| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Timothy J. Stalker | Q54107505 |
| P2093 | author name string | Li Zhu | |
| Lawrence F Brass | |||
| P2860 | cites work | PDZ proteins bind, cluster, and synaptically colocalize with Eph receptors and their ephrin ligands | Q22008644 |
| EphrinB ligands recruit GRIP family PDZ adaptor proteins into raft membrane microdomains | Q22009170 | ||
| Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates | Q22010646 | ||
| Biological activity of soluble CD100. II. Soluble CD100, similarly to H-SemaIII, inhibits immune cell migration | Q24290930 | ||
| Coordinate interactions of Csk, Src, and Syk kinases with [alpha]IIb[beta]3 initiate integrin signaling to the cytoskeleton | Q24293554 | ||
| Evidence for a role of ADAM17 (TACE) in the regulation of platelet glycoprotein V | Q24293698 | ||
| Interplay between scatter factor receptors and B plexins controls invasive growth | Q24295561 | ||
| Src kinase activation by direct interaction with the integrin β cytoplasmic domain | Q24298960 | ||
| Characterization of a novel Src-like adapter protein that associates with the Eck receptor tyrosine kinase | Q24307677 | ||
| CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cells | Q24310570 | ||
| Axl receptor tyrosine kinase stimulated by the vitamin K-dependent protein encoded by growth-arrest-specific gene 6 | Q24313270 | ||
| Identification of PVR (CD155) and Nectin-2 (CD112) as cell surface ligands for the human DNAM-1 (CD226) activating molecule | Q24314704 | ||
| Beta 3-endonexin, a novel polypeptide that interacts specifically with the cytoplasmic tail of the integrin beta 3 subunit | Q24316118 | ||
| Analysis of Gas6 in human platelets and plasma | Q46404524 | ||
| Dual regulation of BCR-mediated growth inhibition signaling by CD72. | Q46426359 | ||
| Expression of junctional proteins in human platelets | Q47773034 | ||
| The class IV semaphorin CD100 plays nonredundant roles in the immune system: defective B and T cell activation in CD100-deficient mice. | Q49157483 | ||
| GPVI down-regulation in murine platelets through metalloproteinase-dependent shedding. | Q50889027 | ||
| The inflammatory action of CD40 ligand (CD154) expressed on activated human platelets is temporally limited by coexpressed CD40. | Q52962713 | ||
| CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanism | Q63354517 | ||
| The fine structure of cell contacts in platelet aggregation | Q66963051 | ||
| Characterization of a novel membrane glycoprotein involved in platelet activation | Q69679732 | ||
| Ultrastructural studies of platelet aggregates from human subjects receiving clopidogrel and from a patient with an inherited defect of an ADP-dependent pathway of platelet activation | Q71930733 | ||
| Junctional adhesion molecule (JAM) is phosphorylated by protein kinase C upon platelet activation | Q73067244 | ||
| Release of a product of growth arrest-specific gene 6 from rat platelets | Q73387668 | ||
| Ras-dependent mitogen-activated protein kinase activation by G protein-coupled receptors. Convergence of Gi- and Gq-mediated pathways on calcium/calmodulin, Pyk2, and Src kinase | Q73541784 | ||
| CD154 (CD40 ligand)-deficient mice exhibit prolonged bleeding time and decreased shear-induced platelet aggregates | Q73690749 | ||
| Functional soluble CD100/Sema4D released from activated lymphocytes: possible role in normal and pathologic immune responses | Q73919451 | ||
| Beta3 tyrosine phosphorylation in alphaIIbbeta3 (platelet membrane GP IIb-IIIa) outside-in integrin signaling | Q74314932 | ||
| Tyrosine phosphorylation of the beta3 cytoplasmic domain mediates integrin-cytoskeletal interactions | Q74567473 | ||
| Protein kinase C is involved in the regulation of both signaling and adhesion mediated by DNAX accessory molecule-1 receptor | Q77123346 | ||
| P-Selectin and platelet clearance | Q77620636 | ||
| F11-receptor (F11R/JAM) mediates platelet adhesion to endothelial cells: role in inflammatory thrombosis | Q78505148 | ||
| Platelet activation induces metalloproteinase-dependent GP VI cleavage to down-regulate platelet reactivity to collagen | Q80512477 | ||
| Reduction of atherosclerosis in mice by inhibition of CD40 signalling | Q24316540 | ||
| Mechanisms of platelet activation by a stimulatory antibody: cross-linking of a novel platelet receptor for monoclonal antibody F11 with the FcγRII receptor | Q24528207 | ||
| Characterization of MAX.3 antigen, a glycoprotein expressed on mature macrophages, dendritic cells and blood platelets: identity with CD84 | Q24531986 | ||
| Juxtamembrane tyrosine residues couple the Eph family receptor EphB2/Nuk to specific SH2 domain proteins in neuronal cells | Q24532273 | ||
| Interactions between Eph kinases and ephrins provide a mechanism to support platelet aggregation once cell-to-cell contact has occurred | Q24534800 | ||
| Structure and function of the platelet integrin alphaIIbbeta3 | Q24536159 | ||
| The junctional adhesion molecule 3 (JAM-3) on human platelets is a counterreceptor for the leukocyte integrin Mac-1 | Q24673214 | ||
| SAM as a protein interaction domain involved in developmental regulation | Q24673762 | ||
| PDZ-domain-mediated interaction of the Eph-related receptor tyrosine kinase EphB3 and the ras-binding protein AF6 depends on the kinase activity of the receptor | Q24676972 | ||
| Solution structure of the receptor tyrosine kinase EphB2 SAM domain and identification of two distinct homotypic interaction sites | Q27620261 | ||
| The ligand-binding face of the semaphorins revealed by the high-resolution crystal structure of SEMA4D | Q27641965 | ||
| The crystal structure of an Eph receptor SAM domain reveals a mechanism for modular dimerization | Q27766469 | ||
| Oligomeric structure of the human EphB2 receptor SAM domain | Q27766879 | ||
| Identification of a novel calcium-binding protein that interacts with the integrin alphaIIb cytoplasmic domain | Q28116142 | ||
| Eph receptors and ephrins: regulators of guidance and assembly | Q28139507 | ||
| Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling | Q28140151 | ||
| Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response | Q28179659 | ||
| Platelet CD40 ligand (CD40L)--subcellular localization, regulation of expression, and inhibition by clopidogrel | Q28181620 | ||
| CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells | Q28185503 | ||
| CD84 functions as a homophilic adhesion molecule and enhances IFN-gamma secretion: adhesion is mediated by Ig-like domain 1 | Q28188094 | ||
| Involvement of CD100, a lymphocyte semaphorin, in the activation of the human immune system via CD72: implications for the regulation of immune and inflammatory responses | Q28189775 | ||
| Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology | Q28190296 | ||
| A transmembrane tight junction protein selectively expressed on endothelial cells and platelets | Q28201696 | ||
| The TNF and TNF receptor superfamilies: integrating mammalian biology | Q28203717 | ||
| The JAM family of junctional adhesion molecules | Q28205895 | ||
| Mechanisms and functions of Eph and ephrin signalling | Q28208291 | ||
| Cloning of an immunoglobulin family adhesion molecule selectively expressed by endothelial cells | Q28208656 | ||
| The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals | Q28216283 | ||
| Gas6 receptors Axl, Sky and Mer enhance platelet activation and regulate thrombotic responses | Q28236864 | ||
| Mer receptor tyrosine kinase signaling participates in platelet function | Q28260556 | ||
| Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling | Q28263181 | ||
| Integrins: dynamic scaffolds for adhesion and signaling in platelets | Q28267584 | ||
| Platelet endothelial aggregation receptor 1 (PEAR1), a novel epidermal growth factor repeat-containing transmembrane receptor, participates in platelet contact-induced activation | Q38327516 | ||
| Platelet membrane ultrastructure and its changes during platelet activation | Q39553252 | ||
| Endothelial adhesion molecule ESAM binds directly to the multidomain adaptor MAGI-1 and recruits it to cell contacts | Q40512855 | ||
| Mechanotransduction through growth-factor shedding into the extracellular space | Q40563816 | ||
| Ephrin-B1 Reverse Signaling Activates JNK through a Novel Mechanism That Is Independent of Tyrosine Phosphorylation | Q40653046 | ||
| CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation. | Q40658295 | ||
| The B cell surface protein CD72 recruits the tyrosine phosphatase SHP-1 upon tyrosine phosphorylation. | Q41042524 | ||
| Integrin cytoplasmic tyrosine motif is required for outside-in alphaIIbbeta3 signalling and platelet function | Q41700251 | ||
| Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. | Q41720652 | ||
| Identification of shc as the primary protein binding to the tyrosine-phosphorylated beta 3 subunit of alpha IIbbeta 3 during outside-in integrin platelet signaling | Q41758432 | ||
| Relationships between Rap1b, affinity modulation of integrin alpha IIbbeta 3, and the actin cytoskeleton | Q42815652 | ||
| Platelet endothelial cell adhesion molecule-1 is a negative regulator of platelet-collagen interactions | Q43718540 | ||
| Activation of Syk protein tyrosine kinase through interaction with integrin beta cytoplasmic domains | Q43806424 | ||
| JAM-1 is a ligand of the beta(2) integrin LFA-1 involved in transendothelial migration of leukocytes | Q43867713 | ||
| Engagement of glycoprotein IIb/IIIa (alpha(IIb)beta3) on platelets upregulates CD40L and triggers CD40L-dependent matrix degradation by endothelial cells | Q44179199 | ||
| Signaling by ephrinB1 and Eph kinases in platelets promotes Rap1 activation, platelet adhesion, and aggregation via effector pathways that do not require phosphorylation of ephrinB1. | Q44630316 | ||
| Class IV semaphorins promote angiogenesis by stimulating Rho-initiated pathways through plexin-B. | Q45003993 | ||
| Tumor necrosis factor-alpha-converting enzyme (ADAM17) mediates GPIbalpha shedding from platelets in vitro and in vivo | Q45042577 | ||
| Eph receptors and ligands comprise two major specificity subclasses and are reciprocally compartmentalized during embryogenesis | Q28286738 | ||
| Activation of human platelets by a stimulatory monoclonal antibody | Q28287595 | ||
| Bidirectional signalling through the EPH-family receptor Nuk and its transmembrane ligands | Q28294023 | ||
| The carboxyl terminus of B class ephrins constitutes a PDZ domain binding motif | Q28295434 | ||
| Sema4D induces angiogenesis through Met recruitment by Plexin B1 | Q28301113 | ||
| A novel signaling intermediate, SHEP1, directly couples Eph receptors to R-Ras and Rap1A | Q28507307 | ||
| Ephrin signalling controls brain size by regulating apoptosis of neural progenitors | Q28507499 | ||
| The junction-associated protein AF-6 interacts and clusters with specific Eph receptor tyrosine kinases at specialized sites of cell-cell contact in the brain | Q28567260 | ||
| Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy | Q28584706 | ||
| EphrinB phosphorylation and reverse signaling: regulation by Src kinases and PTP-BL phosphatase | Q28647621 | ||
| Identification of CD72 as a Lymphocyte Receptor for the Class IV Semaphorin CD100 | Q29036802 | ||
| Regulation of the pp72syk protein tyrosine kinase by platelet integrin alpha IIb beta 3 | Q30448362 | ||
| In vivo tyrosine phosphorylation sites of activated ephrin-B1 and ephB2 from neural tissue | Q30996386 | ||
| Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis. | Q31929744 | ||
| Switched at birth: a new family for PECAM-1. | Q31936284 | ||
| Platelet endothelial cell adhesion molecule-1 serves as an inhibitory receptor that modulates platelet responses to collagen | Q32128376 | ||
| Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions | Q33195220 | ||
| Interaction of membrane systems in blood platelets | Q33468112 | ||
| Semaphorin signaling: a little less per-plexin | Q33535176 | ||
| Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development | Q33633524 | ||
| Rap1b is required for normal platelet function and hemostasis in mice | Q33778323 | ||
| The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation | Q33874977 | ||
| Eph kinases and ephrins support thrombus growth and stability by regulating integrin outside-in signaling in platelets. | Q33895889 | ||
| Signalling by semaphorin receptors: cell guidance and beyond. | Q33994985 | ||
| The integrin alpha IIb/beta 3 in human platelet signal transduction | Q34047199 | ||
| The Gas6/Axl system: a novel regulator of vascular cell function | Q34091417 | ||
| Excitatory Eph receptors and adhesive ephrin ligands. | Q34180666 | ||
| Eph receptors and ephrin ligands. essential mediators of vascular development. | Q34204669 | ||
| The anticoagulation factor protein S and its relative, Gas6, are ligands for the Tyro 3/Axl family of receptor tyrosine kinases | Q34319294 | ||
| Integrin tyrosine phosphorylation in platelet signaling | Q34360578 | ||
| EphrinB2 is the entry receptor for Nipah virus, an emergent deadly paramyxovirus | Q34432746 | ||
| The CD100-CD72 interaction: a novel mechanism of immune regulation | Q34460685 | ||
| Ephrins are not only unattractive | Q34612363 | ||
| Platelet activation and the CD40/CD40 ligand pathway: mechanisms and implications for human disease | Q36161310 | ||
| P433 | issue | 12 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 3385-3392 | |
| P577 | publication date | 2005-12-01 | |
| P1433 | published in | Journal of Clinical Investigation | Q3186904 |
| P1476 | title | Minding the gaps to promote thrombus growth and stability | |
| P478 | volume | 115 |
| Q34170393 | A systems approach to hemostasis: 2. Computational analysis of molecular transport in the thrombus microenvironment. |
| Q46098828 | Assaying the efficacy of dual-antiplatelet therapy: use of a controlled-shear-rate microfluidic device with a well-defined collagen surface to track dynamic platelet adhesion |
| Q48270015 | Concentration-dependent effect of hypocalcaemia on in vitro clot strength in patients at risk of bleeding: a retrospective cohort study |
| Q64099185 | Contractile forces in platelet aggregates under microfluidic shear gradients reflect platelet inhibition and bleeding risk |
| Q33277534 | Deficiency of Src homology 2 domain-containing inositol 5-phosphatase 1 affects platelet responses and thrombus growth |
| Q28768968 | Did dinosaurs have megakaryocytes? New ideas about platelets and their progenitors |
| Q30498048 | Diminished contact-dependent reinforcement of Syk activation underlies impaired thrombus growth in mice lacking Semaphorin 4D. |
| Q30494712 | Disruption of SEMA4D ameliorates platelet hypersensitivity in dyslipidemia and confers protection against the development of atherosclerosis |
| Q33501329 | Endothelial cell specific adhesion molecule (ESAM) localizes to platelet-platelet contacts and regulates thrombus formation in vivo |
| Q36654432 | Gene expression profiling of the venom gland from the Venezuelan mapanare (Bothrops colombiensis) using expressed sequence tags (ESTs). |
| Q42182950 | Glycoprotein Ib-IX-V Complex Transmits Cytoskeletal Forces That Enhance Platelet Adhesion |
| Q38840359 | Halting hemorrhage with self-propelling particles and local drug delivery |
| Q38109969 | Harnessing the platelet signaling network to produce an optimal hemostatic response. |
| Q35216740 | Hemolysis exacerbates hyperfibrinolysis, whereas platelolysis shuts down fibrinolysis: evolving concepts of the spectrum of fibrinolysis in response to severe injury |
| Q30537307 | Hierarchical organization in the hemostatic response and its relationship to the platelet-signaling network |
| Q44469988 | Hyperacute direct thrombus imaging using computed tomography and gold nanoparticles |
| Q90691700 | Identification of Injury and Shock Driven Effects on Ex-Vivo Platelet Aggregometry: A Cautionary Tale of Phenotyping |
| Q84005724 | In the shadow of the thrombus |
| Q51047019 | Injectable chitosan-platelet-rich plasma implants to promote tissue regeneration: in vitro properties, in vivo residence, degradation, cell recruitment and vascularization. |
| Q56976747 | Intracellular platelet signalling as a target for drug development |
| Q33815771 | Leukocyte integrin Mac-1 regulates thrombosis via interaction with platelet GPIbα. |
| Q35669517 | Mechanobiology of platelets: techniques to study the role of fluid flow and platelet retraction forces at the micro- and nano-scale |
| Q34796596 | Mice lacking the SLAM family member CD84 display unaltered platelet function in hemostasis and thrombosis |
| Q41646192 | Nonmuscle Myosin IIA Regulates Platelet Contractile Forces Through Rho Kinase and Myosin Light-Chain Kinase |
| Q35967309 | Our expanding view of platelet functions and its clinical implications |
| Q42155974 | Paxillin family members function as Csk-binding proteins that regulate Lyn activity in human and murine platelets |
| Q28200541 | Plasma levels of the growth arrest-specific gene 6 product (Gas6) and antiplatelet drug responsiveness in healthy subjects |
| Q36570485 | Platelet CD36 mediates interactions with endothelial cell-derived microparticles and contributes to thrombosis in mice |
| Q34407634 | Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation |
| Q37807924 | Platelet receptor signaling in thrombus formation |
| Q37032473 | Platelet retraction force measurements using flexible post force sensors |
| Q26820857 | Platelet-based coagulation: different populations, different functions |
| Q28512072 | Platelet-derived S100 family member myeloid-related protein-14 regulates thrombosis |
| Q36950818 | Platelet-derived SDF-1 primes the pulmonary capillary vascular niche to drive lung alveolar regeneration |
| Q35185510 | Premature labor: a state of platelet activation? |
| Q45375279 | Rationale for the selective administration of tranexamic acid to inhibit fibrinolysis in the severely injured patient |
| Q39795377 | Reduced clot retraction rate and altered platelet energy production in patients with asthma |
| Q35616359 | Regulated surface expression and shedding support a dual role for semaphorin 4D in platelet responses to vascular injury |
| Q37903932 | Regulating thrombus growth and stability to achieve an optimal response to injury |
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| Q37784312 | Serglycin proteoglycan deletion in mouse platelets: physiological effects and their implications for platelet contributions to thrombosis, inflammation, atherosclerosis, and metastasis |
| Q36508868 | Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice |
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| Q38106013 | The effects of arterial flow on platelet activation, thrombus growth, and stabilization. |
| Q33397768 | The maternal immune response to fetal platelet GPIbα causes frequent miscarriage in mice that can be prevented by intravenous IgG and anti-FcRn therapies |
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| Q87841178 | The search for new antithrombotic mechanisms and therapies that may spare hemostasis |
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