| scholarly article | Q13442814 |
| review article | Q7318358 |
| P356 | DOI | 10.1089/ARS.2009.2585 |
| P8608 | Fatcat ID | release_kahm6rm6oncefbibjgpyrycqvu |
| P698 | PubMed publication ID | 19309261 |
| P50 | author | Leonardo Scapozza | Q58448519 |
| P2093 | author name string | J David Lambeth | |
| Robert A Clark | |||
| Karl-Heinz Krause | |||
| Vincent Jaquet | |||
| P2860 | cites work | Approaches to Measure Chemical Similarity– a Review | Q28531485 |
| The effect of the inhibitor diphenylene iodonium on the superoxide-generating system of neutrophils. Specific labelling of a component polypeptide of the oxidase | Q42854050 | ||
| P433 | issue | 10 | |
| P921 | main subject | nitrogen oxide | Q424418 |
| P1104 | number of pages | 18 | |
| P304 | page(s) | 2535-2552 | |
| P577 | publication date | 2009-10-01 | |
| P1433 | published in | Antioxidants & Redox Signaling | Q4775078 |
| P1476 | title | Small-molecule NOX inhibitors: ROS-generating NADPH oxidases as therapeutic targets | |
| P478 | volume | 11 |
| Q33660799 | A novel and specific NADPH oxidase-1 (Nox1) small-molecule inhibitor blocks the formation of functional invadopodia in human colon cancer cells |
| Q36776546 | A novel nontoxic inhibitor of the activation of NADPH oxidase reduces reactive oxygen species production in mouse lung |
| Q36115323 | Adiponectin abates diabetes-induced endothelial dysfunction by suppressing oxidative stress, adhesion molecules, and inflammation in type 2 diabetic mice |
| Q39592033 | Amyloid-β-induced reactive oxygen species production and priming are differentially regulated by ion channels in microglia. |
| Q37576892 | Antioxidant therapeutics: Pandora's box. |
| Q42346973 | Antioxidants in the intensive care unit |
| Q42261961 | Apocynin regulates cytokine production of CD8(+) T cells |
| Q40810267 | Aquaporin-3-mediated hydrogen peroxide transport is required for NF-κB signalling in keratinocytes and development of psoriasis |
| Q53564509 | Association of NADPH oxidase polymorphisms with anthracycline-induced cardiotoxicity in the RICOVER-60 trial of patients with aggressive CD20(+) B-cell lymphoma. |
| Q41904227 | Bidirectional interactions between NOX2-type NADPH oxidase and the F-actin cytoskeleton in neuronal growth cones |
| Q28394560 | Bridged tetrahydroisoquinolines as selective NADPH oxidase 2 (Nox2) inhibitors |
| Q37426292 | Cellular and temporal expression of NADPH oxidase (NOX) isotypes after brain injury |
| Q49679592 | Cellular death, reactive oxygen species (ROS) and diabetic complications. |
| Q91994964 | Cellular redox state as a critical factor in initiating early embryonic-like program in embryonic stem cells |
| Q26751153 | Cerebral Small Vessel Disease: Targeting Oxidative Stress as a Novel Therapeutic Strategy? |
| Q38697307 | Characterization of potent and selective iodonium-class inhibitors of NADPH oxidases |
| Q35992729 | Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets |
| Q33885504 | Crossroads between peripheral atherosclerosis, western-type diet and skeletal muscle pathophysiology: emphasis on apolipoprotein E deficiency and peripheral arterial disease |
| Q38132120 | Current status of NADPH oxidase research in cardiovascular pharmacology |
| Q26849214 | Current strategies to minimize hepatic ischemia-reperfusion injury by targeting reactive oxygen species |
| Q35001796 | Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery |
| Q50092600 | Design, synthesis, and biological evaluation of inhibitors of the NADPH oxidase, Nox4. |
| Q48619319 | Different mechanisms of hydroxyl radical production susceptible to purine P2 receptor antagonists between carbon monoxide poisoning and exogenous ATP in rat striatum. |
| Q35984159 | Discovery of GSK2795039, a Novel Small Molecule NADPH Oxidase 2 Inhibitor |
| Q38998745 | Early NADPH oxidase-2 activation is crucial in phenylephrine-induced hypertrophy of H9c2 cells |
| Q36059818 | Ebselen and congeners inhibit NADPH oxidase 2-dependent superoxide generation by interrupting the binding of regulatory subunits |
| Q36674761 | Effects of iodonium-class flavin dehydrogenase inhibitors on growth, reactive oxygen production, cell cycle progression, NADPH oxidase 1 levels, and gene expression in human colon cancer cells and xenografts |
| Q37945969 | Emerging role of innate immunity in organ transplantation part III: the quest for transplant tolerance via prevention of oxidative allograft injury and its consequences |
| Q26861119 | Evolution of NADPH Oxidase Inhibitors: Selectivity and Mechanisms for Target Engagement |
| Q35532344 | Extending in silico mechanism-of-action analysis by annotating targets with pathways: application to cellular cytotoxicity readouts |
| Q37997802 | Free radical biology of the cardiovascular system |
| Q39124485 | Fulvene-5 inhibition of Nadph oxidases attenuates activation of epithelial sodium channels in A6 distal nephron cells |
| Q50054391 | Gastrodin Suppresses Pentylenetetrazole-Induced Seizures Progression by Modulating Oxidative Stress in Zebrafish. |
| Q38786128 | Graviola inhibits hypoxia-induced NADPH oxidase activity in prostate cancer cells reducing their proliferation and clonogenicity |
| Q28538546 | Haploinsufficiency of Def activates p53-dependent TGFβ signalling and causes scar formation after partial hepatectomy |
| Q33718483 | High-throughput assays for superoxide and hydrogen peroxide: design of a screening workflow to identify inhibitors of NADPH oxidases. |
| Q34124378 | Hydrogen peroxide primes heart regeneration with a derepression mechanism |
| Q51763200 | Identification of the NADPH Oxidase 4 Inhibiting Principle of Lycopus europaeus. |
| Q36717780 | Inhibition of the phospholipase A2 activity of peroxiredoxin 6 prevents lung damage with exposure to hyperoxia |
| Q36188186 | Integrating cytosolic phospholipase A₂ with oxidative/nitrosative signaling pathways in neurons: a novel therapeutic strategy for AD. |
| Q41015700 | Intermittent Hypoxia-Induced Parvalbumin-Immunoreactive Interneurons Loss and Neurobehavioral Impairment is Mediated by NADPH-Oxidase-2. |
| Q45728429 | Isoliquiritigenin-induced effects on Nrf2 mediated antioxidant defence in the HL-60 cell monocytic differentiation |
| Q35912784 | Mitigation of NADPH Oxidase 2 Activity as a Strategy to Inhibit Peroxynitrite Formation. |
| Q64948347 | NADPH Oxidase Hyperactivity Contributes to Cardiac Dysfunction and Apoptosis in Rats with Severe Experimental Pancreatitis through ROS-Mediated MAPK Signaling Pathway. |
| Q38038888 | NADPH Oxidases NOXs and DUOXs as putative targets for cancer therapy. |
| Q30155581 | NADPH oxidase (NOX) isoforms are inhibited by celastrol with a dual mode of action |
| Q39696544 | NADPH oxidase NOX1 controls autocrine growth of liver tumor cells through up-regulation of the epidermal growth factor receptor pathway |
| Q36339543 | NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion. |
| Q37766127 | NADPH oxidase and cardiac failure. |
| Q26859140 | NADPH oxidase in stroke and cerebrovascular disease |
| Q26821775 | NADPH oxidase inhibitors: a decade of discovery from Nox2ds to HTS |
| Q37873495 | NADPH oxidase inhibitors: a patent review |
| Q39680128 | NADPH oxidase-dependent and -independent mechanisms of reported inhibitors of reactive oxygen generation |
| Q39132107 | NADPH oxidase: its potential role in promotion of pulmonary arterial hypertension |
| Q42622634 | NADPH oxidases and atherosclerosis: unraveling the details. |
| Q38012354 | NADPH oxidases as therapeutic targets in ischemic stroke. |
| Q27001094 | NADPH oxidases in heart failure: poachers or gamekeepers? |
| Q38691764 | NADPH oxidases in oxidant production by microglia: activating receptors, pharmacology and association with disease |
| Q36302873 | NADPH oxidases: an overview from structure to innate immunity-associated pathologies |
| Q39988593 | NADPH oxidases: molecular understanding finally reaching the clinical level? |
| Q36336772 | NADPH oxidases: novel therapeutic targets for neurodegenerative diseases |
| Q41128491 | NOX Inhibitors - A Promising Avenue for Ischemic Stroke. |
| Q28266600 | NOX enzymes as drug targets |
| Q39546057 | NOX, NOX Who is There? The Contribution of NADPH Oxidase One to Beta Cell Dysfunction |
| Q35375986 | NOX1, 2, 4, 5: counting out oxidative stress |
| Q35985407 | NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress |
| Q28296660 | NOX2 interacts with podocyte TRPC6 channels and contributes to their activation by diacylglycerol: essential role of podocin in formation of this complex |
| Q42229194 | Nanosecond-Pulsed DBD Plasma-Generated Reactive Oxygen Species Trigger Immunogenic Cell Death in A549 Lung Carcinoma Cells through Intracellular Oxidative Stress |
| Q34757939 | Neuroprotective strategies involving ROS in Alzheimer disease |
| Q33632673 | New insights on NOX enzymes in the central nervous system |
| Q35006471 | Novel neuroinflammatory targets in the chronically injured spinal cord |
| Q35824748 | Nox Inhibitors & Therapies: Rational Design of Peptidic and Small Molecule Inhibitors |
| Q34308969 | Nox enzymes from fungus to fly to fish and what they tell us about Nox function in mammals |
| Q37852399 | Nox enzymes in allergic airway inflammation |
| Q35486123 | Nox2 B-loop peptide, Nox2ds, specifically inhibits the NADPH oxidase Nox2 |
| Q46506638 | Nox2-Mediated PI3K and Cofilin Activation Confers Alternate Redox Control of Macrophage Pinocytosis |
| Q38092960 | Nox4 and diabetic nephropathy: with a friend like this, who needs enemies? |
| Q35038777 | Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo. |
| Q41678966 | Perspectives of the Nrf-2 signaling pathway in cancer progression and therapy |
| Q92079223 | Pharmacological characterization of the seven human NOX isoforms and their inhibitors |
| Q26785525 | Pharmacology and Clinical Drug Candidates in Redox Medicine |
| Q36497800 | Pivotal role of reactive oxygen species in differential regulation of lipopolysaccharide-induced prostaglandins production in macrophages |
| Q37656051 | Protection against LPS-induced acute lung injury by a mechanism-based inhibitor of NADPH oxidase (type 2). |
| Q36482825 | ROS produced by NOX2 control in vitro development of cerebellar granule neurons development |
| Q42609911 | Rational design of small molecule inhibitors targeting the Rac GTPase-p67(phox) signaling axis in inflammation. |
| Q46513196 | Reactive Oxygen Species-mediated Loss of Phenotype of Parvalbumin Interneurons Contributes to Long-term Cognitive Impairments After Repeated Neonatal Ketamine Exposures |
| Q53263574 | Reactive oxygen species are related to ionic fluxes and volume decrease in apoptotic cerebellar granule neurons: role of NOX enzymes. |
| Q34241660 | Reactive oxygen species regulate the levels of dual oxidase (Duox1-2) in human neuroblastoma cells |
| Q37433974 | Reactive oxygen species, vascular Noxs, and hypertension: focus on translational and clinical research |
| Q46343029 | Recent Developments in the Probes and Assays for Measurement of the Activity of NADPH Oxidases. |
| Q38053776 | Recent development in the effects of statins on cardiovascular disease through Rac1 and NADPH oxidase |
| Q28391369 | Redox regulation of store-operated Ca2+ entry |
| Q35738096 | Redox signaling at invasive microdomains in cancer cells. |
| Q37446110 | Redox signaling in cardiovascular health and disease. |
| Q38835704 | Regulation of NADPH oxidases in skeletal muscle. |
| Q45066738 | Role of NADPH oxidase in radiation-induced pro-oxidative and pro-inflammatory pathways in mouse brain. |
| Q33632736 | Role of NADPH oxidases in liver fibrosis |
| Q35955745 | Role of apoptosis-inducing factor, proline dehydrogenase, and NADPH oxidase in apoptosis and oxidative stress |
| Q35150185 | Role of putative second transmembrane region of Nox2 protein in the structural stability and electron transfer of the phagocytic NADPH oxidase |
| Q33669214 | Small-Molecule Inhibitors of NADPH Oxidase 4 |
| Q36766182 | Strategies Aimed at Nox4 Oxidase Inhibition Employing Peptides from Nox4 B-Loop and C-Terminus and p22 (phox) N-Terminus: An Elusive Target |
| Q38007895 | Strategies for identifying synthetic peptides to act as inhibitors of NADPH oxidases, or "all that you did and did not want to know about Nox inhibitory peptides". |
| Q46508181 | Studying neuroprotective effect of Atorvastatin as a small molecule drug on high glucose-induced neurotoxicity in undifferentiated PC12 cells: role of NADPH oxidase. |
| Q89487254 | Targeting Evolutionary Conserved Oxidative Stress and Immunometabolic Pathways for the Treatment of Respiratory Infectious Diseases |
| Q37701322 | Targeting NADPH oxidase and phospholipases A2 in Alzheimer's disease |
| Q34285497 | Targeting NOX enzymes in the central nervous system: therapeutic opportunities. |
| Q38009736 | Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors |
| Q27023252 | Targeting the redox balance in inflammatory skin conditions |
| Q28743072 | Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism |
| Q36112519 | The 1027th target candidate in stroke: Will NADPH oxidase hold up? |
| Q37951441 | The DOCA-Salt Hypertensive Rat as a Model of Cardiovascular Oxidative and Inflammatory Stress |
| Q41660449 | The Future Challenge of Reactive Oxygen Species (ROS) in Hypertension: From Bench to Bed Side |
| Q42925757 | The NADPH oxidase NOX2 controls glutamate release: a novel mechanism involved in psychosis-like ketamine responses |
| Q34294854 | The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation |
| Q35122712 | The anti-oxidative role of micro-vesicles derived from human Wharton-Jelly mesenchymal stromal cells through NOX2/gp91(phox) suppression in alleviating renal ischemia-reperfusion injury in rats |
| Q38775962 | The potential for nanotechnology to improve delivery of therapy to the acute ischemic heart |
| Q33632757 | The quest for selective nox inhibitors and therapeutics: challenges, triumphs and pitfalls |
| Q38007896 | Towards specific NADPH oxidase inhibition by small synthetic peptides |
| Q83765725 | Tyrphostin AG490 reduces NAPDH oxidase activity and expression in the aorta of hypercholesterolemic apolipoprotein E-deficient mice |
| Q35450699 | Upstream regulators and downstream effectors of NADPH oxidases as novel therapeutic targets for diabetic kidney disease |
| Q36702523 | Which NADPH oxidase isoform is relevant for ischemic stroke? The case for nox 2. |
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