Platelet chemokines in vascular disease

scientific article published on 21 August 2008

Platelet chemokines in vascular disease is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1161/ATVBAHA.108.169417
P932PMC publication ID2657037
P698PubMed publication ID18723831

P50authorKlaus F. LeyQ89016809
Philipp Von HundelshausenQ43094268
P2093author name stringChristian A Gleissner
P2860cites workThe CXC-chemokine platelet factor 4 promotes monocyte survival and induces monocyte differentiation into macrophagesQ22253155
Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophilsQ24293111
Induction of dendritic cell-like phenotype in macrophages during foam cell formationQ24294246
Platelet-derived stromal cell-derived factor-1 regulates adhesion and promotes differentiation of human CD34+ cells to endothelial progenitor cellsQ80217129
Platelet factor 4 in conjunction with IL-4 directs differentiation of human monocytes into specialized antigen-presenting cellsQ80471129
Platelet factor 4 (CXC chemokine ligand 4) differentially regulates respiratory burst, survival, and cytokine expression of human monocytes by using distinct signaling pathwaysQ80736159
Platelet factor 4 is chemotactic for neutrophils and monocytesQ24302223
An alternatively spliced variant of CXCR3 mediates the inhibition of endothelial cell growth induced by IP-10, Mig, and I-TAC, and acts as functional receptor for platelet factor 4Q24303828
CD40 ligand on activated platelets triggers an inflammatory reaction of endothelial cellsQ24310570
Reduction of atherosclerosis in mice by inhibition of CD40 signallingQ24316540
Platelet factor 4 enhances the binding of oxidized low-density lipoprotein to vascular wall cellsQ24323257
Platelet-derived CXC chemokines: old players in new gamesQ28141629
The CC chemokines MDC and TARC induce platelet activation via CCR4Q28177034
Platelet chemokines and chemokine receptors: linking hemostasis, inflammation, and host defenseQ28186087
Platelet alpha-granule proteins: studies on release and subcellular localizationQ28238444
GRO family chemokines are specialized for monocyte arrest from flowQ28254713
Structural and functional comparison of the genes for human platelet factor 4 and PF4altQ28261701
Occurrence of platelet basic protein, a precursor of low affinity platelet factor 4 and beta-thromboglobulin, in human platelets and megakaryocytesQ28285768
Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injuryQ28286412
Cloning of a full-length cDNA encoding the neutrophil-activating peptide ENA-78 from human plateletsQ28305812
Novel role of the membrane-bound chemokine fractalkine in platelet activation and adhesionQ28578402
Severe reduction in leukocyte adhesion and monocyte extravasation in mice deficient in CC chemokine receptor 2.Q28590391
Inflammation, atherosclerosis, and coronary artery diseaseQ29547232
The pathogenesis of atherosclerosis: a perspective for the 1990sQ29547827
Chemokines: a new classification system and their role in immunityQ29615663
The biology of chemokines and their receptorsQ29619170
Thrombocidins, microbicidal proteins from human blood platelets, are C-terminal deletion products of CXC chemokinesQ29871535
Adenosine diphosphate strongly potentiates the ability of the chemokines MDC, TARC, and SDF-1 to stimulate platelet functionQ30306721
Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.Q30310323
Role of platelets in the development of atherosclerosisQ30312243
Vascular adhesion molecules in atherosclerosisQ30444182
Laminar shear stress-induced GRO mRNA and protein expression in endothelial cellsQ31960227
Platelet chemokines and their receptors: what is their relevance to platelet storage and transfusion practice?Q33341106
Platelet factor 4 is a negative autocrine in vivo regulator of megakaryopoiesis: clinical and therapeutic implicationsQ33375217
Response to injury and atherogenesisQ33494262
MCP-1 deficiency reduces susceptibility to atherosclerosis in mice that overexpress human apolipoprotein B.Q33844451
The beta-thromboglobulins and platelet factor 4: blood platelet-derived CXC chemokines with divergent roles in early neutrophil regulationQ33894356
Megakaryocytes and beyond: the birth of plateletsQ34215516
Up-regulated expression of the CXCR2 ligand KC/GRO-alpha in atherosclerotic lesions plays a central role in macrophage accumulation and lesion progression.Q35088170
Platelets and chemokines in atherosclerosis: partners in crimeQ36085380
Effects of the neutrophil-activating peptide NAP-2, platelet basic protein, connective tissue-activating peptide III and platelet factor 4 on human neutrophilsQ36357015
Platelets as immune cells: bridging inflammation and cardiovascular diseaseQ36699744
CC chemokine ligand-5 (CCL5/RANTES) and CC chemokine ligand-18 (CCL18/PARC) are specific markers of refractory unstable angina pectoris and are transiently raised during severe ischemic symptomsQ40168375
Differential and additive effects of platelet-derived chemokines on monocyte arrest on inflamed endothelium under flow conditionsQ40420958
Role of the platelet in atherogenesisQ40796313
Endothelial expression of E-selectin is induced by the platelet-specific chemokine platelet factor 4 through LRP in an NF-kappaB-dependent mannerQ42742789
Functional expression of CCR1, CCR3, CCR4, and CXCR4 chemokine receptors on human platelets.Q43511392
Effect of CXC chemokine platelet factor 4 on differentiation and function of monocyte-derived dendritic cellsQ44526949
Platelet factor 4 (PF-4)–induced neutrophil adhesion is controlled by src-kinases, whereas PF-4–mediated exocytosis requires the additional activation of p38 MAP kinase and phosphatidylinositol 3-kinaseQ44639015
Platelet factor 4/CXCL4 induces phagocytosis and the generation of reactive oxygen metabolites in mononuclear phagocytes independently of Gi protein activation or intracellular calcium transientsQ44987493
Circulating chemokines accurately identify individuals with clinically significant atherosclerotic heart diseaseQ46745405
Platelet factor 4/CXCL4-stimulated human monocytes induce apoptosis in endothelial cells by the release of oxygen radicalsQ46802145
Mast cells and neutrophils proteolytically activate chemokine precursor CTAP-III and are subject to counterregulation by PF-4 through inhibition of chymase and cathepsin G.Q46827240
Decreased lesion formation in CCR2-/- mice reveals a role for chemokines in the initiation of atherosclerosisQ46897070
Platelets release CXCL4L1, a nonallelic variant of the chemokine platelet factor-4/CXCL4 and potent inhibitor of angiogenesis.Q51606009
CXCL4-induced migration of activated T lymphocytes is mediated by the chemokine receptor CXCR3.Q51792193
Requirement for CD154 in the progression of atherosclerosis.Q52536870
Platelet factor 4 binds to low-density lipoprotein receptors and disrupts the endocytic machinery, resulting in retention of low-density lipoprotein on the cell surface.Q52545982
Expression of HIF-1alpha in injured arteries controls SDF-1alpha mediated neointima formation in apolipoprotein E deficient mice.Q53522261
Platelet microbicidal activity is an important defense factor against viridans streptococcal endocarditis.Q53999657
RANTES deposition by platelets triggers monocyte arrest on inflamed and atherosclerotic endothelium.Q54014329
Heterophilic interactions of platelet factor 4 and RANTES promote monocyte arrest on endotheliumQ57574602
Dynamic Visualization of Thrombopoiesis Within Bone MarrowQ58450371
MCP-1 and IL-8 trigger firm adhesion of monocytes to vascular endothelium under flow conditionsQ59064735
Regulation of endothelial progenitor cell homing after arterial injuryQ61612305
CXCR3-mediated opposite effects of CXCL10 and CXCL4 on T1 or T2 cytokine productionQ61638171
Platelet-derived chemokines in vascular biologyQ63916907
The stromal cell-derived factor-1 chemokine is a potent platelet agonist highly expressed in atherosclerotic plaques.Q64928622
Release of platelet factor 4 in vivo during intravascular coagulation and in thrombotic statesQ68428788
Intra-platelet platelet factor 4 (IP.PF4) and the heparin-mobilisable pool of PF4 in health and atherosclerosisQ70660633
TNF-alpha renders human neutrophils responsive to platelet factor 4. Comparison of PF-4 and IL-8 reveals different activity profiles of the two chemokinesQ70988422
Regulation of adhesion of CD4+ T lymphocytes to intact or heparinase-treated subendothelial extracellular matrix by diffusible or anchored RANTES and MIP-1 betaQ71656917
Neutrophil-activating peptides NAP-2 and IL-8 bind to the same sites on neutrophils but interact in different ways. Discrepancies in binding affinities, receptor densities, and biologic effectsQ72303938
Connective tissue-activating peptide III desensitizes chemokine receptors on neutrophils. Requirement for proteolytic formation of the neutrophil-activating peptide 2Q72879713
The CXC-chemokine neutrophil-activating peptide-2 induces two distinct optima of neutrophil chemotaxis by differential interaction with interleukin-8 receptors CXCR-1 and CXCR-2Q73886945
Human vascular smooth muscle cells express receptors for CC chemokinesQ74351441
Platelet factor 4 inhibits proliferation and cytokine release of activated human T cellsQ74410090
Platelet-derived chemokines CXC chemokine ligand (CXCL)7, connective tissue-activating peptide III, and CXCL4 differentially affect and cross-regulate neutrophil adhesion and transendothelial migrationQ74650583
Activated platelets induce monocyte chemotactic protein-1 secretion and surface expression of intercellular adhesion molecule-1 on endothelial cellsQ77319716
Absence of CC chemokine receptor-2 reduces atherosclerosis in apolipoprotein E-deficient miceQ77340592
Characterization of a neutrophil cell surface glycosaminoglycan that mediates binding of platelet factor 4Q77353640
Inhibition of in vitro angiogenesis by platelet factor-4-derived peptides and mechanism of actionQ78039757
Activated platelets trigger an inflammatory response and enhance migration of aortic smooth muscle cellsQ79086335
Platelet factor 4 localization in carotid atherosclerotic plaques: correlation with clinical parametersQ79339926
Elimination of platelet factor 4 (PF4) from platelets reduces atherosclerosis in C57Bl/6 and apoE-/- miceQ79828506
Genetic control of chemokines in severe human internal carotid artery stenosisQ80149834
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)1920-1927
P577publication date2008-08-21
P1433published inArteriosclerosis, Thrombosis, and Vascular BiologyQ4797542
P1476titlePlatelet chemokines in vascular disease
P478volume28

Reverse relations

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