Clonal expansions and short telomeres are associated with neoplasia in early-onset, but not late-onset, ulcerative colitis

scientific article

Clonal expansions and short telomeres are associated with neoplasia in early-onset, but not late-onset, ulcerative colitis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1097/MIB.0B013E3182A87640
P8608Fatcat IDrelease_qnvqapebvfapdht3awzv4tl6fy
P932PMC publication ID3885330
P698PubMed publication ID24097228

P50authorMarshall HorwitzQ55690391
Peter S. RabinovitchQ67522938
P2093author name stringMary P Bronner
Teresa A Brentnall
Lawrence A Loeb
Aasthaa Bansal
David A Crispin
Lisa A Lai
Cigdem H Ussakli
Jesse J Salk
Rosa Ana Risques
P2860cites workNatural history of elderly-onset inflammatory bowel disease: a population-based cohort studyQ86114218
Telomere measurement by quantitative PCRQ24529938
The risk of colorectal cancer in ulcerative colitis: a meta-analysisQ24669747
Oxidative stress shortens telomeresQ29615533
A genetic explanation of Slaughter's concept of field cancerization: evidence and clinical implicationsQ33965561
Patients with late-adult-onset ulcerative colitis have better outcomes than those with early onset diseaseQ34037161
Detection of ultra-rare mutations by next-generation sequencingQ34291814
Mutations in the p53 gene: an early marker of neoplastic progression in ulcerative colitis.Q34330775
Passenger mutations as a marker of clonal cell lineages in emerging neoplasiaQ34361056
Sex disparities in colorectal cancer incidence by anatomic subsite, race and ageQ34542974
Cellular senescence in cancer and agingQ34581486
Ulcerative colitis-associated colorectal cancer arises in a field of short telomeres, senescence, and inflammation.Q34802663
Age at diagnosis of inflammatory bowel disease influences early development of colorectal cancer in inflammatory bowel disease patients: a nationwide, long-term surveyQ36468969
Recent trends in the prevalence of Crohn's disease and ulcerative colitis in a commercially insured US population.Q36622034
Single molecule molecular inversion probes for targeted, high-accuracy detection of low-frequency variationQ36800445
Diagnosis and management of dysplasia in patients with ulcerative colitis and Crohn's disease of the colonQ37305789
Clonal expansions in ulcerative colitis identify patients with neoplasiaQ37426977
The incidence and prevalence of inflammatory bowel disease among U.S. veterans: a national cohort studyQ37678171
Pre-tumour clones, periodic selection and clonal interference in the origin and progression of gastrointestinal cancer: potential for biomarker development.Q38071593
Genome instability and agingQ38080561
Decreasing risk of colorectal cancer in patients with inflammatory bowel disease over 30 yearsQ38433080
Sequence dependent instability of mononucleotide microsatellites in cultured mismatch repair proficient and deficient mammalian cellsQ38454872
Pancolonic chromosomal instability precedes dysplasia and cancer in ulcerative colitisQ41698505
Chromosomal instability in ulcerative colitis is related to telomere shorteningQ44159326
Declining risk of colorectal cancer in inflammatory bowel disease: an updated meta-analysis of population-based cohort studiesQ44347539
Neoplastic progression in ulcerative colitis: histology, DNA content, and loss of a p53 allele.Q52860008
Telomere length in the colon declines with age: a relation to colorectal cancer?Q54613758
Adjusting for covariates in studies of diagnostic, screening, or prognostic markers: an old concept in a new settingQ81269798
Molecular underpinnings of cancer in ulcerative colitisQ81379430
Two distinct groups of colorectal cancer in inflammatory bowel diseaseQ81622844
P433issue12
P304page(s)2593-2602
P577publication date2013-11-01
P1433published inInflammatory Bowel DiseasesQ15749161
P1476titleClonal expansions and short telomeres are associated with neoplasia in early-onset, but not late-onset, ulcerative colitis
P478volume19

Reverse relations

cites work (P2860)
Q28076165Biomarkers for colitis-associated colorectal cancer
Q93043617Cancer-Associated Mutations but No Cancer: Insights into the Early Steps of Carcinogenesis and Implications for Early Cancer Detection
Q38973304Clonal evolution of colorectal cancer in IBD.
Q58553780From Colitis to Cancer: An Evolutionary Trajectory That Merges Maths and Biology
Q93183882Mitochondrial DNA Mutations are Associated with Ulcerative Colitis Preneoplasia but Tend to be Negatively Selected in Cancer
Q53181025Precancer in ulcerative colitis: the role of the field effect and its clinical implications.
Q33748463Reduced hTERT protein levels are associated with DNA aneuploidy in the colonic mucosa of patients suffering from longstanding ulcerative colitis
Q99581395Role of telomere shortening in anticipation of inflammatory bowel disease
Q58796418Sequence analysis of integrated hepatitis B virus DNA during HBeAg-seroconversion
Q34599076TP53/p53 alterations and Aurora A expression in progressor and non-progressor colectomies from patients with longstanding ulcerative colitis
Q37485252Telomere shortening correlates to dysplasia but not to DNA aneuploidy in longstanding ulcerative colitis