Diverse drug-resistant subpopulations of Mycobacterium tuberculosis are sustained in continuous culture

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Diverse drug-resistant subpopulations of Mycobacterium tuberculosis are sustained in continuous culture is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1098/RSIF.2016.0745
P932PMC publication ID5134024
P698PubMed publication ID27807274

P50authorCaroline ColijnQ41044022
P2093author name stringJoanna Bacon
Diepreye Ayabina
Charlotte Hendon-Dunn
P2860cites workEvolution of drug resistance in Mycobacterium tuberculosis: clinical and molecular perspectiveQ24535810
Probability distribution of drug-resistant mutants in unselected populations of Mycobacterium tuberculosisQ24624866
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Resistance levels and rpoB gene mutations among in vitro-selected rifampin-resistant Mycobacterium tuberculosis mutantsQ42550095
Exogenous reinfection as a cause of multidrug-resistant and extensively drug-resistant tuberculosis in rural South AfricaQ42599882
Single-nucleotide polymorphism-based differentiation and drug resistance detection in Mycobacterium tuberculosis from isolates or directly from sputumQ45243572
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Isoniazid’s Bactericidal Activity Ceases because of the Emergence of Resistance, Not Depletion ofMycobacterium tuberculosisin the Log Phase of GrowthQ58033536
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Molecular genetic basis of antimicrobial agent resistance in Mycobacterium tuberculosis: 1998 updateQ28143206
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Evaluation of a nutrient starvation model of Mycobacterium tuberculosis persistence by gene and protein expression profilingQ28487482
Mycobacterium tuberculosis Is Resistant to Isoniazid at a Slow Growth Rate by Single Nucleotide Polymorphisms in katG Codon Ser315Q28548282
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Levels of bacterial community diversity in four arid soils compared by cultivation and 16S rRNA gene cloning.Q30658782
Molecular analysis of bacterial community structure and diversity in unimproved and improved upland grass pasturesQ30658788
The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeastQ33392677
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Unique flexibility in energy metabolism allows mycobacteria to combat starvation and hypoxiaQ33523042
Exploring the collaboration between antibiotics and the immune response in the treatment of acute, self-limiting infectionsQ33767602
Characterization of spontaneous, In vitro-selected, rifampin-resistant mutants of Mycobacterium tuberculosis strain H37RvQ33980958
Increase in bacterial community diversity in subsurface aquifers receiving livestock wastewater input.Q33986730
Biphasic kill curve of isoniazid reveals the presence of drug-tolerant, not drug-resistant, Mycobacterium tuberculosis in the guinea pig.Q34018978
Macromolecular Composition During Steady-State Growth of Escherichia coli B/rQ34052488
Detection of mutations associated with isoniazid resistance in Mycobacterium tuberculosis isolates from ChinaQ34143763
Population genetics study of isoniazid resistance mutations and evolution of multidrug-resistant Mycobacterium tuberculosis.Q34973711
Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihoodQ34985618
Use of whole genome sequencing to estimate the mutation rate of Mycobacterium tuberculosis during latent infectionQ35006626
The role of clonal interference in the evolutionary dynamics of plasmid-host adaptationQ36099779
The multiplicity of divergence mechanisms in a single evolving populationQ36245287
Mixed-strain mycobacterium tuberculosis infections and the implications for tuberculosis treatment and controlQ36361918
Chemostats and epidemics: competition for nutrients/hostsQ38163574
The influence of reduced oxygen availability on pathogenicity and gene expression in Mycobacterium tuberculosisQ38449680
Persisters, persistent infections and the Yin-Yang modelQ38514259
Stationary phase gene expression of Mycobacterium tuberculosis following a progressive nutrient depletion: a model for persistent organisms?Q38730565
Single nucleotide polymorphisms in genes associated with isoniazid resistance in Mycobacterium tuberculosisQ39743333
The competitive cost of antibiotic resistance in Mycobacterium tuberculosisQ40311130
Effect of rpoB mutations conferring rifampin resistance on fitness of Mycobacterium tuberculosisQ40572948
P433issue124
P921main subjectMycobacterium tuberculosisQ130971
P577publication date2016-11-01
P1433published inJournal of the Royal Society InterfaceQ2492390
P1476titleDiverse drug-resistant subpopulations of Mycobacterium tuberculosis are sustained in continuous culture
P478volume13

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cites work (P2860)
Q47112934A Novel TetR-Like Transcriptional Regulator Is Induced in Acid-Nitrosative Stress and Controls Expression of an Efflux Pump in Mycobacteria
Q90131019Re-growth of Mycobacterium tuberculosis populations exposed to antibiotic combinations is due to the presence of isoniazid and not bacterial growth rate

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