Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle

scientific article

Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1113/JPHYSIOL.2006.113175
P932PMC publication ID1890364
P698PubMed publication ID16873412
P5875ResearchGate publication ID6913855

P50authorBlake B. RasmussenQ42425454
Elena VolpiQ53537198
Hans C DreyerQ92171772
P2093author name stringSatoshi Fujita
David L Chinkes
Jerson G Cadenas
P2860cites workmTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machineryQ24302549
The AMP-activated protein kinase--fuel gauge of the mammalian cell?Q24315074
Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteinsQ24519078
Regulation of elongation factor 2 kinase by p90(RSK1) and p70 S6 kinase.Q24535599
TSC2 mediates cellular energy response to control cell growth and survivalQ27860970
AMP-activated protein kinase suppresses protein synthesis in rat skeletal muscle through down-regulated mammalian target of rapamycin (mTOR) signalingQ28216932
Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesisQ28218978
Stimulation of the AMP-activated protein kinase leads to activation of eukaryotic elongation factor 2 kinase and to its phosphorylation at a novel site, serine 398Q28237559
The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stressesQ28240102
Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient statusQ28245724
Rheb binds and regulates the mTOR kinaseQ28247033
Redox regulation of the nutrient-sensitive raptor-mTOR pathway and complexQ28273915
AMP-activated protein kinase, a metabolic master switch: possible roles in type 2 diabetesQ28369312
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinaseQ28567006
Caspase cleavage of initiation factor 4E-binding protein 1 yields a dominant inhibitor of cap-dependent translation and reveals a novel regulatory motifQ28579562
Selective activation of AMPK-PGC-1alpha or PKB-TSC2-mTOR signaling can explain specific adaptive responses to endurance or resistance training-like electrical muscle stimulationQ28582298
Inactivation of acetyl-CoA carboxylase and activation of AMP-activated protein kinase in muscle during exerciseQ28610612
Growing roles for the mTOR pathwayQ29616212
Branched-chain amino acids increase p70S6k phosphorylation in human skeletal muscle after resistance exerciseQ33976354
Analysis of the role of the AMP-activated protein kinase in the response to cellular stress.Q33979128
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells.Q34438345
Regulation of peptide-chain elongation in mammalian cellsQ34992462
Contractile and nutritional regulation of human muscle growthQ35185647
Control of muscle protein kinetics by acid-base balanceQ35977143
New roles for the LKB1-->AMPK pathway.Q36076064
Effect of exercise on synthesis and degradation of muscle proteinQ41810633
Exercise induces isoform-specific increase in 5'AMP-activated protein kinase activity in human skeletal muscle.Q42490447
Response of muscle protein turnover to insulin after acute exercise and trainingQ42855078
Acute metabolic acidosis decreases muscle protein synthesis but not albumin synthesis in humansQ43812623
Progressive increase in human skeletal muscle AMPKalpha2 activity and ACC phosphorylation during exerciseQ43879217
Contribution of insulin to the translational control of protein synthesis in skeletal muscle by leucineQ43948696
Regulation of 5'AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscleQ44253307
Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscleQ44560775
Effect of exercise intensity on skeletal muscle AMPK signaling in humansQ44564007
Leg glucose and protein metabolism during an acute bout of resistance exercise in humans.Q44934583
Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exerciseQ45071070
Akt activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activityQ46606786
Short-term exercise training in humans reduces AMPK signalling during prolonged exercise independent of muscle glycogenQ46624502
Anabolic signaling and protein synthesis in human skeletal muscle after dynamic shortening or lengthening exerciseQ46786550
Increase in S6K1 phosphorylation in human skeletal muscle following resistance exercise occurs mainly in type II muscle fibersQ46910048
Response of protein synthesis to hypercapnia in rats: independent effects of acidosis and hypothermiaQ47771834
Acute metabolic acidosis inhibits muscle protein synthesis in ratsQ51020759
Effect of exercise intensity on skeletal muscle malonyl-CoA and acetyl-CoA carboxylaseQ51535541
Effect of exercise and recovery on muscle protein synthesis in human subjectsQ52471662
An oral essential amino acid-carbohydrate supplement enhances muscle protein anabolism after resistance exerciseQ54063913
Leg Blood Flow during Exercise in ManQ54465143
The time course for elevated muscle protein synthesis following heavy resistance exercise.Q55066374
Mixed muscle protein synthesis and breakdown after resistance exercise in humansQ55067147
The determination of low d5-phenylalanine enrichment (0.002-0.09 atom percent excess), after conversion to phenylethylamine, in relation to protein turnover studies by gass chromatography/electron ionization mass spectrometryQ56227948
Exercise rapidly increases eukaryotic elongation factor 2 phosphorylation in skeletal muscle of menQ58172158
Early signaling responses to divergent exercise stimuli in skeletal muscle from well-trained humansQ58449853
Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exerciseQ58449877
Effect of Exercise on Protein Turnover in ManQ70939134
Protein synthesis versus energy state in contracting muscles of perfused rat hindlimbQ71345508
Increased rates of muscle protein turnover and amino acid transport after resistance exercise in humansQ72655300
Postexercise recovery of skeletal muscle malonyl-CoA, acetyl-CoA carboxylase, and AMP-activated protein kinaseQ77520236
Phosphorylation of p70(S6k) correlates with increased skeletal muscle mass following resistance exerciseQ77788757
P433issuePt 2
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
P304page(s)613-624
P577publication date2006-07-27
P1433published inJournal of PhysiologyQ7743612
P1476titleResistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle
P478volume576

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cites work (P2860)
Q57794858A Brief Review on Concurrent Training: From Laboratory to the Field
Q28580387A Ca(2+)-calmodulin-eEF2K-eEF2 signalling cascade, but not AMPK, contributes to the suppression of skeletal muscle protein synthesis during contractions
Q37251400A chronic increase in physical activity inhibits fed-state mTOR/S6K1 signaling and reduces IRS-1 serine phosphorylation in rat skeletal muscle.
Q33705520A comparison of 2H2O and phenylalanine flooding dose to investigate muscle protein synthesis with acute exercise in rats
Q37541118A metabolic link to skeletal muscle wasting and regeneration
Q30514019A moderate acute increase in physical activity enhances nutritive flow and the muscle protein anabolic response to mixed nutrient intake in older adults.
Q36527961AMP kinase activation improves angiogenesis in pulmonary artery endothelial cells with in utero pulmonary hypertension
Q46813693AMPK activation attenuates S6K1, 4E-BP1, and eEF2 signaling responses to high-frequency electrically stimulated skeletal muscle contractions
Q37834161AMPK activation, a preventive therapeutic target in the transition from cardiac injury to heart failure
Q37386321AMPK and the biochemistry of exercise: implications for human health and disease
Q47781006AMPK in skeletal muscle function and metabolism.
Q33976384Activation of mTORC1 signaling and protein synthesis in human muscle following blood flow restriction exercise is inhibited by rapamycin.
Q42608770Acute high-caffeine exposure increases autophagic flux and reduces protein synthesis in C2C12 skeletal myotubes
Q35588649Acute molecular responses to concurrent resistance and high-intensity interval exercise in untrained skeletal muscle
Q47134495Acute resistance exercise induces Sestrin2 phosphorylation and p62 dephosphorylation in human skeletal muscle.
Q51740157Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics
Q37017913Addition of carbohydrate or alanine to an essential amino acid mixture does not enhance human skeletal muscle protein anabolism
Q37339750Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling
Q27024546Age effect on myocellular remodeling: response to exercise and nutrition in humans
Q55053241Age-related differences in lean mass, protein synthesis and skeletal muscle markers of proteolysis after bed rest and exercise rehabilitation.
Q42444632Age-related differences in the dose-response relationship of muscle protein synthesis to resistance exercise in young and old men.
Q36507525Aging Reduces the Activation of the mTORC1 Pathway after Resistance Exercise and Protein Intake in Human Skeletal Muscle: Potential Role of REDD1 and Impaired Anabolic Sensitivity
Q35033673Aging and microRNA expression in human skeletal muscle: a microarray and bioinformatics analysis
Q36454435Aging differentially affects human skeletal muscle amino acid transporter expression when essential amino acids are ingested after exercise
Q37016672Aging differentially affects human skeletal muscle microRNA expression at rest and after an anabolic stimulus of resistance exercise and essential amino acids
Q35166239Aging impairs contraction-induced human skeletal muscle mTORC1 signaling and protein synthesis.
Q85030250Ambulating With Pulmonary Artery or Femoral Catheters in Place
Q33840291An increase in essential amino acid availability upregulates amino acid transporter expression in human skeletal muscle
Q55107416Anabolic Heterogeneity Following Resistance Training: A Role for Circadian Rhythm?
Q38693701Andrographolide Suppresses MV4-11 Cell Proliferation through the Inhibition of FLT3 Signaling, Fatty Acid Synthesis and Cellular Iron Uptake
Q33976336Application of the [γ-32P] ATP kinase assay to study anabolic signaling in human skeletal muscle
Q35294194Association between myosin heavy chain protein isoforms and intramuscular anabolic signaling following resistance exercise in trained men.
Q38189267Autophagic cellular responses to physical exercise in skeletal muscle.
Q27000625Autophagy is essential to support skeletal muscle plasticity in response to endurance exercise
Q35993635Bed rest impairs skeletal muscle amino acid transporter expression, mTORC1 signaling, and protein synthesis in response to essential amino acids in older adults.
Q45078495Betaine supplementation enhances anabolic endocrine and Akt signaling in response to acute bouts of exercise
Q33841125Blood flow restriction exercise stimulates mTORC1 signaling and muscle protein synthesis in older men
Q35902939Both resistance- and endurance-type exercise reduce the prevalence of hyperglycaemia in individuals with impaired glucose tolerance and in insulin-treated and non-insulin-treated type 2 diabetic patients
Q36934986Cancer cachexia prevention via physical exercise: molecular mechanisms
Q39043465Carbohydrate intake and resistance-based exercise: are current recommendations reflective of actual need?
Q38110504Characterization and Regulation of Mechanical Loading‐Induced Compensatory Muscle Hypertrophy
Q28565436Chronic paraplegia-induced muscle atrophy downregulates the mTOR/S6K1 signaling pathway
Q36309131Co-ingestion of carbohydrate and whey protein increases fasted rates of muscle protein synthesis immediately after resistance exercise in rats
Q47388796Combined effects of low-intensity blood flow restriction training and high-intensity resistance training on muscle strength and size
Q38421077Comparative effects of whey protein versus L-leucine on skeletal muscle protein synthesis and markers of ribosome biogenesis following resistance exercise
Q28267408Comparison of availability and plasma clearance rates of β-hydroxy-β-methylbutyrate delivery in the free acid and calcium salt forms
Q34616237Comparison of bolus injection and constant infusion methods for measuring muscle protein fractional synthesis rate in humans
Q53130147Concurrent exercise incorporating high-intensity interval or continuous training modulates mTORC1 signaling and microRNA expression in human skeletal muscle
Q38923257Concurrent exercise training: do opposites distract?
Q51412357Contraction intensity and feeding affect collagen and myofibrillar protein synthesis rates differently in human skeletal muscle
Q83189082Contraction-induced changes in TNFalpha and Akt-mediated signalling are associated with increased myofibrillar protein in rat skeletal muscle
Q39974546Decrease in Akt/PKB signalling in human skeletal muscle by resistance exercise
Q52605239Dietary protein and exercise training in ageing
Q61788535Differential effects of resistance and endurance exercise in the fed state on signalling molecule phosphorylation and protein synthesis in human muscle
Q46246829Differential stimulation of myofibrillar and sarcoplasmic protein synthesis with protein ingestion at rest and after resistance exercise
Q37137271Does AMP-activated protein kinase negatively mediate aged fast-twitch skeletal muscle mass?
Q37985564Does Exercise-Induced Muscle Damage Play a Role in Skeletal Muscle Hypertrophy?
Q55431394Effect of 8-week leucine supplementation and resistance exercise training on muscle hypertrophy and satellite cell activation in rats.
Q48005675Effect of acute treadmill exercise on cisplatin-induced muscle atrophy in the mouse
Q93224066Effect of eccentric action velocity on expression of genes related to myostatin signaling pathway in human skeletal muscle
Q58556360Effect of exercise modality on markers of insulin sensitivity and blood glucose control in pregnancies complicated with gestational diabetes mellitus: a systematic review
Q30383045Effects of Arachidonic Acid Supplementation on Acute Anabolic Signaling and Chronic Functional Performance and Body Composition Adaptations.
Q58750306Effects of Protein Supplementation on Performance and Recovery in Resistance and Endurance Training
Q33638591Effects of alfa-hydroxy-isocaproic acid on body composition, DOMS and performance in athletes.
Q28109460Effects of contraction and insulin on protein synthesis, AMP-activated protein kinase and phosphorylation state of translation factors in rat skeletal muscle
Q41999349Effects of leucine supplementation and resistance training on myopathy of diabetic rats
Q42173246Effects of treadmill exercise on skeletal muscle mTOR signaling pathway in high-fat diet-induced obese mice
Q47969599Electrical pulse stimulation: an in vitro exercise model for the induction of human skeletal muscle cell hypertrophy. A proof-of-concept study
Q35094227Endurance exercise induces REDD1 expression and transiently decreases mTORC1 signaling in rat skeletal muscle
Q95660532Enhanced skeletal muscle insulin sensitivity after acute resistance-type exercise is upregulated by rapamycin-sensitive mTOR complex 1 inhibition
Q37190170Essential amino acid and carbohydrate ingestion before resistance exercise does not enhance postexercise muscle protein synthesis
Q33660488Essential amino acid ingestion alters expression of genes associated with amino acid sensing, transport, and mTORC1 regulation in human skeletal muscle.
Q43419044Eukaryotic initiation factor 2B epsilon induces cap-dependent translation and skeletal muscle hypertrophy
Q34204391Excess leucine intake enhances muscle anabolic signaling but not net protein anabolism in young men and women
Q55030690Exercise and Nutrition Strategies to Counteract Sarcopenic Obesity.
Q92518945Exercise and Sirtuins: A Way to Mitochondrial Health in Skeletal Muscle
Q38017323Exercise intensity and muscle hypertrophy in blood flow–restricted limbs and non‐restricted muscles: a brief review
Q35787793Exercise, amino acids, and aging in the control of human muscle protein synthesis.
Q54385382Exercise-induced AMPK activation does not interfere with muscle hypertrophy in response to resistance training in men.
Q37233128Expression of growth-related genes in young and older human skeletal muscle following an acute stimulation of protein synthesis
Q34153509Free acid gel form of β-hydroxy-β-methylbutyrate (HMB) improves HMB clearance from plasma in human subjects compared with the calcium HMB salt.
Q54491763Genetic Strain-Dependent Protein Metabolism and Muscle Hypertrophy Under Chronic Isometric Training in Rat Gastrocnemius Muscle
Q34464470Heat shock response and autophagy--cooperation and control
Q54620933Heat stress enhances mTOR signaling after resistance exercise in human skeletal muscle
Q54334425High force development augments skeletal muscle signalling in resistance exercise modes equalized for time under tension.
Q30729568How to explain exercise-induced phenotype from molecular data: rethink and reconstruction based on AMPK and mTOR signaling
Q27693892Human muscle protein turnover—why is it so variable?
Q37710664Humanin skeletal muscle protein levels increase after resistance training in men with impaired glucose metabolism
Q46291569Immobilization induces anabolic resistance in human myofibrillar protein synthesis with low and high dose amino acid infusion
Q54608690Impact of protein coingestion on muscle protein synthesis during continuous endurance type exercise.
Q45013210Increased net muscle protein balance in response to simultaneous and separate ingestion of carbohydrate and essential amino acids following resistance exercise.
Q43148361Increased p70s6k phosphorylation during intake of a protein-carbohydrate drink following resistance exercise in the fasted state.
Q26748964Influence of Acute and Chronic Exercise on Glucose Uptake
Q27003307Influence of Amino Acids, Dietary Protein, and Physical Activity on Muscle Mass Development in Humans
Q47799259Influence of past injurious exercise on fiber type-specific acute anabolic response to resistance exercise in skeletal muscle.
Q54345624Influence of resistance exercise intensity and metabolic stress on anabolic signaling and expression of myogenic genes in skeletal muscle.
Q39634846Ingestion of 10 grams of whey protein prior to a single bout of resistance exercise does not augment Akt/mTOR pathway signaling compared to carbohydrate.
Q34032001Insulin stimulates human skeletal muscle protein synthesis via an indirect mechanism involving endothelial-dependent vasodilation and mammalian target of rapamycin complex 1 signaling
Q42251241Intake of a Ketone Ester Drink during Recovery from Exercise Promotes mTORC1 Signaling but Not Glycogen Resynthesis in Human Muscle
Q51728269Intake of branched-chain or essential amino acids attenuates the elevation in muscle levels of PGC-1α4 mRNA caused by resistance exercise.
Q34485229Intense resistance exercise induces early and transient increases in ryanodine receptor 1 phosphorylation in human skeletal muscle
Q36620195Interactions between exercise and nutrition to prevent muscle waste during ageing
Q38204299Interference between concurrent resistance and endurance exercise: molecular bases and the role of individual training variables
Q38669070Intramuscular Anabolic Signaling and Endocrine Response Following Resistance Exercise: Implications for Muscle Hypertrophy
Q90151151Ketogenic Diet and Skeletal Muscle Hypertrophy: A Frenemy Relationship?
Q37383513LKB1 and AMP-activated protein kinase control of mTOR signalling and growth
Q64083817Lactate production without hypoxia in skeletal muscle during electrical cycling: Crossover study of femoral venous-arterial differences in healthy volunteers
Q36521506Leucine partially protects muscle mass and function during bed rest in middle-aged adults
Q34330791Leucine-enriched amino acid ingestion after resistance exercise prolongs myofibrillar protein synthesis and amino acid transporter expression in older men.
Q37251386Leucine-enriched essential amino acid and carbohydrate ingestion following resistance exercise enhances mTOR signaling and protein synthesis in human muscle.
Q40593691Leucine-enriched essential amino acids attenuate muscle soreness and improve muscle protein synthesis after eccentric contractions in rats
Q37135107Leucine-enriched nutrients and the regulation of mammalian target of rapamycin signalling and human skeletal muscle protein synthesis
Q48155681Linking Cancer Cachexia-Induced Anabolic Resistance to Skeletal Muscle Oxidative Metabolism.
Q38614834Low Skeletal Muscle Mass is Associated with the Risk of Low Bone Mineral Density in Urban Dwelling Premenopausal Women.
Q33658994Low-load high volume resistance exercise stimulates muscle protein synthesis more than high-load low volume resistance exercise in young men.
Q36178553MAFbx, MuRF1, and the stress-activated protein kinases are upregulated in muscle cells during total knee arthroplasty
Q39262984MYC and AMPK-Save Energy or Die!
Q34802103Mammalian target of rapamycin complex 1 activation is required for the stimulation of human skeletal muscle protein synthesis by essential amino acids
Q53687296May the force be with you: why resistance training is essential for subjects with type 2 diabetes mellitus without complications
Q38383123Mechanical cues in orofacial tissue engineering and regenerative medicine.
Q92628963Mechanical loading stimulates hypertrophy in tissue-engineered skeletal muscle: Molecular and phenotypic responses
Q36973429Mechanical stimuli of skeletal muscle: implications on mTOR/p70s6k and protein synthesis.
Q28079049Mechanosensitive Molecular Networks Involved in Transducing Resistance Exercise-Signals into Muscle Protein Accretion
Q38922063Mixed lactate and caffeine compound increases satellite cell activity and anabolic signals for muscle hypertrophy.
Q64257830Moderate-intensity aerobic exercise improves skeletal muscle quality in older adults
Q37486043Molecular responses to high-intensity interval exercise
Q37485998Molecular responses to strength and endurance training: are they incompatible?
Q42365569Molecular, neuromuscular, and recovery responses to light versus heavy resistance exercise in young men.
Q54978305Muscle Protein Anabolic Resistance to Essential Amino Acids Does Not Occur in Healthy Older Adults Before or After Resistance Exercise Training.
Q34085586Muscle protein breakdown has a minor role in the protein anabolic response to essential amino acid and carbohydrate intake following resistance exercise.
Q43819395Muscle size and arterial stiffness after blood flow‐restricted low‐intensity resistance training in older adults
Q46703582Muscle time under tension during resistance exercise stimulates differential muscle protein sub-fractional synthetic responses in men.
Q34579211Nutrient signalling in the regulation of human muscle protein synthesis
Q28307009Nutritional and contractile regulation of human skeletal muscle protein synthesis and mTORC1 signaling
Q36948650Nutritional interventions to promote post-exercise muscle protein synthesis.
Q50421405Paralytic and non-paralytic muscle adaptations to exercise training vs. high protein diet in individuals with long-standing spinal cord injury
Q42425417Paraplegia increases skeletal muscle autophagy
Q84229953Phosphatidic acid: a novel mechanical mechanism for how resistance exercise activates mTORC1 signalling
Q37486029Physiologic and molecular bases of muscle hypertrophy and atrophy: impact of resistance exercise on human skeletal muscle (protein and exercise dose effects).
Q48141398Post-absorptive muscle protein turnover affects resistance training hypertrophy.
Q34485018Post-exercise cold water immersion attenuates acute anabolic signalling and long-term adaptations in muscle to strength training
Q38479055Post-exercise impact of ingested whey protein hydrolysate on gene expression profiles in rat skeletal muscle: activation of extracellular signal-regulated kinase 1/2 and hypoxia-inducible factor-1α.
Q33793228Post-exercise protein synthesis rates are only marginally higher in type I compared with type II muscle fibres following resistance-type exercise
Q79233726Predominant alpha2/beta2/gamma3 AMPK activation during exercise in human skeletal muscle
Q26749616Protein Considerations for Optimising Skeletal Muscle Mass in Healthy Young and Older Adults
Q37082292Protein blend ingestion following resistance exercise promotes human muscle protein synthesis
Q46631241Protein coingestion stimulates muscle protein synthesis during resistance-type exercise
Q37370849Protein turnover, amino acid requirements and recommendations for athletes and active populations
Q37175505Proteins regulating cap-dependent translation are downregulated during total knee arthroplasty
Q47753820Randomized, four-arm, dose-response clinical trial to optimize resistance exercise training for older adults with age-related muscle atrophy.
Q46135983Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis
Q36924317Rapamycin does not affect post-absorptive protein metabolism in human skeletal muscle
Q54617034Rapid induction of REDD1 expression by endurance exercise in rat skeletal muscle
Q35994715Reactive hyperemia is not responsible for stimulating muscle protein synthesis following blood flow restriction exercise
Q92723887Recent Data on Cellular Component Turnover: Focus on Adaptations to Physical Exercise
Q36781795Reduced AMPK-ACC and mTOR signaling in muscle from older men, and effect of resistance exercise.
Q35583549Regulation of survival gene hsp70
Q37346834Regulatory mechanisms of skeletal muscle protein turnover during exercise.
Q50879152Relationship between exercise volume and muscle protein synthesis in a rat model of resistance exercise
Q47129256Repeated bouts of resistance exercise with short recovery periods activates mTOR signaling, but not protein synthesis, in mouse skeletal muscle.
Q34707947Repeated resistance exercise training induces different changes in mRNA expression of MAFbx and MuRF-1 in human skeletal muscle.
Q35773058Resistance Exercise Training Alters Mitochondrial Function in Human Skeletal Muscle.
Q33732617Resistance Training for Glycemic Control, Muscular Strength, and Lean Body Mass in Old Type 2 Diabetic Patients: A Meta-Analysis
Q37638217Resistance exercise and nutrition to counteract muscle wasting
Q46537256Resistance exercise biology: manipulation of resistance exercise programme variables determines the responses of cellular and molecular signalling pathways
Q54568265Resistance exercise enhances the molecular signaling of mitochondrial biogenesis induced by endurance exercise in human skeletal muscle
Q37033519Resistance exercise increases human skeletal muscle AS160/TBC1D4 phosphorylation in association with enhanced leg glucose uptake during postexercise recovery.
Q33895553Resistance exercise increases leg muscle protein synthesis and mTOR signalling independent of sex
Q43788186Resistance exercise induced mTORC1 signaling is not impaired by subsequent endurance exercise in human skeletal muscle
Q38685326Resistance exercise initiates mechanistic target of rapamycin (mTOR) translocation and protein complex co-localisation in human skeletal muscle
Q51905788Resistance exercise-induced increase in muscle mass correlates with p70S6 kinase phosphorylation in human subjects.
Q41851925Resistance training for diabetes prevention and therapy: experimental findings and molecular mechanisms
Q36498001Role of Ingested Amino Acids and Protein in the Promotion of Resistance Exercise-Induced Muscle Protein Anabolism.
Q38128640Role of stearoyl-CoA desaturase-1 in skeletal muscle function and metabolism
Q46034890Rosiglitazone-induced heart remodelling is associated with enhanced turnover of myofibrillar protein and mTOR activation.
Q36952785Safety and Efficacy of Mobility Interventions in Patients with Femoral Catheters in the ICU: A Prospective Observational Study
Q36633369Sake Protein Supplementation Affects Exercise Performance and Biochemical Profiles in Power-Exercise-Trained Mice
Q36956001Sequential muscle biopsies during a 6-h tracer infusion do not affect human mixed muscle protein synthesis and muscle phenylalanine kinetics.
Q46066667Sirolimus and mTORC1: centre stage in the story of what makes muscles bigger?
Q50228186Skeletal Muscle Hypertrophy with Concurrent Exercise Training: Contrary Evidence for an Interference Effect
Q37395559Skeletal Muscle Protein Balance and Metabolism in the Elderly
Q34036589Skeletal muscle Ras-related GTP binding B mRNA and protein expression is increased after essential amino acid ingestion in healthy humans
Q35108785Skeletal muscle amino acid transporter expression is increased in young and older adults following resistance exercise.
Q36758018Skeletal muscle autophagy and protein breakdown following resistance exercise are similar in younger and older adults
Q43827533Skeletal muscle eEF2 and 4EBP1 phosphorylation during endurance exercise is dependent on intensity and muscle fiber type
Q47450273Skeletal muscle performance and ageing
Q37273785Skeletal muscle protein anabolic response to resistance exercise and essential amino acids is delayed with aging
Q35447810Skeletal muscle protein metabolism in the elderly: Interventions to counteract the 'anabolic resistance' of ageing
Q33816833Skeletal muscle signaling associated with impaired glucose tolerance in spinal cord-injured men and the effects of contractile activity
Q39231283Soy-Dairy Protein Blend or Whey Protein Isolate Ingestion Induces Similar Postexercise Muscle Mechanistic Target of Rapamycin Complex 1 Signaling and Protein Synthesis Responses in Older Men.
Q33708188Soy-dairy protein blend and whey protein ingestion after resistance exercise increases amino acid transport and transporter expression in human skeletal muscle.
Q37863056Stretching skeletal muscle in vitro: does it replicate in vivo physiology?
Q33745051Supraphysiological hyperinsulinaemia is necessary to stimulate skeletal muscle protein anabolism in older adults: evidence of a true age-related insulin resistance of muscle protein metabolism.
Q36246665Targeting anabolic impairment in response to resistance exercise in older adults with mobility impairments: potential mechanisms and rehabilitation approaches.
Q36119634The Differential Hormonal Milieu of Morning versus Evening May Have an Impact on Muscle Hypertrophic Potential
Q92087685The Psychiatric Risk Gene NT5C2 Regulates Adenosine Monophosphate-Activated Protein Kinase Signaling and Protein Translation in Human Neural Progenitor Cells
Q42838952The acute effects of strength, endurance and concurrent exercises on the Akt/mTOR/p70(S6K1) and AMPK signaling pathway responses in rat skeletal muscle
Q35759869The anabolic response to resistance exercise and a protein-rich meal is not diminished by age
Q42975275The degree of p70 S6k and S6 phosphorylation in human skeletal muscle in response to resistance exercise depends on the training volume
Q47250783The development of skeletal muscle hypertrophy through resistance training: the role of muscle damage and muscle protein synthesis.
Q38639794The effect of different acute muscle contraction regimens on the expression of muscle proteolytic signaling proteins and genes.
Q45938844The effect of electrical muscle stimulation on the prevention of disuse muscle atrophy in patients with consciousness disturbance in the intensive care unit
Q35913175The effect of exercise on expression of myokine and angiogenesis mRNA in skeletal muscle of high fat diet induced obese rat.
Q33844350The effects of age and muscle contraction on AMPK activity and heterotrimer composition
Q64114699The effects of resistance training on bone mineral density and bone quality in type 2 diabetic rats
Q38569753The metabolic and temporal basis of muscle hypertrophy in response to resistance exercise
Q36920587The molecular bases of training adaptation
Q51481701The muscle‐hypertrophic effect of clenbuterol is additive to the hypertrophic effect of myostatin suppression
Q52638050The putative leucine sensor Sestrin2 is hyperphosphorylated by acute resistance exercise but not protein ingestion in human skeletal muscle.
Q39501565The response of muscle protein synthesis following whole-body resistance exercise is greater following 40 g than 20 g of ingested whey protein
Q37160004The role of mTOR signalling in the regulation of skeletal muscle mass in a rodent model of resistance exercise.
Q38179978The role of mTORC1 in regulating protein synthesis and skeletal muscle mass in response to various mechanical stimuli.
Q34108429The role of milk- and soy-based protein in support of muscle protein synthesis and muscle protein accretion in young and elderly persons
Q45995855The role of phosphoinositide 3-kinase and phosphatidic acid in the regulation of mammalian target of rapamycin following eccentric contractions.
Q37043350The serine protease, dipeptidyl peptidase IV as a myokine: dietary protein and exercise mimetics as a stimulus for transcription and release
Q57577236Timing and distribution of protein ingestion during prolonged recovery from resistance exercise alters myofibrillar protein synthesis
Q51385155Training in the fasted state facilitates re-activation of eEF2 activity during recovery from endurance exercise.
Q37422140Translational signaling responses preceding resistance training-mediated myofiber hypertrophy in young and old humans
Q44820634Vitamin C administration attenuates overload‐induced skeletal muscle hypertrophy in rats
Q28384458Vitamin C and E supplementation alters protein signalling after a strength training session, but not muscle growth during 10 weeks of training
Q40377091Whey protein ingestion activates mTOR-dependent signalling after resistance exercise in young men: a double-blinded randomized controlled trial
Q87025443Whey protein intake after resistance exercise activates mTOR signaling in a dose-dependent manner in human skeletal muscle
Q90136344Whey protein sweetened with Stevia rebaudiana Bertoni (Bert.) increases mitochondrial biogenesis markers in the skeletal muscle of resistance-trained rats
Q37638216mTOR function in skeletal muscle: a focal point for overnutrition and exercise
Q38003176mTORC1 and the regulation of skeletal muscle anabolism and mass

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