| scholarly article | Q13442814 |
| P50 | author | Sara S Parker | Q60814120 |
| Theodore J. Price | Q38327722 | ||
| Janko Nikolich-Žugich | Q42651893 | ||
| P2093 | author name string | Sourav Ghosh | |
| Heddwen L Brooks | |||
| Emily L Goldberg | |||
| Nader Sanai | |||
| Yael Kusne | |||
| Kirsten H Limesand | |||
| Irina Y Maskaykina | |||
| Sophie M Hapak | |||
| Wade M Chew | |||
| P2860 | cites work | Neural consequences of environmental enrichment | Q22337282 |
| Exercise enhances learning and hippocampal neurogenesis in aged mice. | Q24537320 | ||
| Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice | Q24597354 | ||
| Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity | Q24598427 | ||
| The glial nature of embryonic and adult neural stem cells | Q24602498 | ||
| mTOR is a key modulator of ageing and age-related disease | Q24610741 | ||
| The AMPK signalling pathway coordinates cell growth, autophagy and metabolism | Q24616273 | ||
| mTOR signaling in growth control and disease | Q24634174 | ||
| Rapamycin fed late in life extends lifespan in genetically heterogeneous mice | Q24647805 | ||
| mTOR regulates memory CD8 T-cell differentiation | Q24648624 | ||
| A complex interplay between Akt, TSC2 and the two mTOR complexes | Q24655791 | ||
| Brain IGF-1 receptors control mammalian growth and lifespan through a neuroendocrine mechanism | Q27332330 | ||
| Rapamycins: mechanism of action and cellular resistance | Q28189252 | ||
| The utility of Ki-67 and BrdU as proliferative markers of adult neurogenesis | Q28207636 | ||
| Transient expression of doublecortin during adult neurogenesis | Q28212071 | ||
| Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation | Q28276337 | ||
| Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB | Q28306356 | ||
| Metformin in obesity, cancer and aging: addressing controversies | Q28480735 | ||
| DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212 | Q28513802 | ||
| The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin | Q28590162 | ||
| Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants | Q29547516 | ||
| New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? | Q29619386 | ||
| Chronic antidepressant treatment increases neurogenesis in adult rat hippocampus | Q29619400 | ||
| Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice | Q30569745 | ||
| Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube | Q43224792 | ||
| Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition | Q43643471 | ||
| Neurosphere and neurosphere-forming cells: morphological and ultrastructural characterization | Q44671985 | ||
| Astrocyte-specific overexpression of insulin-like growth factor-I promotes brain overgrowth and glial fibrillary acidic protein expression | Q45093081 | ||
| The pharmacology of mTOR inhibition | Q46041824 | ||
| Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin | Q46488462 | ||
| Regulation of C. elegans longevity by specific gustatory and olfactory neurons | Q46621417 | ||
| Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells. | Q46767739 | ||
| Type 1 insulin-like growth factor receptor signaling is essential for the development of the hippocampal formation and dentate gyrus | Q47814285 | ||
| Astrocyte-like cells as a main target for estrogen action during neuronal differentiation | Q48272809 | ||
| Mammalian target of rapamycin signaling is a key regulator of the transit-amplifying progenitor pool in the adult and aging forebrain. | Q48319912 | ||
| Integration of new neurons into functional neural networks. | Q48361346 | ||
| Metformin supplementation and life span in Fischer-344 rats | Q33790444 | ||
| The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. | Q33928657 | ||
| Metformin activates an atypical PKC-CBP pathway to promote neurogenesis and enhance spatial memory formation | Q34032680 | ||
| The cerebrospinal fluid provides a proliferative niche for neural progenitor cells | Q34169014 | ||
| Rapamycin slows aging in mice | Q34275079 | ||
| When neurogenesis encounters aging and disease | Q34311443 | ||
| mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK. | Q34340709 | ||
| BrdU immunohistochemistry for studying adult neurogenesis: paradigms, pitfalls, limitations, and validation | Q34571476 | ||
| Fluoxetine targets early progenitor cells in the adult brain | Q34611258 | ||
| Modification of hippocampal circuitry by adult neurogenesis | Q34636021 | ||
| If started early in life, metformin treatment increases life span and postpones tumors in female SHR mice. | Q34852281 | ||
| Lifespan extension induced by AMPK and calcineurin is mediated by CRTC-1 and CREB | Q34995412 | ||
| Adult hippocampal neurogenesis buffers stress responses and depressive behaviour | Q35182020 | ||
| Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling | Q35370616 | ||
| CB2 cannabinoid receptors promote neural progenitor cell proliferation via mTORC1 signaling | Q35668816 | ||
| Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain | Q35772025 | ||
| Tuberous sclerosis and insulin resistance. Unlikely bedfellows reveal a TORrid affair | Q35990247 | ||
| Gap 1 phase length and mouse embryonic stem cell self-renewal | Q36140649 | ||
| Mammalian target of rapamycin complex 1 (mTORC1) and 2 (mTORC2) control the dendritic arbor morphology of hippocampal neurons | Q36216334 | ||
| Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice | Q36268050 | ||
| Calorie restriction mimetics: an emerging research field | Q36454381 | ||
| Eat less, live longer? New insights into the role of caloric restriction in the brain | Q36980574 | ||
| TrkB regulates hippocampal neurogenesis and governs sensitivity to antidepressive treatment | Q37127162 | ||
| Development of neural circuits in the adult hippocampus | Q37475604 | ||
| Targeting adenosine monophosphate-activated protein kinase (AMPK) in preclinical models reveals a potential mechanism for the treatment of neuropathic pain | Q38624930 | ||
| Regulation of neurogenesis and epidermal growth factor receptor signaling by the insulin receptor/target of rapamycin pathway in Drosophila | Q39217640 | ||
| Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells | Q39743196 | ||
| Grb10 and active Raf-1 kinase promote Bad-dependent cell survival | Q40126556 | ||
| Essential role of tuberous sclerosis genes TSC1 and TSC2 in NF-kappaB activation and cell survival. | Q40234467 | ||
| The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans | Q41711470 | ||
| Chronic hypoxia impairs murine hippocampal development and depletes the postnatal progenitor pool by attenuating mammalian target of rapamycin signaling | Q41973704 | ||
| Cdk4/cyclinD1 overexpression in neural stem cells shortens G1, delays neurogenesis, and promotes the generation and expansion of basal progenitors. | Q42459454 | ||
| DHEA prevents Aβ25-35-impaired survival of newborn neurons in the dentate gyrus through a modulation of PI3K-Akt-mTOR signaling | Q43157571 | ||
| P4510 | describes a project that uses | ImageJ | Q1659584 |
| P433 | issue | 1 | |
| P921 | main subject | metformin | Q19484 |
| sirolimus | Q32089 | ||
| P304 | page(s) | 199-212 | |
| P577 | publication date | 2013-08-16 | |
| P1433 | published in | Age | Q4691832 |
| P1476 | title | Contrasting effects of chronic, systemic treatment with mTOR inhibitors rapamycin and metformin on adult neural progenitors in mice | |
| P478 | volume | 36 |
| Q33993570 | Immune memory-boosting dose of rapamycin impairs macrophage vesicle acidification and curtails glycolysis in effector CD8 cells, impairing defense against acute infections |
| Q39607128 | Inhibition of mTOR by Rapamycin Results in Auditory Hair Cell Damage and Decreased Spiral Ganglion Neuron Outgrowth and Neurite Formation In Vitro |
| Q35080522 | Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms |
| Q64105328 | Metformin induces the AP-1 transcription factor network in normal dermal fibroblasts |
| Q34957274 | Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current |
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