Notch-1 signalling is activated in brain arteriovenous malformations in humans

scientific article published on December 2009

Notch-1 signalling is activated in brain arteriovenous malformations in humans is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1093/BRAIN/AWP246
P932PMC publication ID2792368
P698PubMed publication ID19812212
P5875ResearchGate publication ID237935374

P50authorMichael T LawtonQ71013029
Kunlin JinQ107353791
P2093author name stringLin Xie
Ming Zhong
Yongmei Chen
Guo-Yuan Yang
William L Young
David A Greenberg
XiaoOu Mao
Qichuan ZhuGe
Gourong Chen
WeiMing Zheng
P2860cites workMutations in the human Jagged1 gene are responsible for Alagille syndromeQ24314702
Notch signaling: cell fate control and signal integration in developmentQ27861061
The Notch-Hes pathway in mammalian neural developmentQ28145844
Notch signaling: control of cell communication and cell fateQ28245948
Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementiaQ28294011
Mouse hesr1 and hesr2 genes are redundantly required to mediate Notch signaling in the developing cardiovascular systemQ28304868
Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutantsQ28505269
Vascular patterning defects associated with expression of activated Notch4 in embryonic endotheliumQ28506571
Overexpression of delta-like 4 induces arterialization and attenuates vessel formation in developing mouse embryosQ28506962
The Notch target genes Hey1 and Hey2 are required for embryonic vascular developmentQ28586854
HRT1, HRT2, and HRT3: a new subclass of bHLH transcription factors marking specific cardiac, somitic, and pharyngeal arch segmentsQ28587806
Embryonic lethality and vascular defects in mice lacking the Notch ligand Jagged1Q28589104
Notch signaling is essential for vascular morphogenesis in miceQ29620377
Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in miceQ30483008
Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult miceQ33896087
Notch signaling is required for arterial-venous differentiation during embryonic vascular development.Q34093638
Notch signaling in vascular development and physiologyQ34646081
Racial/Ethnic differences in longitudinal risk of intracranial hemorrhage in brain arteriovenous malformation patientsQ34659159
Brain arteriovenous malformations in adultsQ36104974
Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development.Q37594746
Evidence of increased endothelial cell turnover in brain arteriovenous malformationsQ38460731
Involvement of RBP-J in biological functions of mouse Notch1 and its derivatives.Q41078359
Directed migration of neuronal precursors into the ischemic cerebral cortex and striatumQ42835101
A secreted Delta1-Fc fusion protein functions both as an activator and inhibitor of Notch1 signalingQ43972008
Growth and regression of arteriovenous malformations in a patient with hereditary hemorrhagic telangiectasiaQ59152590
Notch-mediated restoration of regenerative potential to aged muscleQ79331504
A garden of Notch-ly delightsQ80111418
P433issuePt 12
P407language of work or nameEnglishQ1860
P921main subjectarteriovenous malformationQ1584110
P304page(s)3231-3241
P577publication date2009-12-01
P1433published inBrainQ897386
P1476titleNotch-1 signalling is activated in brain arteriovenous malformations in humans
P478volume132

Reverse relations

cites work (P2860)
Q35008897A genome-wide investigation of copy number variation in patients with sporadic brain arteriovenous malformation
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Q38662338Arteriovenous malformations in hereditary haemorrhagic telangiectasia: looking beyond ALK1-NOTCH interactions.
Q41878326BMP9 induces EphrinB2 expression in endothelial cells through an Alk1-BMPRII/ActRII-ID1/ID3-dependent pathway: implications for hereditary hemorrhagic telangiectasia type II.
Q57813960Beyond endothelial cells: Vascular endothelial growth factors in heart, vascular anomalies and placenta
Q30301287Biology of cerebral arteriovenous malformations with a focus on inflammation
Q37897171Brain arteriovenous malformation pathogenesis: a response-to-injury paradigm
Q53396776Chronic Hippocampal Expression of Notch Intracellular Domain Induces Vascular Thickening, Reduces Glucose Availability, and Exacerbates Spatial Memory Deficits in a Rat Model of Early Alzheimer.
Q34752162Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels.
Q27302123Context-specific interactions between Notch and ALK1 cannot explain ALK1-associated arteriovenous malformations
Q30592602Deletion of Rbpj from postnatal endothelium leads to abnormal arteriovenous shunting in mice.
Q35538051Delta-like 4 mRNA is regulated by adjacent natural antisense transcripts
Q47156458Downregulation of the Long Non-Coding RNA Meg3 Promotes Angiogenesis After Ischemic Brain Injury by Activating Notch Signaling
Q37671796Endothelial signaling and the molecular basis of arteriovenous malformation
Q93030769Enhanced notch signaling modulates unproductive revascularization in response to nitric oxide-angiopoietin signaling in a mouse model of peripheral ischemia
Q96618200Evidence for endothelial-to-mesenchymal transition in human brain arteriovenous malformations
Q35169079Expression of the active Notch1 decreases MTC tumor growth in vivo.
Q36529825G Protein-Coupled Receptor 124 (GPR124) Gene Polymorphisms and Risk of Brain Arteriovenous Malformation
Q55183218Gene expression analysis of nidus of cerebral arteriovenous malformations reveals vascular structures with deficient differentiation and maturation.
Q35620061Gene expression profiling of blood in brain arteriovenous malformation patients
Q34824758Human brain arteriovenous malformations express lymphatic-associated genes
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Q35995125Notch receptor expression in human brain arteriovenous malformations
Q60300657Notch signaling pathway is a potential therapeutic target for extracranial vascular malformations
Q37561474Notch1 and 4 signaling responds to an increasing vascular wall shear stress in a rat model of arteriovenous malformations.
Q37425058Notch4 is activated in endothelial and smooth muscle cells in human brain arteriovenous malformations
Q41761841Notch4 normalization reduces blood vessel size in arteriovenous malformations
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Q34081311The ARUBA trial: current status, future hopes
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Q36304260Vascular Integrity in the Pathogenesis of Brain Arteriovenous Malformation

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