The activation of TLR7 regulates the expression of VEGF, TIMP1, MMP2, IL-6, and IL-15 in Hela cells

scientific article published on 18 December 2013

The activation of TLR7 regulates the expression of VEGF, TIMP1, MMP2, IL-6, and IL-15 in Hela cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S11010-013-1925-Y
P698PubMed publication ID24347177

P2093author name stringSheng-Quan Zhang
Lei Li
Fang Wang
Xin Luo
Bo Jia
Feng-Wei Cheng
P2860cites workHuman TLR7 or TLR8 independently confer responsiveness to the antiviral compound R-848Q24298297
Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8Q24310398
Generation of secretable and nonsecretable interleukin 15 isoforms through alternate usage of signal peptidesQ24647708
A human homologue of the Drosophila Toll protein signals activation of adaptive immunityQ28131769
Imiquimod applied topically: a novel immune response modifier and new class of drugQ28140002
Interleukin 15 as a promising candidate for tumor immunotherapyQ28236508
Review Article Imiquimod applied topically: a novel immune response modifier and new class of drugQ29396548
Human papillomavirus is a necessary cause of invasive cervical cancer worldwideQ29617514
Cloning and characterization of a sub-family of human toll-like receptors: hTLR7, hTLR8 and hTLR9.Q33920505
Toll-like receptor 4 signaling in liver injury and hepatic fibrogenesisQ34321742
Cytotoxic T lymphocytes: all roads lead to deathQ34716318
Tumour growth inhibition by an imidazoquinoline is associated with c-Myc down-regulation in urothelial cell carcinomaQ34744159
Host innate immune receptors and beyond: making sense of microbial infectionsQ34785533
Imiquimod and the imidazoquinolones: mechanism of action and therapeutic potentialQ35015851
Overexpression of TLR3, TLR4, TLR7 and TLR9 in esophageal squamous cell carcinomaQ35235996
Toll-like receptors, inflammation and cancerQ36254028
Toll-like receptor 7 regulates pancreatic carcinogenesis in mice and humansQ36357873
Toll-like receptor agonists in the treatment of chronic lymphocytic leukemiaQ36635059
Toll-like receptors: key activators of leucocytes and regulator of haematopoiesis.Q36952605
TLR signaling by tumor and immune cells: a double-edged swordQ37051027
The use of TLR7 and TLR8 ligands for the enhancement of cancer immunotherapyQ37243188
Papillomaviruses in the causation of human cancers - a brief historical accountQ37365856
The TLR7 agonists imiquimod and gardiquimod improve DC-based immunotherapy for melanoma in miceQ37728656
Important aspects of Toll-like receptors, ligands and their signaling pathwaysQ37769153
The role of interleukin-6 in gynaecological malignancies.Q38048977
Role of phosphoinositide 3-kinase in activation of ras and mitogen-activated protein kinase by epidermal growth factorQ39551502
Osteopontin promotes hepatocellular carcinoma invasion by up-regulating MMP-2 and uPA expressionQ39628244
Impaired expression and function of toll-like receptor 7 in hepatitis C virus infection in human hepatoma cellsQ39788612
PTEN regulates angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cellsQ39852386
Toll-like receptor 7 and MyD88 knockdown by lentivirus-mediated RNA interference to porcine dendritic cell subsets.Q40165149
Tumor-selective induction of apoptosis and the small-molecule immune response modifier imiquimodQ42445719
Hepatocyte growth factor protects endothelial progenitor cell from damage of low-density lipoprotein cholesterol via the PI3K/Akt signaling pathwayQ43291021
Toll-like receptor-7 tolerizes malignant B cells and enhances killing by cytotoxic agentsQ43881315
Tissue-specific mRNA expression profiles of human toll-like receptors and related genesQ44407781
MMP-2 and TIMP-1 are derived from, not in response to, pancreatic cancerQ45882622
Type IV collagenase (matrix metalloproteinase-2 and -9) in prostate cancer.Q54702586
Association between Toll-Like Receptor Gene Cluster (TLR6, TLR1, and TLR10) and Prostate CancerQ58033496
Imbalance of expression of matrix metalloproteinases (MMPs) and tissue inhibitors of the matrix metalloproteinases (TIMPs) in human pancreatic carcinomaQ73828612
Amentoflavone inhibits experimental tumor metastasis through a regulatory mechanism involving MMP-2, MMP-9, prolyl hydroxylase, lysyl oxidase, VEGF, ERK-1, ERK-2, STAT-1, NM23 and cytokines in lung tissues of C57BL/6 miceQ81753761
Regulation of Toll-like receptor-induced chemokine production in murine dendritic cells by mitogen-activated protein kinasesQ84184149
P433issue1-2
P921main subjecttoll-like receptorQ408004
P304page(s)43-49
P577publication date2013-12-18
P1433published inMolecular and Cellular BiochemistryQ1573176
P1476titleThe activation of TLR7 regulates the expression of VEGF, TIMP1, MMP2, IL-6, and IL-15 in Hela cells
P478volume389

Reverse relations

cites work (P2860)
Q40145775Condition responsive nanoparticles for managing infection and inflammation in keratitis.
Q54094657Effect of TLR4 on the growth of SiHa human cervical cancer cells via the MyD88-TRAF6-TAK1 and NF-κB-cyclin D1-STAT3 signaling pathways.
Q37734788Inhibition of the TGFβ signalling pathway by cGMP and cGMP-dependent kinase I in renal fibrosis
Q37665498Lipid rafts promote liver cancer cell proliferation and migration by up-regulation of TLR7 expression
Q37012686Nucleic acid-sensing toll-like receptors 3, 7 and 8 in esophageal epithelium, barrett's esophagus, dysplasia and adenocarcinoma
Q41228349Progression of pathology in PINK1-deficient mouse brain from splicing via ubiquitination, ER stress, and mitophagy changes to neuroinflammation
Q33678336Toll-like receptor 7 deficiency protects apolipoprotein E-deficient mice from diet-induced atherosclerosis