| scholarly article | Q13442814 |
| P2093 | author name string | Hong Zhao | |
| Stephen J Benkovic | |||
| Ye Fang | |||
| Jarrod B French | |||
| P2860 | cites work | Mthfs is an Essential Gene in Mice and a Component of the Purinosome | Q21131261 |
| Developments in the scientific and clinical understanding of gout | Q21195376 | ||
| AMP-Activated Protein Kinase in Metabolic Control and Insulin Signaling | Q22241925 | ||
| Hallmarks of Cancer: The Next Generation | Q22252312 | ||
| PYRIMIDINE AND PURINE BIOSYNTHESIS AND DEGRADATION IN PLANTS | Q22255665 | ||
| Protein Structures Forming the Shell of Primitive Bacterial Organelles | Q22299353 | ||
| DrugBank: a comprehensive resource for in silico drug discovery and exploration | Q24188653 | ||
| A census of human soluble protein complexes | Q24297808 | ||
| AICA-ribosiduria: a novel, neurologically devastating inborn error of purine biosynthesis caused by mutation of ATIC | Q24534042 | ||
| Identification of novel filament-forming proteins in Saccharomyces cerevisiae and Drosophila melanogaster | Q24627262 | ||
| The metabolic enzyme CTP synthase forms cytoskeletal filaments | Q24630587 | ||
| Microtubule-assisted mechanism for functional metabolic macromolecular complex formation | Q24633198 | ||
| Dynamic regulation of a metabolic multi-enzyme complex by protein kinase CK2 | Q24634071 | ||
| Enzymology of purine and pyrimidine antimetabolites used in the treatment of cancer | Q24642847 | ||
| The genetic design of signaling cascades to record receptor activation | Q24657333 | ||
| Uric acid, hyperuricemia and vascular diseases | Q26850727 | ||
| Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis | Q27631389 | ||
| Crystal structures of human GAR Tfase at low and high pH and with substrate beta-GAR | Q27640024 | ||
| Structural insights into the avian AICAR transformylase mechanism | Q27640238 | ||
| Octameric structure of the human bifunctional enzyme PAICS in purine biosynthesis | Q27643550 | ||
| Structure and mechanisms of a protein-based organelle in Escherichia coli | Q27658834 | ||
| Biochemical and Structural Characterization of a Ureidoglycine Aminotransferase in the Klebsiella pneumoniae Uric Acid Catabolic Pathway | Q27662527 | ||
| Structural studies of tri-functional human GART | Q27663462 | ||
| Serine is a natural ligand and allosteric activator of pyruvate kinase M2 | Q27674495 | ||
| Structural and Mechanistic Studies of HpxO, a Novel Flavin Adenine Dinucleotide-Dependent Urate Oxidase from Klebsiella pneumoniae | Q27675566 | ||
| Structure of the allosteric regulatory enzyme of purine biosynthesis | Q27731412 | ||
| Mechanism of the synergistic end-product regulation of Bacillus subtilis glutamine phosphoribosylpyrophosphate amidotransferase by nucleotides | Q27742427 | ||
| Widespread reorganization of metabolic enzymes into reversible assemblies upon nutrient starvation. | Q27933749 | ||
| A FAMILIAL DISORDER OF URIC ACID METABOLISM AND CENTRAL NERVOUS SYSTEM FUNCTION | Q28156382 | ||
| Anticancer Antifolates: Current Status and Future Directions | Q28207632 | ||
| An infantile autistic syndrome characterised by the presence of succinylpurines in body fluids | Q28261748 | ||
| The apo and ternary complex structures of a chemotherapeutic target: human glycinamide ribonucleotide transformylase | Q28262348 | ||
| Glutamine PRPP amidotransferase: snapshots of an enzyme in action | Q28294777 | ||
| Structure-based prediction of protein–protein interactions on a genome-wide scale | Q29012686 | ||
| AMPK: a nutrient and energy sensor that maintains energy homeostasis | Q29615410 | ||
| GPCRs regulate the assembly of a multienzyme complex for purine biosynthesis. | Q34054724 | ||
| Variations in purine metabolism of cultured skin fibroblasts from patients with gout | Q34277147 | ||
| Characterization of the enzyme complex involving the folate-requiring enzymes of de novo purine biosynthesis | Q34286888 | ||
| Investigation of the mechanism of phosphoribosylamine transfer from glutamine phosphoribosylpyrophosphate amidotransferase to glycinamide ribonucleotide synthetase | Q34293300 | ||
| Hsp70/Hsp90 chaperone machinery is involved in the assembly of the purinosome. | Q34325039 | ||
| Low-dose methotrexate: a mainstay in the treatment of rheumatoid arthritis | Q34421147 | ||
| Label-Free Receptor Assays | Q34473007 | ||
| Cancer's molecular sweet tooth and the Warburg effect. | Q34566915 | ||
| The purine synthesis gene Prat2 is required for Drosophila metamorphosis, as revealed by inverted-repeat-mediated RNA interference | Q34588058 | ||
| Reversible compartmentalization of de novo purine biosynthetic complexes in living cells | Q34767701 | ||
| Structural biology of the purine biosynthetic pathway | Q34810454 | ||
| Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast | Q35763361 | ||
| Disorders of purine and pyrimidine metabolism | Q36263825 | ||
| Pemetrexed: a multitargeted antifolate | Q36314336 | ||
| Mapping protein-protein proximity in the purinosome. | Q36332857 | ||
| Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation | Q36477750 | ||
| SAICAR stimulates pyruvate kinase isoform M2 and promotes cancer cell survival in glucose-limited conditions | Q36480143 | ||
| Purine and pyrimidine metabolism in Leishmania | Q37118742 | ||
| Folate and vitamin B12 metabolism: overview and interaction with riboflavin, vitamin B6, and polymorphisms | Q37246124 | ||
| Zebrafish mutations in gart and paics identify crucial roles for de novo purine synthesis in vertebrate pigmentation and ocular development. | Q37257838 | ||
| Inborn errors of purine and pyrimidine metabolism. | Q37416449 | ||
| Metabolism of inflammation limited by AMPK and pseudo-starvation | Q38074586 | ||
| Mutations of ATIC and ADSL affect purinosome assembly in cultured skin fibroblasts from patients with AICA-ribosiduria and ADSL deficiency | Q39425863 | ||
| ADA and PNP deficiencies: how it all began | Q39850207 | ||
| The biological significance of purine salvage | Q39894422 | ||
| Some regulatory and integrative aspects of purine nucleotide biosynthesis and its control: An overview | Q40097175 | ||
| Resonant waveguide grating biosensor for living cell sensing. | Q40269125 | ||
| Feedback inhibition of amidophosphoribosyltransferase regulates the rate of cell growth via purine nucleotide, DNA, and protein syntheses | Q40814444 | ||
| Amidophosphoribosyltransferase Limits the Rate of Cell Growth-linked de Novo Purine Biosynthesis in the Presence of Constant Capacity of Salvage Purine Biosynthesis | Q41099740 | ||
| Characterization and chemical properties of phosphoribosylamine, an unstable intermediate in the de novo purine biosynthetic pathway | Q41769956 | ||
| Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: cellular models of de novo purine biosynthesis deficiency disorders | Q41956655 | ||
| De novo GMP synthesis is required for axon guidance in Drosophila | Q42712825 | ||
| Folate-mediated one-carbon metabolism | Q46356485 | ||
| Enzymic capacities of purine de Novo and salvage pathways for nucleotide synthesis in normal and neoplastic tissues | Q48665468 | ||
| Synthesis de novo of purines in slices of rat brain and liver | Q48944264 | ||
| Evidence for direct inhibition of de novo purine synthesis in human MCF-7 breast cells as a principal mode of metabolic inhibition by methotrexate | Q69005371 | ||
| De novo purine synthesis in skeletal muscle | Q70270339 | ||
| Salvage capacity of hepatoma 3924A and action of dipyridamole | Q70520632 | ||
| Kinetic, physical, and regulatory properties of amidophosphoribosyltransferase | Q72661486 | ||
| Nucleic Acids, Purines, Pyrimidines (Nucleotide Synthesis) | Q78759814 | ||
| Signaling pathways: Purinosomes under GPCR control | Q82517989 | ||
| Adenosine-deaminase deficiency in two patients with severely impaired cellular immunity | Q93729850 | ||
| P433 | issue | 40 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 4444-4452 | |
| P577 | publication date | 2013-04-11 | |
| P1433 | published in | Chemical Communications | Q426303 |
| P1476 | title | The purinosome, a multi-protein complex involved in the de novo biosynthesis of purines in humans | |
| P478 | volume | 49 |
| Q58777653 | Beyond the Warburg Effect: How Do Cancer Cells Regulate One-Carbon Metabolism? |
| Q91794905 | Cell-Inspired All-Aqueous Microfluidics: From Intracellular Liquid-Liquid Phase Separation toward Advanced Biomaterials |
| Q90781379 | Combinatorial targeting of MTHFD2 and PAICS in purine synthesis as a novel therapeutic strategy |
| Q93058477 | Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation |
| Q38925460 | Dynamic architecture of the purinosome involved in human de novo purine biosynthesis |
| Q35596622 | Elements of the cellular metabolic structure |
| Q47553217 | Expression of the purine biosynthetic enzyme phosphoribosyl formylglycinamidine synthase (FGAMS) in neurons |
| Q35002908 | First evidence for substrate channeling between proline catabolic enzymes: a validation of domain fusion analysis for predicting protein-protein interactions. |
| Q35998332 | GMP synthase is essential for viability and infectivity of Trypanosoma brucei despite a redundant purine salvage pathway. |
| Q28080198 | Interplay of Murine Gammaherpesvirus 68 with NF-kappaB Signaling of the Host |
| Q89711408 | LRRK2 maintains mitochondrial homeostasis and regulates innate immune responses to Mycobacterium tuberculosis |
| Q93163796 | Liquid-liquid phase separation in artificial cells |
| Q37025025 | Metabolic regulation via enzyme filamentation |
| Q58742209 | Metabolomic profiling of human lung tumor tissues - nucleotide metabolism as a candidate for therapeutic interventions and biomarkers |
| Q90226364 | Microtubule-directed transport of purine metabolons drives their cytosolic transit to mitochondria |
| Q60300674 | Molecular comparison of Neanderthal and Modern Human adenylosuccinate lyase |
| Q36236446 | Partial Purification of a Megadalton DNA Replication Complex by Free Flow Electrophoresis |
| Q36744568 | Phototransduction Influences Metabolic Flux and Nucleotide Metabolism in Mouse Retina |
| Q35062843 | Purinosome formation as a function of the cell cycle |
| Q91986309 | RNA promotes phase separation of glycolysis enzymes into yeast G bodies in hypoxia |
| Q38335072 | Regulation of mammalian nucleotide metabolism and biosynthesis |
| Q47140464 | Sequestration-Mediated Downregulation of de Novo Purine Biosynthesis by AMPK. |
| Q38955873 | Serine and one-carbon metabolism in cancer |
| Q39350533 | Spatial Organization of Metabolic Enzyme Complexes in Cells |
| Q36939902 | Spatial colocalization and functional link of purinosomes with mitochondria. |
| Q38508406 | Subcellular functions of proteins under fluorescence single-cell microscopy |
| Q36313528 | The exocyclic amino group of adenine in PtII and PdII complexes: a critical comparison of the X-ray crystallographic structural data and gas phase calculations. |
| Q37620497 | Transcriptomic investigation of wound healing and regeneration in the cnidarian Calliactis polypus. |
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