| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | Andrew N Lane | |
| Teresa W-M Fan | |||
| P2860 | cites work | Distributions of exons and introns in the human genome | Q80241605 |
| Cellular volume and marker expression in human peripheral blood apheresis stem cells | Q80480517 | ||
| Modeling cancer glycolysis | Q82624228 | ||
| Determining and understanding the control of glycolysis in fast-growth tumor cells. Flux control by an over-expressed but strongly product-inhibited hexokinase | Q83204784 | ||
| Mitotic index of invasive breast carcinoma. Achieving clinically meaningful precision and evaluating tertial cutoffs | Q84839093 | ||
| Pathways from glutamine to apoptosis. | Q36486735 | ||
| Regulation of ribonucleotide reductase activity in mammalian cells | Q70284517 | ||
| Comparison of purine and pyrimidine metabolism in G1 and S phases of HeLa and Chinese hamster ovary cells | Q70423882 | ||
| Molecular oxygen modulates cytochrome c oxidase function | Q71245542 | ||
| Dual role for the glutamine phosphoribosylpyrophosphate amidotransferase ammonia channel. Interdomain signaling and intermediate channeling | Q73538434 | ||
| Oxythiamine and dehydroepiandrosterone inhibit the nonoxidative synthesis of ribose and tumor cell proliferation | Q73789734 | ||
| Effects of guanine nucleotide depletion on cell cycle progression in human T lymphocytes | Q74412879 | ||
| THE INTERSTITIAL FLUID OF SOLID TUMORS | Q76907818 | ||
| The molecular perspective: methotrexate | Q78220193 | ||
| Pervasive transcription of the human genome produces thousands of previously unidentified long intergenic noncoding RNAs | Q21144890 | ||
| Targeting aspartate aminotransferase in breast cancer | Q22000773 | ||
| On the immortality of television sets: "function" in the human genome according to the evolution-free gospel of ENCODE | Q22066047 | ||
| An integrated encyclopedia of DNA elements in the human genome | Q22122150 | ||
| HIF-2alpha promotes hypoxic cell proliferation by enhancing c-myc transcriptional activity | Q24302129 | ||
| HMDB 3.0--The Human Metabolome Database in 2013 | Q24595162 | ||
| Understanding the Warburg effect: the metabolic requirements of cell proliferation | Q24604760 | ||
| Stable isotope-resolved metabolomics and applications for drug development | Q24629149 | ||
| IMP dehydrogenase: structure, mechanism, and inhibition | Q24642299 | ||
| Brick by brick: metabolism and tumor cell growth | Q24656187 | ||
| Global mapping of c-Myc binding sites and target gene networks in human B cells | Q24675083 | ||
| Mice have a transcribed L-threonine aldolase/GLY1 gene, but the human GLY1 gene is a non-processed pseudogene | Q24806237 | ||
| Transcriptional repression of human cad gene by hypoxia inducible factor-1alpha | Q24814445 | ||
| c-Myc-regulated microRNAs modulate E2F1 expression | Q27861046 | ||
| Structural basis for the specificity, catalysis, and regulation of human uridine-cytidine kinase | Q28118733 | ||
| A ribonucleotide reductase gene is a transcriptional target of p53 and p73 | Q28138249 | ||
| A ribonucleotide reductase gene involved in a p53-dependent cell-cycle checkpoint for DNA damage | Q28138556 | ||
| Regulation of mammalian O2 homeostasis by hypoxia-inducible factor 1 | Q28141355 | ||
| Levels of hypoxia-inducible factor-1alpha independently predict prognosis in patients with lymph node negative breast carcinoma | Q28181979 | ||
| 5-Fluorouracil: mechanisms of action and clinical strategies | Q28201937 | ||
| Inhibitors of de novo nucleotide biosynthesis as drugs | Q28215220 | ||
| The control of flux | Q28237216 | ||
| Nuclear targeting of 6-phosphofructo-2-kinase (PFKFB3) increases proliferation via cyclin-dependent kinases | Q28246409 | ||
| Pharmacogenetics of thiopurine S-methyltransferase and thiopurine therapy | Q28269559 | ||
| c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells | Q28275988 | ||
| Isotopically nonstationary 13C flux analysis of Myc-induced metabolic reprogramming in B-cells. | Q36503881 | ||
| Ribonucleotide reductase association with mammalian liver mitochondria | Q36812510 | ||
| Gene expression of human DNA polymerase alpha during cell proliferation and the cell cycle | Q36849617 | ||
| Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. | Q36850905 | ||
| Adaptive landscapes and emergent phenotypes: why do cancers have high glycolysis? | Q36877059 | ||
| Hypoxic and Ras-transformed cells support growth by scavenging unsaturated fatty acids from lysophospholipids | Q36895786 | ||
| Prodrugs of nucleoside analogues for improved oral absorption and tissue targeting | Q36909036 | ||
| Rhabdomyosarcoma cells show an energy producing anabolic metabolic phenotype compared with primary myocytes. | Q36960665 | ||
| HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma | Q37052897 | ||
| Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development | Q37087191 | ||
| Regulation of purine biosynthesis and turnover | Q37159058 | ||
| Prospects for clinical cancer metabolomics using stable isotope tracers | Q37201287 | ||
| Altered regulation of metabolic pathways in human lung cancer discerned by (13)C stable isotope-resolved metabolomics (SIRM) | Q37281258 | ||
| The role of HIF prolyl hydroxylases in tumour growth. | Q37295254 | ||
| The purinosome, a multi-protein complex involved in the de novo biosynthesis of purines in humans | Q37424854 | ||
| c-Myc activates multiple metabolic networks to generate substrates for cell-cycle entry | Q37427003 | ||
| MYC-induced cancer cell energy metabolism and therapeutic opportunities | Q37438881 | ||
| Control of glutamine metabolism by the tumor suppressor Rb. | Q37571643 | ||
| Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cells | Q37577449 | ||
| Targeting metabolic transformation for cancer therapy. | Q37714309 | ||
| Skeletal muscle fatigue--regulation of excitation-contraction coupling to avoid metabolic catastrophe | Q38012959 | ||
| Fulfilling the metabolic requirements for cell proliferation | Q38029807 | ||
| Cancer cell metabolism: one hallmark, many faces. | Q38046274 | ||
| The human concentrative and equilibrative nucleoside transporter families, SLC28 and SLC29. | Q38090786 | ||
| Glycine metabolism in animals and humans: implications for nutrition and health | Q38101481 | ||
| Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases. | Q38110693 | ||
| The functional logic of cytosolic 5'-nucleotidases | Q38132866 | ||
| Poly(ADP-ribosyl)ation in regulation of chromatin structure and the DNA damage response | Q38155805 | ||
| NAD biosynthesis in humans--enzymes, metabolites and therapeutic aspects | Q38156477 | ||
| Cellular regulation of ribonucleotide reductase in eukaryotes | Q38202401 | ||
| The hepatocyte. Development, differentiation, and ageing | Q38213538 | ||
| Perinuclear Mitochondrial Clustering Creates an Oxidant-Rich Nuclear Domain Required for Hypoxia-Induced Transcription | Q38323862 | ||
| Protein and nucleotide biosynthesis are coupled by a single rate-limiting enzyme, PRPS2, to drive cancer | Q38992372 | ||
| Explaining the enigmatic KM for oxygen in cytochrome c oxidase: A kinetic model | Q51616888 | ||
| Metabolic control and compartmentation in single living cells | Q52707005 | ||
| Bioenergetics of human peripheral blood mononuclear cell metabolism in quiescent, activated, and glucocorticoid-treated states | Q52968093 | ||
| ATP-producing and consuming processes of Ehrlich mouse ascites tumor cells in proliferating and resting phases | Q53029816 | ||
| Serine, but not glycine, supports one-carbon metabolism and proliferation of cancer cells. | Q53052028 | ||
| Antisense glutaminase inhibition modifies the O-GlcNAc pattern and flux through the hexosamine pathway in breast cancer cells. | Q53542689 | ||
| Mechanism of the physiological reaction catalyzed by tryptophan synthase from Escherichia coli. | Q54701750 | ||
| The role of multiple enzyme activation in metabolic flux control | Q58744508 | ||
| Human IMP dehydrogenase. Kinetics and regulatory properties | Q68699786 | ||
| Human adenylosuccinate synthetase. Partial purification, kinetic and regulatory properties of the enzyme from placenta | Q68844246 | ||
| Metabolism of pyrimidine bases and nucleosides by pyrimidine-nucleoside phosphorylases in cultured human lymphoid cells | Q68983916 | ||
| Cell cycle-dependent expression of mammalian ribonucleotide reductase. Differential regulation of the two subunits | Q69900353 | ||
| Energy metabolism in tumor cells | Q28288377 | ||
| Chemistry in living systems | Q28291334 | ||
| Leflunomide: A Drug with a Potential Beyond Rheumatology | Q28294236 | ||
| Glutamine PRPP amidotransferase: snapshots of an enzyme in action | Q28294777 | ||
| The origin, evolution and proposed stabilization of the terms 'genome size' and 'C-value' to describe nuclear DNA contents | Q28298127 | ||
| HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia | Q28300406 | ||
| Regulation of cancer cell metabolism | Q28303890 | ||
| Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells | Q28504783 | ||
| Metabolic Reprogramming for Producing Energy and Reducing Power in Fumarate Hydratase Null Cells from Hereditary Leiomyomatosis Renal Cell Carcinoma | Q28535371 | ||
| Regulation of carbamoyl phosphate synthetase by MAP kinase | Q28578262 | ||
| The oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entry | Q28580062 | ||
| Revisiting and revising the purinosome | Q28656168 | ||
| The biology of cancer: metabolic reprogramming fuels cell growth and proliferation | Q29547301 | ||
| Landscape of transcription in human cells | Q29547467 | ||
| Aerobic glycolysis: meeting the metabolic requirements of cell proliferation | Q29615178 | ||
| Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction | Q29616653 | ||
| Physiological concentrations of purines and pyrimidines | Q29616721 | ||
| c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism | Q29617213 | ||
| Otto Warburg's contributions to current concepts of cancer metabolism | Q29617601 | ||
| Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis | Q29617613 | ||
| Ribonucleotide reductases | Q29620027 | ||
| An overview of cytidine deaminases | Q31041934 | ||
| Spatial heterogeneity and oxygen dependence of glucose consumption in R3230Ac and fibrosarcomas of the Fischer 344 rat. | Q33217203 | ||
| Global identification of Myc target genes reveals its direct role in mitochondrial biogenesis and its E-box usage in vivo | Q33323393 | ||
| Global regulation of nucleotide biosynthetic genes by c-Myc | Q33352002 | ||
| Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer | Q33604129 | ||
| Mass isotopomer distribution analysis at eight years: theoretical, analytic, and experimental considerations | Q33654282 | ||
| Modulation of RNA function by aminoglycoside antibiotics | Q33808338 | ||
| Alterations in the glycolytic and glutaminolytic pathways after malignant transformation of rat liver oval cells | Q33871773 | ||
| An introduction to the use of tracers in nutrition and metabolism | Q33902310 | ||
| Comparison of the electrophoretic and hydrodynamic properties of DNA and RNA oligonucleotide duplexes | Q33907436 | ||
| A novel deconvolution method for modeling UDP-N-acetyl-D-glucosamine biosynthetic pathways based on (13)C mass isotopologue profiles under non-steady-state conditions | Q33917561 | ||
| Quantitative flux analysis reveals folate-dependent NADPH production. | Q33924205 | ||
| Tracing compartmentalized NADPH metabolism in the cytosol and mitochondria of mammalian cells | Q33930109 | ||
| FTIR spectroscopy demonstrates biochemical differences in mammalian cell cultures at different growth stages | Q34182760 | ||
| Functional genomics reveal that the serine synthesis pathway is essential in breast cancer | Q34200610 | ||
| Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase | Q34208791 | ||
| The metabolic demands of cancer cells are coupled to their size and protein synthesis rates | Q34258905 | ||
| Glycolysis, glutaminolysis and cell proliferation | Q34268269 | ||
| Investigation of the mechanism of phosphoribosylamine transfer from glutamine phosphoribosylpyrophosphate amidotransferase to glycinamide ribonucleotide synthetase | Q34293300 | ||
| Transcriptional amplification in tumor cells with elevated c-Myc. | Q34302542 | ||
| Band 3/complement-mediated recognition and removal of normally senescent and pathological human erythrocytes | Q34469434 | ||
| Amino acid transport across mammalian intestinal and renal epithelia | Q34736025 | ||
| Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cells | Q34803825 | ||
| Direct measurement of oxygen consumption rates from attached and unattached cells in a reversibly sealed, diffusionally isolated sample chamber | Q34908778 | ||
| NMR-based stable isotope resolved metabolomics in systems biochemistry | Q34921472 | ||
| The molecular determinants of de novo nucleotide biosynthesis in cancer cells | Q34939794 | ||
| Pyruvate carboxylase is required for glutamine-independent growth of tumor cells | Q35008346 | ||
| Stable isotope resolved metabolomics of lung cancer in a SCID mouse model | Q35030808 | ||
| Stable Isotope-Resolved Metabolomics (SIRM) in Cancer Research with Clinical Application to NonSmall Cell Lung Cancer | Q35075007 | ||
| Stable isotope-labeled tracers for metabolic pathway elucidation by GC-MS and FT-MS. | Q35109445 | ||
| Metabolic pathways in the post-genome era. | Q35135595 | ||
| Long-term synthesis rates of skeletal muscle DNA and protein are higher during aerobic training in older humans than in sedentary young subjects but are not altered by protein supplementation | Q35169483 | ||
| Dependence of mouse embryonic stem cells on threonine catabolism | Q35216662 | ||
| Reduced Level of Ribonucleotide Reductase R2 Subunits Increases Dependence on Homologous Recombination Repair of Cisplatin-Induced DNA Damage | Q35586061 | ||
| Hypoxia promotes isocitrate dehydrogenase-dependent carboxylation of α-ketoglutarate to citrate to support cell growth and viability | Q35621293 | ||
| Molecular basis for the differential use of glucose and glutamine in cell proliferation as revealed by synchronized HeLa cells. | Q35641497 | ||
| Reductive carboxylation supports growth in tumour cells with defective mitochondria. | Q35683311 | ||
| Measurement of cell proliferation by labeling of DNA with stable isotope-labeled glucose: Studies in vitro , in animals, and in humans | Q35743125 | ||
| Mammalian pyrimidine biosynthesis: fresh insights into an ancient pathway | Q35750835 | ||
| The metabolic profile of tumors depends on both the responsible genetic lesion and tissue type. | Q35764439 | ||
| Stable Isotope Resolved Metabolomics Analysis of Ribonucleotide and RNA Metabolism in Human Lung Cancer Cells | Q35801072 | ||
| Ribosomal RNA processing and ribosome biogenesis in eukaryotes | Q35951083 | ||
| Reprogramming of proline and glutamine metabolism contributes to the proliferative and metabolic responses regulated by oncogenic transcription factor c-MYC | Q36061545 | ||
| Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease. | Q36087194 | ||
| Metabolism of [U‐13C]glucose in human brain tumors in vivo | Q36120642 | ||
| Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism | Q36319414 | ||
| Identification of cancer mechanisms through computational systems modeling | Q36357667 | ||
| Necrotic death as a cell fate | Q36359618 | ||
| Nucleoside salvage pathway kinases regulate hematopoiesis by linking nucleotide metabolism with replication stress | Q36408993 | ||
| Energy management by enhanced glycolysis in G1-phase in human colon cancer cells in vitro and in vivo | Q39143359 | ||
| Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling | Q39787798 | ||
| Glutamine metabolism in lymphocytes: its biochemical, physiological and clinical importance | Q39837919 | ||
| Quantitation of cellular deoxynucleoside triphosphates | Q39843396 | ||
| The phosphatidylinositol 3-kinase/akt cassette regulates purine nucleotide synthesis | Q39907104 | ||
| The pervasive presence of fluctuating oxygenation in tumors | Q39960720 | ||
| The oncoprotein H-RasV12 increases mitochondrial metabolism | Q40041752 | ||
| Isotopomer-based metabolomic analysis by NMR and mass spectrometry | Q40061257 | ||
| Mechanism of the Prolyl Hydroxylase Reaction. 2. Kinetic Analysis of the Reaction Sequence | Q40111392 | ||
| Phospholipids are synthesized in the G2/M phase of the cell cycle | Q40206751 | ||
| Pentose phosphate cycle oxidative and nonoxidative balance: A new vulnerable target for overcoming drug resistance in cancer | Q40223808 | ||
| Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells | Q40232298 | ||
| Decoding key nodes in the metabolism of cancer cells: sugar & spice and all things nice | Q40300001 | ||
| Gemcitabine: metabolism, mechanisms of action, and self-potentiation. | Q40371567 | ||
| 13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and gamma-glutamyl cycle activity in a clonal pancreatic beta-cell line. | Q40637734 | ||
| Cell cycle-dependent regulation of pyrimidine biosynthesis | Q40689222 | ||
| Contribution by different fuels and metabolic pathways to the total ATP turnover of proliferating MCF-7 breast cancer cells. | Q40734573 | ||
| The rate of cell growth is regulated by purine biosynthesis via ATP production and G(1) to S phase transition | Q40870453 | ||
| Intracellular ATP levels determine cell death fate by apoptosis or necrosis. | Q41110278 | ||
| Nucleotide pools in Novikoff rat hepatoma cells growing in suspension culture. 3. Effects of nucleosides in medium on levels of nucleotides in separate nucleotide pools for nuclear and cytoplasmic RNA synthesis | Q41152200 | ||
| The analysis of metabolite channelling in multienzyme complexes and multifunctional proteins | Q42010950 | ||
| c-Myc depletion inhibits proliferation of human tumor cells at various stages of the cell cycle | Q42115767 | ||
| Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo | Q42198162 | ||
| High information throughput analysis of nucleotides and their isotopically enriched isotopologues by direct-infusion FTICR-MS. | Q42410693 | ||
| Small inhibitory RNA duplexes for Sp1 mRNA block basal and estrogen-induced gene expression and cell cycle progression in MCF-7 breast cancer cells | Q42522132 | ||
| Glutaminolysis and insulin secretion: from bedside to bench and back | Q42528599 | ||
| Dynamic profiling of the glucose metabolic network in fasted rat hepatocytes using [1,2-13C2]glucose | Q42622750 | ||
| Overexpression of the Mitochondrial Folate and Glycine–Serine Pathway: A New Determinant of Methotrexate Selectivity in Tumors | Q42722444 | ||
| K-ras codon-specific mutations produce distinctive metabolic phenotypes in NIH3T3 mice [corrected] fibroblasts | Q42812919 | ||
| A hierarchy of ATP-consuming processes in mammalian cells | Q42822664 | ||
| 13C-pyruvate imaging reveals alterations in glycolysis that precede c-Myc-induced tumor formation and regression | Q42822782 | ||
| Gleevec (STI571) influences metabolic enzyme activities and glucose carbon flow toward nucleic acid and fatty acid synthesis in myeloid tumor cells. | Q43699000 | ||
| Advances in the Stable Isotope–Mass Spectrometric Measurement of DNA Synthesis and Cell Proliferation | Q43793875 | ||
| Measurements of ATP in mammalian cells | Q44021176 | ||
| Differential Control of Cell Cycle, Proliferation, and Survival of Primary T Lymphocytes by Purine and Pyrimidine Nucleotides | Q44432122 | ||
| Estrogen receptor/Sp1 complexes are required for induction of cad gene expression by 17beta-estradiol in breast cancer cells | Q44440498 | ||
| Intracellular ATP is required for mitochondrial apoptotic pathways in isolated hypoxic rat cardiac myocytes | Q44543591 | ||
| A c-Myc-MicroRNA functional feedback loop affects hepatocarcinogenesis | Q44714902 | ||
| Breakdown of the regulatory control of pyrimidine biosynthesis in human breast cancer cells | Q44781008 | ||
| Compartmentation of glycolysis and glycogenolysis in the perfused rat heart | Q44820827 | ||
| Quantitation of erythrocyte pentose pathway flux with [2-13C]glucose and 1H NMR analysis of the lactate methyl signal | Q44916241 | ||
| The anti-inflammatory action of methotrexate is not mediated by lymphocyte apoptosis, but by the suppression of activation and adhesion molecules | Q45216641 | ||
| Abnormalities in glucose uptake and metabolism in imatinib-resistant human BCR-ABL-positive cells. | Q46033036 | ||
| Mass isotopomer study of the nonoxidative pathways of the pentose cycle with [1,2-13C2]glucose. | Q46119052 | ||
| Elevated activity of the oxidative and non-oxidative pentose phosphate pathway in (pre)neoplastic lesions in rat liver. | Q46636561 | ||
| Revisiting the 13C-label distribution of the non-oxidative branch of the pentose phosphate pathway based upon kinetic and genetic evidence | Q46714527 | ||
| Metabolic profiling by 13C-NMR spectroscopy: [1,2-13C2]glucose reveals a heterogeneous metabolism in human leukemia T cells | Q46855250 | ||
| Cell cycle regulation of purine synthesis by phosphoribosyl pyrophosphate and inorganic phosphate | Q46867283 | ||
| Dual binding mode of a novel series of DHODH inhibitors. | Q46945934 | ||
| The separation of normal human leukocytes by density and classification by size | Q47393393 | ||
| 5 The determination of the partial specific volume of proteins by the mechanical oscillator technique | Q47906030 | ||
| The phosphorylation potential generated by respiring mitochondria | Q47997872 | ||
| Relationships between the rate of synthesis of ATP and the concentrations of reactants and products of ATP hydrolysis in maize root tips, determined by 31P nuclear magnetic resonance | Q49218604 | ||
| Regulation and mechanism of phosphoribosylpyrophosphate synthetase. V. Inhibition by end products and regulation by adenosine diphosphate. | Q50235337 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 4 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | carbohydrate | Q11358 |
| nucleotide | Q28745 | ||
| P304 | page(s) | 2466-2485 | |
| P577 | publication date | 2015-01-27 | |
| 2015-02-27 | |||
| P1433 | published in | Nucleic Acids Research | Q135122 |
| P1476 | title | Regulation of mammalian nucleotide metabolism and biosynthesis | |
| P478 | volume | 43 |
| Q40082053 | A Critical Role of Glutamine and Asparagine γ-Nitrogen in Nucleotide Biosynthesis in Cancer Cells Hijacked by an Oncogenic Virus |
| Q40175945 | A Novel Anti-Hepatitis C Virus and Antiproliferative Agent Alters Metabolic Networks in HepG2 and Hep3B Cells |
| Q58692000 | A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3 |
| Q92638386 | A conserved role of the insulin-like signaling pathway in diet-dependent uric acid pathologies in Drosophila melanogaster |
| Q36615429 | A liaison between mTOR signaling, ribosome biogenesis and cancer |
| Q55259322 | A novel thymidylate synthase from the Vibrionales, Alteromonadales, Aeromonadales, and Pasteurellales (VAAP) clade with altered nucleotide and folate binding sites. |
| Q88581128 | A review of HPRT and its emerging role in cancer |
| Q55401962 | Actionable Metabolic Pathways in Heart Failure and Cancer—Lessons From Cancer Cell Metabolism. |
| Q48045671 | Actions of p-synephrine on hepatic enzyme activities linked to carbohydrate metabolism and ATP levels in vivo and in the perfused rat liver |
| Q42283243 | Activation of the NRF2 antioxidant program generates an imbalance in central carbon metabolism in cancer |
| Q55265387 | Alternative assembly of respiratory complex II connects energy stress to metabolic checkpoints. |
| Q35908707 | An Essential Role of the Mitochondrial Electron Transport Chain in Cell Proliferation Is to Enable Aspartate Synthesis |
| Q60046306 | An efficient proteome-wide strategy for discovery and characterization of cellular nucleotide-protein interactions |
| Q36849513 | Applications of NMR spectroscopy to systems biochemistry |
| Q53693795 | Arbidol (Umifenovir): A Broad-Spectrum Antiviral Drug That Inhibits Medically Important Arthropod-Borne Flaviviruses. |
| Q48857636 | Arginine Deprivation Inhibits the Warburg Effect and Upregulates Glutamine Anaplerosis and Serine Biosynthesis in ASS1-Deficient Cancers. |
| Q90539666 | Basic Concepts of Genetics |
| Q60045712 | Bretschneider solution-induced alterations in the urine metabolome in cardiac surgery patients |
| Q90425876 | CD98hc (SLC3A2) sustains amino acid and nucleotide availability for cell cycle progression |
| Q64899590 | Cancer Cells Tune the Signaling Pathways to Empower de Novo Synthesis of Nucleotides. |
| Q36122257 | Cell cycle progression is an essential regulatory component of phospholipid metabolism and membrane homeostasis. |
| Q48552145 | Chloroformate derivatization for tracing the fate of Amino acids in cells and tissues by multiple stable isotope resolved metabolomics (mSIRM). |
| Q92025041 | Colorectal cancers utilize glutamine as an anaplerotic substrate of the TCA cycle in vivo |
| Q64104146 | Common patterns of gene regulation associated with Cesarean section and the development of islet autoimmunity - indications of immune cell activation |
| Q35329806 | Consequences of impaired purine recycling on the proteome in a cellular model of Lesch-Nyhan disease. |
| Q104569471 | Considerations for using isolated cell systems to understand cardiac metabolism and biology |
| Q47238975 | Control of Nucleotide Metabolism Enables Mutant p53's Oncogenic Gain-of-Function Activity |
| Q47999164 | Conversion of PRPS Hexamer to Monomer by AMPK-Mediated Phosphorylation Inhibits Nucleotide Synthesis in Response to Energy Stress |
| Q60909437 | Coordinative metabolism of glutamine carbon and nitrogen in proliferating cancer cells under hypoxia |
| Q36887749 | Cross Talk between Nucleotide Synthesis Pathways with Cellular Immunity in Constraining Hepatitis E Virus Replication |
| Q36254067 | Crude Extracts, Flavokawain B and Alpinetin Compounds from the Rhizome of Alpinia mutica Induce Cell Death via UCK2 Enzyme Inhibition and in Turn Reduce 18S rRNA Biosynthesis in HT-29 Cells |
| Q93058477 | Cryo-EM structures demonstrate human IMPDH2 filament assembly tunes allosteric regulation |
| Q49829014 | DNA Damage, Repair, and Cancer Metabolism. |
| Q98280997 | Decitabine- and 5-azacytidine resistance emerges from adaptive responses of the pyrimidine metabolism network |
| Q53688741 | Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease |
| Q92881406 | Dexamethasone-Induced Perturbations in Tissue Metabolomics Revealed by Chemical Isotope Labeling LC-MS analysis |
| Q92102948 | Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites |
| Q94565400 | Entry of glucose- and glutamine-derived carbons into the citric acid cycle supports early steps of HIV-1 infection in CD4 T cells |
| Q88390986 | Formate rescues neural tube defects caused by mutations in Slc25a32 |
| Q33834498 | From Krebs to clinic: glutamine metabolism to cancer therapy. |
| Q99549790 | From canonical to modified nucleotides: balancing translation and metabolism |
| Q58761959 | Fumarate hydratase loss promotes mitotic entry in the presence of DNA damage after ionising radiation |
| Q93257498 | Functional Analysis of the Role of Equilibrative Nucleobase Transporter 1 (ENBT1/SLC43A3) in Adenine Transport in HepG2 Cells |
| Q91673538 | Global alteration of T-lymphocyte metabolism by PD-L1 checkpoint involves a block of de novo nucleoside phosphate synthesis |
| Q48237710 | Glucose Limitation Alters Glutamine Metabolism in MUC1-Overexpressing Pancreatic Cancer Cells |
| Q41887078 | Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers |
| Q41056091 | Glutaminase inhibitor CB-839 synergizes with carfilzomib in resistant multiple myeloma cells |
| Q99564929 | Glutamine reliance in cell metabolism |
| Q90749493 | Hepatic Metabolic Derangements Triggered by Hyperthermia: An In Vitro Metabolomic Study |
| Q57174877 | Homology Modeling Informs Ligand Discovery for the Glutamine Transporter ASCT2 |
| Q39261665 | Hopefully devoted to Q: targeting glutamine addiction in cancer |
| Q58086605 | Identification of inhibitors of the dNTP triphosphohydrolase SAMHD1 using a novel and direct high throughput assay |
| Q64993423 | Identifying and targeting cancer-specific metabolism with network-based drug target prediction. |
| Q59800410 | Immune Response-Dependent Assembly of IMP Dehydrogenase Filaments |
| Q98237886 | Immunometabolism and HIV-1 pathogenesis: food for thought |
| Q92768544 | Immunometabolism: A new target for improving cancer immunotherapy |
| Q37694431 | Impact of Metabolism on T-Cell Differentiation and Function and Cross Talk with Tumor Microenvironment |
| Q92191147 | Impact of a High Protein Intake on the Plasma Metabolome in Elderly Males: 10 Week Randomized Dietary Intervention |
| Q28598169 | Importance of metabolic rate to the relationship between the number of genes in a functional category and body size in Peto's paradox for cancer |
| Q55025540 | In Silico Discovery of Potential Uridine-Cytidine Kinase 2 Inhibitors from the Rhizome of Alpinia mutica. |
| Q51733559 | Influence of Inflammation in the Process of T Lymphocyte Differentiation: Proliferative, Metabolic, and Oxidative Changes |
| Q55668835 | Integrated omics and gene expression analysis identifies the loss of metabolite–metabolite correlations in small cell lung cancer. |
| Q41273604 | Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes |
| Q26770381 | Interplay Between Metabolism and Oncogenic Process: Role of microRNAs |
| Q47288278 | Isotope labeling to determine the dynamics of metabolic response in CHO cell perfusion bioreactors using MALDI-TOF-MS. |
| Q89481519 | Laser-emission imaging of nuclear biomarkers for high-contrast cancer screening and immunodiagnosis |
| Q49269403 | Leveraging increased cytoplasmic nucleoside kinase activity to target mtDNA and oxidative phosphorylation in AML. |
| Q57124791 | Long Noncoding RNA Signature and Disease Outcome in Estrogen Receptor-Positive Breast Cancer Patients Treated with Tamoxifen |
| Q52357490 | Loss of KDM6A Activates Super-Enhancers to Induce Gender-Specific Squamous-like Pancreatic Cancer and Confers Sensitivity to BET Inhibitors. |
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