A Novel Anti-Hepatitis C Virus and Antiproliferative Agent Alters Metabolic Networks in HepG2 and Hep3B Cells

scientific article published on 2 June 2017

A Novel Anti-Hepatitis C Virus and Antiproliferative Agent Alters Metabolic Networks in HepG2 and Hep3B Cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/METABO7020023
P932PMC publication ID5487994
P698PubMed publication ID28574427

P50authorJeff IdleQ57972311
Diren BeyoğluQ73454803
P2093author name stringŞ Güniz Küçükgüzel
Adrian Keogh
Sevil Şenkardeş
P2860cites workMetabolic alterations and hepatitis C: From bench to bedsideQ26773261
Factors associated with the response to interferon-based antiviral therapies for chronic hepatitis CQ26825715
Sodium dependent multivitamin transporter (SMVT): a potential target for drug deliveryQ26863420
Glutathione synthetase deficiencyQ28259316
BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesisQ29617585
The epidemiological changes of HCV and HBV infections in the era of new antiviral therapies and the anti-HBV vaccineQ30252122
Biotin uptake by human intestinal and liver epithelial cells: role of the SMVT systemQ34184789
Distinctive pharmacological differences between liver cancer cell lines HepG2 and Hep3B.Q34962165
The current state of drug discovery and a potential role for NMR metabolomicsQ35072850
The metabolomic profile of gamma-irradiated human hepatoma and muscle cells reveals metabolic changes consistent with the Warburg effect.Q36514148
The glycine deportation system and its pharmacological consequences.Q36880287
Metabolomics as a Challenging Approach for Medicinal Chemistry and Personalized Medicine.Q53054318
The mechanism of pantothenate transport by rat liver parenchymal cells in primary cultureQ70083063
Cancer metabolism: a therapeutic perspectiveQ89947416
Tissue metabolomics of hepatocellular carcinoma: tumor energy metabolism and the role of transcriptomic classification.Q36961679
Apoptosis and glutathione: beyond an antioxidant.Q37574928
A quick look at biochemistry: carbohydrate metabolismQ38107290
Update on hepatitis C virus resistance to direct-acting antiviral agentsQ38218790
Regulation of mammalian nucleotide metabolism and biosynthesisQ38335072
The Crabtree and Warburg effects: Do metabolite-induced regulations participate in their induction?Q38804967
Current status and future prospects of chemotherapy for advanced hepatocellular carcinomaQ38843057
The plasma lipidome in acute myeloid leukemia at diagnosis in relation to clinical disease featuresQ38884878
Major involvement of Na(+) -dependent multivitamin transporter (SLC5A6/SMVT) in uptake of biotin and pantothenic acid by human brain capillary endothelial cells.Q38895031
Metabolic Hallmarks of Tumor and Immune Cells in the Tumor MicroenvironmentQ39197674
Antitumor effect of SIRT1 inhibition in human HCC tumor models in vitro and in vivo.Q39206845
Glutathione reductase plays an anti-apoptotic role against oxidative stress in human hepatoma cellsQ39725657
The chemistry, pharmacology and clinical pharmacology of diflunisalQ39773990
Interindividual variation in gene expression responses and metabolite formation in acetaminophen-exposed primary human hepatocytesQ40146321
Sorafenib (BAY 43-9006) inhibits tumor growth and vascularization and induces tumor apoptosis and hypoxia in RCC xenograft modelsQ40198053
Cell cycle-dependent regulation of pyrimidine biosynthesisQ40689222
Synthesis of novel diflunisal hydrazide-hydrazones as anti-hepatitis C virus agents and hepatocellular carcinoma inhibitors.Q40860497
Accumulation of human promyelocytic leukemic (HL-60) cells at two energetic cell cycle checkpointsQ40965797
Metabolomics reveals that aldose reductase activity due to AKR1B10 is upregulated in hepatitis C virus infection.Q41610203
Endogenous and xenobiotic metabolic stability of primary human hepatocytes in long-term 3D spheroid cultures revealed by a combination of targeted and untargeted metabolomicsQ41870452
Dog bites man or man bites dog? The enigma of the amino acid conjugationsQ42106652
Measurements of ATP in mammalian cellsQ44021176
Potential Therapeutic Targets in Energy Metabolism Pathways of Breast CancerQ46393725
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectHepatitis C virusQ708693
metabolic networkQ2263094
P577publication date2017-06-02
P1433published inMetabolitesQ27724046
P1476titleA Novel Anti-Hepatitis C Virus and Antiproliferative Agent Alters Metabolic Networks in HepG2 and Hep3B Cells
P478volume7

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cites work (P2860)
Q89510059Metabolomic and Lipidomic Biomarkers for Premalignant Liver Disease Diagnosis and Therapy
Q41921666Robust Regression Analysis of GCMS Data Reveals Differential Rewiring of Metabolic Networks in Hepatitis B and C Patients.

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