| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Angela M Podevels | |
| Michael G Thomas | |||
| Brian M Kevany | |||
| Yolande A Chan | |||
| P2860 | cites work | The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum | Q24534370 |
| Salmonella typhimurium LT2 catabolizes propionate via the 2-methylcitric acid cycle | Q24549164 | ||
| The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin | Q24561472 | ||
| Genetics of zwittermicin a production by Bacillus cereus | Q24630084 | ||
| Discovery and characterization of a marine bacterial SAM-dependent chlorinase | Q24652817 | ||
| Synthesis of C5-dicarboxylic acids from C2-units involving crotonyl-CoA carboxylase/reductase: the ethylmalonyl-CoA pathway | Q24669700 | ||
| Genome sequencing reveals complex secondary metabolome in the marine actinomycete Salinispora tropica | Q24669895 | ||
| Crystal structure of an Acyl-ACP dehydrogenase from the FK520 polyketide biosynthetic pathway: insights into extender unit biosynthesis | Q27642556 | ||
| Crystal structure and mechanism of a bacterial fluorinating enzyme | Q27643096 | ||
| The chalcone synthase superfamily of type III polyketide synthases | Q28183088 | ||
| The calicheamicin gene cluster and its iterative type I enediyne PKS | Q28218405 | ||
| Acetyl-coenzyme A carboxylase: crucial metabolic enzyme and attractive target for drug discovery | Q28257735 | ||
| Crystal structure of the beta-subunit of acyl-CoA carboxylase: structure-based engineering of substrate specificity | Q28290878 | ||
| Studies on the biosynthesis of 16-membered macrolide antibiotics using carbon-13 nuclear magnetic resonance spectroscopy | Q28316679 | ||
| A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages | Q28486798 | ||
| Biochemical and structural characterization of an essential acyl coenzyme A carboxylase from Mycobacterium tuberculosis | Q28486901 | ||
| Salinosporamide A: a highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus salinospora. | Q30764187 | ||
| The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units | Q47850876 | ||
| The biosynthetic gene cluster for the macrolactone ring of the immunosuppressant FK506. | Q48015320 | ||
| Cloning, sequencing, overexpression in Escherichia coli, and inactivation of the valine dehydrogenase gene in the polyether antibiotic producer Streptomyces cinnamonensis | Q48058791 | ||
| Organization of the biosynthetic gene cluster for the macrolide concanamycin A in Streptomyces neyagawaensis ATCC 27449. | Q48118274 | ||
| Effects of methylmalonyl-CoA mutase gene knockouts on erythromycin production in carbohydrate-based and oil-based fermentations of Saccharopolyspora erythraea. | Q51265599 | ||
| Transcarboxylase. VI. Kinetic analysis of the reaction mechanism. | Q53012634 | ||
| Biosynthetic studies of leptomycins. | Q54436482 | ||
| Unique butyric acid incorporation patterns for salinosporamides A and B reveal distinct biosynthetic origins. | Q55043490 | ||
| Modulation of Polyketide Synthase Activity by Accessory Proteins During Lovastatin Biosynthesis | Q60480995 | ||
| On the Biosynthetic Origin of Methoxymalonyl-Acyl Carrier Protein, the Substrate for Incorporation of “Glycolate” Units into Ansamitocin and Soraphen A | Q61859686 | ||
| Don't Classify Polyketide Synthases | Q61859759 | ||
| Isolation of galantins I and II, water-soluble basic peptides. Studies on antibiotics from the genus Bacillus. III | Q66909720 | ||
| Biosynthetic origin of the C2 units of geldanamycin and distribution of label from D-[6-13C]glucose | Q67563487 | ||
| Further studies on the biosynthesis of chlorothricin | Q68901710 | ||
| Biosynthesis of lasalocid A. Metabolic interrelationships of carboxylic acid precursors and polyether antibiotics | Q69620066 | ||
| Malonyl coenzyme A synthetase. Purification and properties | Q69943055 | ||
| Physical and genetic characterisation of the gene cluster for the antibiotic actinorhodin in Streptomyces coelicolor A3(2) | Q70158523 | ||
| Isolation and characterization of an acyl-coenzyme A carboxylase from an erythromycin-producing Streptomyces erythreus | Q70421628 | ||
| Regulation of biosynthesis of monensins on chemically defined medium | Q70512852 | ||
| The biosynthesis of monensin-A: thymine, beta-aminoisobutyrate and methacrylate metabolism in Streptomyces cinnamonensis | Q70889753 | ||
| Biosynthesis and the metabolic fate of carbon-14 labeled spiramycin I | Q71740782 | ||
| Biosynthesis of tetrocarcin. Incorporation of 14C- and 13C-labeled compounds into tetrocarcin | Q71796213 | ||
| Biosynthetic origin of carbons 3 and 4 of leucomycin aglycone | Q71796228 | ||
| Valine as a precursor of n-butyrate unit in the biosynthesis of macrolide aglycone | Q71796231 | ||
| Biosynthesis of monensins A and B | Q71796235 | ||
| The biotin carboxylase-biotin carboxyl carrier protein complex of Escherichia coli acetyl-CoA carboxylase | Q73496277 | ||
| Biosynthesis of the enediyne antitumor antibiotic C-1027 | Q74620798 | ||
| ANTIBIOTIC GLYCOSIDES. V. A COMPARISON OF 2-METHYLMALONATE AND PROPIONATE AS PERCURSORS OF THE C21 BRANCHED CHAIN LACTONE IN ERYTHROMYCIN | Q76960000 | ||
| Structures and biosynthesis of aflastatins: novel inhibitors of aflatoxin production by Aspergillus parasiticus | Q77904664 | ||
| Functional expression of genes involved in the biosynthesis of the novel polyketide chain extension unit, methoxymalonyl-acyl carrier protein, and engineered biosynthesis of 2-desmethyl-2-methoxy-6-deoxyerythronolide B | Q78066270 | ||
| Biosynthetic origin of the methoxyl extender unit in bafilomycin and concanamycin using stereospecifically labeled precursors | Q80052923 | ||
| Insertional Inactivation of Methylmalonyl Coenzyme A (CoA) Mutase and Isobutyryl-CoA Mutase Genes in Streptomyces cinnamonensis: Influence on Polyketide Antibiotic Biosynthesis | Q104910667 | ||
| Role of Crotonyl Coenzyme A Reductase in Determining the Ratio of Polyketides Monensin A and Monensin B Produced byStreptomyces cinnamonensis | Q105005532 | ||
| Iteration as programmed event during polyketide assembly; molecular analysis of the aureothin biosynthesis gene cluster | Q30886956 | ||
| Precursor supply for polyketide biosynthesis: the role of crotonyl-CoA reductase | Q31853504 | ||
| Plant polyketide synthases: a chalcone synthase-type enzyme which performs a condensation reaction with methylmalonyl-CoA in the biosynthesis of C-methylated chalcones | Q32061406 | ||
| Biosynthesis of complex polyketides in a metabolically engineered strain of E. coli | Q32075037 | ||
| The putative elaiophylin biosynthetic gene cluster in Streptomyces sp. DSM4137 is adjacent to genes encoding adenosylcobalamin-dependent methylmalonyl CoA mutase and to genes for synthesis of cobalamin | Q33207034 | ||
| The gene cluster for fluorometabolite biosynthesis in Streptomyces cattleya: a thioesterase confers resistance to fluoroacetyl-coenzyme A. | Q33244396 | ||
| Organization of the biosynthetic gene cluster for the macrolide antibiotic spiramycin in Streptomyces ambofaciens | Q33307918 | ||
| Insights into the biosynthesis of the benzoquinone ansamycins geldanamycin and herbimycin, obtained by gene sequencing and disruption | Q33913477 | ||
| Glycopeptide antibiotic biosynthesis: enzymatic assembly of the dedicated amino acid monomer (S)-3,5-dihydroxyphenylglycine | Q33952741 | ||
| Role of an essential acyl coenzyme A carboxylase in the primary and secondary metabolism of Streptomyces coelicolor A3(2). | Q33990283 | ||
| Role of crotonyl coenzyme A reductase in determining the ratio of polyketides monensin A and monensin B produced by Streptomyces cinnamonensis | Q33993141 | ||
| Crystal structures of Salinosporamide A (NPI-0052) and B (NPI-0047) in complex with the 20S proteasome reveal important consequences of beta-lactone ring opening and a mechanism for irreversible binding | Q33994984 | ||
| MeaA, a putative coenzyme B12-dependent mutase, provides methylmalonyl coenzyme A for monensin biosynthesis in Streptomyces cinnamonensis. | Q33995834 | ||
| Malonate metabolism: biochemistry, molecular biology, physiology, and industrial application | Q34152639 | ||
| Type I polyketide biosynthesis in bacteria (Part A--erythromycin biosynthesis). | Q34240567 | ||
| Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model | Q34267723 | ||
| Polyketide biosynthesis: a millennium review | Q34362914 | ||
| Purification of crotonyl-CoA reductase from Streptomyces collinus and cloning, sequencing and expression of the corresponding gene in Escherichia coli. | Q34367231 | ||
| Identification and characterization of the niddamycin polyketide synthase genes from Streptomyces caelestis | Q34448705 | ||
| A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib | Q34467271 | ||
| A gene cluster encoding malonyl-CoA decarboxylase (MatA), malonyl-CoA synthetase (MatB) and a putative dicarboxylate carrier protein (MatC) in Rhizobium trifolii--cloning, sequencing, and expression of the enzymes in Escherichia coli | Q34481085 | ||
| Nature's inventory of halogenation catalysts: oxidative strategies predominate | Q34555225 | ||
| Biosynthesis and attachment of novel bacterial polyketide synthase starter units | Q34569823 | ||
| Biosynthetic convergence of salinosporamides A and B in the marine actinomycete Salinispora tropica | Q34609001 | ||
| Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning of the tautomycin biosynthetic gene cluster from Streptomyces spiroverticillatus | Q34696900 | ||
| Utilization of the methoxymalonyl-acyl carrier protein biosynthesis locus for cloning the oxazolomycin biosynthetic gene cluster from Streptomyces albus JA3453 | Q34696963 | ||
| Multi-subunit acetyl-CoA carboxylases | Q34744707 | ||
| Hydroxymalonyl-acyl carrier protein (ACP) and aminomalonyl-ACP are two additional type I polyketide synthase extender units | Q35080629 | ||
| Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms | Q35114475 | ||
| Engineering of primary carbohydrate metabolism for increased production of actinorhodin in Streptomyces coelicolor | Q35129974 | ||
| A novel alternate anaplerotic pathway to the glyoxylate cycle in streptomycetes | Q35628145 | ||
| Source of methylmalonyl-coenzyme A for erythromycin synthesis: methylmalonyl-coenzyme A mutase from Streptomyces erythreus | Q35756779 | ||
| Loss of co-linearity by modular polyketide synthases: a mechanism for the evolution of chemical diversity | Q35906148 | ||
| Amino acid catabolism and antibiotic synthesis: valine is a source of precursors for macrolide biosynthesis in Streptomyces ambofaciens and Streptomyces fradiae | Q35976262 | ||
| Biological activities of two fungistatic antibiotics produced by Bacillus cereus UW85 | Q36056183 | ||
| Cloning and expression of daunorubicin biosynthesis genes from Streptomyces peucetius and S. peucetius subsp. caesius | Q36165429 | ||
| Mechanisms for incorporation of glycerol-derived precursors into polyketide metabolites | Q36269257 | ||
| Isolation and characterization of acyl coenzyme A carboxylases from Mycobacterium tuberculosis and Mycobacterium bovis, which produce multiple methyl-branched mycocerosic acids. | Q36388429 | ||
| Chemoenzymatic and template-directed synthesis of bioactive macrocyclic peptides | Q36416681 | ||
| Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering | Q36485566 | ||
| The type I fatty acid and polyketide synthases: a tale of two megasynthases | Q36489362 | ||
| Type II polyketide synthases: gaining a deeper insight into enzymatic teamwork | Q36724719 | ||
| Versatile polyketide enzymatic machinery for the biosynthesis of complex mycobacterial lipids. | Q36772380 | ||
| Elucidation of the kijanimicin gene cluster: insights into the biosynthesis of spirotetronate antibiotics and nitrosugars | Q36835457 | ||
| Identification of residues essential for a two-step reaction by malonyl-CoA synthetase from Rhizobium trifolii | Q38318843 | ||
| Erythromycin production in Saccharopolyspora erythraea does not require a functional propionyl-CoA carboxylase | Q38360818 | ||
| Insertional inactivation of methylmalonyl coenzyme A (CoA) mutase and isobutyryl-CoA mutase genes in Streptomyces cinnamonensis: influence on polyketide antibiotic biosynthesis. | Q39497386 | ||
| Mutasynthesis of fluorosalinosporamide, a potent and reversible inhibitor of the proteasome | Q39992589 | ||
| Type III polyketide synthase beta-ketoacyl-ACP starter unit and ethylmalonyl-CoA extender unit selectivity discovered by Streptomyces coelicolor genome mining | Q40179764 | ||
| Mode of action of the microbial metabolite GE23077, a novel potent and selective inhibitor of bacterial RNA polymerase | Q40494671 | ||
| Biosynthesis of monensin | Q41029991 | ||
| Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea | Q42611970 | ||
| Analysis of four tylosin biosynthetic genes from the tylLM region of the Streptomyces fradiae genome | Q42649623 | ||
| Analysis of the tetronomycin gene cluster: insights into the biosynthesis of a polyether tetronate antibiotic | Q42651638 | ||
| Characterization of the biosynthetic gene cluster for the antifungal polyketide soraphen A from Sorangium cellulosum So ce26. | Q42677431 | ||
| Kinetic and structural analysis of a new group of Acyl-CoA carboxylases found in Streptomyces coelicolor A3(2). | Q42677759 | ||
| Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis. | Q42689234 | ||
| Characterization of acetyl-CoA/propionyl-CoA carboxylase in Metallosphaera sedula. Carboxylating enzyme in the 3-hydroxypropionate cycle for autotrophic carbon fixation. | Q43032436 | ||
| 4-[2-(2-amino-2-oxoethyl)-2,7-dihydroxy-4-oxochroman-5-yl]-3-hydroxybut-2-enoic acid | Q43394722 | ||
| Enhancing the atom economy of polyketide biosynthetic processes through metabolic engineering. | Q43695714 | ||
| Analysis of the prodiginine biosynthesis gene cluster of Streptomyces coelicolor A3(2): new mechanisms for chain initiation and termination in modular multienzymes | Q43713841 | ||
| Production of ansamycin polyketide precursors in Escherichia coli | Q43718451 | ||
| A new substrate specificity for acyl transferase domains of the ascomycin polyketide synthase in Streptomyces hygroscopicus. | Q43851405 | ||
| Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis | Q43963848 | ||
| Screening for biologically active metabolites with endosymbiotic bacilli isolated from arthropods | Q44247563 | ||
| Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602. | Q44314986 | ||
| Incorporation of acetate, propionate, and methionine into rapamycin by Streptomyces hygroscopicus | Q44453248 | ||
| Biosynthetic studies using carbon-13 enriched precursors on the 16-membered macrolide antibiotic leucomycin A3 | Q44610746 | ||
| Crotonyl-coenzyme A reductase provides methylmalonyl-CoA precursors for monensin biosynthesis by Streptomyces cinnamonensis in an oil-based extended fermentation | Q44905579 | ||
| Multiple pathways for acetate assimilation in Streptomyces cinnamonensis | Q44913854 | ||
| Identification and disruptional analysis of the Streptomyces cinnamonensis msdA gene, encoding methylmalonic acid semialdehyde dehydrogenase | Q44915081 | ||
| Engineered biosynthesis of 16-membered macrolides that require methoxymalonyl-ACP precursors in Streptomyces fradiae | Q44923152 | ||
| Biosynthetic investigations of the V-type ATPase inhibitors bafilomycin A1, B1 and concanamycin A. | Q45215516 | ||
| Biochemical characterization of the minimal polyketide synthase domains in the lovastatin nonaketide synthase LovB. | Q46337180 | ||
| Glyceryl-S-acyl carrier protein as an intermediate in the biosynthesis of tetronate antibiotics | Q46875948 | ||
| The leptomycin gene cluster and its heterologous expression in Streptomyces lividans | Q46879161 | ||
| Metabolic pathway engineering for complex polyketide biosynthesis in Saccharomyces cerevisiae. | Q46901236 | ||
| P433 | issue | 1 | |
| P304 | page(s) | 90-114 | |
| P577 | publication date | 2009-01-01 | |
| P1433 | published in | Natural Product Reports | Q2376904 |
| P1476 | title | Biosynthesis of polyketide synthase extender units | |
| P478 | volume | 26 |
| Q82605455 | A novel docking domain interface model predicting recombination between homoeologous modular biosynthetic gene clusters |
| Q35360872 | A polyketide synthase acyltransferase domain structure suggests a recognition mechanism for its hydroxymalonyl-acyl carrier protein substrate |
| Q35006338 | A sea of biosynthesis: marine natural products meet the molecular age. |
| Q57437942 | Abiotic formation of uroporphyrinogen and coproporphyrinogen from acyclic reactants |
| Q64897732 | Acyltransferases as Tools for Polyketide Synthase Engineering. |
| Q41086288 | An acyltransferase domain of FK506 polyketide synthase recognizing both an acyl carrier protein and coenzyme A as acyl donors to transfer allylmalonyl and ethylmalonyl units |
| Q54283066 | An unusual dehydratase acting on glycerate and a ketoreducatse stereoselectively reducing α-ketone in polyketide starter unit biosynthesis. |
| Q42615534 | Analysis of the indanomycin biosynthetic gene cluster from Streptomyces antibioticus NRRL 8167. |
| Q37962381 | Beyond ethylmalonyl-CoA: the functional role of crotonyl-CoA carboxylase/reductase homologs in expanding polyketide diversity |
| Q52560616 | Biosynthesis and evolution of coronafacoyl phytotoxin production in the common scab pathogen Streptomyces scabies. |
| Q64916664 | Biosynthesis of Polyketides in Streptomyces. |
| Q55380490 | Biosynthesis of Rishirilide B. |
| Q52647572 | Biosynthesis of hygrocins, antitumor naphthoquinone ansamycins produced by Streptomyces sp. LZ35. |
| Q46913126 | Biosynthesis of phenylnannolone A, a multidrug resistance reversal agent from the halotolerant myxobacterium Nannocystis pusilla B150. |
| Q37768655 | Biosynthesis of rapamycin and its regulation: past achievements and recent progress |
| Q37331323 | Biosynthesis of salinosporamides from alpha,beta-unsaturated fatty acids: implications for extending polyketide synthase diversity. |
| Q34538163 | Biosynthesis of the allylmalonyl-CoA extender unit for the FK506 polyketide synthase proceeds through a dedicated polyketide synthase and facilitates the mutasynthesis of analogues. |
| Q37282449 | Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine |
| Q37946335 | Carboxylases in natural and synthetic microbial pathways |
| Q44152357 | Characterization and engineering of the ethylmalonyl-CoA pathway towards the improved heterologous production of polyketides in Streptomyces venezuelae |
| Q54359411 | Characterization of 2-octenoyl-CoA carboxylase/reductase utilizing pteB from Streptomyce avermitilis. |
| Q59771356 | Cheminformatics-based enumeration and analysis of large libraries of macrolide scaffolds |
| Q33847732 | Cloning of separate meilingmycin biosynthesis gene clusters by use of acyltransferase-ketoreductase didomain PCR amplification |
| Q48059428 | Cloning, sequencing and characterization of the biosynthetic gene cluster of sanglifehrin A, a potent cyclophilin inhibitor. |
| Q33510811 | Clustering of protein domains for functional and evolutionary studies |
| Q64018794 | Comparative Transcriptome Analysis Shows Conserved Metabolic Regulation during Production of Secondary Metabolites in Filamentous Fungi |
| Q46828034 | Comparative metabolic profiling-based improvement of rapamycin production by Streptomyces hygroscopicus |
| Q38745850 | Complete elucidation of the late steps of bafilomycin biosynthesis in Streptomyces lohii. |
| Q27000500 | Complexity generation during natural product biosynthesis using redox enzymes |
| Q50907566 | Controlling the feed rate of propanol to optimize erythromycin fermentation by on-line capacitance and oxygen uptake rate measurement. |
| Q37028302 | Designed biosynthesis of 36-methyl-FK506 by polyketide precursor pathway engineering. |
| Q90417487 | Development of a cyanobacterial heterologous polyketide production platform |
| Q90365236 | Discovery of 16-Demethylrifamycins by Removing the Predominant Polyketide Biosynthesis Pathway in Micromonospora sp. Strain TP-A0468 |
| Q61774178 | Divergolides A-D from a Mangrove Endophyte Reveal an Unparalleled Plasticity in ansa-Macrolide Biosynthesis |
| Q90380911 | Diversification of polyketide structures via synthase engineering |
| Q40577171 | Draft genome sequence of Streptomyces sp. TP-A0882 reveals putative butyrolactol biosynthetic pathway |
| Q47215208 | Engineered polyketides: Synergy between protein and host level engineering. |
| Q40753302 | Engineering microbial cells for the biosynthesis of natural compounds of pharmaceutical significance |
| Q38806940 | Engineering microbial hosts for production of bacterial natural products |
| Q59800881 | Engineering of the Filamentous Fungus as Cell Factory for Natural Products |
| Q34739957 | Engineering polyketide synthases and nonribosomal peptide synthetases |
| Q37677554 | Engineering the acyltransferase substrate specificity of assembly line polyketide synthases |
| Q43276111 | Enhanced FK506 production in Streptomyces clavuligerus CKD1119 by engineering the supply of methylmalonyl-CoA precursor |
| Q50528502 | Enhanced salinomycin production by adjusting the supply of polyketide extender units in Streptomyces albus. |
| Q50910710 | Enhancement of UDPG synthetic pathway improves ansamitocin production in Actinosynnem pretiosum. |
| Q41741898 | Enzymatic polyketide chain branching to give substituted lactone, lactam, and glutarimide heterocycles |
| Q33753331 | Expanding the fluorine chemistry of living systems using engineered polyketide synthase pathways. |
| Q34407592 | Exploring the potential of endophytes from medicinal plants as sources of antimycobacterial compounds |
| Q51607914 | Extending Polyketide Structural Diversity by Using Engineered Carboxylase/Reductase Enzymes. |
| Q37282901 | First biosynthetic pathway of 1-hepten-3-one in Iporangaia pustulosa (Opiliones) |
| Q33429442 | Formation and characterization of acyl carrier protein-linked polyketide synthase extender units |
| Q33447958 | Genome-wide Screening Reveals the Genetic Determinants of an Antibiotic Insecticide in Bacillus thuringiensis |
| Q64077158 | Genomic Characterization and Virulence Potential of Two Fusarium oxysporum Isolates Cultured from the International Space Station |
| Q55501475 | Genomic Insight into Symbiosis-Induced Insect Color Change by a Facultative Bacterial Endosymbiont, "Candidatus Rickettsiella viridis". |
| Q36578763 | Harnessing natural product assembly lines: structure, promiscuity, and engineering |
| Q38423236 | Herboxidiene biosynthesis, production, and structural modifications: prospect for hybrids with related polyketide |
| Q36001262 | Hijacking a hydroxyethyl unit from a central metabolic ketose into a nonribosomal peptide assembly line |
| Q44420274 | Identification and characterization of the cuevaene A biosynthetic gene cluster in streptomyces sp. LZ35. |
| Q54231284 | Identification and heterologous expression of the actinoallolide biosynthetic gene cluster. |
| Q34173936 | Identification of a bioactive 51-membered macrolide complex by activation of a silent polyketide synthase in Streptomyces ambofaciens |
| Q34293664 | Identification of the biosynthetic gene cluster for the antibiotic polyketide L-155,175 in Streptomyces hygroscopicus |
| Q42612717 | Identification of the incednine biosynthetic gene cluster: characterization of novel β-glutamate-β-decarboxylase IdnL3. |
| Q38628326 | Iterative polyketide biosynthesis by modular polyketide synthases in bacteria |
| Q92702305 | Leveraging synthetic biology for producing bioactive polyketides and non-ribosomal peptides in bacterial heterologous hosts |
| Q39114871 | Limitations of the 'ambush hypothesis' at the single-gene scale: what codon biases are to blame? |
| Q89157340 | Loading of malonyl-CoA onto tandem acyl carrier protein domains of polyunsaturated fatty acid synthases |
| Q35844928 | Metabolic Interplay between the Asian Citrus Psyllid and Its Profftella Symbiont: An Achilles' Heel of the Citrus Greening Insect Vector |
| Q39165584 | Mining Bacterial Genomes for Secondary Metabolite Gene Clusters. |
| Q24622078 | Molecular insights into the biosynthesis of guadinomine: a type III secretion system inhibitor |
| Q42716635 | Multi-factorial engineering of heterologous polyketide production in Escherichia coli reveals complex pathway interactions. |
| Q44866313 | Mutant malonyl-CoA synthetases with altered specificity for polyketide synthase extender unit generation |
| Q34096062 | Natural products version 2.0: connecting genes to molecules. |
| Q52562784 | Novel Type III Polyketide Synthases Biosynthesize Methylated Polyketides in Mycobacterium marinum. |
| Q47136344 | Only Acyl Carrier Protein 1 (AcpP1) Functions in Pseudomonas aeruginosa Fatty Acid Synthesis |
| Q58904697 | Pirin: A novel redox-sensitive modulator of primary and secondary metabolism in Streptomyces |
| Q37672851 | Polyketide stereocontrol: a study in chemical biology |
| Q36378877 | Primordial oil slick and the formation of hydrophobic tetrapyrrole macrocycles |
| Q88013414 | Production of pikromycin using branched chain amino acid catabolism in Streptomyces venezuelae ATCC 15439 |
| Q35826557 | Production of the Bengamide Class of Marine Natural Products in Myxobacteria: Biosynthesis and Structure-Activity Relationships. |
| Q34107140 | Programming of erythromycin biosynthesis by a modular polyketide synthase |
| Q39417729 | Promiscuity of a modular polyketide synthase towards natural and non-natural extender units. |
| Q37946763 | Protein engineering towards natural product synthesis and diversification |
| Q27702125 | Rational Control of Polyketide Extender Units by Structure-Based Engineering of a Crotonyl-CoA Carboxylase/Reductase in Antimycin Biosynthesis |
| Q38936310 | Recent advances in engineering propionyl-CoA metabolism for microbial production of value-added chemicals and biofuels |
| Q38264066 | Recent advances in the biosynthesis of unusual polyketide synthase substrates |
| Q33547618 | Recognition of (2S)-aminomalonyl-acyl carrier protein (ACP) and (2R)-hydroxymalonyl-ACP by acyltransferases in zwittermicin A biosynthesis |
| Q41881191 | Reconstitution of the FK228 biosynthetic pathway reveals cross talk between modular polyketide synthases and fatty acid synthase |
| Q89805917 | Regulatory Patterns of Crp on Monensin Biosynthesis in Streptomyces cinnamonensis |
| Q96155794 | Repurposing Modular Polyketide Synthases and Non-ribosomal Peptide Synthetases for Novel Chemical Biosynthesis |
| Q35780235 | Screening and Engineering the Synthetic Potential of Carboxylating Reductases from Central Metabolism and Polyketide Biosynthesis. |
| Q44877354 | Simple formation of an abiotic porphyrinogen in aqueous solution. |
| Q44110767 | Simultaneous production and partitioning of heterologous polyketide and isoprenoid natural products in an Escherichia coli two-phase bioprocess |
| Q48270878 | Six Trikentrin-like Cyclopentanoindoles from Trikentrion flabelliforme. Absolute Structural Assignment by NMR and ECD. |
| Q38264057 | Stereocontrol within polyketide assembly lines |
| Q37352218 | Structural analysis of protein-protein interactions in type I polyketide synthases |
| Q78310484 | Structure revision of trichotoxin, a chlorinated polyketide isolated from a Trichodesmium thiebautii bloom |
| Q27670675 | Structure-Guided Expansion of the Substrate Range of Methylmalonyl Coenzyme A Synthetase (MatB) of Rhodopseudomonas palustris |
| Q36607621 | Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis. |
| Q37973514 | Synthetic biological approaches to natural product biosynthesis |
| Q44144019 | The AT₂ domain of KirCI loads malonyl extender units to the ACPs of the kirromycin PKS. |
| Q38922927 | The Enzymology of Organic Transformations: A Survey of Name Reactions in Biological Systems. |
| Q39231472 | The Uncommon Enzymology of Cis-Acyltransferase Assembly Lines |
| Q38581311 | The biosynthetic pathway of FK506 and its engineering: from past achievements to future prospects |
| Q52684313 | The chejuenolide biosynthetic gene cluster harboring an iterative trans-AT PKS system in Hahella chejuensis strain MB-1084. |
| Q47196211 | The coronafacoyl phytotoxins: structure, biosynthesis, regulation and biological activities. |
| Q51709407 | The glucose RQ-feedback control leading to improved erythromycin production by a recombinant strain Saccharopolyspora erythraea ZL1004 and its scale-up to 372-m(3) fermenter. |
| Q28483853 | The insect pathogen Serratia marcescens Db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin |
| Q41212729 | Twofold polyketide branching by a stereoselective enzymatic Michael addition |
| Q41728531 | Using surrogates to bypass missing catalytic components |
| Q48165004 | Warhead biosynthesis and the origin of structural diversity in hydroxamate metalloproteinase inhibitors. |
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