Evolutionary Plasticity in Detoxification Gene Modules: The Preservation and Loss of the Pregnane X Receptor in Chondrichthyes Lineages.

scientific article published on 10 May 2019

Evolutionary Plasticity in Detoxification Gene Modules: The Preservation and Loss of the Pregnane X Receptor in Chondrichthyes Lineages. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3390/IJMS20092331
P953full work available at URLhttps://www.mdpi.com/1422-0067/20/9/2331
P932PMC publication ID6539745
P698PubMed publication ID31083458

P50authorAndré M. MachadoQ62572590
Luís Filipe C CastroQ41526444
Raquel RuivoQ46361967
Elza FonsecaQ58325362
P2093author name stringMiguel M Santos
Boon-Hui Tay
Raquel Ruivo
Byrappa Venkatesh
André M. Machado
L. Filipe C. Castro
Miguel M. Santos
Elza S. S. Fonseca
Francisca Conrado
P2860cites workThe evolutionary exploitation of vertebrate peroxisome proliferator-activated receptor γ by organotinsQ58606671
Independent losses of a xenobiotic receptor across teleost evolutionQ64212106
Estrogen suppression of connective tissue deposition in a murine model of peritoneal adhesion formationQ71020355
Epidermal overexpression of xenobiotic receptor PXR impairs the epidermal barrier and triggers Th2 immune response.Q42515415
A mollusk VDR/PXR/CAR-like (NR1J) nuclear receptor provides insight into ancient detoxification mechanismsQ42699377
Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptorsQ43974257
Evolutionary genomics of nuclear receptors: from twenty-five ancestral genes to derived endocrine systemsQ47259714
The Divergent Genomes of TeleostsQ49976429
Identifying the gaps: Resources and perspectives on the use of nuclear receptor based-assays to improve hazard assessment of emerging contaminants.Q53283866
A biologist's guide to Bayesian phylogenetic analysis.Q54339947
Shark genomes provide insights into elasmobranch evolution and the origin of vertebratesQ57295515
The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactionsQ24310512
The chemical defensome: environmental sensing and response genes in the Strongylocentrotus purpuratus genomeQ24605756
Evolutionary selection across the nuclear hormone receptor superfamily with a focus on the NR1I subfamily (vitamin D, pregnane X, and constitutive androstane receptors).Q24815571
Role of pregnane X receptor in chemotherapeutic treatmentQ26827398
Anatomical profiling of nuclear receptor expression reveals a hierarchical transcriptional networkQ28259101
An orphan nuclear receptor activated by pregnanes defines a novel steroid signaling pathwayQ28263744
Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligandsQ28375193
Molecular cloning, functional characterization, and evolutionary analysis of vitamin D receptors isolated from basal vertebratesQ28649913
SkateBase, an elasmobranch genome project and collection of molecular resources for chondrichthyan fishesQ28655064
Elephant shark genome provides unique insights into gnathostome evolutionQ28660739
Evolution of the pregnane x receptor: adaptation to cross-species differences in biliary bile saltsQ28755660
Parallelization of the MAFFT multiple sequence alignment programQ33567535
Evolutionary history and functional characterization of the amphibian xenosensor CAR.Q33636734
Regulation of drug-metabolizing enzymes by xenobiotic receptors: PXR and CARQ34349336
Estrogen and skin. An overviewQ34435860
Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptorQ34467451
Families of nuclear receptors in vertebrate models: characteristic and comparative toxicological perspectiveQ35119512
A RESTful API for Access to Phylogenetic Tools via the CIPRES Science Gateway.Q35185792
Environmental contaminants activate human and polar bear (Ursus maritimus) pregnane X receptors (PXR, NR1I2) differentlyQ35288427
A natural deletion of the HoxC cluster in elasmobranch fishesQ35689831
Bisphenol A and its analogues activate human pregnane X receptorQ35807873
Activation of steroid and xenobiotic receptor (SXR, NR1I2) and its orthologs in laboratory, toxicologic, and genome model speciesQ36755546
CXR, a chicken xenobiotic-sensing orphan nuclear receptor, is related to both mammalian pregnane X receptor (PXR) and constitutive androstane receptor (CAR)Q37259679
Functional characterization of a full length pregnane X receptor, expression in vivo, and identification of PXR alleles, in zebrafish (Danio rerio)Q37416172
Nuclear receptors CAR and PXR: Molecular, functional, and biomedical aspectsQ37475474
LXRα and LXRβ Nuclear Receptors Evolved in the Common Ancestor of GnathostomesQ37738638
Role of PPAR, LXR, and PXR in epidermal homeostasis and inflammation.Q38169441
Draft sequencing and assembly of the genome of the world's largest fish, the whale shark: Rhincodon typus Smith 1828Q38373150
Genome-wide identification of nuclear receptor (NR) genes and the evolutionary significance of the NR1O subfamily in the monogonont rotifer Brachionus spp.Q38695680
In vivo responses of the human and murine pregnane X receptor to dexamethasone in miceQ39720830
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectChondrichthyesQ25371
P304page(s)2331
P577publication date2019-01-01
2019-05-10
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleEvolutionary Plasticity in Detoxification Gene Modules: The Preservation and Loss of the Pregnane X Receptor in Chondrichthyes Lineages
Evolutionary Plasticity in Detoxification Gene Modules: The Preservation and Loss of the Pregnane X Receptor in Chondrichthyes Lineages.
P478volume20