Evaluation of a novel macromolecular cascade-polymer contrast medium for dynamic contrast-enhanced MRI monitoring of antiangiogenic bevacizumab therapy in a human melanoma model

scientific article published on October 2013

Evaluation of a novel macromolecular cascade-polymer contrast medium for dynamic contrast-enhanced MRI monitoring of antiangiogenic bevacizumab therapy in a human melanoma model is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.ACRA.2013.07.010
P932PMC publication ID3874547
P698PubMed publication ID24029057

P2093author name stringYanjun Fu
David M Shames
Michael F Wendland
Robert C Brasch
Clemens C Cyran
Bundit Chaopathomkul
Victor Rogut
P2860cites workGadolinium MRI contrast agents based on triazine dendrimers: relaxivity and in vivo pharmacokineticsQ30571992
Dendritic iodinated contrast agents with PEG-cores for CT imaging: synthesis and preliminary characterizationQ31049016
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Contrast-enhanced MR imaging of coronary arteries: comparison of intra- and extravascular contrast agents in swineQ32074895
Synthesis and evaluation of a polydisulfide with Gd-DOTA monoamide side chains as a biodegradable macromolecular contrast agent for MR blood pool imagingQ33768662
Macromolecular and dendrimer-based magnetic resonance contrast agentsQ34069230
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Permeability to macromolecular contrast media quantified by dynamic MRI correlates with tumor tissue assays of vascular endothelial growth factor (VEGF).Q35622504
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Benefit-risk assessment of bevacizumab in the treatment of breast cancer.Q37963955
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Tumor microvascular changes in antiangiogenic treatment: assessment by magnetic resonance contrast media of different molecular weights.Q40540980
Assessing tumor angiogenesis using macromolecular MR imaging contrast media.Q41352765
Dynamic contrast-enhanced magnetic resonance imaging rapidly indicates vessel regression in human squamous cell carcinomas grown in nude mice caused by VEGF receptor 2 blockade with DC101.Q41559635
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Albumin labeled with Gd-DTPA. An intravascular contrast-enhancing agent for magnetic resonance blood pool imaging: preparation and characterizationQ43962639
New macromolecular polymeric MRI contrast agents for application in the differentiation of cancer from benign soft tissues.Q45945812
Magnetic resonance imaging enhancement of normal tissues and tumors using macromolecular Gd-based cascade polymer contrast agents: preclinical evaluationsQ46090532
Quantification of tissue gadolinium concentration using magnetic resonance imaging: comparison of ultrashort inversion time inversion recovery echoplanar and dynamic three-dimensional spoiled gradient-recalled approaches with in vitro measurementsQ46319505
Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factorQ46319983
The choice of region of interest measures in contrast-enhanced magnetic resonance image characterization of experimental breast tumors.Q46423431
Perfusion MRI for Monitoring the Effect of Sorafenib on Experimental Prostate Carcinoma: A Validation StudyQ59689546
Simultaneous MRI measurement of blood flow, blood volume, and capillary permeability in mammary tumors using two different contrast agentsQ73266332
Steady-state and dynamic MR angiography with MS-325: initial experience in humansQ74521657
Phase II placebo-controlled randomized discontinuation trial of sorafenib in patients with metastatic renal cell carcinomaQ83195713
FDA pulls approval for avastin in breast cancerQ84133234
P433issue10
P921main subjectbevacizumabQ413299
angiogenesis inhibitorQ574834
macromoleculeQ178593
P304page(s)1256-1263
P577publication date2013-10-01
P1433published inAcademic RadiologyQ15755259
P1476titleEvaluation of a novel macromolecular cascade-polymer contrast medium for dynamic contrast-enhanced MRI monitoring of antiangiogenic bevacizumab therapy in a human melanoma model
P478volume20

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cites work (P2860)
Q2677481025 Years of Contrast-Enhanced MRI: Developments, Current Challenges and Future Perspectives
Q36750627Assessing vascular effects of adding bevacizumab to neoadjuvant chemotherapy in osteosarcoma using DCE-MRI.
Q39246340Contrast agents in dynamic contrast-enhanced magnetic resonance imaging
Q35867668Magnetic resonance-guided regional gene delivery strategy using a tumor stroma-permeable nanocarrier for pancreatic cancer

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