Benefit-risk assessment of bevacizumab in the treatment of breast cancer.

scientific article published on January 2012

Benefit-risk assessment of bevacizumab in the treatment of breast cancer. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1024688188
P356DOI10.2165/11595910-000000000-00000
P698PubMed publication ID22136182

P50authorFelipe AdesQ59158713
P2093author name stringKamal S Saini
Otto Metzger-Filho
Rodrigo Dienstmann
P2860cites workAntiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasisQ24608039
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Anti-vascular endothelial growth factor therapy for breast cancer: can we pick the winners?Q84069421
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Paclitaxel-carboplatin alone or with bevacizumab for non-small-cell lung cancerQ28278736
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancerQ29614302
Accelerated metastasis after short-term treatment with a potent inhibitor of tumor angiogenesisQ29614537
Integrating bevacizumab, everolimus, and lapatinib into current neoadjuvant chemotherapy regimen for primary breast cancer. Safety results of the GeparQuinto trialQ33390705
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Independent review of E2100: a phase III trial of bevacizumab plus paclitaxel versus paclitaxel in women with metastatic breast cancerQ33561160
Phase III study of bevacizumab plus docetaxel compared with placebo plus docetaxel for the first-line treatment of human epidermal growth factor receptor 2-negative metastatic breast cancerQ34022546
Disease course patterns after discontinuation of bevacizumab: pooled analysis of randomized phase III trialsQ34625332
Treatment-related mortality with bevacizumab in cancer patients: a meta-analysisQ34626720
Rapid vascular regrowth in tumors after reversal of VEGF inhibitionQ35052385
A phase II pilot trial incorporating bevacizumab into dose-dense doxorubicin and cyclophosphamide followed by paclitaxel in patients with lymph node positive breast cancer: a trial coordinated by the Eastern Cooperative Oncology GroupQ35693076
Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancerQ36024588
Association of vascular endothelial growth factor and vascular endothelial growth factor receptor-2 genetic polymorphisms with outcome in a trial of paclitaxel compared with paclitaxel plus bevacizumab in advanced breast cancer: ECOG 2100.Q37121685
A feasibility study of bevacizumab plus dose-dense doxorubicin-cyclophosphamide (AC) followed by nanoparticle albumin-bound paclitaxel in early-stage breast cancerQ37197579
Risk of venous thromboembolism with the angiogenesis inhibitor bevacizumab in cancer patients: a meta-analysisQ37328873
Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: a meta-analysisQ37501707
Bevacizumab for salvage treatment of metastatic breast cancer: a systemic review and meta-analysis of randomized controlled trialsQ37597935
Progression-free survival: gaining on overall survival as a gold standard and accelerating drug developmentQ37614173
Overall survival: a gold standard in search of a surrogate: the value of progression-free survival and time to progression as end points of drug efficacyQ37614176
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Bevacizumab in combination with taxanes for the first-line treatment of metastatic breast cancer.Q37718401
Increased Risk of Serious Hemorrhage with Bevacizumab in Cancer Patients: A Meta-AnalysisQ37807240
Bevacizumab/docetaxel association is more efficient than docetaxel alone in reducing breast and prostate cancer cell growth: a new paradigm for understanding the therapeutic effect of combined treatmentQ42930179
Bevacizumab and osteonecrosis of the jaw: incidence and association with bisphosphonate therapy in three large prospective trials in advanced breast cancerQ43111250
The antiangiogenic property of docetaxel is synergistic with a recombinant humanized monoclonal antibody against vascular endothelial growth factor or 2-methoxyestradiol but antagonized by endothelial growth factorsQ43579728
Congestive heart failure risk in patients with breast cancer treated with bevacizumab.Q44082273
RIBBON-1: randomized, double-blind, placebo-controlled, phase III trial of chemotherapy with or without bevacizumab for first-line treatment of human epidermal growth factor receptor 2-negative, locally recurrent or metastatic breast cancerQ44963911
First-line bevacizumab plus taxane-based chemotherapy for locally recurrent or metastatic breast cancer: safety and efficacy in an open-label study in 2,251 patients.Q53073357
Avastin's commercial march suffers setbackQ54650821
Intracranial hemorrhage in patients with cancer treated with bevacizumab: the Memorial Sloan-Kettering experienceQ60492076
Bevacizumab increases the risk of arterial ischemia: a large study in cancer patients with a focus on different subgroup outcomesQ82656539
Bevacizumab and breast cancer: the E2100 outlierQ82711662
Addition of bevacizumab to chemotherapy for treatment of solid tumors: similar results but different conclusionsQ82845146
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectbevacizumabQ413299
P304page(s)15-25
P577publication date2012-01-01
P1433published inDrug SafetyQ15724462
P1476titleBenefit-risk assessment of bevacizumab in the treatment of breast cancer
P478volume35

Reverse relations

cites work (P2860)
Q36248498Bevacizumab and Breast Cancer: A Meta-Analysis of First-Line Phase III Studies and a Critical Reappraisal of Available Evidence
Q37011741Breast cancer as a systemic disease: a view of metastasis
Q36751861Cardiovascular complications associated with novel angiogenesis inhibitors: emerging evidence and evolving perspectives
Q37417880Evaluation of a novel macromolecular cascade-polymer contrast medium for dynamic contrast-enhanced MRI monitoring of antiangiogenic bevacizumab therapy in a human melanoma model
Q51619428Systematic prioritization of cancer combination therapies: are we really on target?
Q37274132Targeting the tumor microenvironment: from understanding pathways to effective clinical trials

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