review article | Q7318358 |
scholarly article | Q13442814 |
P50 | author | Neil B Ruderman | Q43064674 |
P2093 | author name string | Erik A Richter | |
P2860 | cites work | Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade | Q21245891 |
Metformin Increases AMP-Activated Protein Kinase Activity in Skeletal Muscle of Subjects With Type 2 Diabetes | Q22241283 | ||
Reduction in the Incidence of Type 2 Diabetes with Lifestyle Intervention or Metformin | Q22250892 | ||
Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia | Q24290495 | ||
Structural basis for AMP binding to mammalian AMP-activated protein kinase | Q24293456 | ||
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AMP kinase is required for mitochondrial biogenesis in skeletal muscle in response to chronic energy deprivation | Q24541475 | ||
The AMP-activated protein kinase alpha2 catalytic subunit controls whole-body insulin sensitivity | Q24554361 | ||
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Skeletal muscle-selective knockout of LKB1 increases insulin sensitivity, improves glucose homeostasis, and decreases TRB3 | Q24672153 | ||
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Resveratrol improves health and survival of mice on a high-calorie diet | Q27860950 | ||
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Reduced glycogen availability is associated with increased AMPKalpha2 activity, nuclear AMPKalpha2 protein abundance, and GLUT4 mRNA expression in contracting human skeletal muscle | Q64377743 | ||
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Muscle alpha-aminoisobutyric acid transport after exercise: enhanced stimulation by insulin | Q69891429 | ||
A common bicyclic protein kinase cascade inactivates the regulatory enzymes of fatty acid and cholesterol biosynthesis | Q69907652 | ||
Treadmill training improves intravenous glucose tolerance and insulin sensitivity in fatty Zucker rats | Q70253641 | ||
Effect of physical exercise on sensitivity and responsiveness to insulin in humans | Q70380200 | ||
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Impairment of peripheral glucose utilization in normal subjects by prolonged bed rest | Q71477066 | ||
Changes in physical fitness and all-cause mortality. A prospective study of healthy and unhealthy men | Q72135115 | ||
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AMP-activated protein kinase phosphorylation of endothelial NO synthase | Q74456171 | ||
Malonyl CoA as a metabolic switch and a regulator of insulin sensitivity | Q77440830 | ||
Liver AMP-activated protein kinase and acetyl-CoA carboxylase during and after exercise | Q77945919 | ||
Predominant alpha2/beta2/gamma3 AMPK activation during exercise in human skeletal muscle | Q79233726 | ||
Ca2+/calmodulin-dependent protein kinase kinase-alpha regulates skeletal muscle glucose uptake independent of AMP-activated protein kinase and Akt activation | Q79743582 | ||
Does the metabolic syndrome exist? | Q79793016 | ||
Distinct signals regulate AS160 phosphorylation in response to insulin, AICAR, and contraction in mouse skeletal muscle | Q79801118 | ||
Effect of sex differences on human MEF2 regulation during endurance exercise | Q80097640 | ||
Why muscle stops building when it's working | Q81321809 | ||
Exercise-Induced Phosphorylation of the Novel Akt Substrates AS160 and Filamin A in Human Skeletal Muscle | Q58449848 | ||
Functional role of AMP-activated protein kinase in the heart during exercise | Q59607761 | ||
Effects of experimental type 1 diabetes and exercise training on angiogenic gene expression and capillarization in skeletal muscle | Q60727708 | ||
Lack of AMPKα2 enhances pyruvate dehydrogenase activity during exercise | Q64018947 | ||
Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance | Q28186874 | ||
A role for AMP-activated protein kinase in contraction- and hypoxia-regulated glucose transport in skeletal muscle | Q28199222 | ||
5'-AMP-activated protein kinase activity and subunit expression in exercise-trained human skeletal muscle | Q28208928 | ||
Dissociation of AMPK activity and ACCbeta phosphorylation in human muscle during prolonged exercise | Q28212929 | ||
Activation of AMP-activated protein kinase leads to the phosphorylation of elongation factor 2 and an inhibition of protein synthesis | Q28218978 | ||
AMP-activated protein kinase plays a role in the control of food intake | Q28240521 | ||
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus | Q28254114 | ||
What makes vessels grow with exercise training? | Q28279253 | ||
The effects of increasing exercise intensity on muscle fuel utilisation in humans | Q28360649 | ||
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase | Q28567006 | ||
Adrenaline is a critical mediator of acute exercise-induced AMP-activated protein kinase activation in adipocytes | Q28570462 | ||
Coordinate regulation of malonyl-CoA decarboxylase, sn-glycerol-3-phosphate acyltransferase, and acetyl-CoA carboxylase by AMP-activated protein kinase in rat tissues in response to exercise | Q28581480 | ||
Myocardial ischemia and increased heart work modulate the phosphorylation state of eukaryotic elongation factor-2 | Q28582345 | ||
SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis | Q28583941 | ||
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade | Q28610414 | ||
Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms | Q28646530 | ||
Calorie restriction increases muscle mitochondrial biogenesis in healthy humans | Q28763406 | ||
Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). UK Prospective Diabetes Study (UKPDS) Group | Q29547282 | ||
Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study | Q29615122 | ||
Sirtuins in mammals: insights into their biological function | Q29615248 | ||
Metformin and reduced risk of cancer in diabetic patients | Q29616275 | ||
AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism | Q29617261 | ||
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy | Q29618101 | ||
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha | Q29620443 | ||
AMPK alpha1 activation is required for stimulation of glucose uptake by twitch contraction, but not by H2O2, in mouse skeletal muscle | Q33332145 | ||
Effect of acute exercise on AMPK signaling in skeletal muscle of subjects with type 2 diabetes: a time-course and dose-response study | Q33747784 | ||
Deficiency of LKB1 in skeletal muscle prevents AMPK activation and glucose uptake during contraction | Q33841869 | ||
Chronic activation of 5'-AMP-activated protein kinase increases GLUT-4, hexokinase, and glycogen in muscle | Q33880419 | ||
Activation of AMP-activated protein kinase increases mitochondrial enzymes in skeletal muscle | Q33905083 | ||
Analysis of the role of the AMP-activated protein kinase in the response to cellular stress. | Q33979128 | ||
Effect of rosiglitazone on the frequency of diabetes in patients with impaired glucose tolerance or impaired fasting glucose: a randomised controlled trial | Q33999757 | ||
Protein and amino acid metabolism during and after exercise and the effects of nutrition. | Q34001489 | ||
Effect of physical activity on cognitive function in older adults at risk for Alzheimer disease: a randomized trial | Q34013637 | ||
Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle. | Q34100394 | ||
Lipotoxic diseases | Q34111950 | ||
Functions of AMP-activated protein kinase in adipose tissue. | Q36482345 | ||
Short-term exercise in aged Tg2576 mice alters neuroinflammation and improves cognition | Q36662190 | ||
Interleukin-6 regulation of AMP-activated protein kinase. Potential role in the systemic response to exercise and prevention of the metabolic syndrome | Q36666161 | ||
Effects of acute exercise and training on insulin action and sensitivity: focus on molecular mechanisms in muscle | Q36673063 | ||
AMP-activated protein kinase is activated as a consequence of lipolysis in the adipocyte: potential mechanism and physiological relevance | Q36711158 | ||
The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial | Q36825706 | ||
Capitalizing on cortical plasticity: influence of physical activity on cognition and brain function | Q36880678 | ||
Activity-dependent signaling pathways controlling muscle diversity and plasticity | Q36910755 | ||
Ablation of AMP-activated protein kinase alpha2 activity exacerbates insulin resistance induced by high-fat feeding of mice | Q36943709 | ||
Role of AMP-activated protein kinase in the metabolic syndrome and in heart disease. | Q37005641 | ||
Contraction-stimulated glucose transport in rat skeletal muscle is sustained despite reversal of increased PAS-phosphorylation of AS160 and TBC1D1 | Q37033515 | ||
Systemic and mitochondrial adaptive responses to moderate exercise in rodents | Q37055818 | ||
LKB1 and AMPK in cell polarity and division | Q37100013 | ||
Physical activity and cancer prevention : pathways and targets for intervention | Q37112886 | ||
5-Aminoimidazole-4-carboxamide ribonucleoside treatment improves glucose homeostasis in insulin-resistant diabetic (ob/ob) mice | Q38292086 | ||
Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways | Q38316513 | ||
Mice lacking adiponectin show decreased hepatic insulin sensitivity and reduced responsiveness to peroxisome proliferator-activated receptor gamma agonists | Q38318111 | ||
Structural basis for glycogen recognition by AMP-activated protein kinase | Q38320088 | ||
Leptinomimetic effects of the AMP kinase activator AICAR in leptin-resistant rats: prevention of diabetes and ectopic lipid deposition. | Q38333574 | ||
Regulation of multisite phosphorylation and 14-3-3 binding of AS160 in response to IGF-1, EGF, PMA and AICAR. | Q39252731 | ||
Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle. | Q39646969 | ||
Decrease in Akt/PKB signalling in human skeletal muscle by resistance exercise | Q39974546 | ||
SIRT1 regulates hepatocyte lipid metabolism through activating AMP-activated protein kinase | Q39981968 | ||
Adaptations of skeletal muscle to endurance exercise and their metabolic consequences | Q40178125 | ||
Polyphenols stimulate AMP-activated protein kinase, lower lipids, and inhibit accelerated atherosclerosis in diabetic LDL receptor-deficient mice | Q40250591 | ||
Muscle glucose metabolism following exercise in the rat: increased sensitivity to insulin | Q40680853 | ||
SIRT1 controls endothelial angiogenic functions during vascular growth | Q41112118 | ||
Investigating the mechanism for AMP activation of the AMP-activated protein kinase cascade | Q42160057 | ||
Interleukin-6 stimulates lipolysis and fat oxidation in humans | Q42169595 | ||
AMP-activated protein kinase mediates VEGF-stimulated endothelial NO production | Q42269153 | ||
The 5'-AMP-activated protein kinase gamma3 isoform has a key role in carbohydrate and lipid metabolism in glycolytic skeletal muscle | Q42464408 | ||
AMP-activated kinase reciprocally regulates triacylglycerol synthesis and fatty acid oxidation in liver and muscle: evidence that sn-glycerol-3-phosphate acyltransferase is a novel target. | Q42468549 | ||
Exercise induces isoform-specific increase in 5'AMP-activated protein kinase activity in human skeletal muscle. | Q42490447 | ||
Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects | Q42498869 | ||
Role of AMPKalpha2 in basal, training-, and AICAR-induced GLUT4, hexokinase II, and mitochondrial protein expression in mouse muscle | Q42500929 | ||
A null mutation in skeletal muscle FAT/CD36 reveals its essential role in insulin- and AICAR-stimulated fatty acid metabolism | Q42507613 | ||
AMPK-mediated increase in myocardial long-chain fatty acid uptake critically depends on sarcolemmal CD36. | Q42508162 | ||
Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA)-riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle | Q42516404 | ||
Skeletal muscle malonyl-CoA content at the onset of exercise at varying power outputs in humans. | Q42542026 | ||
Human skeletal muscle malonyl-CoA at rest and during prolonged submaximal exercise | Q42556342 | ||
Evidence for the regulation of contraction-induced fatty acid oxidation via extracellular signal-regulated kinase 1/2 activation independent of changes in fatty acid uptake | Q42628963 | ||
Regulation of HSL serine phosphorylation in skeletal muscle and adipose tissue | Q42809801 | ||
AMP-activated protein kinase activity and glucose uptake in rat skeletal muscle | Q43565211 | ||
Dysfunctional regulation of endothelial nitric oxide synthase (eNOS) expression in response to exercise in mice lacking one eNOS gene | Q43636915 | ||
Activation of AMP kinase enhances sensitivity of muscle glucose transport to insulin | Q43819485 | ||
Skeletal muscle eEF2 and 4EBP1 phosphorylation during endurance exercise is dependent on intensity and muscle fiber type | Q43827533 | ||
Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes | Q43833528 | ||
Interleukin-6-deficient mice develop mature-onset obesity | Q43851625 | ||
Myocellular triacylglycerol breakdown in females but not in males during exercise | Q43879200 | ||
Progressive increase in human skeletal muscle AMPKalpha2 activity and ACC phosphorylation during exercise | Q43879217 | ||
Long-term AICAR administration reduces metabolic disturbances and lowers blood pressure in rats displaying features of the insulin resistance syndrome | Q44043225 | ||
Cardiorespiratory fitness as a predictor of cancer mortality among men with pre-diabetes and diabetes | Q44044328 | ||
AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats | Q44155454 | ||
Regulation of 5'AMP-activated protein kinase activity and substrate utilization in exercising human skeletal muscle | Q44253307 | ||
5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes | Q44418692 | ||
Physiological role of AMP-activated protein kinase in the heart: graded activation during exercise | Q44448758 | ||
Direct activation of AMP-activated protein kinase stimulates nitric-oxide synthesis in human aortic endothelial cells | Q44468960 | ||
AMPK activation increases uncoupling protein-3 expression and mitochondrial enzyme activities in rat muscle without fibre type transitions | Q44482243 | ||
Effect of exercise intensity on skeletal muscle AMPK signaling in humans | Q44564007 | ||
Knockout of the alpha2 but not alpha1 5'-AMP-activated protein kinase isoform abolishes 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranosidebut not contraction-induced glucose uptake in skeletal muscle. | Q44628501 | ||
Exercise training blunts microvascular rarefaction in the metabolic syndrome. | Q44921311 | ||
Muscle-derived interleukin-6: mechanisms for activation and possible biological roles | Q34146938 | ||
Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation | Q34183649 | ||
A novel domain in AMP-activated protein kinase causes glycogen storage bodies similar to those seen in hereditary cardiac arrhythmias. | Q34196949 | ||
Management of cellular energy by the AMP-activated protein kinase system | Q34209246 | ||
Insulin and glucose responses during bed rest with isotonic and isometric exercise | Q34244665 | ||
AMPK activity and isoform protein expression are similar in muscle of obese subjects with and without type 2 diabetes | Q34268235 | ||
5'-AMP-activated protein kinase activity and protein expression are regulated by endurance training in human skeletal muscle | Q34276280 | ||
AMP kinase and malonyl-CoA: targets for therapy of the metabolic syndrome | Q34310675 | ||
Activity of LKB1 and AMPK-related kinases in skeletal muscle: effects of contraction, phenformin, and AICAR. | Q34311558 | ||
AMP-activated protein kinase signaling stimulates VEGF expression and angiogenesis in skeletal muscle | Q34406367 | ||
AMP-activated protein kinase kinase activity and phosphorylation of AMP-activated protein kinase in contracting muscle of sedentary and endurance-trained rats. | Q34422776 | ||
Ca2+/calmodulin-dependent protein kinase kinase-beta acts upstream of AMP-activated protein kinase in mammalian cells. | Q34438345 | ||
AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle | Q34452979 | ||
Exercise training decreases the concentration of malonyl-CoA and increases the expression and activity of malonyl-CoA decarboxylase in human muscle | Q34487740 | ||
Walking compared with vigorous physical activity and risk of type 2 diabetes in women: a prospective study | Q34505481 | ||
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction | Q34534198 | ||
Skeletal muscle and heart LKB1 deficiency causes decreased voluntary running and reduced muscle mitochondrial marker enzyme expression in mice | Q34559719 | ||
AS160 phosphorylation is associated with activation of alpha2beta2gamma1- but not alpha2beta2gamma3-AMPK trimeric complex in skeletal muscle during exercise in humans | Q34578245 | ||
Skeletal muscle adaptation to exercise training: AMP-activated protein kinase mediates muscle fiber type shift | Q34629944 | ||
Invited review: effect of acute exercise on insulin signaling and action in humans | Q34691758 | ||
Selective suppression of AMP-activated protein kinase in skeletal muscle: update on 'lazy mice'. | Q35053068 | ||
Adiponectin stimulates angiogenesis by promoting cross-talk between AMP-activated protein kinase and Akt signaling in endothelial cells | Q35218922 | ||
An in vivo correlate of exercise-induced neurogenesis in the adult dentate gyrus | Q35720477 | ||
Resveratrol stimulates AMP kinase activity in neurons | Q35758555 | ||
A pivotal role for endogenous TGF-beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway | Q35768634 | ||
SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase | Q35990346 | ||
AMPK, the metabolic syndrome and cancer | Q36024356 | ||
Skeletal muscle glucose uptake during exercise: how is it regulated? | Q36197831 | ||
Physical inactivity is a disease | Q36252878 | ||
Neuronal protection by sirtuins in Alzheimer's disease | Q36283826 | ||
Obesity and the role of adipose tissue in inflammation and metabolism | Q36392619 | ||
Activation of AMP-activated protein kinase in the liver: a new strategy for the management of metabolic hepatic disorders | Q36462591 | ||
Neurobiology of exercise | Q36464136 | ||
Role of AMPK in skeletal muscle metabolic regulation and adaptation in relation to exercise | Q36475851 | ||
AMPK activity is diminished in tissues of IL-6 knockout mice: the effect of exercise | Q44953597 | ||
Regulation of hormone-sensitive lipase activity and Ser563 and Ser565 phosphorylation in human skeletal muscle during exercise. | Q45016706 | ||
Induced adiposity and adipocyte hypertrophy in mice lacking the AMP-activated protein kinase-alpha2 subunit | Q45032346 | ||
AMP-activated protein kinase is not down-regulated in human skeletal muscle of obese females | Q45050639 | ||
Malonyl-CoA and carnitine in regulation of fat oxidation in human skeletal muscle during exercise | Q45071070 | ||
The alpha2-5'AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading. | Q45161288 | ||
Exercise in rats does not alter hypothalamic AMP-activated protein kinase activity | Q45287352 | ||
Physical fitness and all-cause mortality. A prospective study of healthy men and women | Q45817114 | ||
AMPK-independent pathways regulate skeletal muscle fatty acid oxidation. | Q45915520 | ||
The alpha-subunit of AMPK is essential for submaximal contraction-mediated glucose transport in skeletal muscle in vitro | Q46350761 | ||
Long-term AICAR administration and exercise prevents diabetes in ZDF rats | Q46406504 | ||
Effects of alpha-AMPK knockout on exercise-induced gene activation in mouse skeletal muscle. | Q46477223 | ||
Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase. | Q46495742 | ||
Endurance exercise increases the SIRT1 and peroxisome proliferator-activated receptor gamma coactivator-1alpha protein expressions in rat skeletal muscle | Q46538551 | ||
Evidence for the involvement of CaMKII and AMPK in Ca2+-dependent signaling pathways regulating FA uptake and oxidation in contracting rodent muscle | Q46543180 | ||
Metabolic responses to reduced daily steps in healthy nonexercising men. | Q46694928 | ||
AMP-activated protein kinase alpha2 activity is not essential for contraction- and hyperosmolarity-induced glucose transport in skeletal muscle | Q46722194 | ||
Contraction-mediated phosphorylation of AMPK is lower in skeletal muscle of adenylate kinase-deficient mice | Q46728828 | ||
Nutritional status, cognition, and survival: a new role for leptin and AMP kinase | Q46734993 | ||
Increased malonyl-CoA and diacylglycerol content and reduced AMPK activity accompany insulin resistance induced by glucose infusion in muscle and liver of rats | Q46761363 | ||
Insulin-resistant muscle is exercise resistant: evidence for reduced response of nuclear-encoded mitochondrial genes to exercise | Q46817331 | ||
Exercise training promotes SIRT1 activity in aged rats. | Q46857793 | ||
Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin | Q46917157 | ||
Absence of humoral mediated 5'AMP-activated protein kinase activation in human skeletal muscle and adipose tissue during exercise. | Q46930517 | ||
Seven days of bed rest decrease insulin action on glucose uptake in leg and whole body | Q46970750 | ||
Effect of weight loss on muscle fiber type, fiber size, capillarity, and succinate dehydrogenase activity in humans | Q47253321 | ||
Interleukin-6 release from human skeletal muscle during exercise: relation to AMPK activity. | Q47668219 | ||
Reduced exercise endurance in interleukin-6-deficient mice | Q48013970 | ||
Exercise improves insulin and leptin sensitivity in hypothalamus of Wistar rats | Q48435774 | ||
Exercise enhances insulin and leptin signaling in the cerebral cortex and hypothalamus during dexamethasone-induced stress in diabetic rats | Q48524791 | ||
Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle | Q48546278 | ||
Dissecting the role of 5'-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase | Q50337120 | ||
Role of AMP-activated protein kinase in exercise capacity, whole body glucose homeostasis, and glucose transport in skeletal muscle -insight from analysis of a transgenic mouse model-. | Q51756025 | ||
AS160 regulates insulin- and contraction-stimulated glucose uptake in mouse skeletal muscle. | Q52573139 | ||
Resveratrol abolishes resistance to axonal degeneration in slow Wallerian degeneration (WldS) mice: activation of SIRT2, an NAD-dependent tubulin deacetylase. | Q53547602 | ||
Resistance exercise increases AMPK activity and reduces 4E-BP1 phosphorylation and protein synthesis in human skeletal muscle. | Q53608576 | ||
Insulin action on muscle protein kinetics and amino acid transport during recovery after resistance exercise. | Q54095949 | ||
Long-term exercise stimulates adenosine monophosphate-activated protein kinase activity and subunit expression in rat visceral adipose tissue and liver. | Q54592325 | ||
AMPK-Mediated AS160 Phosphorylation in Skeletal Muscle Is Dependent on AMPK Catalytic and Regulatory Subunits | Q57274206 | ||
Activation of Malonyl-CoA Decarboxylase in Rat Skeletal Muscle by Contraction and the AMP-activated Protein Kinase Activator 5-Aminoimidazole-4-carboxamide-1-β-d-ribofuranoside | Q58088416 | ||
Exercise diminishes the activity of acetyl-CoA carboxylase in human muscle | Q58108348 | ||
Caffeine-induced Ca2+ release increases AMPK-dependent glucose uptake in rodent soleus muscle | Q58172060 | ||
Exercise improves phosphatidylinositol-3,4,5-trisphosphate responsiveness of atypical protein kinase C and interacts with insulin signalling to peptide elongation in human skeletal muscle | Q58172078 | ||
Muscle metabolism during graded quadriceps exercise in man | Q58172093 | ||
Possible CaMKK-dependent regulation of AMPK phosphorylation and glucose uptake at the onset of mild tetanic skeletal muscle contraction | Q58172102 | ||
Higher skeletal muscle alpha2AMPK activation and lower energy charge and fat oxidation in men than in women during submaximal exercise | Q58172137 | ||
Exercise rapidly increases eukaryotic elongation factor 2 phosphorylation in skeletal muscle of men | Q58172158 | ||
IMP metabolism in human skeletal muscle after exhaustive exercise | Q58172456 | ||
Effect of exercise on insulin action in human skeletal muscle | Q58172564 | ||
P433 | issue | 2 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 261-275 | |
P577 | publication date | 2009-03-01 | |
P1433 | published in | Biochemical Journal | Q864221 |
P1476 | title | AMPK and the biochemistry of exercise: implications for human health and disease | |
P478 | volume | 418 |
Q51596146 | 5'-AMP activated protein kinase α2 controls substrate metabolism during post-exercise recovery via regulation of pyruvate dehydrogenase kinase 4. |
Q41508406 | 5'-AMP-activated protein kinase activity is elevated early during primary brain tumor development in the rat. |
Q50478355 | A Tbc1d1 Ser231Ala-knockin mutation partially impairs AICAR- but not exercise-induced muscle glucose uptake in mice. |
Q36815297 | A high-fat diet decreases AMPK activity in multiple tissues in the absence of hyperglycemia or systemic inflammation in rats |
Q91776028 | A muscle-specific UBE2O/AMPKα2 axis promotes insulin resistance and metabolic syndrome in obesity |
Q38977667 | A novel LKB1 isoform enhances AMPK metabolic activity and displays oncogenic properties. |
Q34381237 | A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity |
Q33688657 | AMP-activated Protein Kinase (AMPK): Does This Master Regulator of Cellular Energy State Distinguish Insulin Sensitive from Insulin Resistant Obesity? |
Q35229081 | AMP-activated protein kinase (AMPK) beta1beta2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise. |
Q36756228 | AMP-activated protein kinase and its downstream transcriptional pathways |
Q37856788 | AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan |
Q28480896 | AMP-activated protein kinase plays an important evolutionary conserved role in the regulation of glucose metabolism in fish skeletal muscle cells |
Q24610297 | AMP-activated protein kinase, stress responses and cardiovascular diseases |
Q33824564 | AMPK activation: a therapeutic target for type 2 diabetes? |
Q33783499 | AMPK and SIRT1: a long-standing partnership? |
Q34720569 | AMPK and insulin action--responses to ageing and high fat diet |
Q33789079 | AMPK as a metabolic tumor suppressor: control of metabolism and cell growth |
Q37657974 | AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice |
Q36966839 | AMPK, insulin resistance, and the metabolic syndrome |
Q33874648 | Abdominal obesity: causal factor or simply a symptom of obesity-related health risk |
Q27310085 | Abnormalities of AMPK activation and glucose uptake in cultured skeletal muscle cells from individuals with chronic fatigue syndrome |
Q38549546 | Activation of AMPK and its Impact on Exercise Capacity |
Q28482314 | Acute activation of AMP-activated protein kinase prevents H2O2-induced premature senescence in primary human keratinocytes |
Q36178191 | Angiotensin II regulates activation of Bim via Rb/E2F1 during apoptosis: involvement of interaction between AMPKβ1/2 and Cdk4. |
Q93048487 | Antioxidant and Adaptative Response Mediated by Nrf2 during Physical Exercise |
Q42475257 | Autophagic adaptation is associated with exercise-induced fibre-type shifting in skeletal muscle. |
Q26772690 | Barth Syndrome: From Mitochondrial Dysfunctions Associated with Aberrant Production of Reactive Oxygen Species to Pluripotent Stem Cell Studies |
Q43059644 | Cafeteria diet-induced insulin resistance is not associated with decreased insulin signaling or AMPK activity and is alleviated by physical training in rats |
Q54977465 | Capsaicinoids improve consequences of physical activity. |
Q37523452 | Chronic Exercise Training Improved Aortic Endothelial and Mitochondrial Function via an AMPKα2-Dependent Manner |
Q39435905 | Consequences of interrupted Rheb-to-AMPK feedback signaling in tuberous sclerosis complex and cancer |
Q64376771 | Contractile activity attenuates autophagy suppression and reverses mitochondrial defects in skeletal muscle cells |
Q37864394 | Control of nuclear receptor activities in metabolism by post-translational modifications |
Q28395897 | Creatine-kinase- and exercise-related muscle damage implications for muscle performance and recovery |
Q93155715 | Cyanate Induces Oxidative Stress Injury and Abnormal Lipid Metabolism in Liver through Nrf2/HO-1 |
Q47907358 | Cypermethrin Activates Autophagosome Formation Albeit Inhibits Autophagy Owing to Poor Lysosome Quality: Relevance to Parkinson's Disease |
Q46575557 | Decline of cell viability and mitochondrial activity in mouse skeletal muscle cell in a hypomagnetic field |
Q28070199 | Does Habitual Physical Activity Increase the Sensitivity of the Appetite Control System? A Systematic Review |
Q35757070 | Downregulation of AMPK accompanies leucine- and glucose-induced increases in protein synthesis and insulin resistance in rat skeletal muscle |
Q34567216 | Effect of Walking Exercise on Changes in Cardiorespiratory Fitness, Metabolic Syndrome Markers, and High-molecular-weight Adiponectin in Obese Middle-aged Women |
Q33506469 | Effect of exercise on disorders of carbohydrate and lipid metabolism in adults with traumatic spinal cord injury: systematic review of the evidence |
Q48044379 | Effects of 6-month aerobic interval training on skeletal muscle metabolism in middle-aged metabolic syndrome patients |
Q35910951 | Effects of Mung Bean (Vigna radiata L.) Ethanol Extracts Decrease Proinflammatory Cytokine-Induced Lipogenesis in the KK-Ay Diabese Mouse Model |
Q64778284 | Effects of Preventive Treadmill Exercise on the Recovery of Metabolic and Mitochondrial Factors in the 6-Hydroxydopamine Rat Model of Parkinson's Disease |
Q34525549 | Effects of exercise on AMPK signaling and downstream components to PI3K in rat with type 2 diabetes |
Q47237475 | Effects of topical capsaicin combined with moderate exercise on insulin resistance, body weight and oxidative stress in hypoestrogenic obese rats. |
Q33598389 | Electric pulse stimulation of cultured murine muscle cells reproduces gene expression changes of trained mouse muscle |
Q27307073 | Electrical pulse stimulation of cultured human skeletal muscle cells as an in vitro model of exercise |
Q58705798 | Endocrine Crosstalk Between Skeletal Muscle and the Brain |
Q35589856 | Endurance training inhibits insulin clearance and IDE expression in Swiss mice |
Q37629041 | Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662. |
Q36339569 | Exercise alleviates lipid-induced insulin resistance in human skeletal muscle-signaling interaction at the level of TBC1 domain family member 4. |
Q43239564 | Exercise and possible molecular mechanisms of protection from vascular disease and diabetes: the central role of ROS and nitric oxide |
Q99416008 | Exercise immunology: Future directions |
Q53266561 | Exercise type and volume alter signaling pathways regulating skeletal muscle glucose uptake and protein synthesis. |
Q92127887 | Exercise-Induced Mitohormesis for the Maintenance of Skeletal Muscle and Healthspan Extension |
Q54396964 | Exercise-induced expression of peroxisome proliferator-activated receptor γ coactivator-1α isoforms in skeletal muscle of endurance-trained males. |
Q38980340 | Exercise-stimulated glucose uptake - regulation and implications for glycaemic control |
Q43094322 | Exercising insulin sensitivity: AMPK turns on autophagy! |
Q57675707 | Extensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a 6-month exercise intervention |
Q37767671 | Fitness versus fatness: moving beyond weight loss in nonalcoholic fatty liver disease. |
Q87447906 | Forkhead BoxO transcription factors restrain exercise-induced angiogenesis |
Q42801551 | Formononetin, an isoflavone, activates AMP-activated protein kinase/β-catenin signalling to inhibit adipogenesis and rescues C57BL/6 mice from high-fat diet-induced obesity and bone loss. |
Q37198711 | Frequent interruptions of sedentary time modulates contraction- and insulin-stimulated glucose uptake pathways in muscle: Ancillary analysis from randomized clinical trials. |
Q39223093 | From apelin to exercise: emerging therapies for management of hypertension in pregnancy |
Q36253720 | Global Phosphoproteomic Analysis of Human Skeletal Muscle Reveals a Network of Exercise-Regulated Kinases and AMPK Substrates. |
Q51722308 | Globular adiponectin controls insulin-mediated vasoreactivity in muscle through AMPKα2. |
Q37095413 | Glycogen and its metabolism: some new developments and old themes |
Q54250681 | Greater basal skeletal muscle AMPKα phosphorylation in men than in women: Associations with anaerobic performance. |
Q42117438 | Hepatic energy state is regulated by glucagon receptor signaling in mice |
Q98613061 | High intensity exercise downregulates FTO mRNA expression during the early stages of recovery in young males and females |
Q55068293 | Human muscle fibre type-specific regulation of AMPK and downstream targets by exercise. |
Q42245821 | IL-6 indirectly modulates the induction of glyceroneogenic enzymes in adipose tissue during exercise |
Q56240296 | IL-6 regulates exercise and training-induced adaptations in subcutaneous adipose tissue in mice |
Q91639058 | Icariin treatment reduces blood glucose levels in type 2 diabetic rats and protects pancreatic function |
Q52841559 | Individual variability in compensatory eating following acute exercise in overweight and obese women. |
Q26777620 | Inflammation and intracellular metabolism: new targets in OA |
Q36795983 | LKB1 regulates lipid oxidation during exercise independently of AMPK |
Q34560916 | Lack of exercise is a major cause of chronic diseases |
Q34448802 | Lipid-induced insulin resistance affects women less than men and is not accompanied by inflammation or impaired proximal insulin signaling |
Q41885927 | Liver-specific ATP-citrate lyase inhibition by bempedoic acid decreases LDL-C and attenuates atherosclerosis |
Q91790804 | Long-Term Moderate Exercise Combined with Metformin Treatment Induces an Hormetic Response That Prevents Strength and Muscle Mass Loss in Old Female Wistar Rats |
Q24617747 | Metformin activates AMP kinase through inhibition of AMP deaminase |
Q90477678 | Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults |
Q54508172 | Metformin interacts with AMPK through binding to γ subunit. |
Q43063833 | Metformin, cancer, alphabet soup, and the role of epidemiology in etiologic research |
Q99414054 | Microbiota-Mitochondria Inter-Talk: A Potential Therapeutic Strategy in Obesity and Type 2 Diabetes |
Q36320932 | Mitochondrial antioxidative capacity regulates muscle glucose uptake in the conscious mouse: effect of exercise and diet |
Q59132572 | Mitochondrial targeting as a novel therapy for stroke |
Q98947491 | Molecular mechanisms involved in the positive effects of physical activity on coping with COVID-19 |
Q38111713 | Molecular mechanisms of muscle plasticity with exercise |
Q38549528 | Multi-target drugs to address multiple checkpoints in complex inflammatory pathologies: evolutionary cues for novel "first-in-class" anti-inflammatory drug candidates: a reviewer's perspective. |
Q45930153 | Multiple signalling pathways redundantly control glucose transporter GLUT4 gene transcription in skeletal muscle. |
Q38730157 | Muscle carnitine availability plays a central role in regulating fuel metabolism in the rodent |
Q45968038 | Muscle injury, impaired muscle function and insulin resistance in Chromogranin A-knockout mice. |
Q38095853 | Nitric oxide and energy metabolism in mammals |
Q54217434 | No effect of dietary nitrate supplementation on endurance training in hypoxia. |
Q37528136 | Novel pharmacological approaches to combat obesity and insulin resistance: targeting skeletal muscle with 'exercise mimetics'. |
Q34030453 | PGC-1α and exercise in the control of body weight. |
Q36674635 | PKD1 Inhibits AMPKα2 through Phosphorylation of Serine 491 and Impairs Insulin Signaling in Skeletal Muscle Cells |
Q51733417 | Performance during a strenuous swimming session is associated with high blood lactate: pyruvate ratio and hypoglycemia in fasted rats. |
Q36560523 | Perivascular adipose tissue control of insulin-induced vasoreactivity in muscle is impaired in db/db mice |
Q64097637 | Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver |
Q39117162 | Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle |
Q36702291 | Phosphatidylinositol-3,4,5-triphosphate and cellular signaling: implications for obesity and diabetes. |
Q34758958 | Physical activity recommendations, exercise intensity, and histological severity of nonalcoholic fatty liver disease |
Q36298471 | Plasma and adipose tissue level of angiopoietin-like 7 (ANGPTL7) are increased in obesity and reduced after physical exercise |
Q42794498 | Quantification of metformin by the HPLC method in brain regions, cerebrospinal fluid and plasma of rats treated with lipopolysaccharide |
Q55715015 | Quantitative proteomic characterization of cellular pathways associated with altered insulin sensitivity in skeletal muscle following high-fat diet feeding and exercise training. |
Q34460342 | Regular exercise is associated with a reduction in the risk of NAFLD and decreased liver enzymes in individuals with NAFLD independent of obesity in Korean adults |
Q37978302 | Regulation and limitations to fatty acid oxidation during exercise |
Q37697191 | Regulation of skeletal muscle cell plasticity by the peroxisome proliferator-activated receptor γ coactivator 1α. |
Q41061610 | Research of influence and mechanism of combining exercise with diet control on a model of lipid metabolism rat induced by high fat diet |
Q37679183 | Resistance training to improve type 2 diabetes: working toward a prescription for the future |
Q50482344 | Role of exercise duration on metabolic adaptations in working muscle to short-term moderate-to-heavy aerobic-based cycle training. |
Q33862222 | Role of exercise in maintaining the integrity of the neuromuscular junction |
Q27000731 | Role of lipotoxicity in endothelial dysfunction |
Q38128640 | Role of stearoyl-CoA desaturase-1 in skeletal muscle function and metabolism |
Q37815730 | SIRT1 and AMPK in regulating mammalian senescence: a critical review and a working model |
Q48002642 | SIRT6 regulates metabolic homeostasis in skeletal muscle through activation of AMPK. |
Q35192248 | Single muscle fiber proteomics reveals unexpected mitochondrial specialization |
Q41057061 | Sirt6 alters adult hippocampal neurogenesis |
Q60951291 | Skeletal Muscle Mitochondrial Protein Synthesis and Respiration Increase With Low-Load Blood Flow Restricted as Well as High-Load Resistance Training |
Q40967296 | Skeletal muscle AMPK is essential for the maintenance of FNDC5 expression |
Q27680957 | Structural basis of AMPK regulation by small molecule activators |
Q34100394 | Sucrose nonfermenting AMPK-related kinase (SNARK) mediates contraction-stimulated glucose transport in mouse skeletal muscle. |
Q89959094 | Supplementing conjugated and non-conjugated L-methionine and acetate alters expression patterns of CSN2, proteins and metabolites related to protein synthesis in bovine mammary cells |
Q28584878 | Suppression of 5'-nucleotidase enzymes promotes AMP-activated protein kinase (AMPK) phosphorylation and metabolism in human and mouse skeletal muscle |
Q36171138 | Systems analysis of eleven rodent disease models reveals an inflammatome signature and key drivers |
Q42426461 | Tafazzin knockdown causes hypertrophy of neonatal ventricular myocytes |
Q38606849 | Targeting of cell metabolism in human acute myeloid leukemia--more than targeting of isocitrate dehydrogenase mutations and PI3K/AKT/mTOR signaling? |
Q36038197 | The AMPK activator R419 improves exercise capacity and skeletal muscle insulin sensitivity in obese mice. |
Q33705451 | The Crosstalk between the Gut Microbiota and Mitochondria during Exercise |
Q37337283 | The Randle cycle revisited: a new head for an old hat. |
Q51553127 | The effect of age and unilateral leg immobilization for 2 weeks on substrate utilization during moderate-intensity exercise in human skeletal muscle. |
Q34658544 | The many ways to regulate glucose transporter 4. |
Q37880062 | The relationship between substrate metabolism, exercise and appetite control: does glycogen availability influence the motivation to eat, energy intake or food choice? |
Q46978063 | The role of declining adaptive homeostasis in ageing |
Q43007275 | Thujone, a component of medicinal herbs, rescues palmitate-induced insulin resistance in skeletal muscle |
Q33899674 | Treadmill exercise ameliorates the regulation of energy metabolism in skeletal muscle of NSE/PS2m-transgenic mice with Alzheimer's disease |
Q26753111 | Understanding Muscle Dysfunction in Chronic Fatigue Syndrome |
Q90420426 | Understanding the Role of Dysfunctional and Healthy Mitochondria in Stroke Pathology and Its Treatment |
Q38810023 | Unraveling the actions of AMP-activated protein kinase in metabolic diseases: Systemic to molecular insights |
Q35146002 | Urocortin 3 transgenic mice exhibit a metabolically favourable phenotype resisting obesity and hyperglycaemia on a high-fat diet. |
Q30355011 | Voluntary Exercise Improves Estrous Cyclicity in Prenatally Androgenized Female Mice Despite Programming Decreased Voluntary Exercise: Implications for Polycystic Ovary Syndrome (PCOS). |
Q34333517 | Whole body deletion of AMP-activated protein kinase {beta}2 reduces muscle AMPK activity and exercise capacity. |
Q26824357 | You're only as old as your arteries: translational strategies for preserving vascular endothelial function with aging |
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