| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1002/DMRR.945 |
| P698 | PubMed publication ID | 19214972 |
| P2093 | author name string | Ciriaco A Piccirillo | |
| Evridiki Sgouroudis | |||
| P2860 | cites work | CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells | Q74012969 |
| Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells | Q74244102 | ||
| Activation of natural killer T cells by alpha-galactosylceramide treatment prevents the onset and recurrence of autoimmune Type 1 diabetes | Q74455329 | ||
| Damage control, rather than unresponsiveness, effected by protective DX5+ T cells in autoimmune diabetes | Q77192908 | ||
| Essential Role for STAT5 Signaling in CD25+CD4+ Regulatory T Cell Homeostasis and the Maintenance of Self-Tolerance | Q79074354 | ||
| Dynamics of pathogenic and suppressor T cells in autoimmune diabetes development | Q79125427 | ||
| CD4+Foxp3+ regulatory T cells in the control of autoimmunity: in vivo veritas | Q79623493 | ||
| Impact of protective IL-2 allelic variants on CD4+ Foxp3+ regulatory T cell function in situ and resistance to autoimmune diabetes in NOD mice | Q79675252 | ||
| No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes | Q79843142 | ||
| Function of the IL-2R for thymic and peripheral CD4+CD25+ Foxp3+ T regulatory cells | Q79984749 | ||
| Toward further mapping of the association between the IL2RA locus and type 1 diabetes | Q80065270 | ||
| Decreased blood dendritic cell counts in type 1 diabetic children | Q80226211 | ||
| Toward cell-based therapy of type I diabetes | Q80464970 | ||
| Murine CD4+CD25+ regulatory T cells fail to undergo chromatin remodeling across the proximal promoter region of the IL-2 gene | Q80833054 | ||
| Dendritic cells and macrophages are essential for the retention of lymphocytes in (peri)-insulitis of the nonobese diabetic mouse: a phagocyte depletion study | Q81282208 | ||
| CD4+CD25high regulatory T cells in human autoimmune diabetes | Q81428869 | ||
| Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse | Q24290693 | ||
| Foxp3 occupancy and regulation of key target genes during T-cell stimulation | Q24623384 | ||
| Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction | Q24650734 | ||
| Control of regulatory T cell development by the transcription factor Foxp3 | Q27860489 | ||
| Foxp3 programs the development and function of CD4+CD25+ regulatory T cells | Q27860714 | ||
| B7/CD28 costimulation is essential for the homeostasis of the CD4+CD25+ immunoregulatory T cells that control autoimmune diabetes | Q28143530 | ||
| Hassall's corpuscles instruct dendritic cells to induce CD4+CD25+ regulatory T cells in human thymus | Q28268867 | ||
| Multiple immuno-regulatory defects in type-1 diabetes | Q28344695 | ||
| Where CD4+CD25+ T reg cells impinge on autoimmune diabetes | Q28506933 | ||
| An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoires | Q28590409 | ||
| A function for interleukin 2 in Foxp3-expressing regulatory T cells | Q28590646 | ||
| Interleukin-10-deficient mice develop chronic enterocolitis | Q29547881 | ||
| The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3 | Q29619324 | ||
| CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production | Q29619536 | ||
| Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of mice | Q29622850 | ||
| Dendritic cells induce peripheral T cell unresponsiveness under steady state conditions in vivo | Q30080006 | ||
| Regulatory T-cell, endogenous antigen and neonatal environment in the prevention and induction of autoimmune disease | Q30308291 | ||
| Visualizing regulatory T cell control of autoimmune responses in nonobese diabetic mice | Q30498716 | ||
| In situ characterization of dendritic cells occurring in the islets of nonobese diabetic mice during the development of insulitis | Q30858273 | ||
| The role of CD4 and CD8 T cells in the development of autoimmune diabetes | Q33767929 | ||
| Interleukin-2 gene variation impairs regulatory T cell function and causes autoimmunity | Q33918375 | ||
| Is it dietary insulin? | Q34001178 | ||
| Tumor necrosis factor-alpha regulation of CD4+CD25+ T cell levels in NOD mice | Q34155881 | ||
| Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells | Q34189120 | ||
| Is pancreas development abnormal in the non-obese diabetic mouse, a spontaneous model of type I diabetes? | Q34206509 | ||
| IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells | Q34318928 | ||
| Understanding autoimmune diabetes: insights from mouse models. | Q34498188 | ||
| Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes. | Q34553677 | ||
| Development and function of agonist-induced CD25+Foxp3+ regulatory T cells in the absence of interleukin 2 signaling | Q34561791 | ||
| Regulatory T cell-derived interleukin-10 limits inflammation at environmental interfaces | Q34590015 | ||
| B7-1 mediated costimulation regulates pancreatic autoimmunity | Q34763699 | ||
| Immunotherapy of the nonobese diabetic mouse: treatment with an antibody to T-helper lymphocytes | Q41789085 | ||
| The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens | Q42441813 | ||
| CD40/CD40L interaction regulates CD4+CD25+ T reg homeostasis through dendritic cell-produced IL-2. | Q42473719 | ||
| Regulatory T-cell therapy: is it ready for the clinic? | Q43513695 | ||
| Congenic mapping of the diabetogenic locus Idd4 to a 5.2-cM region of chromosome 11 in NOD mice: identification of two potential candidate subloci | Q43786589 | ||
| Cutting Edge: CD28 Controls Peripheral Homeostasis of CD4+CD25+ Regulatory T Cells | Q46025217 | ||
| Impairment of NK cell function by NKG2D modulation in NOD mice | Q46830266 | ||
| Interleukin-4 deficiency does not exacerbate disease in NOD mice | Q47690788 | ||
| Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. | Q51997055 | ||
| Distinct effects of STAT5 activation on CD4+ and CD8+ T cell homeostasis: development of CD4+CD25+ regulatory T cells versus CD8+ memory T cells. | Q52004102 | ||
| CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells. | Q52552727 | ||
| Functional waning of naturally occurring CD4+ regulatory T-cells contributes to the onset of autoimmune diabetes. | Q53522597 | ||
| An early age-related increase in the frequency of CD4+ Foxp3+ cells in BDC2.5NOD mice. | Q53559269 | ||
| Diabetes in non-obese diabetic mice is not associated with quantitative changes in CD4+ CD25+ Foxp3+ regulatory T cells. | Q53560161 | ||
| Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells. | Q53859655 | ||
| Cell-intrinsic effects of non-MHC NOD genes on dendritic cell generation in vivo. | Q53969367 | ||
| Uncoupling of IL-2 signaling from cell cycle progression in naive CD4+ T cells by regulatory CD4+CD25+ T lymphocytes. | Q54688372 | ||
| Genetic control of autoimmunity in type 1 diabetes | Q56593817 | ||
| B7-2 (CD86) controls the priming of autoreactive CD4 T cell response against pancreatic islets | Q56875361 | ||
| Blockade of CTLA-4 on CD4+CD25+ regulatory T cells abrogates their function in vivo | Q56901901 | ||
| HLA-D region β-chain DNA endonuclease fragments differ between HLA-DR identical healthy and insulin-dependent diabetic individuals | Q57449712 | ||
| Foxp3-dependent programme of regulatory T-cell differentiation | Q59084714 | ||
| CD4 + CD25 + Cells Controlling a Pathogenic CD4 Response Inhibit Cytokine Differentiation, CXCR-3 Expression, and Tissue Invasion | Q63346582 | ||
| Transfer of autoimmune diabetes mellitus with splenocytes from nonobese diabetic (NOD) mice | Q68889645 | ||
| Acceleration of the onset of diabetes in NOD mice by thymectomy at weaning | Q69510896 | ||
| The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus | Q71420898 | ||
| Defective maturation and function of antigen-presenting cells in type 1 diabetes | Q72559435 | ||
| Increased levels of cow's milk and beta-lactoglobulin antibodies in young children with newly diagnosed IDDM. The Childhood Diabetes in Finland Study Group | Q72890176 | ||
| Increased T cell autoreactivity in the absence of CD40-CD40 ligand interactions: a role of CD40 in regulatory T cell development | Q73311881 | ||
| Control of T cell hyperactivation in IL-2-deficient mice by CD4(+)CD25(-) and CD4(+)CD25(+) T cells: evidence for two distinct regulatory mechanisms | Q73955062 | ||
| The main function of IL-2 is to promote the development of T regulatory cells | Q35213797 | ||
| CD154 is a negative regulator of autoaggressive CD8+ T cells in type 1 diabetes | Q35318823 | ||
| A comprehensive guide to antibody and T-cell responses in type 1 diabetes. | Q35583448 | ||
| Resistance of the target islet tissue to autoimmune destruction contributes to genetic susceptibility in Type 1 diabetes | Q35634096 | ||
| Dendritic cells with TGF-beta1 differentiate naive CD4+CD25- T cells into islet-protective Foxp3+ regulatory T cells | Q35669757 | ||
| Nonobese diabetic mice express aspects of both type 1 and type 2 diabetes | Q35699988 | ||
| Adaptive TGF-beta-dependent regulatory T cells control autoimmune diabetes and are a privileged target of anti-CD3 antibody treatment | Q35748567 | ||
| Nonredundant roles for Stat5a/b in directly regulating Foxp3 | Q35828667 | ||
| Tolerance, not immunity, crucially depends on IL-2. | Q35877199 | ||
| The NOD mouse: a model of immune dysregulation | Q36072434 | ||
| A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor Foxp3. | Q36078042 | ||
| Mechanisms of suppression by suppressor T cells | Q36078047 | ||
| Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes | Q36156876 | ||
| Dendritic cell-expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice | Q36228938 | ||
| Differential effects of anti-B7-1 and anti-B7-2 monoclonal antibody treatment on the development of diabetes in the nonobese diabetic mouse | Q36364541 | ||
| CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells. | Q36366075 | ||
| Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells | Q36371345 | ||
| Development of spontaneous autoimmune peripheral polyneuropathy in B7-2-deficient NOD mice. | Q36376299 | ||
| CD4+CD25+ T regulatory cells dependent on ICOS promote regulation of effector cells in the prediabetic lesion | Q36399063 | ||
| CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes. | Q36399104 | ||
| Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization | Q36402763 | ||
| Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes | Q36403481 | ||
| Regulatory T-cell physiology and application to treat autoimmunity | Q36563537 | ||
| Hematopoietic stem-cell defects underlying abnormal macrophage development and maturation in NOD/Lt mice: defective regulation of cytokine receptors and protein kinase C. | Q36603252 | ||
| Thymic stromal lymphopoietin and thymic stromal lymphopoietin-conditioned dendritic cells induce regulatory T-cell differentiation and protection of NOD mice against diabetes | Q36807597 | ||
| TGFbeta signalling in control of T-cell-mediated self-reactivity | Q36831664 | ||
| Tolerogenic dendritic cells and the quest for transplant tolerance | Q36879029 | ||
| Genetic polymorphisms in susceptibility to Type 1 Diabetes | Q36982773 | ||
| Do the peptide-binding properties of diabetogenic class II molecules explain autoreactivity? | Q37033008 | ||
| Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target | Q37111968 | ||
| Unique role of CD4+CD62L+ regulatory T cells in the control of autoimmune diabetes in T cell receptor transgenic mice | Q37569990 | ||
| Antigen-specific FoxP3-transduced T-cells can control established type 1 diabetes | Q38333256 | ||
| Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells. | Q40051110 | ||
| Suppressor effector function of CD4+CD25+ immunoregulatory T cells is antigen nonspecific | Q40910998 | ||
| The non-obese diabetic (NOD) mouse: an animal model for autoimmune thyroiditis | Q41295082 | ||
| P433 | issue | 3 | |
| P921 | main subject | type-1 diabetes | Q124407 |
| P304 | page(s) | 208-218 | |
| P577 | publication date | 2009-03-01 | |
| P1433 | published in | Diabetes - Metabolism: Research and Reviews | Q15750056 |
| P1476 | title | Control of type 1 diabetes by CD4+Foxp3+ regulatory T cells: lessons from mouse models and implications for human disease | |
| P478 | volume | 25 |
| Q37403114 | Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma |
| Q50974904 | Bacille Calmette-Guérin/DNAhsp65 prime-boost is protective against diabetes in non-obese diabetic mice but not in the streptozotocin model of type 1 diabetes. |
| Q50929246 | CCL22 Prevents Rejection of Mouse Islet Allografts and Induces Donor-Specific Tolerance. |
| Q37664261 | Consumption of acidic water alters the gut microbiome and decreases the risk of diabetes in NOD mice. |
| Q84596471 | Current literature in diabetes |
| Q37583646 | Epigenetics: deciphering how environmental factors may modify autoimmune type 1 diabetes |
| Q35530818 | Evaluation of immunosuppressive function of regulatory T cells using a novel in vitro cytotoxicity assay |
| Q36591189 | Expression of a ricin toxin B subunit: insulin fusion protein in edible plant tissues |
| Q38302612 | Extracorporeal photopheresis as a therapy for autoimmune diseases. |
| Q41919734 | FOXP3⁺ T regulatory cell modifications in inflammatory bowel disease patients treated with anti-TNFα agents |
| Q35666030 | Fatal pancreatitis in simian immunodeficiency virus SIV(mac251)-infected macaques treated with 2',3'-dideoxyinosine and stavudine following cytotoxic-T-lymphocyte-associated antigen 4 and indoleamine 2,3-dioxygenase blockade |
| Q42790184 | Forced expression of programmed death-1 gene on T cell decreased the incidence of type 1 diabetes |
| Q92340565 | Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology |
| Q30039774 | Glucagon-like peptide-1 receptor signalling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells |
| Q41365175 | IL-2 as a therapeutic target for the restoration of Foxp3+ regulatory T cell function in organ-specific autoimmunity: implications in pathophysiology and translation to human disease |
| Q33696522 | Immune modulation by Schistosoma mansoni antigens in NOD mice: effects on both innate and adaptive immune systems |
| Q33907609 | Immune tolerance induction by integrating innate and adaptive immune regulators |
| Q47285415 | Japanese herbal medicine TJ-48 prevents autoimmune diabetes in NOD mice |
| Q58855536 | Mast cells control insulitis and increase Treg cells to confer protection against STZ-induced type 1 diabetes in mice |
| Q33923377 | Maternal obesity exacerbates insulitis and type 1 diabetes in non-obese diabetic mice |
| Q37737987 | Mouse models for the study of autoimmune type 1 diabetes: a NOD to similarities and differences to human disease |
| Q35107187 | Premature CD4+ T cell aging and its contribution to lymphopenia-induced proliferation of memory cells in autoimmune-prone non-obese diabetic mice |
| Q35142798 | Prevention of murine autoimmune diabetes by CCL22-mediated Treg recruitment to the pancreatic islets |
| Q37760872 | Processing and presentation of (pro)-insulin in the MHC class II pathway: the generation of antigen-based immunomodulators in the context of type 1 diabetes mellitus |
| Q34213205 | Restoration of the unfolded protein response in pancreatic β cells protects mice against type 1 diabetes |
| Q33683730 | Six months of diazoxide treatment at bedtime in newly diagnosed subjects with type 1 diabetes does not influence parameters of {beta}-cell function and autoimmunity but improves glycemic control |
| Q51177622 | Surge in regulatory T cells does not prevent onset of hyperglycemia in NOD mice: immune profiles do not correlate with disease severity |
| Q37006155 | Targeting regulatory T cells in the treatment of type 1 diabetes mellitus |
| Q37968302 | The influence of the microbiota on type-1 diabetes: on the threshold of a leap forward in our understanding |
| Q36637650 | Thioreductase-Containing Epitopes Inhibit the Development of Type 1 Diabetes in the NOD Mouse Model |
| Q36601077 | Transcriptome profiling of human FoxP3+ regulatory T cells |
| Q37972675 | Type 1 diabetes: role of intestinal microbiome in humans and mice |
| Q50449976 | Undifferentiated Wharton's Jelly Mesenchymal Stem Cell Transplantation Induces Insulin-Producing Cell Differentiation and Suppression of T-Cell-Mediated Autoimmunity in Nonobese Diabetic Mice |
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