Highly cooperative recruitment of Ets-1 and release of autoinhibition by Pax5.

scientific article published on 17 July 2009

Highly cooperative recruitment of Ets-1 and release of autoinhibition by Pax5. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.JMB.2009.07.028
P8608Fatcat IDrelease_jsziybeqmvdfxatw3llq2aw6sm
P932PMC publication ID2763353
P698PubMed publication ID19616560
P5875ResearchGate publication ID26680410

P50authorCynthia WolbergerQ30069608
James R HagmanQ56697325
P2093author name stringDaniel Fitzsimmons
Kara Lukin
Ryan Lutz
Colin W Garvie
P2860cites workThe highly conserved beta-hairpin of the paired DNA-binding domain is required for assembly of Pax-Ets ternary complexesQ24554523
Structural studies of Ets-1/Pax5 complex formation on DNAQ27637169
Structural analysis of the autoinhibition of Ets-1 and its role in protein partnershipsQ27639627
The structure of GABPalpha/beta: an ETS domain- ankyrin repeat heterodimer bound to DNAQ27748848
VMD: visual molecular dynamicsQ27860554
The partial homeodomain of the transcription factor Pax-5 (BSAP) is an interaction motif for the retinoblastoma and TATA-binding proteinsQ28141122
Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testisQ28263987
An inhibitory carboxyl-terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 geneQ28586875
Variable control of Ets-1 DNA binding by multiple phosphates in an unstructured regionQ28910227
The structural and dynamic basis of Ets-1 DNA binding autoinhibition.Q30978213
Interaction of murine ets-1 with GGA-binding sites establishes the ETS domain as a new DNA-binding motifQ30990862
BSAP can repress enhancer activity by targeting PU.1 functionQ33786904
Highly conserved amino acids in Pax and Ets proteins are required for DNA binding and ternary complex assemblyQ33948400
Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site.Q34740831
Autoinhibitory domains: modular effectors of cellular regulationQ34762527
Phosphorylation represses Ets-1 DNA binding by reinforcing autoinhibitionQ35186188
Requirements for selective recruitment of Ets proteins and activation of mb-1/Ig-alpha gene transcription by Pax-5 (BSAP).Q36119642
Early B-cell factor 'pioneers' the way for B-cell developmentQ36199350
Transcription factors drive B cell developmentQ36390003
Characterization of the cooperative function of inhibitory sequences in Ets-1.Q36559022
Cooperative binding of Ets-1 and core binding factor to DNAQ36644903
The transcription factor Fli-1 modulates marginal zone and follicular B cell development in miceQ36825143
The transcriptional regulation of B cell lineage commitment.Q36854605
Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5.Q37256859
Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factorsQ37592367
Different domains of the transcription factor ELF3 are required in a promoter-specific manner and multiple domains control its binding to DNA.Q38306980
DNA binding by c-Ets-1, but not v-Ets, is repressed by an intramolecular mechanismQ38330831
Convergence of Ets- and notch-related structural motifs in a heteromeric DNA binding complexQ38333812
Cooperative interaction of ets-1 with USF-1 required for HIV-1 enhancer activity in T cells.Q41047792
Pax and vertebrate developmentQ41059979
Inhibition of Ets-1 DNA binding and ternary complex formation between Ets-1, NF-kappaB, and DNA by a designed DNA-binding ligandQ41647351
Chromosomal translocations involving paired box transcription factors in human cancerQ41756456
Inhibitory module of Ets-1 allosterically regulates DNA binding through a dipole-facilitated phosphate contactQ43786814
Pax5/BSAP maintains the identity of B cells in late B lymphopoiesis.Q51065317
Transcription factor Pax5 activates the chromatin of key genes involved in B cell signaling, adhesion, migration, and immune function.Q51578905
DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site.Q52222420
Expression of Pax gene family members in the anthozoan cnidarian, Nematostella vectensis.Q54562012
Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAPQ58326934
The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequenceQ68624466
Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoterQ71524910
Modulation of transcription factor Ets-1 DNA binding: DNA-induced unfolding of an alpha helixQ71768221
A direct physical association between ETS and AP-1 transcription factors in normal human T cellsQ71992413
The alpha and beta subunits of the GA-binding protein form a stable heterodimer in solution. Revised model of heterotetrameric complex assemblyQ73538365
The transcription factor GABP is a critical regulator of B lymphocyte developmentQ80177664
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectautoinhibitionQ60728737
P304page(s)452-464
P577publication date2009-07-17
P1433published inJournal of Molecular BiologyQ925779
P1476titleHighly cooperative recruitment of Ets-1 and release of autoinhibition by Pax5
P478volume392

Reverse relations

cites work (P2860)
Q27679088Autoinhibition of ETV6 (TEL) DNA Binding: Appended Helices Sterically Block the ETS Domain
Q41555169Autoinhibition of ETV6 DNA Binding Is Established by the Stability of Its Inhibitory Helix
Q38696706ETV4 and AP1 Transcription Factors Form Multivalent Interactions with three Sites on the MED25 Activator-Interacting Domain
Q36074924Gene deregulation and chronic activation in natural killer cells deficient in the transcription factor ETS1
Q37872764Genomic and biochemical insights into the specificity of ETS transcription factors
Q26829833Molecular mechanisms of ETS transcription factor-mediated tumorigenesis
Q47976593Multiple DNA-binding modes for the ETS family transcription factor PU.1.
Q35768281PAX3 and ETS1 synergistically activate MET expression in melanoma cells
Q36794564Review of Ets1 structure, function, and roles in immunity
Q48115869Signatures of DNA target selectivity by ETS transcription factors
Q27680868Steric Mechanism of Auto-Inhibitory Regulation of Specific and Non-Specific DNA Binding by the ETS Transcriptional Repressor ETV6
Q38264349The transcription factor ETS1 in lymphomas: friend or foe?
Q59357668Transcription Factor ETS-1 and Reactive Oxygen Species: Role in Vascular and Renal Injury