Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans

scientific article published on 09 July 2009

Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/JAPPLPHYSIOL.91234.2008
P932PMC publication ID2777794
P698PubMed publication ID19589955
P5875ResearchGate publication ID26659051

P2093author name stringArny A Ferrando
Marcas M Bamman
Jeong-Su Kim
David L Mayhew
James M Cross
P2860cites workAkt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivoQ28206290
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expressionQ28565720
Selective activation of AMPK-PGC-1alpha or PKB-TSC2-mTOR signaling can explain specific adaptive responses to endurance or resistance training-like electrical muscle stimulationQ28582298
c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells.Q31047994
Insulin resistance of muscle protein metabolism in agingQ33584429
Resistance exercise acutely increases MHC and mixed muscle protein synthesis rates in 78-84 and 23-32 yr oldsQ33897075
Resistance exercise maintains skeletal muscle protein synthesis during bed restQ34419921
The modular phosphorylation and activation of p70s6k.Q34434557
Efficacy of 3 days/wk resistance training on myofiber hypertrophy and myogenic mechanisms in young vs. older adultsQ34513823
Control of the size of the human muscle massQ35672556
mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k)Q36156171
Molecular determinants of skeletal muscle mass: getting the "AKT" togetherQ36241873
Multiple independent inputs are required for activation of the p70 S6 kinaseQ38295925
Decrease in Akt/PKB signalling in human skeletal muscle by resistance exerciseQ39974546
p38 MAP kinase regulates BMP-4-stimulated VEGF synthesis via p70 S6 kinase in osteoblastsQ40664065
Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways.Q40767544
Phosphorylation Sites in the Autoinhibitory Domain Participate in p70s6k Activation Loop PhosphorylationQ41034632
Potent myofiber hypertrophy during resistance training in humans is associated with satellite cell-mediated myonuclear addition: a cluster analysisQ42435285
Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men.Q42444632
Disassociation between the effects of amino acids and insulin on signaling, ubiquitin ligases, and protein turnover in human muscleQ42532366
Acute response of net muscle protein balance reflects 24-h balance after exercise and amino acid ingestionQ44185385
Resistance-training-induced adaptations in skeletal muscle protein turnover in the fed state.Q44254461
Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscleQ44560775
Aging does not alter the mechanosensitivity of the p38, p70S6k, and JNK2 signaling pathways in skeletal muscleQ45054272
Fasted-state skeletal muscle protein synthesis after resistance exercise is altered with trainingQ46624482
Suction applied to a muscle biopsy maximizes sample size.Q47273109
Myogenic protein expression before and after resistance loading in 26- and 64-yr-old men and women.Q47448460
Mechanical ventilation-induced diaphragmatic atrophy is associated with oxidative injury and increased proteolytic activityQ51698128
Resistance exercise-induced increase in muscle mass correlates with p70S6 kinase phosphorylation in human subjects.Q51905788
Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscleQ53608576
Resting and load-induced levels of myogenic gene transcripts differ between older adults with demonstrable sarcopenia and young men and womenQ53849584
Resistance training reduces the acute exercise-induced increase in muscle protein turnoverQ54108942
Changes in human muscle protein synthesis after resistance exerciseQ54261834
Mixed muscle protein synthesis and breakdown after resistance exercise in humansQ55067147
Early signaling responses to divergent exercise stimuli in skeletal muscle from well-trained humansQ58449853
Akt signalling through GSK-3beta, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophyQ60714063
Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humansQ72655300
Acute effects of resistance exercise on muscle protein synthesis rate in young and elderly men and womenQ72917392
Phosphorylation of p70(S6k) correlates with increased skeletal muscle mass following resistance exerciseQ77788757
Muscle protein breakdown and the critical role of the ubiquitin-proteasome pathway in normal and disease statesQ77897177
Cluster analysis tests the importance of myogenic gene expression during myofiber hypertrophy in humansQ80065290
Impaired anabolic response of muscle protein synthesis is associated with S6K1 dysregulation in elderly humansQ80471118
Age differences in knee extension power, contractile velocity, and fatigabilityQ80526520
Load-mediated downregulation of myostatin mRNA is not sufficient to promote myofiber hypertrophy in humans: a cluster analysisQ80731100
Modulation of the dystrophin-associated protein complex in response to resistance training in young and older menQ80925263
Mixed muscle and hepatic derived plasma protein metabolism is differentially regulated in older and younger men following resistance exerciseQ81256235
Efficacy of myonuclear addition may explain differential myofiber growth among resistance-trained young and older men and womenQ83986218
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)1655-1662
P577publication date2009-07-09
P1433published inJournal of Applied PhysiologyQ1091719
P1476titleTranslational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans
P478volume107

Reverse relations

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