Chondroitin sulfate as a key molecule in the development of atherosclerosis and cancer progression

scientific article published on January 2006

Chondroitin sulfate as a key molecule in the development of atherosclerosis and cancer progression is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/S1054-3589(05)53013-8
P698PubMed publication ID17239771

P2093author name stringNikos K Karamanos
A D Theocharis
G N Tzanakakis
I Tsolakis
P2860cites workVersican interacts with chemokines and modulates cellular responsesQ28138079
Characterization of heparin affin regulatory peptide signaling in human endothelial cellsQ28242363
Midkine and pleiotrophin in neural development and cancerQ28249687
Proteoglycans in atherosclerosis and restenosis: key roles for versicanQ28261672
Matrix proteoglycans: from molecular design to cellular functionQ28284300
Negative regulation of transforming growth factor-beta by the proteoglycan decorinQ28292224
High-performance capillary electrophoretic analysis of hyaluronan and galactosaminoglycan-disaccharides in gastrointestinal carcinomas. Differential disaccharide composition as a possible tool-indicator for malignanciesQ31039421
Human abdominal aortic aneurysm is characterized by decreased versican concentration and specific downregulation of versican isoform V(0).Q31886397
Impaired elastin fiber assembly related to reduced 67-kD elastin-binding protein in fetal lamb ductus arteriosus and in cultured aortic smooth muscle cells treated with chondroitin sulfateQ34216561
Recent advances in the structural biology of chondroitin sulfate and dermatan sulfateQ34271235
Retrovirally mediated overexpression of versican v3 reverses impaired elastogenesis and heightened proliferation exhibited by fibroblasts from Costello syndrome and Hurler disease patientsQ34286189
Proteoglycans and tumor progression: Janus-faced molecules with contradictory functions in cancer.Q34706643
Versican: a versatile extracellular matrix proteoglycan in cell biologyQ34858300
Extracellular matrix in vascular morphogenesis and disease: structure versus signalQ35024836
The role of proteoglycans in cell adhesion, migration and proliferationQ35455376
Involvement of stromal proteoglycans in tumour progressionQ35703715
Proteoglycans: structures and interactionsQ37285263
Identification of the principal proteoglycan-binding site in LDL. A single-point mutation in apo-B100 severely affects proteoglycan interaction without affecting LDL receptor bindingQ37383221
Oversulfated chondroitin/dermatan sulfates containing GlcAbeta1/IdoAalpha1-3GalNAc(4,6-O-disulfate) interact with L- and P-selectin and chemokinesQ38292486
Identification of the proteoglycan binding site in apolipoprotein B48.Q40724243
Binding of a large chondroitin sulfate/dermatan sulfate proteoglycan, versican, to L-selectin, P-selectin, and CD44.Q40860247
Identification and characterization of ligands for L-selectin in the kidney. I. Versican, a large chondroitin sulfate proteoglycan, is a ligand for L-selectinQ40957934
Specificity of the low density lipoprotein-glycosaminoglycan interactionQ43603450
Overexpression of the V3 variant of versican alters arterial smooth muscle cell adhesion, migration, and proliferation in vitro.Q43864458
Human coronary smooth muscle cells internalize versican-modified LDL through LDL receptor-related protein and LDL receptorsQ43909337
Specific molecular interactions of oversulfated chondroitin sulfate E with various heparin-binding growth factors. Implications as a physiological binding partner in the brain and other tissuesQ44131360
Decreased biglycan expression and differential decorin localization in human abdominal aortic aneurysmsQ44205488
Altered content composition and structure of glycosaminoglycans and proteoglycans in gastric carcinomaQ44280557
Matrix proteoglycans are markedly affected in advanced laryngeal squamous cell carcinomaQ47345541
The Proteoglycan Decorin Links Low Density Lipoproteins with Collagen Type IQ62023755
Glycosaminoglycan fractions from human arteries presenting diverse susceptibilities to atherosclerosis have different binding affinities to plasma LDLQ72689994
Human abdominal aortic aneurysm is closely associated with compositional and specific structural modifications at the glycosaminoglycan levelQ72996241
Chondroitin 4-sulphate exhibits inhibitory effect during Cu2+-mediated LDL oxidationQ73094739
Pancreatic carcinoma is characterized by elevated content of hyaluronan and chondroitin sulfate with altered disaccharide compositionQ73098910
Decorin inhibits cell migration through a process requiring its glycosaminoglycan side chainQ73119221
Association of apo B lipoproteins with arterial proteoglycans: pathological significance and molecular basisQ77124466
Retrovirally mediated overexpression of versican v3 by arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointima after vascular injuryQ77743543
CD44, a cell surface chondroitin sulfate proteoglycan, mediates binding of interferon-gamma and some of its biological effects on human vascular smooth muscle cellsQ77926846
Human colon adenocarcinoma is associated with specific post-translational modifications of versican and decorinQ78390022
Compositional and structural alterations of chondroitin and dermatan sulfates during the progression of atherosclerosis and aneurysmal dilatation of the human abdominal aortaQ78578854
P407language of work or nameEnglishQ1860
P921main subjectatherosclerosisQ12252367
P304page(s)281-295
P577publication date2006-01-01
P1433published inAdvances in PharmacologyQ15753809
P1476titleChondroitin sulfate as a key molecule in the development of atherosclerosis and cancer progression
P478volume53

Reverse relations

cites work (P2860)
Q28828562"On-The-Spot" Arresting of Chondroitin Sulphate Proteoglycans: Implications for Ovarian Adenocarcinoma Recognition and Intervention
Q40007453Association between Human Plasma Chondroitin Sulfate Isomers and Carotid Atherosclerotic Plaques
Q54096113Biomolecular analysis of matrix proteoglycans as biomarkers in non small cell lung cancer.
Q35131282Biphasic role of chondroitin sulfate in cardiac differentiation of embryonic stem cells through inhibition of Wnt/β-catenin signaling
Q38725258Burkitt lymphoma expresses oncofetal chondroitin sulfate without being a reservoir for placental malaria sequestration
Q37282934Cell-matrix interactions: focus on proteoglycan-proteinase interplay and pharmacological targeting in cancer.
Q36960622Chondroitin Sulfate in Solution: Effects of Mono- and Divalent Salts
Q39950503Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway.
Q38260546Chondroitinase: A promising therapeutic enzyme
Q35894756Dermatan sulfate is involved in the tumorigenic properties of esophagus squamous cell carcinoma
Q36736328Effect of chondroitin sulphate in a rabbit model of atherosclerosis aggravated by chronic arthritis
Q90706035Four targeted genes for predicting the prognosis of colorectal cancer: A bioinformatics analysis case
Q64249445Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation
Q37983930Glycosaminoglycans: key players in cancer cell biology and treatment
Q36730629Inhibition of versican expression by siRNA facilitates tropoelastin synthesis and elastic fiber formation by human SK-LMS-1 leiomyosarcoma smooth muscle cells in vitro and in vivo
Q33724421Monitoring serum chondroitin sulfate levels in patients submitted to coronary artery bypass surgery.
Q37470684Oncofetal Chondroitin Sulfate Glycosaminoglycans Are Key Players in Integrin Signaling and Tumor Cell Motility.
Q34456785Primary ovarian carcinomas and abdominal metastasis contain 4,6-disulfated chondroitin sulfate rich regions, which provide adhesive properties to tumour cells
Q35036132Serglycin is implicated in the promotion of aggressive phenotype of breast cancer cells
Q37467048Serglycin: at the crossroad of inflammation and malignancy
Q39875693Structure and regulation of the versican promoter: the versican promoter is regulated by AP-1 and TCF transcription factors in invasive human melanoma cells
Q64951034Targeted siRNA Nanoparticles for Mammary Carcinoma Therapy.
Q36212978Targeting arterial wall sulfated glycosaminoglycans in rabbit atherosclerosis with a mouse/human chimeric antibody.
Q37784307The Roles of Chondroitin-4-Sulfotransferase-1 in Development and Disease
Q36853007Upregulation of decorin by FXR in vascular smooth muscle cells

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