Dysregulated CD4+ T cells from SLE-susceptible mice are sufficient to accelerate atherosclerosis in LDLr-/- mice

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Dysregulated CD4+ T cells from SLE-susceptible mice are sufficient to accelerate atherosclerosis in LDLr-/- mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1136/ANNRHEUMDIS-2013-203759
P932PMC publication ID4083014
P698PubMed publication ID24395554
P5875ResearchGate publication ID259607801

P2093author name stringAmy S Major
Ashley J Wilhelm
Jillian P Rhoads
Nekeithia S Wade
P2860cites workReduction of atherosclerosis in mice by inhibition of CD40 signallingQ24316540
Dicer insufficiency and microRNA-155 overexpression in lupus regulatory T cells: an apparent paradox in the setting of an inflammatory milieuQ24625814
Immune dysregulation accelerates atherosclerosis and modulates plaque composition in systemic lupus erythematosusQ28591255
Blockade of interleukin-17A results in reduced atherosclerosis in apolipoprotein E-deficient miceQ30432644
Low numbers of FOXP3 positive regulatory T cells are present in all developmental stages of human atherosclerotic lesionsQ33294845
T cell hyperactivity in lupus as a consequence of hyperstimulatory antigen-presenting cellsQ33842929
Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosusQ33923351
Prevalence and correlates of accelerated atherosclerosis in systemic lupus erythematosusQ33974679
Premature coronary-artery atherosclerosis in systemic lupus erythematosusQ33974685
Autoimmunity in atherosclerosis. The role of autoantigensQ33976585
Mechanisms of premature atherosclerosis in rheumatoid arthritis and lupusQ34343906
CD40-CD40L interactions in atherosclerosisQ34498144
The NZM2410-derived lupus susceptibility locus Sle2c1 increases Th17 polarization and induces nephritis in fas-deficient miceQ34821636
Interleukin-10 signaling in regulatory T cells is required for suppression of Th17 cell-mediated inflammationQ34936014
Inhibition of CD40 signaling limits evolution of established atherosclerosis in miceQ35160907
Mycophenolate mofetil but not atorvastatin attenuates atherosclerosis in lupus-prone LDLr(-/-) miceQ35835882
Statins induce the accumulation of regulatory T cells in atherosclerotic plaqueQ36071708
Treg-mediated suppression of atherosclerosis requires MYD88 signaling in DCs.Q36497238
Depletion of FOXP3+ regulatory T cells promotes hypercholesterolemia and atherosclerosisQ36638113
Genetically programmed biases in Th1 and Th2 immune responses modulate atherogenesisQ36691050
IL-21 receptor is required for the systemic accumulation of activated B and T lymphocytes in MRL/MpJ-Fas(lpr/lpr)/J miceQ36745302
ICOS costimulation expands Th2 immunity by augmenting migration of lymphocytes to draining lymph nodesQ36921978
Accelerated atherosclerosis is independent of feeding high fat diet in systemic lupus erythematosus-susceptible LDLr(-/-) miceQ37143021
The role of adaptive T cell immunity in atherosclerosisQ37339539
Loss of SOCS3 expression in T cells reveals a regulatory role for interleukin-17 in atherosclerosisQ37377439
The role of IL-23/IL-17 axis in lupus nephritisQ37397437
Are CD4+CD25-Foxp3+ cells in untreated new-onset lupus patients regulatory T cells?Q37454041
Inhibition of arterial lesion progression in CD16-deficient mice: evidence for altered immunity and the role of IL-10.Q37467868
Accelerated atherosclerosis in SLE: mechanisms and prevention approachesQ37658524
Adaptive T cell immune responses and atherogenesisQ37703844
Human FoxP3+ regulatory T cells in systemic autoimmune diseasesQ37881234
Production of congenic mouse strains carrying genomic intervals containing SLE-susceptibility genes derived from the SLE-prone NZM2410 strainQ40941667
Stability of the regulatory T cell lineage in vivo.Q42060265
A critical function of Th17 proinflammatory cells in the development of atherosclerotic plaque in miceQ42856694
The bimodal mortality pattern of systemic lupus erythematosusQ43703475
Risk factors for cardiovascular disease in systemic lupus erythematosusQ43767819
Inhibition of transforming growth factor-beta signaling accelerates atherosclerosis and induces an unstable plaque phenotype in mice.Q43794492
Increased atherosclerotic lesions and Th17 in interleukin-18 deficient apolipoprotein E-knockout mice fed high-fat dietQ46129274
Reduced CD4+,CD25- T cell sensitivity to the suppressive function of CD4+,CD25high,CD127 -/low regulatory T cells in patients with active systemic lupus erythematosusQ46521582
Suppression of disease in New Zealand Black/New Zealand White lupus-prone mice by adoptive transfer of ex vivo expanded regulatory T cellsQ46686118
A subset of CD4+ T cells expressing early activation antigen CD69 in murine lupus: possible abnormal regulatory role for cytokine imbalance.Q47757213
Elevated interleukin-10 levels correlated with disease activity in systemic lupus erythematosusQ47958022
Th17/Treg imbalance induced by increased incidence of atherosclerosis in patients with systemic lupus erythematosus (SLE).Q50864077
Local delivery of IL-2 reduces atherosclerosis via expansion of regulatory T cells.Q52891939
Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4+CD25+ T cells.Q53883439
Activation of Th17/Th1 and Th1, but not Th17, is associated with the acute cardiac event in patients with acute coronary syndrome.Q54375886
Plasma IL-17A is increased in new-onset SLE patients and associated with disease activity.Q54444518
Quantitative and qualitative normal regulatory T cells are not capable of inducing suppression in SLE patients due to T-cell resistance.Q54537170
Inverse correlation between CD4+ regulatory T-cell population and autoantibody levels in paediatric patients with systemic lupus erythematosus.Q54621895
Natural regulatory T cells control the development of atherosclerosis in miceQ58149268
Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout miceQ73288555
Prevalence and risk factors of carotid plaque in women with systemic lupus erythematosusQ77909409
Genetic dissection of SLE pathogenesis: adoptive transfer of Sle1 mediates the loss of tolerance by bone marrow-derived B cellsQ78109916
Dysfunctional CD4+,CD25+ regulatory T cells in untreated active systemic lupus erythematosus secondary to interferon-alpha-producing antigen-presenting cellsQ80800895
MRL/Mp CD4+,CD25- T cells show reduced sensitivity to suppression by CD4+,CD25+ regulatory T cells in vitro: a novel defect of T cell regulation in systemic lupus erythematosusQ81629357
Lupus Atherosclerosis Prevention Study (LAPS)Q82991610
Elevated Th17 cells are accompanied by FoxP3+ Treg cells decrease in patients with lupus nephritisQ83226583
The Th17/Treg functional imbalance during atherogenesis in ApoE(-/-) miceQ84738724
Disturbed Th1, Th2, Th17 and T(reg) balance in patients with systemic lupus erythematosusQ84948994
Interleukin-33 augments Treg cell levels: a flaw mechanism in atherosclerosisQ85566850
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectatherosclerosisQ12252367
P304page(s)778-785
P577publication date2014-01-06
P1433published inAnnals of the Rheumatic DiseasesQ4767876
P1476titleDysregulated CD4+ T cells from SLE-susceptible mice are sufficient to accelerate atherosclerosis in LDLr-/- mice
P478volume74

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cites work (P2860)
Q26744624Breaking Free of Control: How Conventional T Cells Overcome Regulatory T Cell Suppression
Q39216733Epigenetic regulation in monocyte/macrophage: A key player during atherosclerosis
Q64121750Inhibition of IL-17 ameliorates systemic lupus erythematosus in Roquin mice through regulating the balance of TFH cells, GC B cells, Treg and Breg
Q92876890LCK inhibitor attenuates atherosclerosis in ApoE-/- mice via regulating T cell differentiation and reverse cholesterol transport
Q36479452Lupus-Prone Mice Resist Immune Regulation and Transplant Tolerance Induction.
Q60950193The Role of Circulating Regulatory T Cell Levels on Subclinical Atherosclerosis and Cardiovascular Risk Factors in Women with Systemic Lupus Erythematosus
Q40097536The regulation of regulation: IL-10 increases CD4(+) CD25(+) regulatory T cells but impairs their immunosuppressive activity in murine models with schistosomiasis japonica or asthma.

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