Blocking TLR2 activity diminishes and stabilizes advanced atherosclerotic lesions in apolipoprotein E-deficient mice

scientific article published on 15 July 2013

Blocking TLR2 activity diminishes and stabilizes advanced atherosclerotic lesions in apolipoprotein E-deficient mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/APS.2013.75
P932PMC publication ID4003031
P698PubMed publication ID23852085
P5875ResearchGate publication ID249320849

P2093author name stringXiao-xing Wang
Hui-min Yan
Zhuo-wei Hu
Xiao-xi Lv
Zi-yan Wang
Han-zhi Liu
Jia-ping Wang
Xiao-ming Fu
P2860cites workExpression of toll-like receptors in human atherosclerotic lesions: a possible pathway for plaque activationQ77753940
Inflammation and atherosclerosisQ80015206
Long-term administration of 3-deazaadenosine does not alter progression of advanced atherosclerotic lesions in apolipoprotein E-deficient miceQ80805032
Increased endoplasmic reticulum stress in atherosclerotic plaques associated with acute coronary syndromeQ80819961
Targeting TLR2 attenuates pulmonary inflammation and fibrosis by reversion of suppressive immune microenvironmentQ83089214
TLR 2 induces vascular smooth muscle cell migration through cAMP response element-binding protein-mediated interleukin-6 productionQ85005541
Toll-like receptor signallingQ24570126
Toll-like receptor-2 mediates diet and/or pathogen associated atherosclerosis: proteomic findingsQ27300289
Global and regional burden of disease and risk factors, 2001: systematic analysis of population health dataQ28242645
TLR signalingQ28291637
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stressQ29615495
Toll-like receptor 9-dependent activation by DNA-containing immune complexes is mediated by HMGB1 and RAGEQ29620722
Reduced apoptosis and plaque necrosis in advanced atherosclerotic lesions of Apoe-/- and Ldlr-/- mice lacking CHOP.Q30488194
Increased endothelial expression of Toll-like receptor 2 at sites of disturbed blood flow exacerbates early atherogenic eventsQ33318184
Modulation of atherosclerosis in mice by Toll-like receptor 2Q34063165
Toll-like receptor (TLR) 2 and TLR4 differentially regulate doxorubicin induced cardiomyopathy in mice.Q34342389
Atherogenic lipids and lipoproteins trigger CD36-TLR2-dependent apoptosis in macrophages undergoing endoplasmic reticulum stressQ34346809
TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophages.Q35041384
Endogenous ligands of Toll-like receptorsQ35792678
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Toll-like receptor 2 plays a critical role in the progression of atherosclerosis that is independent of dietary lipids.Q36459911
Multiple roles of Toll-like receptor signaling in atherosclerosisQ36589015
Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonistsQ36811131
Mouse models for atherosclerosis and pharmaceutical modifiers.Q36836487
Innate immunity, macrophage activation, and atherosclerosisQ36938635
Molecular mechanisms of plaque instabilityQ36947974
The toll of Toll-like receptors, especially toll-like receptor 2, on murine atherosclerosisQ37065920
Progression and disruption of advanced atherosclerotic plaques in murine modelsQ37108304
Immune and inflammatory mechanisms of atherosclerosis (*)Q37325024
Macrophage apoptosis in atherosclerosis: consequences on plaque progression and the role of endoplasmic reticulum stressQ37401270
Endoplasmic reticulum stress increases the expression and function of toll-like receptor-2 in epithelial cells.Q39646441
Human heat shock protein 60 stimulates vascular smooth muscle cell proliferation through Toll-like receptors 2 and 4.Q40255422
Pathogen-mediated inflammatory atherosclerosis is mediated in part via Toll-like receptor 2-induced inflammatory responses.Q41862930
Toll-like receptor-2 mediates inflammation and matrix degradation in human atherosclerosisQ42641324
The endoplasmic reticulum stress-C/EBP homologous protein pathway-mediated apoptosis in macrophages contributes to the instability of atherosclerotic plaques.Q42961940
Toll-like receptor 2 stimulation induces intimal hyperplasia and atherosclerotic lesion developmentQ46380675
Melagatran reduces advanced atherosclerotic lesion size and may promote plaque stability in apolipoprotein E-deficient miceQ47320668
Apoptosis of vascular smooth muscle cells induces features of plaque vulnerability in atherosclerosis.Q53606830
Advanced atherosclerotic lesions in the innominate artery of the ApoE knockout mouseQ73295343
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectatherosclerosisQ12252367
P304page(s)1025-1035
P577publication date2013-07-15
P1433published inActa Pharmacologica SinicaQ15749885
P1476titleBlocking TLR2 activity diminishes and stabilizes advanced atherosclerotic lesions in apolipoprotein E-deficient mice
P478volume34