| scholarly article | Q13442814 |
| P50 | author | Anders Goksøyr | Q17064580 |
| Roger Lille-Langøy | Q59664522 | ||
| Malin C Celander | Q64212382 | ||
| John J. Stegeman | Q109774481 | ||
| Jared V. Goldstone | Q37643741 | ||
| Mark E. Hahn | Q37643930 | ||
| P2093 | author name string | Akira Kubota | |
| Sibel I Karchner | |||
| Afonso C D Bainy | |||
| P2860 | cites work | SXR, a novel steroid and xenobiotic-sensing nuclear receptor | Q22003995 |
| The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions | Q24310512 | ||
| Genenames.org: the HGNC resources in 2013 | Q24595108 | ||
| Genetic predictors of interindividual variability in hepatic CYP3A4 expression | Q24631001 | ||
| Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors). | Q24815571 | ||
| Unexpected novel relational links uncovered by extensive developmental profiling of nuclear receptor expression | Q27314765 | ||
| The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity | Q27632611 | ||
| Construction and characterization of a fully active PXR/SRC-1 tethered protein with increased stability | Q27650531 | ||
| Clustal W and Clustal X version 2.0 | Q27860517 | ||
| A general empirical model of protein evolution derived from multiple protein families using a maximum-likelihood approach | Q27860716 | ||
| RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models | Q27860746 | ||
| MEGA5: Molecular Evolutionary Genetics Analysis Using Maximum Likelihood, Evolutionary Distance, and Maximum Parsimony Methods | Q27860929 | ||
| The human pregnane X receptor: genomic structure and identification and functional characterization of natural allelic variants | Q28201500 | ||
| The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism | Q28206406 | ||
| An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathway | Q28263744 | ||
| PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators | Q28281902 | ||
| Activation of mammalian retinoid X receptors by the insect growth regulator methoprene | Q28367841 | ||
| The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution | Q28378587 | ||
| Evolution of the pregnane x receptor: adaptation to cross-species differences in biliary bile salts | Q28755660 | ||
| Assumption-free analysis of quantitative real-time polymerase chain reaction (PCR) data | Q29616220 | ||
| Mutation nomenclature extensions and suggestions to describe complex mutations: a discussion | Q29616531 | ||
| Novel single nucleotide polymorphisms in the promoter and intron 1 of human pregnane X receptor/NR1I2 and their association with CYP3A4 expression | Q42519981 | ||
| Regulation of zebrafish CYP3A65 transcription by AHR2. | Q42711641 | ||
| Activation of a tunicate (Ciona intestinalis) xenobiotic receptor orthologue by both natural toxins and synthetic toxicants | Q42722651 | ||
| Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors | Q43974257 | ||
| Benzoate X receptors alpha and beta are pharmacologically distinct and do not function as xenobiotic receptors | Q44116143 | ||
| Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier | Q45025187 | ||
| A structural basis for constitutive activity in the human CAR/RXRalpha heterodimer | Q45195405 | ||
| Update on allele nomenclature for human cytochromes P450 and the Human Cytochrome P450 Allele (CYP-allele) Nomenclature Database | Q45561380 | ||
| Expression of PXR, CYP3A and MDR1 genes in liver of zebrafish | Q46507872 | ||
| Constitutive and xenobiotics-induced expression of a novel CYP3A gene from zebrafish larva | Q46515187 | ||
| A comparison of hepatic P450 induction in rat and trout (Oncorhynchus mykiss): delineation of the site of resistance of fish to phenobarbital-type inducers | Q46915377 | ||
| The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease | Q46939911 | ||
| Evolutionary genomics of nuclear receptors: from twenty-five ancestral genes to derived endocrine systems | Q47259714 | ||
| Proposal for an allele nomenclature system based on the evolutionary divergence of haplotypes | Q48727753 | ||
| Nomenclature for the description of human sequence variations | Q48738393 | ||
| Recommendations for a nomenclature system for human gene mutations. Nomenclature Working Group | Q48771295 | ||
| Expression and activity of p-glycoprotein elevated by dexamethasone in cultured retinal pigment epithelium involve glucocorticoid receptor and pregnane X receptor. | Q54310936 | ||
| Further consideration of phenobarbital effects on cytochrome P-450 activity in the killifish, Fundulus Heteroclitus | Q59848683 | ||
| Species characteristics of the hepatic xenobiotic and steroid biotransformation systems of two teleost fish, Atlantic cod (Gadus morhua) and rainbow trout (Salmo gairdneri) | Q68823742 | ||
| Absence of hepatic microsomal pentyl- or benzyl-resorufin O-dealkylase induction in rainbow trout (Salmo gairdneri) treated with phenobarbitone | Q68983125 | ||
| Rat pregnane X receptor: molecular cloning, tissue distribution, and xenobiotic regulation | Q78025580 | ||
| CDD: conserved domains and protein three-dimensional structure | Q30424248 | ||
| Evolution of pharmacologic specificity in the pregnane X receptor | Q33326759 | ||
| Amplification efficiency: linking baseline and bias in the analysis of quantitative PCR data | Q33411668 | ||
| Evolutionary history and functional characterization of the amphibian xenosensor CAR. | Q33636734 | ||
| P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR. | Q33720425 | ||
| The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species. | Q33811323 | ||
| Two panels of steroid receptor luciferase reporter cell lines for compound profiling. | Q33837335 | ||
| Use of the nuclear receptor PXR to predict drug interactions | Q34088796 | ||
| Population pharmacokinetic modeling of the association between 63396C->T pregnane X receptor polymorphism and unboosted atazanavir clearance | Q34309475 | ||
| Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor | Q34467451 | ||
| Polymorphisms in NF-κB, PXR, LXR, PPARγ and risk of inflammatory bowel disease | Q34487187 | ||
| Evolution of promiscuous nuclear hormone receptors: LXR, FXR, VDR, PXR, and CAR | Q34550999 | ||
| Functional and structural comparison of PXR and CAR. | Q35062476 | ||
| Dissection of organs from the adult zebrafish | Q35130644 | ||
| CAR and PXR: the xenobiotic-sensing receptors | Q35944704 | ||
| Opposing regulation of cytochrome P450 expression by CAR and PXR in hypothyroid mice | Q36103384 | ||
| CAR and PXR: xenosensors of endocrine disrupters? | Q36212927 | ||
| A comprehensive in vitro and in silico analysis of antibiotics that activate pregnane X receptor and induce CYP3A4 in liver and intestine | Q36331220 | ||
| Pharmacogenomics of Cytochrome P450 3A4: Recent Progress Toward the "Missing Heritability" Problem | Q36634077 | ||
| Role of CAR and PXR in xenobiotic sensing and metabolism | Q36672089 | ||
| Activation of steroid and xenobiotic receptor (SXR, NR1I2) and its orthologs in laboratory, toxicologic, and genome model species | Q36755546 | ||
| Identification of polymorphisms in the 3'-untranslated region of the human pregnane X receptor (PXR) gene associated with variability in cytochrome P450 3A (CYP3A) metabolism | Q37207247 | ||
| Molecular cloning, characterization, and evolutionary analysis of estrogen receptors from phylogenetically ancient fish | Q37325292 | ||
| The cytochrome P450 2AA gene cluster in zebrafish (Danio rerio): expression of CYP2AA1 and CYP2AA2 and response to phenobarbital-type inducers | Q37355755 | ||
| The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism | Q37400616 | ||
| Interactions of pharmaceuticals and other xenobiotics on hepatic pregnane X receptor and cytochrome P450 3A signaling pathway in rainbow trout (Oncorhynchus mykiss). | Q39666096 | ||
| Regulation of CYP3A4 by pregnane X receptor: The role of nuclear receptors competing for response element binding | Q39737247 | ||
| Compound profiling using a panel of steroid hormone receptor cell-based assays | Q39946315 | ||
| The orphan human pregnane X receptor mediates the transcriptional activation of CYP3A4 by rifampicin through a distal enhancer module | Q40916686 | ||
| Metabolism of alkoxyphenoxazones by channel catfish liver microsomes: effects of phenobarbital, Aroclor 1254 and 3-methylcholanthrene | Q41863802 | ||
| Improved dual-luciferase reporter assays for nuclear receptors | Q42235596 | ||
| Natural protein variants of pregnane X receptor with altered transactivation activity toward CYP3A4. | Q42511482 | ||
| The role of residues T248, Y249 and T422 in the function of human pregnane X receptor | Q42512684 | ||
| Role of AHR2 in the expression of novel cytochrome P450 1 family genes, cell cycle genes, and morphological defects in developing zebra fish exposed to 3,3',4,4',5-pentachlorobiphenyl or 2,3,7,8-tetrachlorodibenzo-p-dioxin | Q42517288 | ||
| P921 | main subject | Danio rerio | Q169444 |
| P304 | page(s) | 447-457 | |
| P577 | publication date | 2013-09-20 | |
| P1433 | published in | Aquatic Toxicology | Q4782796 |
| P1476 | title | Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio) | |
| P478 | volume | 142-143 |
| Q98217010 | Assessing species-specific differences for nuclear receptor activation for environmental water extracts |
| Q38932500 | BFCOD activity in fish cell lines and zebrafish embryos and its modulation by chemical ligands of human aryl hydrocarbon and nuclear receptors. |
| Q33835410 | Development of a common carp (Cyprinus carpio) pregnane X receptor (cPXR) transactivation reporter assay and its activation by azole fungicides and pharmaceutical chemicals. |
| Q49572693 | Endocrine disruption and differential gene expression in sentinel fish on St. Lawrence Island, Alaska: Health implications for indigenous residents. |
| Q64958249 | Evolutionary Plasticity in Detoxification Gene Modules: The Preservation and Loss of the Pregnane X Receptor in Chondrichthyes Lineages. |
| Q44856350 | In response: conservation versus functional diversification of nuclear receptors: an academic perspective |
| Q27022545 | Marine invertebrate xenobiotic-activated nuclear receptors: their application as sensor elements in high-throughput bioassays for marine bioactive compounds |
| Q35086241 | Metformin exposure at environmentally relevant concentrations causes potential endocrine disruption in adult male fish |
| Q35029560 | Regulation of pregnane-X-receptor, CYP3A and P-glycoprotein genes in the PCB-resistant killifish (Fundulus heteroclitus) population from New Bedford Harbor |
| Q35014430 | Role of pregnane X receptor and aryl hydrocarbon receptor in transcriptional regulation of pxr, CYP2, and CYP3 genes in developing zebrafish |
| Q58107759 | Sequence variations in pxr (nr1i2) from zebrafish (Danio rerio) strains affect nuclear receptor function |
| Q38300335 | Zebrafish vitamin K epoxide reductases: expression in vivo, along extracellular matrix mineralization and under phylloquinone and warfarin in vitro exposure. |
Search more.