LCK inhibitor attenuates atherosclerosis in ApoE-/- mice via regulating T cell differentiation and reverse cholesterol transport

scientific article published on 21 January 2020

LCK inhibitor attenuates atherosclerosis in ApoE-/- mice via regulating T cell differentiation and reverse cholesterol transport is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.YJMCC.2020.01.003
P698PubMed publication ID31972265

P2093author name stringYanan Zhang
Zhigang Guo
Tongwei Wu
Jichen Liu
Wenyan Lai
Zhongzhou Guo
Yusheng Ma
P2860cites workProfound block in thymocyte development in mice lacking p56lckQ24298882
Function of the Src-family kinases, Lck and Fyn, in T-cell development and activationQ28288372
Dysregulated CD4+ T cells from SLE-susceptible mice are sufficient to accelerate atherosclerosis in LDLr-/- miceQ30405805
Cytokines, macrophage lipid metabolism and foam cells: implications for cardiovascular disease therapy.Q33907760
Lck protein tyrosine kinase is a key regulator of T-cell activation and a target for signal intervention by Herpesvirus saimiri and other viral gene productsQ33940330
Cholesterol efflux capacity, high-density lipoprotein function, and atherosclerosisQ34537191
Deleting TCR alpha beta+ or CD4+ T lymphocytes leads to opposite effects on site-specific atherosclerosis in female apolipoprotein E-deficient miceQ35103567
Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets.Q35640438
Cholesterol efflux capacity, macrophage reverse cholesterol transport and cardioprotective HDL.Q36197563
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.Q36693820
Infectious tolerance via the consumption of essential amino acids and mTOR signalingQ37246191
The effects of total lymphocyte deficiency on the extent of atherosclerosis in apolipoprotein E-/- miceQ37372718
Antiinflammatory Therapy with Canakinumab for Atherosclerotic DiseaseQ38606033
The isolation and characterization of murine macrophagesQ39485692
The mTOR kinase differentially regulates effector and regulatory T cell lineage commitmentQ42593305
Sirolimus for the Prevention of In-Stent Restenosis in a Coronary ArteryQ44605351
New anti-monocyte chemoattractant protein-1 gene therapy attenuates atherosclerosis in apolipoprotein E-knockout miceQ45876621
Monocyte-Macrophages and T Cells in AtherosclerosisQ47632654
Lck Inhibits Heat Shock Protein 65-Mediated Reverse Cholesterol Transport in T Cells.Q48300814
Regulatory T cells as a new therapeutic target for atherosclerosis.Q50093330
Immune-inflammatory responses in atherosclerosis: Role of an adaptive immunity mainly driven by T and B cells.Q51719990
Impaired regulatory T-cell response and enhanced atherosclerosis in the absence of inducible costimulatory molecule.Q53591929
Serum amyloid P component therapeutically attenuates atherosclerosis in mice via its effects on macrophages.Q55311460
Inflammation in atherosclerosisQ57295305
Natural regulatory T cells control the development of atherosclerosis in miceQ58149268
Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout miceQ73288555
Lymphocytes in atherosclerosisQ84078750
Heat shock protein 65 promotes atherosclerosis through impairing the properties of high density lipoproteinQ86156924
ZAP70 deficiency promotes reverse cholesterol transport through MAPK/ERK pathway in Jurkat cellQ91030393
P921main subjectcell differentiationQ210861
P304page(s)87-97
P577publication date2020-01-21
P1433published inJournal of Molecular and Cellular CardiologyQ2061932
P1476titleLCK inhibitor attenuates atherosclerosis in ApoE-/- mice via regulating T cell differentiation and reverse cholesterol transport
P478volume139