Secondary lymphoid organs: responding to genetic and environmental cues in ontogeny and the immune response

scientific article published on August 2009

Secondary lymphoid organs: responding to genetic and environmental cues in ontogeny and the immune response is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.4049/JIMMUNOL.0804324
P932PMC publication ID2766168
P698PubMed publication ID19661265
P5875ResearchGate publication ID26723286

P50authorNancy RuddleQ63662154
P2093author name stringEitan M Akirav
P2860cites workRANK is essential for osteoclast and lymph node developmentQ24598872
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The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17+ T helper cellsQ27860620
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An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cellsQ28235728
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A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleenQ28300225
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Lymphotoxin-alpha-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsivenessQ28510392
Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesisQ28511182
Lymphatic endothelial cell identity is reversible and its maintenance requires Prox1 activityQ28584887
Overlapping roles of CXCL13, interleukin 7 receptor alpha, and CCR7 ligands in lymph node developmentQ28585776
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OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Prox1 induces lymphatic endothelial differentiation via integrin alpha9 and other signaling cascadesQ30479201
Chemokines and cell migration in secondary lymphoid organsQ33807114
Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2.Q33854381
Anatomical basis of tolerance and immunity to intestinal antigensQ33965210
Lymphocyte homing to bronchus-associated lymphoid tissue (BALT) is mediated by L-selectin/PNAd, alpha4beta1 integrin/VCAM-1, and LFA-1 adhesion pathwaysQ34198405
Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.Q34307135
Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleenQ34488105
Isolated lymphoid follicles can function as sites for induction of mucosal immune responsesQ34554635
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Role of T and NK cells and IL7/IL7r interactions during neonatal maturation of lymph nodesQ35037300
Lymphotoxin plays a crucial role in the development and function of nasal-associated lymphoid tissue through regulation of chemokines and peripheral node addressinQ35083503
Organogenesis of lymphoid tissuesQ35096187
Dendritic Cell Function in Vivo during the Steady State: A Role in Peripheral ToleranceQ35119879
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Lymphoid precursors in intestinal cryptopatches express CCR6 and undergo dysregulated development in the absence of CCR6Q73827790
Developing lymph nodes collect CD4+CD3- LTbeta+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cellsQ73838320
Essential role of IL-7 receptor alpha in the formation of Peyer's patch anlageQ74261728
Initiation of NALT organogenesis is independent of the IL-7R, LTbetaR, and NIK signaling pathways but requires the Id2 gene and CD3(-)CD4(+)CD45(+) cellsQ74548133
Different cytokines induce surface lymphotoxin-alphabeta on IL-7 receptor-alpha cells that differentially engender lymph nodes and Peyer's patchesQ78651212
Lymphotoxin-independent expression of TNF-related activation-induced cytokine by stromal cells in cryptopatches, isolated lymphoid follicles, and Peyer's patchesQ80178390
Intestinal cryptopatch formation in mice requires lymphotoxin alpha and the lymphotoxin beta receptorQ81111365
Conduit for privileged communications in the lymph nodeQ81304835
Novel tumor necrosis factor-knockout mice that lack Peyer's patchesQ81653276
Regulation of peripheral lymph node genesis by the tumor necrosis factor family member TRANCEQ36368551
Lymph-borne chemokines and other low molecular weight molecules reach high endothelial venules via specialized conduits while a functional barrier limits access to the lymphocyte microenvironments in lymph node cortexQ36368559
The CCR7 ligand elc (CCL19) is transcytosed in high endothelial venules and mediates T cell recruitmentQ36369301
Ectopic LTαβ Directs Lymphoid Organ Neogenesis with Concomitant Expression of Peripheral Node Addressin and a HEV-restricted SulfotransferaseQ36370988
Lymphoid organ development: from ontogeny to neogenesisQ36426808
Development and function of the mammalian spleen.Q36709430
Th17 cell differentiation: the long and winding roadQ37133442
A developmental switch in lymphocyte homing receptor and endothelial vascular addressin expression regulates lymphocyte homing and permits CD4+ CD3- cells to colonize lymph nodesQ37307203
Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxin beta in mesenteric lymph node genesisQ38288045
The conduit system transports soluble antigens from the afferent lymph to resident dendritic cells in the T cell area of the lymph nodeQ38459394
Organizer-like reticular stromal cell layer common to adult secondary lymphoid organsQ39926763
LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagenQ39986041
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-kappa b-inducing kinaseQ40954925
Lymphotoxin alpha3 induces chemokines and adhesion molecules: insight into the role of LT alpha in inflammation and lymphoid organ developmentQ40986515
Lymphotoxin beta receptor triggering induces activation of the nuclear factor kappaB transcription factor in some cell typesQ41159609
RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medullaQ41868543
Lymphotoxin-beta receptor signaling is required for the homeostatic control of HEV differentiation and functionQ42486404
Cytotoxicity mediated by soluble antigen and lymphocytes in delayed hypersensitivity. II. Correlation of the in vitro response with skin reactivityQ42775143
The histogenesis of lymph nodes in rat and rabbitQ43713709
Cutting edge: organogenesis of nasal-associated lymphoid tissue (NALT) occurs independently of lymphotoxin-alpha (LT alpha) and retinoic acid receptor-related orphan receptor-gamma, but the organization of NALT is LT alpha dependentQ43860707
Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses.Q44894318
MAdCAM-1 expressing sacral lymph node in the lymphotoxin beta-deficient mouse provides a site for immune generation following vaginal herpes simplex virus-2 infectionQ45611482
Human fetal lymphoid tissue-inducer cells are interleukin 17-producing precursors to RORC+ CD127+ natural killer-like cellsQ46231038
Lymph node genesis is induced by signaling through the lymphotoxin beta receptorQ47713223
The lymphotoxin beta receptor controls organogenesis and affinity maturation in peripheral lymphoid tissuesQ47713235
Synchrony of high endothelial venules and lymphatic vessels revealed by immunization.Q50476530
Expression of alpha(4)beta(7) integrin defines a distinct pathway of lymphoid progenitors committed to T cells, fetal intestinal lymphotoxin producer, NK, and dendritic cells.Q51063633
Distinct activities of stromal cells involved in the organogenesis of lymph nodes and Peyer's patches.Q51981354
Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis.Q51984858
Ectopic lymphoid-organ development occurs through interleukin 7-mediated enhanced survival of lymphoid-tissue-inducer cells.Q51985115
Inducible lymphoid tissues in the adult gut: recapitulation of a fetal developmental pathway?Q52051919
Induction of secondary and tertiary lymphoid structures in the skin.Q52085787
I kappa B kinase complex alpha kinase activity controls chemokine and high endothelial venule gene expression in lymph nodes and nasal-associated lymphoid tissue.Q52085932
Presumptive lymph node organizers are differentially represented in developing mesenteric and peripheral nodes.Q52087999
Developmental defects of lymphoid cells in Jak3 kinase-deficient mice.Q52204302
Restoration of lymphoid organ integrity through the interaction of lymphoid tissue-inducer cells with stroma of the T cell zone.Q52586488
Cutting edge: Uniqueness of lymphoid chemokine requirement for the initiation and maturation of nasopharynx-associated lymphoid tissue organogenesis.Q53588599
Lymphocyte Cytotoxicity in vitro: Activation and Release of a Cytotoxic FactorQ59095839
Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17Q62735747
Function of CD4+CD3- cells in relation to B- and T-zone stroma in spleenQ63346578
TNF and lymphotoxin beta cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodesQ63968518
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)2205-2212
P577publication date2009-08-01
P1433published inJournal of ImmunologyQ3521441
P1476titleSecondary lymphoid organs: responding to genetic and environmental cues in ontogeny and the immune response
P478volume183

Reverse relations

cites work (P2860)
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