Reduction of atherosclerosis in mice by inhibition of CD40 signalling

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Reduction of atherosclerosis in mice by inhibition of CD40 signalling is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1029026219
P356DOI10.1038/28204
P3181OpenCitations bibliographic resource ID1865470
P698PubMed publication ID9671306

P2093author name stringG K Sukhova
P Libby
E Atkinson
F Mach
U Schönbeck
P2860cites workThe pathogenesis of atherosclerosis: a perspective for the 1990sQ29547827
Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene deliveryQ29615235
Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptorsQ34263181
Lewis A. Conner Memorial Lecture. Mechanisms leading to myocardial infarction: insights from studies of vascular biologyQ34308581
CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression.Q34324146
CD40/CD40 ligand interactions are required for T cell-dependent production of interleukin-12 by mouse macrophagesQ34732969
Functional CD40 ligand is expressed on human vascular endothelial cells, smooth muscle cells, and macrophages: implications for CD40-CD40 ligand signaling in atherosclerosisQ36028683
T and B lymphocytes play a minor role in atherosclerotic plaque formation in the apolipoprotein E-deficient mouseQ36142970
Functional interactions of T cells with endothelial cells: the role of CD40L-CD40-mediated signalsQ36365548
The pathogenesis of coronary artery disease and the acute coronary syndromes (1).Q36728740
Absence of P-selectin delays fatty streak formation in miceQ37364649
CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosisQ37696199
Immune regulation by CD40 and its ligand GP39.Q41039754
Expression of functional CD40 by vascular endothelial cellsQ41981036
Localization of T lymphocytes and macrophages in fibrous and complicated human atherosclerotic plaquesQ44793358
Activation of monocyte/macrophage functions related to acute atheroma complication by ligation of CD40: induction of collagenase, stromelysin, and tissue factor.Q52526594
Regulation of matrix metalloproteinase expression in human vascular smooth muscle cells by T lymphocytes: a role for CD40 signaling in plaque rupture?Q52527039
Long-term acceptance of skin and cardiac allografts after blocking CD40 and CD28 pathwaysQ56908985
Lymphocyte populations in atherosclerotic lesions of apoE -/- and LDL receptor -/- mice. Decreasing density with disease progressionQ71231739
Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40Q72093299
Impairment of excitatory amino acid transporter activity by oxidative stress conditions in retinal cells: effect of antioxidantsQ73088182
Blockade of the CD40-CD40 ligand pathway potentiates the capacity of donor-derived dendritic cell progenitors to induce long-term cardiac allograft survivalQ74015557
Are we mortgaging the medical profession?Q95814757
P433issue6689
P407language of work or nameEnglishQ1860
P921main subjectatherosclerosisQ12252367
P304page(s)200-3
P577publication date1998-07-09
P1433published inNatureQ180445
P1476titleReduction of atherosclerosis in mice by inhibition of CD40 signalling
P478volume394

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cites work (P2860)
Q41824616A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation
Q34416243A journey in science: medical scientist in translation
Q37765287A timely diagnosis of myocardial infarction.
Q38737500ATVB Distinguished Scientist Award: How Costimulatory and Coinhibitory Pathways Shape Atherosclerosis
Q37407750Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis.
Q34601733Accelerated atherosclerosis: an extraarticular feature of rheumatoid arthritis?
Q37277926Acute coronary syndromes: from the laboratory markers to the coronary vessels
Q37866627Adaptive immunity in atherosclerosis: mechanisms and future therapeutic targets
Q35581561Adhesion molecules and atherosclerosis
Q34368686Advances in experimental dyslipidemia and atherosclerosis
Q33903180Angiotensin II regulates cellular immune responses through a calcineurin-dependent pathway
Q73086611Anti-atherogenic effect of coenzyme Q10 in apolipoprotein E gene knockout mice
Q34790028Anti-beta 2-glycoprotein I autoantibodies and atherosclerosis
Q38349757Anti-inflammatory therapies for atherosclerosis
Q58481433Antiplatelet drugs
Q73355679Aortic recruitment of blood lymphocytes is most pronounced in early stages of lesion formation in apolipoprotein-E-deficient mice
Q88235115Association of CD40 Gene Polymorphisms with Susceptibility to Neuromyelitis Optica Spectrum Disorders
Q83921113Association of soluble CD40 ligand with carotid atherosclerosis in Japanese type 1 diabetic patients
Q79978197Asymptomatic kindred of patients with coronary events have increased peripheral T-cell activities
Q37378106Atherosclerosis in autoimmune diseases
Q29618972Atherosclerosis. the road ahead
Q36216095Atherosclerosis: the emerging role of inflammation and the CD40-CD40 ligand system
Q35063770Atherosclerotic plaque formation and risk factors
Q33694775Atherosclerotic plaque rupture: emerging insights and opportunities
Q35788328Augmented expression of cyclooxygenase-2 in human atherosclerotic lesions
Q37283009Autoimmune-mediated atherothrombosis
Q28710388Autoreactive HSP60 epitope-specific T-cells in early human atherosclerotic lesions
Q93052209B Cell and CD4 T Cell Interactions Promote Development of Atherosclerosis
Q34618889Basic science review: Statin therapy--Part I: The pleiotropic effects of statins in cardiovascular disease
Q35144122Beta3 integrin deficiency promotes atherosclerosis and pulmonary inflammation in high-fat-fed, hyperlipidemic mice
Q35808632Beyond cholesterol--inflammatory cytokines, the key mediators in atherosclerosis
Q35795164Binding of CD40L to Mac-1's I-domain involves the EQLKKSKTL motif and mediates leukocyte recruitment and atherosclerosis--but does not affect immunity and thrombosis in mice
Q35938537Biomarkers of cardiac disease
Q55175817Biomimetic nanoparticles for inflammation targeting.
Q38972708Blockade of CD40-TRAF2,3 or CD40-TRAF6 is sufficient to inhibit pro-inflammatory responses in non-haematopoietic cells
Q35161070Both early and delayed anti-CD40L antibody treatment induces a stable plaque phenotype
Q33843636C-reactive protein, inflammation, and coronary risk
Q79299389C-reactive protein, inflammation, and coronary risk
Q35787847CD1 expression in human atherosclerosis. A potential mechanism for T cell activation by foam cells
Q35176320CD154 transcriptional regulation in primary human CD4 T cells
Q40919282CD154-CD40 T-cell co-stimulation pathway is a key mechanism in kidney ischemia-reperfusion injury
Q50089678CD27 co-stimulation increases the abundance of regulatory T cells and reduces atherosclerosis in hyperlipidaemic mice.
Q40256254CD40 Generation 2.5 Antisense Oligonucleotide Treatment Attenuates Doxorubicin-induced Nephropathy and Kidney Inflammation.
Q28166057CD40 Ligand-Dependent Maturation of Human Monocyte-Derived Dendritic Cells by Activated Platelets
Q47626387CD40 and CD40L expression in the chicken embryo aorta: possible role in the endothelial-mesenchymal transdifferentiation process
Q36836306CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance
Q48415768CD40 expressed by human brain endothelial cells regulates CD4+ T cell adhesion to endothelium.
Q26752784CD40 in coronary artery disease: a matter of macrophages?
Q34005419CD40 is essential in the upregulation of TRAF proteins and NF-kappaB-dependent proinflammatory gene expression after arterial injury
Q28288474CD40 ligand as a potential biomarker for atherosclerotic instability
Q52949259CD40 ligand is selectively expressed on CD4+ T cells and platelets: implications for CD40–CD40L signalling in atherosclerosis
Q30441065CD40 ligand promotes Mac-1 expression, leukocyte recruitment, and neointima formation after vascular injury
Q43129374CD40 ligand shedding is regulated by interaction between matrix metalloproteinase-2 and platelet integrin alpha(IIb)beta(3).
Q35793488CD40 ligation induces tissue factor expression in human vascular smooth muscle cells
Q37111264CD40 promotes MHC class II expression on adipose tissue macrophages and regulates adipose tissue CD4+ T cells with obesity.
Q34919840CD40 promotes the development of early diabetic retinopathy in mice
Q35788667CD40-CD40 ligand disruption does not prevent hyperoxia-induced injury
Q38042321CD40-CD40L: linking pancreatic, adipose tissue and vascular inflammation in type 2 diabetes and its complications
Q35879683CD40-TRAF Signaling Upregulates CX3CL1 and TNF-α in Human Aortic Endothelial Cells but Not in Retinal Endothelial Cells
Q44362136CD40-dependent activation of phosphatidylinositol 3-kinase/Akt pathway mediates endothelial cell survival and in vitro angiogenesis.
Q37138961CD40/CD40L contributes to hypercholesterolemia-induced microvascular inflammation
Q33814059CD40L and Its Receptors in Atherothrombosis-An Update
Q34193651CD40L deficiency attenuates diet-induced adipose tissue inflammation by impairing immune cell accumulation and production of pathogenic IgG-antibodies
Q79116704Can we stabilize unstable plaque?
Q24568066Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis
Q35197222Cardiovascular complications in inflammatory bowel disease.
Q36809182Cardiovascular disease, inflammation, and periodontal infection
Q28245234Cathepsin G activity lowers plasma LDL and reduces atherosclerosis
Q35544330Cellular adhesion molecules and cardiovascular disease. Part II. Their association with conventional and emerging risk factors, acute coronary events and cardiovascular risk prediction
Q46694569Chemical analysis of atherosclerotic plaque cholesterol combined with histology of the same tissue
Q58246532Chemokines and atherosclerosis
Q37874834Chlamydia pneumoniae infection significantly exacerbates aortic atherosclerosis in an LDLR-/- mouse model within six months.
Q37035672Clinical correlates, heritability, and genetic linkage of circulating CD40 ligand in the Framingham Offspring Study
Q28218124Clinical evidence for anti-inflammatory effects of antiplatelet therapy in patients with atherothrombotic disease
Q43581222Clinical significance of brachial flow-mediated dilation in patients with rheumatoid arthritis
Q42725474Clopidogrel for the hot patient
Q35181668Contact-dependent signaling during the late events of platelet activation.
Q36491362Control of canonical NF-kappaB activation through the NIK-IKK complex pathway
Q38025388Control of dichotomic innate and adaptive immune responses by artery tertiary lymphoid organs in atherosclerosis.
Q37429889Cytokine network and T cell immunity in atherosclerosis
Q28570672Cytokine-inducible CD40 gene expression in vascular smooth muscle cells is mediated by nuclear factor kappaB and signal transducer and activation of transcription-1
Q34967612Deficiency of cathepsin S reduces atherosclerosis in LDL receptor-deficient mice
Q33656103Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile
Q89976448Development of Fractalkine-Targeted Nanofibers that Localize to Sites of Arterial Injury
Q24563090Differential expression of three T lymphocyte-activating CXC chemokines by human atheroma-associated cells
Q36524547Disruption of TGF-β signaling in T cells accelerates atherosclerosis
Q21285000Diverse roles of macrophages in atherosclerosis: from inflammatory biology to biomarker discovery
Q35133174Dynamic changes in regulatory T cells are linked to levels of diet-induced hypercholesterolemia
Q30405805Dysregulated CD4+ T cells from SLE-susceptible mice are sufficient to accelerate atherosclerosis in LDLr-/- mice
Q28214364Effects of VasoCare therapy on the initiation and progression of atherosclerosis
Q63560435Efficacy and safety assessment of a TRAF6-targeted nanoimmunotherapy in atherosclerotic mice and non-human primates
Q37361364Elevated frequencies of circulating Th22 cell in addition to Th17 cell and Th17/Th1 cell in patients with acute coronary syndrome
Q46820939Elevated release of sCD40L from platelets of diabetic patients by thrombin, glucose and advanced glycation end products
Q43939775Elevated soluble CD40 ligand is related to the endothelial adhesion molecules in patients with acute coronary syndrome
Q34455024Endogenous heparin activity deficiency: the 'missing link' in atherogenesis?
Q43977294Endothelial cell and cAMP regulation of T-cell CD40 ligand: relevance of calcium/calmodulin-dependent kinase IV signalling
Q46469540Enhanced soluble CD40 ligand contributes to endothelial cell dysfunction in vitro and monocyte activation in patients with diabetes mellitus: effect of improved metabolic control.
Q51813174Enhanced soluble CD40L in patients with the metabolic syndrome: Relationship with in vivo thrombin generation.
Q37576750Experimental immunotherapeutic approaches for atherosclerosis.
Q37167792Experimental models investigating the inflammatory basis of atherosclerosis
Q42857233Expression and cellular localization of the CC chemokines PARC and ELC in human atherosclerotic plaques
Q56906591Expression of CD40 and its ligand, CD40L, in intestinal lesions of Crohn's disease
Q73344118Expression of CD40 in vascular smooth muscle cells and macrophages is associated with early development of human atherosclerotic lesions
Q35747016Expression of interleukin-15 in mouse and human atherosclerotic lesions
Q36367835Expression of stromelysin-3 in atherosclerotic lesions: regulation via CD40-CD40 ligand signaling in vitro and in vivo
Q73667820Function of CD40/CD40L in peritubular capillary of renal allograft rejection
Q40025338Functional analysis of a tripartite stability element within the CD40 ligand 3' untranslated region
Q33762089Functionality of specific immunity in atherosclerosis
Q36753593Future innovations in anti-platelet therapies.
Q45237822GPIIb-IIIa antagonists reduce thromboinflammatory processes in patients with acute coronary syndromes undergoing percutaneous coronary intervention
Q35975437Genetic basis of atherosclerosis: insights from mice and humans
Q34080318Genetic modifiers of atherosclerosis in mice
Q36691050Genetically programmed biases in Th1 and Th2 immune responses modulate atherogenesis
Q43596820Geneva Biology of Ageing Workshop 2000: phagocytes, inflammation, and ageing
Q35551274High titres of serum antinuclear antibodies, mostly directed against nucleolar antigens, are associated with the presence of coronary atherosclerosis
Q37983656Humoral and cellular immune responses in atherosclerosis: spotlight on B- and T-cells
Q52938547IFN-alpha enhances CD40 ligand-mediated activation of immature monocyte-derived dendritic cells.
Q42556810Identification of primary retinal cells and ex vivo detection of proinflammatory molecules using flow cytometry
Q37699812Imbalance between endothelial damage and repair: a gateway to cardiovascular disease in systemic lupus erythematosus.
Q37325024Immune and inflammatory mechanisms of atherosclerosis (*)
Q34006304Immunological responses to oxidized LDL.
Q35753555Immunomodulation and vaccination for atherosclerosis
Q35172183Immunomodulation for treatment and prevention of atherosclerosis
Q33890414Immunomodulation of atherosclerosis: myth and reality.
Q35994774Immunotherapy targeting the CD40/CD154 costimulatory pathway for treatment of autoimmune disease
Q31132267Impact of glutathione peroxidase-1 deficiency on macrophage foam cell formation and proliferation: implications for atherogenesis
Q37307577Impact of high fat diet on long non-coding RNAs and messenger RNAs expression in the aortas of ApoE(-/-) mice
Q58796242Implication of miR-612 and miR-1976 in the regulation of TP53 and CD40 and their relationship in the response to specific weight-loss diets
Q57718046Increased concentrations of soluble CD40 ligand may help to identify type 1 diabetic adolescents and young adults at risk for developing persistent microalbuminuria
Q44854404Increased soluble CD40 ligand levels in cystic fibrosis
Q33183763Induction of cyclooxygenase-2 and enhanced release of prostaglandin E(2) and I(2) in human endothelial cells by engagement of CD40.
Q34107230Inflammation and immune response in atherosclerosis
Q38083555Inflammation and immune system interactions in atherosclerosis
Q33871329Inflammation, infection and atherosclerosis: do antibacterials have a role in the therapy of coronary artery disease?
Q35549285Inflammation-mediated rheumatic diseases and atherosclerosis
Q39062398Inflammation: A Novel Therapeutic Target/Direction in Atherosclerosis.
Q33805176Inflammatory and autoimmune reactions in atherosclerosis and vaccine design informatics
Q34941391Inflammatory bio-markers and cardiovascular risk prediction
Q35160907Inhibition of CD40 signaling limits evolution of established atherosclerosis in mice
Q34960144Inhibition of plaque neovascularization reduces macrophage accumulation and progression of advanced atherosclerosis
Q34986341Innate and acquired immunity in atherogenesis
Q33659705Innate and adaptive immunity in atherosclerosis
Q47222500Insulin-Like Growth Factor 1 in the Cardiovascular System.
Q34360578Integrin tyrosine phosphorylation in platelet signaling
Q59064332Interferon-γ elicits arteriosclerosis in the absence of leukocytes
Q28771509Interleukin 18 function in atherosclerosis is mediated by the interleukin 18 receptor and the Na-Cl co-transporter
Q47599422Interleukin-1 Beta as a Target for Atherosclerosis Therapy: Biological Basis of CANTOS and Beyond
Q38023144Intimal hyperplasia: slow but deadly
Q36359710Intravenous immunoglobulin and atherosclerosis
Q51959245Inverse correlation between soluble CD40 ligand and soluble CD40 is absent in patients with unstable angina.
Q35787744Kruppel-Like Factor 2-Mediated Suppression of MicroRNA-155 Reduces the Proinflammatory Activation of Macrophages
Q80693835Leptin induces CD40 expression through the activation of Akt in murine dendritic cells
Q36072647Lymphocytes are important in early atherosclerosis
Q33184773MCMV infection increases early T-lymphocyte influx in atherosclerotic lesions in apoE knockout mice
Q34236802Macrophage expression of active MMP-9 induces acute plaque disruption in apoE-deficient mice
Q80422792Mast cells promote atherosclerosis by releasing proinflammatory cytokines
Q34655385Matrix metalloproteinases and atherosclerotic plaque instability
Q35602333Mechanisms of Nifedipine-Downregulated CD40L/sCD40L Signaling in Collagen Stimulated Human Platelets
Q37072381Mechanisms of disease: macrophage migration inhibitory factor in SLE, RA and atherosclerosis
Q33835268Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis
Q74702825Metabolism of oxidized and chemically modified low density lipoproteins in rainbow trout--clearance via scavenger receptors
Q39454807Metabolism-associated danger signal-induced immune response and reverse immune checkpoint-activated CD40+ monocyte differentiation
Q34630514Microvascular thrombosis and CD40/CD40L signaling
Q34160242Minding the gaps to promote thrombus growth and stability
Q36209119Molecular aspects of thrombosis and antithrombotic drugs
Q33946830Molecular link between cholesterol, cytokines and atherosclerosis
Q34772143Monocyte accumulation in mouse atherogenesis is progressive and proportional to extent of disease
Q38176479Monocyte and macrophage differentiation: circulation inflammatory monocyte as biomarker for inflammatory diseases
Q52541865Multiple mechanisms of thrombosis complicating atherosclerotic plaques.
Q57839864Mycophenolate mofetil as an immunomodulatory silver bullet in atherogenesis?
Q36385620Myocardial infarction mediated by endothelin receptor signaling in hypercholesterolemic mice
Q93106450Na+-H+ exchanger 1 determines atherosclerotic lesion acidification and promotes atherogenesis
Q36375728Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells.
Q28211342New Markers of Inflammation and Endothelial Cell Activation
Q43182095New frontiers for platelet CD154.
Q34787127Normal Th1 development following long-term therapeutic blockade of CD154-CD40 in experimental autoimmune encephalomyelitis
Q46212010Novel role of the CXC chemokine receptor 3 in inflammatory response to arterial injury: involvement of mTORC1.
Q36508895Nuclear factor of activated T cells (NFAT) mediates CD154 expression in megakaryocytes
Q37005645Nuclear receptors in macrophages: a link between metabolism and inflammation.
Q28192292Opportunities for the treatment of inflammation in cardiovascular disease
Q31075609Overexpression of TGF-ß1 in macrophages reduces and stabilizes atherosclerotic plaques in ApoE-deficient mice
Q33554184Oxidative risk for atherothrombotic cardiovascular disease
Q37387741Oxidized LDL activates fas-mediated endothelial cell apoptosis
Q36375890P-Selectin or intercellular adhesion molecule (ICAM)-1 deficiency substantially protects against atherosclerosis in apolipoprotein E-deficient mice
Q35838444P-selectin in haemostasis
Q44720878P-selectin, tissue factor and CD40 ligand expression on platelet-leucocyte conjugates in the presence of a GPIIb/IIIa antagonist
Q46840844PARP1 is required for adhesion molecule expression in atherogenesis
Q50848490PKC-epsilon and TLR4 synergistically regulate resistin-mediated inflammation in human macrophages.
Q33183129Patients with acute coronary syndromes express enhanced CD40 ligand/CD154 on platelets.
Q37047173Pharmaceutical stabilization of mast cells attenuates experimental atherogenesis in low-density lipoprotein receptor-deficient mice
Q34647991Plasma concentrations of soluble CD40 ligand in smokers with acute myocardial infarction: a pilot study
Q47645034Platelet CD40 Mediates Leukocyte Recruitment and Neointima Formation after Arterial Denudation Injury in Atherosclerosis-Prone Mice
Q30497499Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis
Q49082878Platelet and monocyte activation in acute ischemic stroke--is there a correlation with stroke etiology?
Q37131719Platelet chemokines in vascular disease
Q37058252Platelet-lymphocyte cross-talk
Q39125083Platelets and von Willebrand factor in atherogenesis
Q34263823Platelets in Inflammation and Thrombosis
Q36328825Platelets in inflammation and atherogenesis.
Q35570940Platelets, atherosclerosis and the endothelium: new therapeutic targets?
Q46367698Preclinical vascular disease in systemic lupus erythematosus and primary antiphospholipid syndrome
Q34795130Proinflammatory responses induced by CD40 in retinal endothelial and Müller cells are inhibited by blocking CD40-Traf2,3 or CD40-Traf6 signaling
Q36452637Proinflammatory, immunomodulating, and prothrombotic properties of anemia and red blood cell transfusions
Q50441470Propolis and swimming in the prevention of atherogenesis and left ventricular hypertrophy in hypercholesterolemic mice.
Q34789613Protective immunity against atherosclerosis carried by B cells of hypercholesterolemic mice
Q44283435Raised serum levels of soluble CD40 ligand in patients with familial hypercholesterolemia: downregulatory effect of statin therapy
Q51550263Re-engineered CD40 receptor enables potent pharmacological activation of dendritic-cell cancer vaccines in vivo.
Q34101903Regulation of CD40 function by its isoforms generated through alternative splicing
Q38396097Regulation of atherosclerotic plaque inflammation
Q28221912Release of biologically active CD154 during collection and storage of platelet concentrates prepared for transfusion
Q52536870Requirement for CD154 in the progression of atherosclerosis.
Q35691984Risk Stratification in Patients with Unstable Angina and Non-ST-elevation Myocardial Infarction
Q64894351Role of CD40 and ADAMTS13 in von Willebrand factor-mediated endothelial cell-platelet-monocyte interaction.
Q35541858Role of Monocytes in Atherogenesis
Q34963016Role of RANKL and RANK in bone loss and arthritis.
Q37080012Role of cell adhesion molecules and immune-cell migration in the initiation, onset and development of atherosclerosis
Q36135534SLE, atherosclerosis and cardiovascular disease
Q37218397Simvastatin reduces circulating plasminogen activator inhibitor 1 activity in volunteers with the metabolic syndrome
Q35633740Soluble CD40 ligand as a predictor of coronary artery disease and long-term clinical outcomes in stable patients undergoing coronary angiography
Q36941078Soluble CD40 ligand induces endothelial dysfunction in human and porcine coronary artery endothelial cells
Q36350146Soluble CD40 ligand induces β 3 integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling
Q51498412Soluble CD40L in patients with morbid obesity: significant reduction after bariatric surgery.
Q37027316Statin treatment for rheumatoid arthritis: a promising novel indication
Q37585835Sympathetic overstimulation during critical illness: adverse effects of adrenergic stress
Q43419630Systemic lupus erythematosus and cardiovascular disease
Q63915433T cell co-stimulation and co-inhibition in cardiovascular disease: a double-edged sword
Q28396774T cell costimulatory and coinhibitory pathways in vascular inflammatory diseases
Q35067512T cell-specific overexpression of TGFß1 fails to influence atherosclerosis in ApoE-deficient mice
Q34108813T cells in the pathogenesis of systemic lupus erythematosus: potential roles of CD154-CD40 interactions and costimulatory molecules
Q37875919T lymphocyte lines isolated from atheromatous plaque contain cells capable of responding to Chlamydia antigens.
Q33819043T-bet deficiency reduces atherosclerosis and alters plaque antigen-specific immune responses
Q40347857T-cell co-stimulators as anti-inflammatory targets for atherosclerotic disease
Q37143018T-cell costimulation and coinhibition in atherosclerosis.
Q36368029TRANCE, a tumor necrosis factor family member critical for CD40 ligand-independent T helper cell activation
Q37494039TWEAK/Fn14 Axis: A Promising Target for the Treatment of Cardiovascular Diseases.
Q49369729Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.
Q38406177Targeting the adaptive immune system: new strategies in the treatment of atherosclerosis
Q92538952The CD40-ATP-P2X 7 Receptor Pathway: Cell to Cell Cross-Talk to Promote Inflammation and Programmed Cell Death of Endothelial Cells
Q37829738The CD40-CD40L system in cardiovascular disease.
Q47245105The CD40-TRAF6 axis is the key regulator of the CD40/CD40L system in neointima formation and arterial remodeling
Q49993738The Interplay of Lipids, Lipoproteins, and Immunity in Atherosclerosis.
Q34054032The Levels of Inflammatory Markers in the Treatment of Stroke study (LIMITS): inflammatory biomarkers as risk predictors after lacunar stroke
Q37560012The Role of Immunogenicity in Cardiovascular Disease
Q40452360The atheroprotective properties of Hsp70: a role for Hsp70-endothelial interactions?
Q92983665The dual role of platelet-innate immune cell interactions in thrombo-inflammation
Q36508676The immune response in atherosclerosis: a double-edged sword
Q34164644The immune system in atherosclerosis
Q27000370The influence of innate and adaptive immune responses on atherosclerosis
Q33814962The initiation of autoimmune diabetes
Q83179418The involvement of the CD40-CD40L pathway in activated platelet-induced changes in HUVEC COX-2 and PPARα expression
Q34020389The levels of soluble CD40 ligand and C-reactive protein in normal weight, overweight and obese people
Q42514630The role of Sp1 and NF-kappa B in regulating CD40 gene expression
Q34207434The role of chemokines in atherosclerosis
Q26996707The role of costimulatory receptors of the tumour necrosis factor receptor family in atherosclerosis
Q46343438The role of monocyte-derived cells and inflammation in baboon ductus arteriosus remodeling
Q48175299The role of monocytosis and neutrophilia in atherosclerosis
Q26801407The role of platelets in the recruitment of leukocytes during vascular disease
Q40393639The use of MCP-1 and soluble CD40 ligand in a pathophysiology-guided approach to the management of coronary artery disease
Q37264355The value of biochemical markers for risk stratification prior to hospital admission in acute chest pain
Q28187576Therapeutic approaches in arterial thrombosis
Q34074837Therapeutic potential of matrix metalloproteinase inhibitors in atherosclerosis
Q33678336Toll-like receptor 7 deficiency protects apolipoprotein E-deficient mice from diet-induced atherosclerosis
Q35542584Towards understanding acute destabilization of vulnerable atherosclerotic plaques
Q52543155Transcriptome analysis reveals a role of interferon-gamma in human neointima formation.
Q33700652Triglyceride-rich lipoproteins: are links with atherosclerosis mediated by a procoagulant and proinflammatory phenotype?
Q34369244Tumor necrosis factor receptor-associated factor 1 (TRAF1) deficiency attenuates atherosclerosis in mice by impairing monocyte recruitment to the vessel wall
Q38294592Upregulation of TRAF-3 by shear stress blocks CD40-mediated endothelial activation
Q35692035Vaccination and atherosclerosis
Q30444108Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice
Q35088517Vascular biology of atherosclerosis: overview and state of the art.
Q30319434Vascular cells contribute to atherosclerosis by cytokine- and innate-immunity-related inflammatory mechanisms
Q34514026Vascular inflammation as a therapeutic target for prevention of cardiovascular disease
Q82893705[Immunological aspects of atherosclerosis]
Q53868946[Interleukin-10 and coronary disease].

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