Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer

scientific article published on 22 August 2016

Genetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer is …
instance of (P31):
scholarly articleQ13442814
meta-analysisQ815382

External links are
P356DOI10.1158/1055-9965.EPI-16-0147
P932PMC publication ID5093082
P698PubMed publication ID27550749

P50authorSean C DowdyQ114341797
Jeroen DepreeuwQ114341800
Matthias RübnerQ114374960
National Study of Endometrial Cancer Genetics Group (NSECG)Q114374965
Australian National Endometrial Cancer Study Group (ANECS)Q114374967
for RENDOCASQ114374977
Ingo B. RunnebaumQ1336242
Julian PetoQ6307461
Shirley HodgsonQ15995134
Jenny Chang-ClaudeQ21263057
Graham GilesQ30524411
Diether LambrechtsQ26923514
Helga SalvesenQ27506003
Kamila CzeneQ28484009
Angela CoxQ28484012
Hiltrud BrauchQ28484013
Barbara BurwinkelQ28484015
Hermann BrennerQ28958315
Alison DunningQ30506457
Amanda SpurdleQ45904058
Tracy O'MaraQ47503150
Matthias DürstQ50033778
Alexander HeinQ52723502
Shahana AhmedQ54208457
Stacey J WinhamQ56516227
John HopperQ56726496
Julie M. CunninghamQ67440680
Matthias W. BeckmannQ72940290
Deborah ThompsonQ73218846
John AttiaQ35705638
Kyriaki MichailidouQ37070465
Thilo DörkQ37342847
Vessela KristensenQ37344701
Jingmei LiQ37371985
Sarah E. MedlandQ37375476
Penelope M. WebbQ41235493
Jone TrovikQ42385777
Brooke L FridleyQ86514651
Jodie N PainterQ88243691
Ellen L GoodeQ88243694
Patrick NevenQ90004173
Elizabeth HollidayQ90063399
Frédéric AmantQ90141632
Peter HillemannsQ91084009
Jonathan P TyrerQ91084019
Miriam MintsQ94995287
Mark McevoyQ110251307
Manjeet K BollaQ114270702
Mitul ShahQ114292631
Hatef DarabiQ114292651
Maggie GormanQ114341767
Geoffrey OttonQ114341794
Katie AshtonQ114341796
Henrica M J WernerQ114341798
Joe DennisQ56875626
Daniela AnnibaliQ57568086
Tormund S NjølstadQ57568095
Douglas F. EastonQ59812154
Emma ThamQ59941710
Anthony SwerdlowQ60492223
Paul D P PharoahQ61822938
Per HallQ62593354
Alfons MeindlQ63015490
Fergus J. CouchQ63018779
Ian TomlinsonQ63213090
Peter A. FaschingQ64005064
Arif B. EkiciQ64409983
Annika LindblomQ64516098
P2093author name stringLouise Marquart
Qin Wang
Rodney J Scott
Timothy Cheng
Lynn Martin
Catherine S Healey
Anthony Proietto
AOCS Group
P2860cites workMeasuring adiposity in patients: the utility of body mass index (BMI), percent body fat, and leptinQ21090935
A flexible and accurate genotype imputation method for the next generation of genome-wide association studiesQ21129496
Genetic studies of body mass index yield new insights for obesity biologyQ22305005
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distributionQ34142739
Association of type 2 diabetes susceptibility variants with advanced prostate cancer risk in the Breast and Prostate Cancer Cohort ConsortiumQ34314362
Anthropometric measures at different ages and endometrial cancer risk.Q34745914
Obesity in relation to endometrial cancer risk and disease characteristics in the Women's Health InitiativeQ34850346
Fine-mapping of the HNF1B multicancer locus identifies candidate variants that mediate endometrial cancer riskQ35063160
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsQ24550675
The NHGRI GWAS Catalog, a curated resource of SNP-trait associationsQ24568334
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012Q27861047
Large-scale genotyping identifies 41 new loci associated with breast cancer riskQ29416989
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33Q29417032
Genome-wide association study identifies a common variant associated with risk of endometrial cancerQ29417135
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass indexQ29547208
METAL: fast and efficient meta-analysis of genomewide association scansQ29547217
Appropriate body-mass index for Asian populations and its implications for policy and intervention strategiesQ29614505
Impact of weight change and weight cycling on risk of different subtypes of endometrial cancerQ46427223
Modeling interactions with known risk loci-a Bayesian model averaging approach.Q51629433
Prospective study of body fat distribution and the risk of endometrial cancer.Q55180142
Body Mass Index, Hormone Replacement Therapy, and Endometrial Cancer Risk: A Meta-AnalysisQ56525963
New genetic loci link adipose and insulin biology to body fat distributionQ35114362
Association of obesity-related genetic variants with endometrial cancer risk: a report from the Shanghai Endometrial Cancer Genetics StudyQ35636048
Mendelian Randomization Study of Body Mass Index and Colorectal Cancer RiskQ35815677
Body Mass Index Genetic Risk Score and Endometrial Cancer RiskQ35852637
Endometrial cancer risk factors by 2 main histologic subtypes: the NIH-AARP Diet and Health StudyQ36661765
Type I and II endometrial cancers: have they different risk factors?Q36977055
Anthropometric measures and the risk of endometrial cancer, overall and by tumor microsatellite status and histological subtype.Q37065996
Physical activity, adiposity, and risk of endometrial cancerQ37369286
Anthropometric factors and endometrial cancer risk: a systematic review and dose-response meta-analysis of prospective studiesQ38384434
Abdominal obesity and endometrial cancer in egyptian females with postmenopausal bleedingQ39621778
Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regressionQ40862437
Using multiple genetic variants as instrumental variables for modifiable risk factorsQ41931960
Anthropometric factors and risk of endometrial cancer: the European prospective investigation into cancer and nutritionQ56988247
Effect of Adiposity and Fat Distribution on Endometrial Cancer Risk in Shanghai WomenQ57405499
P433issue11
P921main subjectobesityQ12174
P304page(s)1503-1510
P577publication date2016-08-22
P1433published inCancer Epidemiology, Biomarkers & PreventionQ326334
P1476titleGenetic Risk Score Mendelian Randomization Shows that Obesity Measured as Body Mass Index, but not Waist:Hip Ratio, Is Causal for Endometrial Cancer
P478volume25

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cites work (P2860)
Q90334874Analysis of Promoter-Associated Chromatin Interactions Reveals Biologically Relevant Candidate Target Genes at Endometrial Cancer Risk Loci
Q57788631BMI and Mortality in UK Biobank: Revised Estimates Using Mendelian Randomization
Q42316242Body mass and cancer: genetics, endocrinology… and more
Q90018585Commentary: What can Mendelian randomization tell us about causes of cancer?
Q47568885Genetics of obesity: what genetic association studies have taught us about the biology of obesity and its complications
Q38664592Harmonisation of biobanking standards in endometrial cancer research
Q57170142Identification of nine new susceptibility loci for endometrial cancer
Q64958736Mendelian randomization studies of cancer risk: a literature review.
Q42628550Obesity and gynaecological and obstetric conditions: umbrella review of the literature.
Q55260964Prioritising Risk Factors for Type 2 Diabetes: Causal Inference through Genetic Approaches.
Q40167819Type 2 diabetes, adiposity and cancer morbidity and mortality risk taking into account competing risk of noncancer deaths in a prospective cohort setting

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