Antimalarial drug discovery - the path towards eradication.

scientific article published on 17 July 2013

Antimalarial drug discovery - the path towards eradication. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1017/S0031182013000826
P932PMC publication ID3884835
P698PubMed publication ID23863111

P50authorJeremy BurrowsQ87131067
Timothy N C WellsQ55182082
P2093author name stringPaul Willis
David Waterson
Didier Leroy
Thomas Spangenberg
Brice Campo
Emilie Burlot
Sarah Jeanneret
Stephanie Cherbuin
P2860cites workEvidence of Artemisinin-Resistant Malaria in Western CambodiaQ22061854
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Spirotetrahydro beta-carbolines (spiroindolones): a new class of potent and orally efficacious compounds for the treatment of malaria.Q39616001
Plasmodium berghei parasite transformed with green fluorescent protein for screening blood schizontocidal agentsQ41914401
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Optimal dose finding for novel antimalarial combination therapyQ42210267
The biology of sexual development of Plasmodium: the design and implementation of transmission-blocking strategiesQ42562371
Targeting the parasite in the mosquito: rationale and practicality.Q47165551
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Global phenotypic screening for antimalarialsQ26824875
Designing the next generation of medicines for malaria control and eradicationQ26859195
Structure-Guided Lead Optimization of Triazolopyrimidine-Ring Substituents Identifies Potent Plasmodium falciparum Dihydroorotate Dehydrogenase Inhibitors with Clinical Candidate PotentialQ27670499
Malarial dihydrofolate reductase as a paradigm for drug development against a resistance-compromised targetQ27674154
Imaging of Plasmodium Liver Stages to Drive Next-Generation Antimalarial Drug DiscoveryQ27861956
A murine model of falciparum-malaria by in vivo selection of competent strains in non-myelodepleted mice engrafted with human erythrocytesQ28472751
A research agenda for malaria eradication: drugsQ28476806
Towards an in vitro model of Plasmodium hypnozoites suitable for drug discoveryQ28477602
The activities of current antimalarial drugs on the life cycle stages of Plasmodium: a comparative study with human and rodent parasitesQ28480979
P. falciparum in vitro killing rates allow to discriminate between different antimalarial mode-of-actionQ28481199
The open access malaria box: a drug discovery catalyst for neglected diseasesQ28533977
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A Research Agenda to Underpin Malaria EradicationQ33818020
Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugsQ33898575
Can primaquine therapy for vivax malaria be improved?Q33965030
Development and optimization of a novel 384-well anti-malarial imaging assay validated for high-throughput screeningQ34122581
Imidazolopiperazines: lead optimization of the second-generation antimalarial agentsQ34270117
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malariaQ34693880
Costs and cost-effectiveness of malaria control interventions--a systematic reviewQ35589032
Cyclopropyl carboxamides, a chemically novel class of antimalarial agents identified in a phenotypic screenQ35598598
Multiple antibiotics exert delayed effects against the Plasmodium falciparum apicoplastQ36095096
The global pipeline of new medicines for the control and elimination of malariaQ36320249
A framework for assessing the risk of resistance for anti-malarials in developmentQ36340996
First-in-man safety and pharmacokinetics of synthetic ozonide OZ439 demonstrates an improved exposure profile relative to other peroxide antimalarialsQ36573154
In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screenQ36736936
Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancyQ37076814
Identification of a metabolically stable triazolopyrimidine-based dihydroorotate dehydrogenase inhibitor with antimalarial activity in miceQ37352712
Malaria, sexual development and transmission: retrospect and prospectQ37574197
Targeting the hypnozoite reservoir of Plasmodium vivax: the hidden obstacle to malaria eliminationQ37687630
The state of the art in anti-malarial drug discovery and developmentQ37852739
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectmalariaQ12156
eukaryoteQ19088
Plasmodium falciparumQ311383
antimalarialQ521616
drug discoveryQ1418791
biomedical investigative techniqueQ66648976
organism formQ55597235
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P304page(s)128-139
P577publication date2013-07-17
2014-01-01
P1433published inParasitologyQ15753259
P1476titleAntimalarial drug discovery - the path towards eradication
P478volume141

Reverse relations

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