Metabolic pathways in the post-genome era.

scientific article

Metabolic pathways in the post-genome era. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0968-0004(03)00064-1
P698PubMed publication ID12765837

P50authorBernhard PalssonQ4894212
Jason A. PapinQ37369558
David A. FellQ42668859
P2093author name stringNathan D Price
Sharon J Wiback
P2860cites workExtreme pathway lengths and reaction participation in genome-scale metabolic networksQ24682088
A general definition of metabolic pathways useful for systematic organization and analysis of complex metabolic networksQ28145745
Metabolic network structure determines key aspects of functionality and regulationQ28214885
Detection of elementary flux modes in biochemical networks: a promising tool for pathway analysis and metabolic engineering.Q33543834
Metabolic pathway analysis: basic concepts and scientific applications in the post-genomic era.Q33651317
Extreme pathway analysis of human red blood cell metabolismQ34178460
Metabolic modeling of microbial strains in silico.Q34179356
Analysis of metabolic capabilities using singular value decomposition of extreme pathway matricesQ34180306
Pathway alignment: application to the comparative analysis of glycolytic enzymesQ34505049
Metabolic modelling of microbes: the flux-balance approachQ34631271
Global properties of the metabolic map of Escherichia coliQ35027310
Metabolic control analysis: a survey of its theoretical and experimental developmentQ35860764
Stoichiometric network analysisQ38188547
Pathway databases: a case study in computational symbolic theoriesQ38523514
Genome-scale metabolic model of Helicobacter pylori 26695.Q39679903
Mathematical analysis of multienzyme systems. I. Modelling of the glycolysis of human erythrocytesQ39946555
Theory for the systemic definition of metabolic pathways and their use in interpreting metabolic function from a pathway-oriented perspectiveQ41724911
Assessment of the metabolic capabilities of Haemophilus influenzae Rd through a genome-scale pathway analysisQ41724916
Calculability analysis in underdetermined metabolic networks illustrated by a model of the central metabolism in purple nonsulfur bacteriaQ42163019
Model of 2,3-bisphosphoglycerate metabolism in the human erythrocyte based on detailed enzyme kinetic equations: computer simulation and metabolic control analysisQ42994531
Extreme pathways and Kirchhoff's second law.Q43122158
Exploring the pathway structure of metabolism: decomposition into subnetworks and application to Mycoplasma pneumoniaeQ43887992
Stoichiometric model for evaluating the metabolic capabilities of the facultative methylotroph Methylobacterium extorquens AM1, with application to reconstruction of C(3) and C(4) metabolismQ43937903
Analysis of carbon metabolism in Escherichia coli strains with an inactive phosphotransferase system by (13)C labeling and NMR spectroscopyQ43992565
The genome-scale metabolic extreme pathway structure in Haemophilus influenzae shows significant network redundancy.Q44019204
Metabolic pathway analysis of a recombinant yeast for rational strain developmentQ44062430
Constraints-based models: regulation of gene expression reduces the steady-state solution spaceQ45211444
Dynamic simulation of the human red blood cell metabolic networkQ46231124
The challenges of in silico biologyQ46255466
An Algebraic-combinatorial Model for the Identification and Mapping of Biochemical PathwaysQ52050893
METATOOL: for studying metabolic networks.Q52216547
Computer-aided synthesis of biochemical pathwaysQ52465888
Metabolic dynamics in the human red cell. Part I--A comprehensive kinetic modelQ52510891
Metabolic control theory: a structural approachQ52548981
MPS: An artificially intelligent software system for the analysis and synthesis of metabolic pathwaysQ52566720
Pathway analysis, engineering, and physiological considerations for redirecting central metabolism.Q54579293
ON ELEMENTARY FLUX MODES IN BIOCHEMICAL REACTION SYSTEMS AT STEADY STATEQ57320469
A functional genomics approach using metabolomics andin silicopathway analysisQ59834052
Integrated pathway–genome databases and their role in drug discoveryQ60309513
Complex biology with no parametersQ73954677
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectmetabolic pathwayQ68685
P1104number of pages9
P304page(s)250-258
P577publication date2003-05-01
P13046publication type of scholarly workreview articleQ7318358
P1433published inTrends in Biochemical SciencesQ1565711
P1476titleMetabolic pathways in the post-genome era.
P478volume28

Reverse relations

cites work (P2860)
Q35215331A depth-first search algorithm to compute elementary flux modes by linear programming
Q28754894A framework for evolutionary systems biology
Q44578300A novel metabolic cycle catalyzes glucose oxidation and anaplerosis in hungry Escherichia coli.
Q31090599A principal components method constrained by elementary flux modes: analysis of flux data sets.
Q33304395A procedure for the estimation over time of metabolic fluxes in scenarios where measurements are uncertain and/or insufficient
Q81157263Ab initio prediction of thermodynamically feasible reaction directions from biochemical network stoichiometry
Q30777076Advances in network-based metabolic pathway analysis and gene expression data integration.
Q51897409Algebraic method for the analysis of signaling crosstalk.
Q34921401Algorithmic and analytical methods in network biology
Q38017425Are we ready for genome-scale modeling in plants?
Q36982025Bacterial genome sequencing and its use in infectious diseases
Q39776363Bayesian flux balance analysis applied to a skeletal muscle metabolic model.
Q28472546Biosynthetic potentials of metabolites and their hierarchical organization
Q38300561Characterizing phenotype with tracer based metabolomics
Q38320332Clinical detection and characterization of bacterial pathogens in the genomics era.
Q33548126Comparative genomics of metabolic networks of free-living and parasitic eukaryotes
Q47593538Comparison of different approaches for identifying subnetworks in metabolic networks
Q33840569Comparison on extreme pathways reveals nature of different biological processes
Q24803776Computation of elementary modes: a unifying framework and the new binary approach
Q47374303Computational approaches to protein-protein interaction
Q34640884Computing minimal nutrient sets from metabolic networks via linear constraint solving
Q94101421Current Awareness on Comparative and Functional Genomics
Q37471556Database resources in metabolomics: an overview
Q44983542Deriving metabolic engineering strategies from genome-scale modeling with flux ratio constraints
Q54995027Development of network-based pathway definitions: the need to analyze real metabolic networks
Q42430397Dynamic metabolic flux analysis demonstrated on cultures where the limiting substrate is changed from carbon to nitrogen and vice versa
Q35667308Elementary Flux Mode Analysis Revealed Cyclization Pathway as a Powerful Way for NADPH Regeneration of Central Carbon Metabolism
Q37328003Elementary mode analysis: a useful metabolic pathway analysis tool for characterizing cellular metabolism
Q33299957Environmental variability and modularity of bacterial metabolic networks
Q33300475Estimation of the number of extreme pathways for metabolic networks
Q29614449Evidence for dynamically organized modularity in the yeast protein-protein interaction network
Q33350707Exhaustive identification of steady state cycles in large stoichiometric networks
Q43786003Expa: a program for calculating extreme pathways in biochemical reaction networks
Q46697439Expanding metabolic networks: scopes of compounds, robustness, and evolution
Q24793117Extending knowledge of Escherichia coli metabolism by modeling and experiment
Q34646772Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it.
Q42801045Flexibility in energy metabolism supports hypoxia tolerance in Drosophila flight muscle: metabolomic and computational systems analysis
Q36748701Functional genomics in chickens: development of integrated-systems microarrays for transcriptional profiling and discovery of regulatory pathways
Q36945352Functional genomics of the chicken--a model organism.
Q37902554Functional proteomics: application of mass spectrometry to the study of enzymology in complex mixtures
Q28475555Functional states of the genome-scale Escherichia coli transcriptional regulatory system
Q42939175Generation and Evaluation of a Genome-Scale Metabolic Network Model of Synechococcus elongatus PCC7942.
Q39968205Genome-scale in silico models of E. coli have multiple equivalent phenotypic states: assessment of correlated reaction subsets that comprise network states.
Q34268420Genome-scale modeling using flux ratio constraints to enable metabolic engineering of clostridial metabolism in silico
Q33391538Genome-scale models of bacterial metabolism: reconstruction and applications
Q29616789Genome-scale models of microbial cells: evaluating the consequences of constraints
Q28473829Genome-scale reconstruction and analysis of the Pseudomonas putida KT2440 metabolic network facilitates applications in biotechnology
Q48621890Hexokinase and not glycogen synthase controls the flux through the glycogen synthesis pathway in frog oocytes
Q51141733In silico metabolic engineering of Clostridium ljungdahlii for synthesis gas fermentation
Q49270277Insights into metabolic osmoadaptation of the ectoines-producer bacterium Chromohalobacter salexigens through a high-quality genome scale metabolic model.
Q24795542Integrated analysis of metabolic phenotypes in Saccharomyces cerevisiae
Q33940698Integrative Analysis of Many Weighted Co-Expression Networks Using Tensor Computation
Q37993825Kinetic modelling of plant metabolic pathways
Q47310995Linking metabolic network features to phenotypes using sparse group lasso.
Q33879405Lipid body formation plays a central role in cell fate determination during developmental differentiation of Myxococcus xanthus
Q34157632Loss of dispensable genes is not adaptive in yeast
Q33806474MEMOSys: Bioinformatics platform for genome-scale metabolic models
Q28469032Matrix formalism to describe functional states of transcriptional regulatory systems
Q41789680MetaPath Online: a web server implementation of the network expansion algorithm
Q33849784Metabolic Network-Based Interpretation of Gene Expression Data Elucidates Human Cellular Metabolism
Q34188024Metabolic control analysis under uncertainty: framework development and case studies
Q38992090Metabolic modeling of synthesis gas fermentation in bubble column reactors
Q35778015Metabolic modeling predicts metabolite changes in Mycobacterium tuberculosis
Q47363112Metabolic network analysis of the causes and evolution of enzyme dispensability in yeast
Q37033446Metabolic network model of a human oral pathogen.
Q38032459Metabolome 2.0: quantitative genetics and network biology of metabolic phenotypes
Q37286414Metabolomics Analysis of the Larval Head of the Silkworm, Bombyx mori
Q34986572Minimal metabolic pathway structure is consistent with associated biomolecular interactions
Q55020721Mining of potential drug targets through the identification of essential and analogous enzymes in the genomes of pathogens of Glycine max, Zea mays and Solanum lycopersicum.
Q24791425Model-independent fluxome profiling from 2H and 13C experiments for metabolic variant discrimination
Q36343560Modelling strategies for the industrial exploitation of lactic acid bacteria
Q26849400Multi -omics and metabolic modelling pipelines: challenges and tools for systems microbiology
Q34632986Neisseria meningitidis: biology, microbiology, and epidemiology.
Q28212164Network-based analysis of metabolic regulation in the human red blood cell
Q37038558Network-based approaches for linking metabolism with environment
Q33236264Network-level analysis of metabolic regulation in the human red blood cell using random sampling and singular value decomposition
Q38606272Observing metabolic functions at the genome scale
Q55098387On an algorithmic definition for the components of the minimal cell.
Q51023424On dynamically generating relevant elementary flux modes in a metabolic network using optimization
Q36539130On the way to understand biological complexity in plants: S-nutrition as a case study for systems biology
Q51637852Pathway knockout and redundancy in metabolic networks
Q28471830Pathway projector: web-based zoomable pathway browser using KEGG atlas and Google Maps API
Q34576205Physicochemical modelling of cell signalling pathways.
Q34231664Prediction of dynamic behavior of mutant strains from limited wild-type data
Q37436174Prediction of substrate-enzyme-product interaction based on molecular descriptors and physicochemical properties
Q34389154Predictive Potential of Flux Balance Analysis of Saccharomyces cerevisiae Using as Optimization Function Combinations of Cell Compartmental Objectives
Q37884605Prospects for the Future Using Genomics and Proteomics in Clinical Microbiology
Q83485774Quantification of metabolism in Saccharomyces cerevisiae under hyperosmotic conditions using elementary mode analysis
Q28552402Quantitative Determination of Flexible Pharmacological Mechanisms Based On Topological Variation in Mice Anti-Ischemic Modular Networks
Q33238510Quantitative elementary mode analysis of metabolic pathways: the example of yeast glycolysis
Q33285703RMBNToolbox: random models for biochemical networks
Q33361469Rapidly exploring structural and dynamic properties of signaling networks using PathwayOracle
Q34385115Reconstruction of cellular signalling networks and analysis of their properties
Q38335072Regulation of mammalian nucleotide metabolism and biosynthesis
Q33277970Regulation of metabolic networks by small molecule metabolites
Q28769658Regulatory on/off minimization of metabolic flux changes after genetic perturbations
Q56987273Response to comment on 'Can sugars be produced from fatty acids? A test case for pathway analysis tools'
Q55053302SolCyc: a database hub at the Sol Genomics Network (SGN) for the manual curation of metabolic networks in Solanum and Nicotiana specific databases.
Q36639674Spatiotemporal modeling of microbial metabolism
Q41983355Specific and Nonhomologous Isofunctional Enzymes of the Genetic Information Processing Pathways as Potential Therapeutical Targets for Tritryps
Q24629149Stable isotope-resolved metabolomics and applications for drug development
Q24807041Structural comparison of metabolic networks in selected single cell organisms
Q61803767Systems Biology Approaches Toward Understanding Primary Mitochondrial Diseases
Q26824124Systems biology approaches for discovering biomarkers for traumatic brain injury
Q38008573Systems biology tools for toxicology
Q40288125The JAK-STAT signaling network in the human B-cell: an extreme signaling pathway analysis
Q51602866The evolution of molecular biology into systems biology
Q34352367The geometry of the flux cone of a metabolic network
Q33941094The role of nonlinearity in computing graph-theoretical properties of resting-state functional magnetic resonance imaging brain networks
Q28472336The signaling petri net-based simulator: a non-parametric strategy for characterizing the dynamics of cell-specific signaling networks
Q34281789The soluble and membrane-bound transhydrogenases UdhA and PntAB have divergent functions in NADPH metabolism of Escherichia coli
Q35905293The systems biology of glycosylation
Q37780305Tracer-based metabolomics: concepts and practices
Q34187246Uniform sampling of steady-state flux spaces: means to design experiments and to interpret enzymopathies.
Q58571231Unlocking conserved and diverged metabolic characteristics in cassava carbon assimilation via comparative genomics approach
Q48655743Using logic programming for modeling the one-carbon metabolism network to study the impact of folate deficiency on methylation processes
Q30426796Whole-genome metabolic network reconstruction and constraint-based modeling
Q34189294k-Cone analysis: determining all candidate values for kinetic parameters on a network scale
Q37855850¹H NMR-based metabonomics for investigating diabetes

Search more.