CD40/CD40L contributes to hypercholesterolemia-induced microvascular inflammation

scientific article published on 26 December 2008

CD40/CD40L contributes to hypercholesterolemia-induced microvascular inflammation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPHEART.00962.2008
P8608Fatcat IDrelease_7tockjggunfste4hhegacxzkim
P932PMC publication ID2660234
P698PubMed publication ID19112095
P5875ResearchGate publication ID23708762

P2093author name stringD Neil Granger
Janice M Russell
Karen Y Stokes
Leshanna Calahan
Candiss M Hamric
P2860cites workCD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cellsQ24310570
Reduction of atherosclerosis in mice by inhibition of CD40 signallingQ24316540
The CD40/CD154 receptor/ligand dyadQ28202756
gp91phox-dependent expression of platelet CD40 ligandQ28208601
Clopidogrel improves systemic endothelial nitric oxide bioavailability in patients with coronary artery disease: evidence for antioxidant and antiinflammatory effectsQ28217555
CD40 ligand promotes Mac-1 expression, leukocyte recruitment, and neointima formation after vascular injuryQ30441065
Upregulation of CD40 and CD40 ligand (CD154) in patients with moderate hypercholesterolemiaQ33183118
CD40 on human endothelial cells: inducibility by cytokines and functional regulation of adhesion molecule expression.Q34324146
Inhibition of CD40 signaling limits evolution of established atherosclerosis in miceQ35160907
Platelet-associated NAD(P)H oxidase contributes to the thrombogenic phenotype induced by hypercholesterolemiaQ35989704
Microvascular responses to hypercholesterolemia: the interactions between innate and adaptive immune responsesQ36566474
Soluble CD40 ligand induces endothelial dysfunction in human and porcine coronary artery endothelial cellsQ36941078
IFN-gamma potentiates atherosclerosis in ApoE knock-out miceQ37368296
CD40 ligand binds to alpha5beta1 integrin and triggers cell signalingQ40191634
CD40 is constitutively expressed on platelets and provides a novel mechanism for platelet activation.Q40658295
CD40 is a cellular receptor mediating mycobacterial heat shock protein 70 stimulation of CC-chemokinesQ40761122
Differential expression and regulation of murine CD40 in regional vascular bedsQ42484181
NAD(P)H oxidase-derived superoxide mediates hypercholesterolemia-induced leukocyte-endothelial cell adhesionQ43542911
T helper-cell phenotype regulates atherosclerosis in mice under conditions of mild hypercholesterolemiaQ43624009
CD40 ligand inhibits endothelial cell migration by increasing production of endothelial reactive oxygen speciesQ44108438
Raised serum levels of soluble CD40 ligand in patients with familial hypercholesterolemia: downregulatory effect of statin therapyQ44283435
Hypercholesterolemia promotes P-selectin-dependent platelet-endothelial cell adhesion in postcapillary venulesQ44342200
Role of Interferon-γ in Hypercholesterolemia-Induced Leukocyte–Endothelial Cell AdhesionQ44403588
Role of interleukin 12 in hypercholesterolemia-induced inflammationQ44542220
Cerebral microvascular responses to hypercholesterolemia: roles of NADPH oxidase and P-selectinQ44690034
Short-term treatment with atorvastatin reduces platelet CD40 ligand and thrombin generation in hypercholesterolemic patientsQ45248514
Neutrophil CD40 enhances platelet-mediated inflammationQ46741873
CD40 expressed by human brain endothelial cells regulates CD4+ T cell adhesion to endotheliumQ48415768
CD154 stimulation of interleukin-12 synthesis in human endothelial cells.Q48747669
CD40 ligand mediates inflammation independently of CD40 by interaction with Mac-1.Q51798890
Requirement for CD154 in the progression of atherosclerosis.Q52536870
CD40 ligand signals optimize T helper cell cytokine production: role in Th2 development and induction of germinal centers.Q52906427
C4b-Binding Protein (C4BP) Activates B Cells through the CD40 ReceptorQ60250685
CD40L stabilizes arterial thrombi by a β3 integrin–dependent mechanismQ63354517
Cutting Edge: Identification of c-Rel-Dependent and -Independent Pathways of IL-12 Production During Infectious and Inflammatory StimuliQ64140403
CD154 (CD40L) induces human endothelial cell chemokine production and migration of leukocyte subsetsQ73386215
Reperfusion-induced leukocyte adhesion and vascular protein leakage in normal and hypercholesterolemic ratsQ73645108
Biological function of CD40 on human endothelial cells: costimulation with CD40 ligand and interleukin-4 selectively induces expression of vascular cell adhesion molecule-1 and P-selectin resulting in preferential adhesion of lymphocytesQ74121901
CD40 expression and function on human dermal microvascular endothelial cells: role in cutaneous inflammationQ74318678
Leukocyte dependence of platelet adhesion in postcapillary venulesQ75235688
The role of T-lymphocytes in hypercholesterolemia-induced leukocyte-endothelial interactionsQ78359558
Low venular shear rates promote leukocyte-dependent recruitment of adherent plateletsQ78396319
Platelet P-selectin facilitates atherosclerotic lesion developmentQ78654773
Myocardial perfusion reserve in cardiovascular magnetic resonance: Correlation to coronary microvascular dysfunctionQ79293780
Estradiol blocks the induction of CD40 and CD40L expression on endothelial cells and prevents neutrophil adhesion: an ERalpha-mediated pathwayQ79782271
Role of platelets in hypercholesterolemia-induced leukocyte recruitment and arteriolar dysfunctionQ79827661
T-cell derived interferon-gamma contributes to arteriolar dysfunction during acute hypercholesterolemiaQ80513022
CD40/CD40L expression in leukocytes from chronic granulomatous disease patientsQ80792647
Hypercholesterolemia promotes leukocyte-dependent platelet adhesion in murine postcapillary venulesQ80929549
CD40 ligand influences platelet release of reactive oxygen intermediatesQ81159667
P433issue3
P921main subjectinflammationQ101991
hypercholesterolemiaQ762713
microvesselQ6840468
P304page(s)H689-97
P577publication date2008-12-26
P1433published inAmerican Journal of Physiology Heart and Circulatory PhysiologyQ3193662
P1476titleCD40/CD40L contributes to hypercholesterolemia-induced microvascular inflammation
P478volume296

Reverse relations

cites work (P2860)
Q64898850Analysis of Genetic Variation in CD40 and CD40L: Relationship with mRNA Relative Expression and Soluble Proteins in Acute Coronary Syndrome.
Q91778340Cardiovascular Comorbidities in Psoriatic Disease
Q43836602Effect of atorvastatin on atherosclerotic plaque formation and platelet activation in hypercholesterolemic rats
Q42740250Effect of resveratrol on platelet activation in hypercholesterolemic rats: CD40-CD40L system as a potential target
Q34375542Hypercholesterolemia and microvascular dysfunction: interventional strategies
Q33848992Hypercholesterolemia and risk of incident psoriasis and psoriatic arthritis in US women
Q87184042Impact of carotid atherosclerosis combined with hypercholesterolemia on cerebral microvessels and brain parenchyma in a new complex rat model
Q36982855Late chronic catechin antioxidant treatment is deleterious to the endothelial function in aging mice with established atherosclerosis.
Q49188523Mechanisms of I/R-Induced Endothelium-Dependent Vasodilator Dysfunction.
Q34766422Microvascular responses to cardiovascular risk factors.
Q37240964Myocardial microvascular function during acute coronary artery stenosis: effect of hypertension and hypercholesterolaemia
Q34860648Parenchymal expression of CD40 exacerbates adenovirus-induced hepatitis in mice.
Q37970013Platelets: a critical link between inflammation and microvascular dysfunction
Q37722903Positron emission tomography imaging for vascular inflammation evaluation in elderly subjects with different risk factors for cardiovascular diseases
Q38688128Psoriatic arthritis: complexities, comorbidities and implications for the clinic
Q43175144Retinal vessel analysis in hypercholesterolemic patients before and after LDL apheresis
Q35586845Serum lipid profiles are associated with disability and MRI outcomes in multiple sclerosis
Q26777192The Contribution of CD40/CD40L Axis in Inflammatory Bowel Disease: An Update
Q83179418The involvement of the CD40-CD40L pathway in activated platelet-induced changes in HUVEC COX-2 and PPARα expression
Q37680428Troubleshooting methods: Using intravital microscopy in drug research
Q37323597mTORC1-Activated Monocytes Increase Tregs and Inhibit the Immune Response to Bacterial Infections.

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