| scholarly article | Q13442814 |
| P50 | author | Nikos K. Karamanos | Q42321957 |
| P2093 | author name string | Achilleas D Theocharis | |
| Spyros S Skandalis | |||
| Angeliki Korpetinou | |||
| Argyrios Noulas | |||
| Vassiliki T Labropoulou | |||
| Gianna Smirlaki | |||
| P2860 | cites work | Towards a proteome-scale map of the human protein–protein interaction network | Q21735930 |
| Synthesis, secretion, and subcellular localization of serglycin proteoglycan in human endothelial cells | Q24290730 | ||
| Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation | Q24292521 | ||
| Serglycin constitutively secreted by myeloma plasma cells is a potent inhibitor of bone mineralization in vitro | Q24298121 | ||
| Ubiquitin-independent Proteasomal Degradation of Endoplasmic Reticulum-localized Connexin43 Mediated by CIP75 | Q24302500 | ||
| DDA3 recruits microtubule depolymerase Kif2a to spindle poles and controls spindle dynamics and mitotic chromosome movement | Q24321493 | ||
| Ubiquilin4 is an adaptor protein that recruits Ubiquilin1 to the autophagy machinery | Q24322965 | ||
| A directed protein interaction network for investigating intracellular signal transduction | Q24337382 | ||
| A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration | Q24337490 | ||
| In vitro reconstitution of complexes between pro-matrix metalloproteinase-9 and the proteoglycans serglycin and versican | Q24338750 | ||
| A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes | Q24647928 | ||
| Serglycin: a structural and functional chameleon with wide impact on immune cells | Q27004626 | ||
| Serglycin in health and diseases | Q27021780 | ||
| Apoptosis induced by granzyme B-glycosaminoglycan complexes: implications for granule-mediated apoptosis in vivo | Q28142990 | ||
| The human serglycin gene. Nucleotide sequence and methylation pattern in human promyelocytic leukemia HL-60 cells and T-lymphoblast Molt-4 cells | Q28187490 | ||
| Characterization of the human gene that encodes the peptide core of secretory granule proteoglycans in promyelocytic leukemia HL-60 cells and analysis of the translated product | Q28244722 | ||
| Widespread expression of chondroitin sulfate-type serglycins with CD44 binding ability in hematopoietic cells | Q28251584 | ||
| Serglycin--structure and biology | Q28260380 | ||
| Localization of human platelet proteoglycan gene to chromosome 10, band q22.1, by in situ hybridization | Q28275329 | ||
| Serglycin-binding proteins in activated macrophages and platelets | Q28276873 | ||
| Isolation and characterization of a cDNA that encodes the peptide core of the secretory granule proteoglycan of human promyelocytic leukemia HL-60 cells | Q28280919 | ||
| Serglycin and betaglycan proteoglycans are expressed in the megakaryocytic cell line CHRF 288-11 and normal human megakaryocytes | Q28289582 | ||
| Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting | Q28298681 | ||
| Serglycin is essential for maturation of mast cell secretory granule | Q28504754 | ||
| Delayed contraction of the CD8+ T cell response toward lymphocytic choriomeningitis virus infection in mice lacking serglycin | Q28507393 | ||
| Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage | Q28508375 | ||
| Serglycin Is a Major Proteoglycan in Polarized Human Endothelial Cells and Is Implicated in the Secretion of the Chemokine GROα/CXCL1 | Q42576979 | ||
| Serglycin is a novel adipocytokine highly expressed in epicardial adipose tissue | Q42826020 | ||
| Serglycin proteoglycan is required for secretory granule integrity in mucosal mast cells | Q42912814 | ||
| Promoter regulatory elements and DNase I-hypersensitive sites involved in serglycin proteoglycan gene expression in human erythroleukemia, CHRF 288-11, and HL-60 cells | Q43595440 | ||
| Sulfated proteoglycans and sulfated proteins in guinea pig megakaryocytes and platelets in vivo. Relevance to megakaryocyte maturation and platelet activation | Q44213460 | ||
| Acidic glycosaminoglycans in human platelets and leukocytes: the isolation and enzymatic characterization of chondroitin 4-sulfate | Q44252467 | ||
| Serotonin and histamine storage in mast cell secretory granules is dependent on serglycin proteoglycan | Q46782717 | ||
| Secretion of proteases in serglycin transfected Madin-Darby canine kidney cells. | Q46899559 | ||
| Expression of the serglycin gene in human leukemic cell lines | Q52229454 | ||
| Regulation of rat mast cell protease 1 activity. Protease inhibition is prevented by heparin proteoglycan. | Q54161550 | ||
| Intestinal mucosal mast cells from rats infected with Nippostrongylus brasiliensis contain protease-resistant chondroitin sulfate di-B proteoglycans. | Q54426116 | ||
| Native heparin from rat peritoneal mast cells | Q67541685 | ||
| Oversulfated chondroitin sulfate proteoglycan in cultured human peritoneal macrophages | Q69636451 | ||
| Modulation of the expression of chondroitin sulfate proteoglycan in stimulated human monocytes | Q69699984 | ||
| Human gastric mucosal mast cells are chondroitin sulphate E-containing mast cells | Q70359595 | ||
| Effect of a proteoglycan produced by rat tumor cells on their adhesion to fibronectin-collagen substrata | Q71233209 | ||
| Isolation and characterization of glycosaminoglycans from human leukocytes and platelets | Q72307052 | ||
| Serglycin proteoglycan synthesis in the murine uterine decidua and early embryo | Q73919336 | ||
| Regulation of the activity of secreted human lung mast cell tryptase by mast cell proteoglycans | Q77631624 | ||
| Interleukin-1beta selectively decreases the synthesis of versican by arterial smooth muscle cells | Q79568298 | ||
| Neutrophil elastase depends on serglycin proteoglycan for localization in granules | Q79710976 | ||
| Neutrophil elastase is associated with serglycin on its way to lysosomes in U937 cells | Q80581544 | ||
| Serglycin proteoglycan in hematologic malignancies: a marker of acute myeloid leukemia | Q81422106 | ||
| Molecular interactions of MMP-13 C-terminal domain with chondrocyte proteins | Q82513965 | ||
| Platelets alter tumor cell attributes to propel metastasis: programming in transit | Q82557107 | ||
| Mast cells express tyrosine hydroxylase and store dopamine in a serglycin-dependent manner | Q84214412 | ||
| Serglycin (SRGN) overexpression predicts poor prognosis in hepatocellular carcinoma patients | Q87344337 | ||
| A novel heparin-dependent processing pathway for human tryptase. Autocatalysis followed by activation with dipeptidyl peptidase I. | Q37352048 | ||
| Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44(hi/)CD24 (lo/-) stem cell phenotype in human breast cancer | Q37762478 | ||
| Serglycin proteoglycan deletion in mouse platelets: physiological effects and their implications for platelet contributions to thrombosis, inflammation, atherosclerosis, and metastasis | Q37784312 | ||
| Proteoglycans in health and disease: novel roles for proteoglycans in malignancy and their pharmacological targeting. | Q37788815 | ||
| Cancer and the Complement Cascade | Q37792654 | ||
| CD44: can a cancer-initiating cell profit from an abundantly expressed molecule? | Q37851351 | ||
| Pathophysiology and pharmacological targeting of tumor-induced bone disease: current status and emerging therapeutic interventions. | Q37856334 | ||
| ETS family of genes in leukemia and Down syndrome. | Q37866110 | ||
| Glycosaminoglycans: key players in cancer cell biology and treatment | Q37983930 | ||
| Proteoglycans in haemopoietic cells | Q38012046 | ||
| Adhesion receptors as therapeutic targets for circulating tumor cells | Q38030018 | ||
| CEP proteins: the knights of centrosome dynasty | Q38086108 | ||
| Immune infiltrates as predictive markers of survival in pancreatic cancer patients | Q38129379 | ||
| Heparin proteoglycans synthesized by mouse mastocytoma contain chondroitin sulphate | Q38290965 | ||
| Interaction of heparin with rat mast cell protease 1. | Q38308072 | ||
| Mechanism by which heparin proteoglycan modulates mast cell chymase activity | Q38319936 | ||
| DNase I hypersensitivity patterns of the serglycin proteoglycan gene in resting and phorbol 12-myristate 13-acetate-stimulated human erythroleukemia (HEL), CHRF 288-11, and HL-60 cells compared with neutrophils and human umbilical vein endothelial c | Q38350110 | ||
| Transcriptional regulation of a hematopoietic proteoglycan core protein gene during hematopoiesis. | Q38507913 | ||
| Expression pattern of a hematopoietic proteoglycan core protein gene during human hematopoiesis | Q38508990 | ||
| Involvement of Bag6 and the TRC pathway in proteasome assembly | Q38864831 | ||
| Cell-surface serglycin promotes adhesion of myeloma cells to collagen type I and affects the expression of matrix metalloproteinases. | Q39198639 | ||
| Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis | Q39441340 | ||
| Serglycin is a theranostic target in nasopharyngeal carcinoma that promotes metastasis | Q39598855 | ||
| Serglycin inhibits the classical and lectin pathways of complement via its glycosaminoglycan chains: implications for multiple myeloma | Q39602521 | ||
| Calcium‐induced activation and truncation of promatrix metalloproteinase‐9 linked to the core protein of chondroitin sulfate proteoglycans | Q40631335 | ||
| Macrophages secrete matrix metalloproteinase 9 covalently linked to the core protein of chondroitin sulphate proteoglycans | Q40839467 | ||
| Suppressive subtractive hybridisation reveals differential expression of serglycin, sorcin, bone marrow proteoglycan and prostate-tumour-inducing gene I (PTI-1) in drug-resistant and sensitive tumour cell lines of haematopoetic origin | Q40900180 | ||
| Serglycin secreted by leukocytes is efficiently eliminated from the circulation by sinusoidal scavenger endothelial cells in the liver | Q40900677 | ||
| Stimulation of serglycin and CD44 mRNA expression in endothelial cells exposed to TNF-alpha and IL-1alpha | Q40937567 | ||
| Sulfated glycosaminoglycans of guinea pig basophilic leukocytes | Q41041928 | ||
| Proteoglycan synthesis in human erythroleukaemia (HEL) cells | Q41887611 | ||
| Isolation and characterization of sulphated mucopolysaccharides from rat leukaemic (RBL-1) basophils | Q41948014 | ||
| Proteoglycan-19, laminin and collagen type IV production is correlated with the levels of mRNA in F9 cell aggregates differentiating in the presence or absence of cyclic AMP. | Q41996101 | ||
| Changes in glycosaminoglycan biosynthesis during differentiation in vitro of human monocytes | Q42052845 | ||
| Primary structure of a mouse mastocytoma proteoglycan core protein | Q42163032 | ||
| Glycosaminoglycans in rat mucosal mast cells | Q42166107 | ||
| Serglycin proteoglycan promotes apoptotic versus necrotic cell death in mast cells | Q42182871 | ||
| Serglycin is the major secreted proteoglycan in macrophages and has a role in the regulation of macrophage tumor necrosis factor-alpha secretion in response to lipopolysaccharide | Q28513593 | ||
| Decreased serglycin proteoglycan size is associated with the platelet alpha granule storage defect in Wistar Furth hereditary macrothrombocytopenic rats. Serglycin binding affinity to type I collagen is unaltered | Q28564717 | ||
| Serglycin proteoglycan is sorted into zymogen granules of rat pancreatic acinar cells | Q28570385 | ||
| Structural requirements and mechanism for heparin-induced activation of a recombinant mouse mast cell tryptase, mouse mast cell protease-6: formation of active tryptase monomers in the presence of low molecular weight heparin | Q28590282 | ||
| A novel ligand for CD44 is serglycin, a hematopoietic cell lineage-specific proteoglycan. Possible involvement in lymphoid cell adherence and activation | Q28591757 | ||
| SGTA antagonizes BAG6-mediated protein triage | Q28596609 | ||
| Breast cancer cells induce stromal fibroblasts to secrete ADAMTS1 for cancer invasion through an epigenetic change | Q28730586 | ||
| Serglycin proteoglycan expression and synthesis in embryonic stem cells. | Q30332493 | ||
| Cytotoxic cell granule-mediated apoptosis. Characterization of the macromolecular complex of granzyme B with serglycin | Q30864967 | ||
| Chymase bound to heparin is resistant to its natural inhibitors and capable of proteolyzing high density lipoproteins in aortic intimal fluid | Q32063001 | ||
| A key role for mast cell chymase in the activation of pro-matrix metalloprotease-9 and pro-matrix metalloprotease-2. | Q33210291 | ||
| Glycosaminoglycan (GAG) Biosynthesis and GAG-Binding Proteins | Q33391706 | ||
| Identification of chondroitin sulfate E proteoglycans and heparin proteoglycans in the secretory granules of human lung mast cells | Q33564244 | ||
| A human functional protein interaction network and its application to cancer data analysis | Q33581341 | ||
| Proteomic identification of CD44 interacting proteins | Q33758420 | ||
| Ultraviolet irradiation induces the accumulation of chondroitin sulfate, but not other glycosaminoglycans, in human skin | Q33988271 | ||
| Activation of human interstitial procollagenase through direct cleavage of the Leu83-Thr84 bond by mast cell chymase. | Q34329991 | ||
| Serglycin-independent release of active mast cell proteases in response to Toxoplasma gondii infection | Q34352022 | ||
| A role for serglycin proteoglycan in mast cell apoptosis induced by a secretory granule-mediated pathway. | Q34568468 | ||
| Serglycin is implicated in the promotion of aggressive phenotype of breast cancer cells | Q35036132 | ||
| Chondroitin sulfates play a major role in breast cancer metastasis: a role for CSPG4 and CHST11 gene expression in forming surface P-selectin ligands in aggressive breast cancer cells | Q35558089 | ||
| Mast Cell Proteases and Inflammation | Q35572708 | ||
| Intracellular proteoglycans | Q35647324 | ||
| Identification of specific chondroitin sulfate species in cutaneous autoimmune disease | Q35681780 | ||
| Alu elements: know the SINEs | Q35907659 | ||
| The role of inflammatory cells in fostering pancreatic cancer cell growth and invasion | Q36202213 | ||
| Molecular cloning and sequence analysis of a chondroitin sulfate proteoglycan cDNA. | Q36490716 | ||
| Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice | Q36508868 | ||
| Structural remodeling of proteoglycans upon retinoic acid-induced differentiation of NCCIT cells | Q36565975 | ||
| UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy | Q36673081 | ||
| Chondroitin sulfate as a key molecule in the development of atherosclerosis and cancer progression | Q36713856 | ||
| Proteoglycans in cancer biology, tumour microenvironment and angiogenesis | Q36787608 | ||
| Protease-proteoglycan complexes of mouse and human mast cells and importance of their beta-tryptase-heparin complexes in inflammation and innate immunity | Q36819900 | ||
| The N-end rule proteolytic system in autophagy | Q37043032 | ||
| P921 | main subject | inflammation | Q101991 |
| P304 | page(s) | 327 | |
| P577 | publication date | 2014-01-13 | |
| P1433 | published in | Frontiers in Oncology | Q26839986 |
| P1476 | title | Serglycin: at the crossroad of inflammation and malignancy | |
| P478 | volume | 3 |
| Q37282934 | Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer. |
| Q59812942 | Dual Transcriptomics of Host-Pathogen Interaction of Cystic Fibrosis Isolate PASS1 With Zebrafish |
| Q28573682 | Elevated urinary urea by high-protein diet could be one of the inducements of bladder disorders |
| Q39411671 | Epigenetic Regulation of the Biosynthesis & Enzymatic Modification of Heparan Sulfate Proteoglycans: Implications for Tumorigenesis and Cancer Biomarkers |
| Q50106742 | Expression of serglycin in human disc is increased in degenerated discs and up-regulated in vitro by exposure to IL-1ß or TNF-α. |
| Q55436772 | Heparan sulfate proteoglycans undergo differential expression alterations in left sided colorectal cancer, depending on their metastatic character. |
| Q35813723 | Heparan sulfate proteoglycans undergo differential expression alterations in right sided colorectal cancer, depending on their metastatic character |
| Q37725457 | Identification of novel follicular dendritic cell sarcoma markers, FDCSP and SRGN, by whole transcriptome sequencing. |
| Q40060038 | Impaired response of the bronchial epithelium to inflammation characterizes severe equine asthma |
| Q42178728 | Increased Expression of Serglycin in Specific Carcinomas and Aggressive Cancer Cell Lines |
| Q28085548 | Insights into the key roles of proteoglycans in breast cancer biology and translational medicine |
| Q27329598 | Melanoma cell lysosome secretory burst neutralizes the CTL-mediated cytotoxicity at the lytic synapse |
| Q64966094 | Mitogen-Activated Protein Kinase Signaling Regulates Proteoglycan Composition of Mast Cell Secretory Granules. |
| Q54949772 | Multi-lectin Affinity Chromatography and Quantitative Proteomic Analysis Reveal Differential Glycoform Levels between Prostate Cancer and Benign Prostatic Hyperplasia Sera. |
| Q47281580 | Over forty years of bladder cancer glycobiology: Where do glycans stand facing precision oncology? |
| Q38822694 | Proteoglycan expression correlates with the phenotype of malignant and non-malignant EBV-positive B-cell lines. |
| Q21710680 | Proteoglycan form and function: A comprehensive nomenclature of proteoglycans |
| Q26772304 | Proteoglycans in liver cancer |
| Q38616484 | Proteoglycans: Potential Agents in Mammographic Density and the Associated Breast Cancer Risk |
| Q48010288 | Role of the extracellular matrix in cancer-associated epithelial to mesenchymal transition phenomenon |
| Q38690536 | Serglycin as a potential biomarker for glioma: association of serglycin expression, extent of mast cell recruitment and glioblastoma progression |
| Q38882752 | Shed proteoglycans in tumor stroma. |
| Q28552442 | Targeting Serglycin Prevents Metastasis in Murine Mammary Carcinoma |
| Q36036383 | The effect of acute and long-term physical activity on extracellular matrix and serglycin in human skeletal muscle |
| Q94547218 | The role of SRGN in the survival and immune infiltrates of skin cutaneous melanoma (SKCM) and SKCM-metastasis patients |
| Q38806104 | The role of heparins and nano-heparins as therapeutic tool in breast cancer |
| Q90397345 | The role of increased synovial fluid A disintegrin and metalloproteinase with thrombospondin motifs4 and serglycin levels in osteoarthritis |
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