Innate immunity and toll-like receptor antagonists: a potential role in the treatment of cardiovascular diseases

scientific article published on January 2009

Innate immunity and toll-like receptor antagonists: a potential role in the treatment of cardiovascular diseases is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

External links are
P356DOI10.1111/J.1755-5922.2009.00077.X
P932PMC publication ID2832843
P698PubMed publication ID19426249
P5875ResearchGate publication ID24411952

P50authorJane E. FreedmanQ125127316
P2093author name stringLea M Beaulieu
Elaine Lin
P2860cites workAssociation between Toll-like receptors and the extent and severity of coronary artery disease in patients with stable anginaQ79436666
Inhibition of Toll-like receptor 4 with eritoran attenuates myocardial ischemia-reperfusion injuryQ79839081
Toll-like receptors 2-deficient mice are protected against postischemic coronary endothelial dysfunctionQ79856753
In vivo effects of lipopolysaccharide and TLR4 on platelet production and activity: implications for thrombotic riskQ80134207
Bacterial DNA induces myocardial inflammation and reduces cardiomyocyte contractility: role of toll-like receptor 9Q80492358
Synergistic proinflammatory effects of the antiviral cytokine interferon-alpha and Toll-like receptor 4 ligands in the atherosclerotic plaqueQ81444765
Expression of functional Toll-like receptors 2 and 4 in human aortic valve interstitial cells: potential roles in aortic valve inflammation and stenosisQ81453900
Evidence of Toll-like receptor molecules on human plateletsQ81479217
Association between plasma levels and immunolocalization of cytokines in heart valve lesions: a possible target for treatment?Q81947126
Immunology. Targeting the tollsQ83154044
The danger model: a renewed sense of selfQ28214633
Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytesQ28280597
Vascular cells contribute to atherosclerosis by cytokine- and innate-immunity-related inflammatory mechanismsQ30319434
Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic eventsQ33318184
Platelets express functional Toll-like receptor-4.Q33366814
Toll4 (TLR4) expression in cardiac myocytes in normal and failing myocardiumQ33853586
Critical role of extracellular heat shock cognate protein 70 in the myocardial inflammatory response and cardiac dysfunction after global ischemia-reperfusion.Q35109063
Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids.Q36459911
Emerging paradigm: toll-like receptor 4-sentinel for the detection of tissue damage.Q36626556
Mechanisms of disease: Toll-like receptors in cardiovascular diseaseQ36891895
Local expression of Toll-like receptor 4 at the site of ruptured plaques in patients with acute myocardial infarctionQ36907993
Angiotensin II AT1 receptor blockade decreases lipopolysaccharide-induced inflammation in the rat adrenal glandQ36972703
Engagement of specific innate immune signaling pathways during Porphyromonas gingivalis induced chronic inflammation and atherosclerosisQ36992344
Synthetic tetra-acylated derivatives of lipid A from Porphyromonas gingivalis are antagonists of human TLR4.Q37476115
Expression of Toll-like receptors on human plateletsQ37866864
Risk of myocardial infarction and stroke after acute infection or vaccinationQ39471364
Toll-like receptor stimulation in cardiomyoctes decreases contractility and initiates an NF-kappaB dependent inflammatory responseQ40217414
Soluble forms of Toll-like receptor (TLR)2 capable of modulating TLR2 signaling are present in human plasma and breast milkQ40609296
Candesartan inhibits Toll-like receptor expression and activity both in vitro and in vivoQ41969861
Stimulation of Toll-like receptor 2 in human platelets induces a thromboinflammatory response through activation of phosphoinositide 3-kinaseQ42137745
Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL.Q42514406
Lipopolysaccharide stimulation of human aortic valve interstitial cells activates inflammation and osteogenesisQ46092054
Statins inhibit toll-like receptor 4-mediated lipopolysaccharide signaling and cytokine expressionQ46433219
Prognostic value of activated toll-like receptor-4 in monocytes following acute myocardial infarctionQ46687558
Enhanced expression of TLR4 in smooth muscle cells in human atherosclerotic coronary arteriesQ46878271
Reduced myocardial ischemia-reperfusion injury in toll-like receptor 4-deficient miceQ47200145
Endothelial lipase is increased by inflammation and promotes LDL uptake in macrophages.Q53531751
Toll-like receptor-4 modulates survival by induction of left ventricular remodeling after myocardial infarction in mice.Q54534373
Local Overexpression of Toll-Like Receptors at the Vessel Wall Induces Atherosclerotic Lesion FormationQ58482495
Mechanisms of the priming effect of low doses of lipopoly-saccharides on leukocyte-dependent platelet aggregation in whole bloodQ58831626
Atherosclerotic lesion development and Toll like receptor 2 and 4 responsivenessQ59981259
Toll-Like Receptor 4 Mediates Maladaptive Left Ventricular Remodeling and Impairs Cardiac Function After Myocardial InfarctionQ59981285
Fluvastatin reduces increased blood monocyte Toll-like receptor 4 expression in whole blood from patients with chronic heart failureQ63341226
Mannose binding lectin and soluble Toll-like receptor 2 in heart failure following acute myocardial infarctionQ79255657
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectcardiovascular diseaseQ389735
toll-like receptorQ408004
P304page(s)117-123
P577publication date2009-01-01
P1433published inCardiovascular TherapeuticsQ1871490
P1476titleInnate immunity and toll-like receptor antagonists: a potential role in the treatment of cardiovascular diseases
P478volume27

Reverse relations

cites work (P2860)
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