pathway in vivo and in vitroQ37379940
Biosynthesis and turnover of the mannose 6-phosphate receptor in cultured Chinese hamster ovary cellsQ38354695
Vacuolar biogenesis in yeast: sorting out the sorting proteins.Q40430579
A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuoleQ40872969
Receptor-mediated protein sorting to the vacuole in yeast: roles for a protein kinase, a lipid kinase and GTP-binding proteinsQ41020937
Wortmannin, an inhibitor of phosphoinositide 3-kinase, inhibits transcytosis in polarized epithelial cellsQ41269307
Phosphatidylinositol 3-kinase activity is required for early endosome fusion.Q41290141
Phosphatidylinositol 3-kinase activity is required at a postendocytic step in platelet-derived growth factor receptor traffickingQ41336419
Characterization of a phosphatidylinositol-specific phosphoinositide 3-kinase from mammalian cellsQ41485226
Wortmannin causes mistargeting of procathepsin D. evidence for the involvement of a phosphatidylinositol 3-kinase in vesicular transport to lysosomesQ41680092
Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses.Q41966849
Inhibition of the translocation of GLUT1 and GLUT4 in 3T3-L1 cells by the phosphatidylinositol 3-kinase inhibitor, wortmanninQ42084895
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)577-582
P577publication date1997-04-01
P1433published inMolecular Biology of the CellQ2338259
P1476titlePhosphatidylinositol 3-kinase is not required for recycling of mannose 6-phosphate receptors from late endosomes to the trans-Golgi network
P478volume8

Reverse relations

cites work (P2860)
Q41920146Biosynthesis and processing of cathepsin K in cultured human osteoclasts
Q40944427Cell polarization is required for ricin sensitivity in a Caco-2 cell line selected for ricin resistance
Q36301546Chimeric forms of furin and TGN38 are transported with the plasma membrane in the trans-Golgi network via distinct endosomal pathways
Q44614849Inhibition of Drynariae Rhizoma extracts on bone resorption mediated by processing of cathepsin K in cultured mouse osteoclasts
Q46703795Inhibition of Ulmus davidiana Planch (Ulmaceae) on bone resorption mediated by processing of cathepsin K in cultured mouse osteoclasts
Q41090087Inhibition of calcium-independent mannose 6-phosphate receptor incorporation into trans-Golgi network-derived clathrin-coated vesicles by wortmannin
Q38610585Inhibition of endosome fusion by wortmannin persists in the presence of activated Rab5.
Q42992153Molecular aspects of the endocytic pathway
Q28347849Overexpression of a rat kinase-deficient phosphoinositide 3-kinase, Vps34p, inhibits cathepsin D maturation
Q39286483Phosphatidylinositol 3-kinase and Rab5 GTPase inversely regulate the Smad anchor for receptor activation (SARA) protein independently of transforming growth factor-β1.
Q52168541Protein traffic from the secretory pathway to the endosomal system in pancreatic beta-cells.
Q30307233Resting (basal) secretion of proteins is provided by the minor regulated and constitutive-like pathways and not granule exocytosis in parotid acinar cells
Q47828341Sorting of lysosomal membrane glycoproteins lamp-1 and lamp-2 into vesicles distinct from mannose 6-phosphate receptor/gamma-adaptin vesicles at the trans-Golgi network.
Q41734067Sorting out adaptors
Q38969723Subcellular localisation of retromer in post-endocytic pathways of polarised Madin-Darby canine kidney cells

Search more.