CD40 expressed by human brain endothelial cells regulates CD4+ T cell adhesion to endothelium

scientific article published in January 2003

CD40 expressed by human brain endothelial cells regulates CD4+ T cell adhesion to endothelium is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0165-5728(02)00423-X
P698PubMed publication ID12507785

P2093author name stringKakuri M Omari
Katerina Dorovini-Zis
P2860cites workRequirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis.Q48913563
Expression and function of the costimulatory molecules B7-1 (CD80) and B7-2 (CD86) in an in vitro model of the human blood--brain barrier.Q49117848
Requirement for CD154 in the progression of atherosclerosis.Q52536870
Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation.Q53338394
A soluble form of TRAP (CD40 ligand) is rapidly released after T cell activationQ71889606
Prevention of collagen-induced arthritis with an antibody to gp39, the ligand for CD40Q72093299
Cytokine regulation of CD40 expression in fetal human astrocyte culturesQ73225523
Resting B lymphocytes as APC for naive T lymphocytes: dependence on CD40 ligand/CD40Q73330354
CD40 engagement stimulates IL-12 p70 production by human microglial cells: basis for Th1 polarization in the CNSQ73336410
CD154 (CD40L) induces human endothelial cell chemokine production and migration of leukocyte subsetsQ73386215
CD40 and CD40 ligand (CD154) are coexpressed on microvessels in vivo in human cardiac allograft rejectionQ74015547
Biological function of CD40 on human endothelial cells: costimulation with CD40 ligand and interleukin-4 selectively induces expression of vascular cell adhesion molecule-1 and P-selectin resulting in preferential adhesion of lymphocytesQ74121901
CD40L-CD40 interactions regulate endothelial cell surface tissue factor and thrombomodulin expressionQ74310001
CD40 expression and function on human dermal microvascular endothelial cells: role in cutaneous inflammationQ74318678
Prevention of experimental autoimmune encephalomyelitis in the common marmoset (Callithrix jacchus) using a chimeric antagonist monoclonal antibody against human CD40 is associated with altered B cell responsesQ74388332
Transient anti-CD154-mediated immunotherapy of ongoing relapsing experimental autoimmune encephalomyelitis induces long-term inhibition of disease relapsesQ74570628
T cell interaction with ICAM-1-deficient endothelium in vitro: essential role for ICAM-1 and ICAM-2 in transendothelial migration of T cellsQ77530674
CD40L (CD154) expression in human liver allografts during chronic ductopenic rejectionQ77748015
CD40 ligation induced phenotypic and functional expression of CD80 by human cardiac microvascular endothelial cellsQ78164667
CD40 expression in human thyroid tissue: evidence for involvement of multiple cell types in autoimmune and neoplastic diseasesQ78245870
CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cellsQ24310570
Reduction of atherosclerosis in mice by inhibition of CD40 signallingQ24316540
Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activationQ24677534
2 A crystal structure of an extracellular fragment of human CD40 ligandQ27732546
CD40-CD40 ligandQ28143324
The CD40/CD154 receptor/ligand dyadQ28202756
Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosisQ33835268
The soluble CD40 ligand sCD154 in systemic lupus erythematosusQ33858548
CD40 is expressed and functional on neuronal cellsQ34085854
Antibody to the ligand of CD40, gp39, blocks the occurrence of the acute and chronic forms of graft-vs-host diseaseQ34186352
CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression.Q34324146
The type 1 receptor (CD120a) is the high-affinity receptor for soluble tumor necrosis factorQ35739690
CD40-CD40L interactions induce chemokine expression by human microglia: implications for human immunodeficiency virus encephalitis and multiple sclerosisQ35747327
T lymphocytes induce endothelial cell matrix metalloproteinase expression by a CD40L-dependent mechanism: implications for tubule formationQ35754623
Surface expression of alpha 4 integrin by CD4 T cells is required for their entry into brain parenchymaQ36361169
Activated T cells induce expression of B7/BB1 on normal or leukemic B cells through a CD40-dependent signalQ36361532
Functional interactions of T cells with endothelial cells: the role of CD40L-CD40-mediated signalsQ36365548
Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor, and interleukin 1.Q36367016
The clinical course of experimental autoimmune encephalomyelitis and inflammation is controlled by the expression of CD40 within the central nervous system.Q36369234
CD40-CD40 ligand interactions in experimental allergic encephalomyelitis and multiple sclerosisQ37696199
Cytokine-inducible CD40 expression in human endothelial cells is mediated by interferon regulatory factor-1.Q38293160
Expression of a 32-kDa ligand for the CD40 antigen on activated human T lymphocytesQ38320708
Following direct CD40 activation, human primary microglial cells produce IL-12 p40 but not bioactive IL-12 p70.Q40805826
Interaction of alpha4-integrin with VCAM-1 is involved in adhesion of encephalitogenic T cell blasts to brain endothelium but not in their transendothelial migration in vitro.Q40907561
Activation of human dendritic cells through CD40 cross-linking.Q41440958
Expression of functional CD40 by vascular endothelial cellsQ41981036
Expression of vascular cell adhesion molecule-1 (VCAM-1) by human brain microvessel endothelial cells in primary cultureQ42477916
Regualtion by cytokines and lipopolysaccharide of E-selectin expression by human brain microvessel endothelial cells in primary culture.Q42522548
Platelet/endothelial cell adhesion molecule-1 (PECAM-1) expression by human brain microvessel endothelial cells in primary cultureQ42525855
Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.Q46007698
Expression of CD40 in the brain of Alzheimer's disease and other neurological diseasesQ46847222
Inhibition of experimental autoimmune encephalomyelitis by an antibody to the intercellular adhesion molecule ICAM-1.Q48245976
In vitro adhesion and migration of T lymphocytes across monolayers of human brain microvessel endothelial cells: regulation by ICAM-1, VCAM-1, E-selectin and PECAM-1.Q48277566
Immunohistochemical analysis of the cellular infiltrate in multiple sclerosis lesionsQ48338419
Upregulation of intercellular adhesion molecule-1 (ICAM-1) expression in primary cultures of human brain microvessel endothelial cells by cytokines and lipopolysaccharideQ48464784
P433issue1-2
P921main subjectendotheliumQ111140
cell adhesionQ187640
P304page(s)166-178
P577publication date2003-01-01
P1433published inJournal of NeuroimmunologyQ15716691
P1476titleCD40 expressed by human brain endothelial cells regulates CD4+ T cell adhesion to endothelium
P478volume134

Reverse relations

cites work (P2860)
Q33746963A PPARγ-dependent miR-424/503-CD40 axis regulates inflammation mediated angiogenesis
Q26745458A Pathophysiological Insight into Sepsis and Its Correlation with Postmortem Diagnosis
Q36001196Abdominal obesity contributes to neurocognitive impairment in HIV-infected patients with increased inflammation and immune activation
Q40377619Blood-brain barrier-specific properties of a human adult brain endothelial cell line
Q36911388CD40 induces anti-Toxoplasma gondii activity in nonhematopoietic cells dependent on autophagy proteins
Q27481468CD40-CD40 Ligand Interactions Promote Trafficking of CD8+ T Cells into the Brain and Protection against West Nile Virus Encephalitis
Q37138961CD40/CD40L contributes to hypercholesterolemia-induced microvascular inflammation
Q36112729Chemokines Referee Inflammation within the Central Nervous System during Infection and Disease
Q42484181Differential expression and regulation of murine CD40 in regional vascular beds
Q34015684Dyad of CD40/CD40 ligand fosters neuroinflammation at the blood-brain barrier and is regulated via JNK signaling: implications for HIV-1 encephalitis
Q34218647Endothelial microparticles interact with and support the proliferation of T cells
Q36396973Immune surveillance of the human central nervous system (CNS): different migration pathways of immune cells through the blood-brain barrier and blood-cerebrospinal fluid barrier in healthy persons
Q55052425Infection of the endothelium by members of the order Rickettsiales.
Q47986213Inflammatory CNS disease caused by immune checkpoint inhibitors: status and perspectives
Q36885184Molecular targets for disrupting leukocyte trafficking during multiple sclerosis
Q36640252Peripheral T-lymphocyte and natural killer cell population imbalance is associated with septic encephalopathy in patients with severe sepsis
Q27307762Rapid copper acquisition by developing murine mesothelioma: decreasing bioavailable copper slows tumor growth, normalizes vessels and promotes T cell infiltration
Q48957653Recombinant erythropoietin down-regulates IL-6 and CXCR4 genes in TNF-alpha-treated primary cultures of human microvascular endothelial cells: implications for multiple sclerosis.
Q37038789Regulation of adaptive immunity by the fractalkine receptor during autoimmune inflammation
Q36912577Reperfusion syndrome: cellular mechanisms of microvascular dysfunction and potential therapeutic strategies
Q28570194Repetitive hyperbaric oxygenation attenuates reactive astrogliosis and suppresses expression of inflammatory mediators in the rat model of brain injury
Q24802170Science review: The brain in sepsis--culprit and victim
Q36780807Sepsis-associated delirium
Q38081497Sepsis-induced brain dysfunction
Q36295987Stroke and T-cells
Q47221242The CD40-CD40L Dyad in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis
Q34548189The brain microvascular endothelium supports T cell proliferation and has potential for alloantigen presentation
Q37635764The link between inflammation, synaptic transmission and neurodegeneration in multiple sclerosis.

Search more.