Toll-like receptor 7 deficiency protects apolipoprotein E-deficient mice from diet-induced atherosclerosis

scientific article

Toll-like receptor 7 deficiency protects apolipoprotein E-deficient mice from diet-induced atherosclerosis is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1084537988
P356DOI10.1038/S41598-017-00977-0
P932PMC publication ID5429799
P698PubMed publication ID28405010

P2093author name stringGuo-Ping Shi
Galina K Sukhova
Cong-Lin Liu
Jin-Ying Zhang
Mengyang Liao
Cleverson Fernandes
Karine Iamarene
Marcela M Santos
P2860cites workEuropean Journal of ImmunologyQ5412727
Human cathepsin S: chromosomal localization, gene structure, and tissue distributionQ24310666
Reduction of atherosclerosis in mice by inhibition of CD40 signallingQ24316540
Recognition of single-stranded RNA viruses by Toll-like receptor 7Q24568101
Unexpected protective role for Toll-like receptor 3 in the arterial wallQ24624935
Matrix metalloproteinase interactions with collagen and elastinQ26996437
The role of pattern-recognition receptors in innate immunity: update on Toll-like receptorsQ27860900
Pathogen recognition and innate immunityQ27861084
Emerging risk biomarkers in cardiovascular diseases and disordersQ28081614
The complement system and toll-like receptors as integrated players in the pathophysiology of atherosclerosisQ28083548
Emerging roles for cysteine proteases in human biologyQ28306260
Reduced atherosclerosis in interleukin-18 deficient apolipoprotein E-knockout miceQ28591350
Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative miceQ34142722
Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for managementQ34181381
Compensatory enlargement of human atherosclerotic coronary arteriesQ34184275
Macrophage expression of active MMP-9 induces acute plaque disruption in apoE-deficient miceQ34236802
Role of toll-like receptor 4 in intimal foam cell accumulation in apolipoprotein E-deficient miceQ34555906
Cathepsin L activity controls adipogenesis and glucose toleranceQ34654358
Elastin degradation and vascular smooth muscle cell phenotype change precede cell loss and arterial medial calcification in a uremic mouse model of chronic kidney diseaseQ34755816
Measurement of matrix metalloproteinase 9-mediated collagen type III degradation fragment as a marker of skin fibrosisQ34769928
TLR7 and CD40 cooperate in IL-6 production via enhanced JNK and AP-1 activation.Q40019462
Engagement of TLR3, TLR7, and NKG2D regulate IFN-gamma secretion but not NKG2D-mediated cytotoxicity by human NK cells stimulated with suboptimal doses of IL-12.Q40084538
Quantitative analysis and characterization of atherosclerotic lesions in the murine aortic sinusQ40289404
Inhibition of glycosphingolipid synthesis ameliorates atherosclerosis and arterial stiffness in apolipoprotein E-/- mice and rabbits fed a high-fat and -cholesterol diet.Q40578811
Guanosine and its modified derivatives are endogenous ligands for TLR7.Q41195915
Viral RNA in the influenza vaccine may have contributed to the development of ANCA-associated vasculitis in a patient following immunisationQ41371533
Hepatitis C virus RNA localization in human carotid plaquesQ42992549
Active cytomegalovirus replication in patients with coronary diseaseQ43415680
Regulatory T cells prevent plaque disruption in apolipoprotein E-knockout mice.Q43751792
The effect of TLR4/7 on the TGF-β-induced Smad signal transduction pathway in human keloidQ44259971
HCV infection facilitates asymptomatic carotid atherosclerosis: preliminary report of HCV RNA localization in human carotid plaques.Q44658074
Loss of matrix metalloproteinase-9 or matrix metalloproteinase-12 protects apolipoprotein E-deficient mice against atherosclerotic media destruction but differentially affects plaque growthQ45873353
Increased atherosclerotic lesions and Th17 in interleukin-18 deficient apolipoprotein E-knockout mice fed high-fat dietQ46129274
Toll-like receptor 7 cooperates with IL-4 in activated B cells through antigen receptor or CD38 and induces class switch recombination and IgG1 productionQ46154630
Role of cathepsin S-dependent epithelial cell apoptosis in IFN-gamma-induced alveolar remodeling and pulmonary emphysemaQ46535470
Deletion of angiotensin II type 2 receptor exaggerated atherosclerosis in apolipoprotein E-null miceQ46689553
Bacterial recognition by TLR7 in the lysosomes of conventional dendritic cellsQ47833171
Hyperlipidemia and atherosclerotic lesion development in LDL receptor-deficient mice fed defined semipurified diets with and without cholate.Q51561712
Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge.Q51679983
Toll-like receptor 3 and 4 signalling through the TRIF and TRAM adaptors in haematopoietic cells promotes atherosclerosis.Q51830691
Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology.Q52589485
Protective role for Toll-like receptor-9 in the development of atherosclerosis in apolipoprotein E-deficient mice.Q53072350
Toll-Like Receptor 7 Protects From Atherosclerosis by Constraining “Inflammatory” Macrophage ActivationQ57315829
Blocking Toll-Like Receptors 7 and 9 Reduces Postinterventional Remodeling via Reduced Macrophage Activation, Foam Cell Formation, and MigrationQ63915472
Cathepsin L deficiency reduces diet-induced atherosclerosis in low-density lipoprotein receptor-knockout mice.Q64885339
Herpesvirus infection accelerates atherosclerosis in the apolipoprotein E-deficient mouseQ74172824
Toll pathway-dependent blockade of CD4+CD25+ T cell-mediated suppression by dendritic cellsQ78806915
Natural and synthetic TLR7 ligands inhibit CpG-A- and CpG-C-oligodeoxynucleotide-induced IFN-alpha productionQ79984758
Activation of dendritic cells via TLR7 reduces Foxp3 expression and suppressive function in induced TregsQ83790498
Toll-like receptor 7 stimulation by imiquimod induces macrophage autophagy and inflammation in atherosclerotic plaquesQ84032992
Development and validation of an enzyme-linked immunosorbent assay for the quantification of a specific MMP-9 mediated degradation fragment of type III collagen--A novel biomarker of atherosclerotic plaque remodelingQ84057841
Specific loss of toll-like receptor 2 on bone marrow derived cells decreases atherosclerosis in LDL receptor null miceQ84898284
Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient miceQ34967612
IRF5 deficiency ameliorates lupus but promotes atherosclerosis and metabolic dysfunction in a mouse model of lupus-associated atherosclerosisQ35070231
IL-4 suppresses the responses to TLR7 and TLR9 stimulation and increases the permissiveness to retroviral infection of murine conventional dendritic cellsQ35086719
Decreased vascular smooth muscle cell density in medial degeneration of human abdominal aortic aneurysms.Q35763570
Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzymeQ35796049
Proinflammatory Stimulation of Toll-Like Receptor 9 with High Dose CpG ODN 1826 Impairs Endothelial Regeneration and Promotes Atherosclerosis in MiceQ35889971
Toll-Like Receptor 9 Inactivation Alleviated Atherosclerotic Progression and Inhibited Macrophage Polarized to M1 Phenotype in ApoE-/- MiceQ35898043
Mast cells modulate the pathogenesis of elastase-induced abdominal aortic aneurysms in miceQ36025276
Protective role for TLR4 signaling in atherosclerosis progression as revealed by infection with a common oral pathogenQ36252511
Matrix metalloproteinases regulate migration, proliferation, and death of vascular smooth muscle cells by degrading matrix and non-matrix substratesQ36305029
Allergic Lung Inflammation Aggravates Angiotensin II-Induced Abdominal Aortic Aneurysms in Mice.Q36403301
RNA-associated autoantigens activate B cells by combined B cell antigen receptor/Toll-like receptor 7 engagement.Q36403678
Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids.Q36459911
Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosisQ36638113
Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein EQ36986664
Toll-like receptor 4 deficiency decreases atherosclerosis but does not protect against inflammation in obese low-density lipoprotein receptor-deficient miceQ37108936
TLR3 deficiency protects against collagen degradation and medial destruction in murine atherosclerotic plaquesQ37166308
Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in miceQ37330834
Vessel-specific Toll-like receptor profiles in human medium and large arteriesQ37357843
Collagens in the progression and complications of atherosclerosisQ37368729
Innate immunity and toll-like receptor antagonists: a potential role in the treatment of cardiovascular diseasesQ37474985
Blocking TLR2 activity diminishes and stabilizes advanced atherosclerotic lesions in apolipoprotein E-deficient miceQ37729330
Diet, commensals and the intestine as sources of pathogen-associated molecular patterns in atherosclerosis, type 2 diabetes and non-alcoholic fatty liver disease.Q37858022
Pattern recognition receptors and the innate immune response to viral infectionQ37945230
Functions of TGF-β-exposed plasmacytoid dendritic cells.Q38083330
Toll-like receptors in atherosclerosis: a 'Pandora's box' of advances and controversiesQ38153941
TLR-mediated activation of NK cells and their role in bacterial/viral immune responses in mammalsQ38173691
Toll-like receptor signaling pathwaysQ38259564
Vascular smooth muscle cell in atherosclerosisQ38353932
Toll-like receptor 7 promotes the apoptosis of THP-1-derived macrophages through the CHOP-dependent pathway.Q38978156
The activation of TLR7 regulates the expression of VEGF, TIMP1, MMP2, IL-6, and IL-15 in Hela cellsQ39042435
TLR4 antagonist reduces early-stage atherosclerosis in diabetic apolipoprotein E-deficient mice.Q39260793
Increased cytokine response after toll-like receptor stimulation in patients with stable coronary artery diseaseQ39309499
Imiquimod enhances IFN-gamma production and effector function of T cells infiltrating human squamous cell carcinomas of the skinQ39705893
Tumour-derived prostaglandin E and transforming growth factor-beta synergize to inhibit plasmacytoid dendritic cell-derived interferon-alphaQ39753147
Vascular cell responsiveness to Toll-like receptor ligands in carotid atheroma.Q39932147
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjecttoll-like receptorQ408004
atherosclerosisQ12252367
P304page(s)847
P577publication date2017-04-12
P1433published inScientific ReportsQ2261792
P1476titleToll-like receptor 7 deficiency protects apolipoprotein E-deficient mice from diet-induced atherosclerosis
P478volume7

Reverse relations

cites work (P2860)
Q93089064RNAs and RNA-Binding Proteins in Immuno-Metabolic Homeostasis and Diseases
Q99591180The Anti-Inflammatory Effect of Taurine on Cardiovascular Disease
Q93046260Ticagrelor induces paraoxonase-1 (PON1) and better protects hypercholesterolemic mice against atherosclerosis compared to clopidogrel
Q98771780When Innate Immunity Meets Angiogenesis-The Role of Toll-Like Receptors in Endothelial Cells and Pulmonary Hypertension

Search more.