| scholarly article | Q13442814 |
| P356 | DOI | 10.1126/SCIENCE.2244210 |
| P698 | PubMed publication ID | 2244210 |
| P50 | author | Joseph L. Goldstein | Q271424 |
| P2093 | author name string | M S Brown | |
| S Ishibashi | |||
| R E Hammer | |||
| M Yokode | |||
| P2860 | cites work | A simple method for the isolation and purification of total lipides from animal tissues | Q25939009 |
| The LDL receptor gene: a mosaic of exons shared with different proteins | Q26269835 | ||
| Regulation of the mevalonate pathway | Q29547763 | ||
| A receptor-mediated pathway for cholesterol homeostasis | Q29616158 | ||
| Expression of apolipoprotein B mRNAs encoding higher- and lower-molecular weight isoproteins in rat liver and intestine | Q33831336 | ||
| Overexpression of low density lipoprotein (LDL) receptor eliminates LDL from plasma in transgenic mice | Q34175241 | ||
| Dependence of metabolic and structural heterogeneity of cholesterol ester-rich very low density lipoproteins on the duration of cholesterol feeding in rabbits | Q34559811 | ||
| Saturation and suppression of hepatic lipoprotein receptors: a mechanism for the hypercholesterolemia of cholesterol-fed rabbits | Q35319170 | ||
| Tissue-specific sorting of the human LDL receptor in polarized epithelia of transgenic mice | Q36223333 | ||
| Introns increase transcriptional efficiency in transgenic mice | Q37486009 | ||
| Factors affecting the efficiency of introducing foreign DNA into mice by microinjecting eggs | Q37545665 | ||
| Dietary saturated triacylglycerols suppress hepatic low density lipoprotein receptor activity in the hamster | Q37546278 | ||
| Regulation of cholesterol metabolism. I. | Q40013829 | ||
| Atherogenesis: a postprandial phenomenon | Q40237350 | ||
| Metabolism of canine beta-very low density lipoproteins in normal and cholesterol-fed dogs | Q46438724 | ||
| A sensitive enzymatic method for determination of free and esterified tissue cholesterol | Q67653003 | ||
| Variation in susceptibility to atherosclerosis among inbred strains of mice | Q69805944 | ||
| 19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells | Q70193016 | ||
| Myocardial infarction in rats fed diets containing high fat, cholesterol, thiouracil, and sodium cholate | Q78509260 | ||
| P433 | issue | 4985 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | hypercholesterolemia | Q762713 |
| overexpression | Q61643320 | ||
| P304 | page(s) | 1273-1275 | |
| P577 | publication date | 1990-11-01 | |
| P1433 | published in | Science | Q192864 |
| P1476 | title | Diet-induced hypercholesterolemia in mice: prevention by overexpression of LDL receptors | |
| P478 | volume | 250 |
| Q35796491 | A dose-response study of the effects of dietary cholesterol on fasting and postprandial lipid and lipoprotein metabolism in healthy young men. |
| Q24646308 | A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism |
| Q35148589 | Activating Signal Cointegrator 2 Required for Liver Lipid Metabolism Mediated by Liver X Receptors in Mice |
| Q40554926 | Advances in molecular biology: implications for the future of clinical nutrition practice |
| Q44734042 | Ameliorative effects of resveratrol on liver injury in streptozotocin-induced diabetic rats. |
| Q35880164 | Analysis of HSD3B7 knockout mice reveals that a 3alpha-hydroxyl stereochemistry is required for bile acid function |
| Q34497951 | Apolipoprotein E: from lipid transport to neurobiology |
| Q46953909 | Atherogenesis in transgenic mice expressing human apolipoprotein(a) |
| Q50949153 | Attenuating effect of clock mutation on triglyceride contents in the ICR mouse liver under a high-fat diet. |
| Q36449465 | Bio F1B hamster: a unique animal model with reduced lipoprotein lipase activity to investigate nutrient mediated regulation of lipoprotein metabolism |
| Q37388151 | Blunted feedback suppression of SREBP processing by dietary cholesterol in transgenic mice expressing sterol-resistant SCAP(D443N). |
| Q33435708 | Carboxy-terminal deletion of the HDL receptor reduces receptor levels in liver and steroidogenic tissues, induces hypercholesterolemia, and causes fatal heart disease |
| Q71245678 | Changes in plasma lipoprotein cholesterol levels by antisense oligodeoxynucleotides against cholesteryl ester transfer protein in cholesterol-fed rabbits |
| Q28273937 | Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha |
| Q36806480 | Cholesterol feeding reduces nuclear forms of sterol regulatory element binding proteins in hamster liver |
| Q38323357 | Chronic intermittent hypoxia upregulates genes of lipid biosynthesis in obese mice |
| Q46923059 | Clock mutation facilitates accumulation of cholesterol in the liver of mice fed a cholesterol and/or cholic acid diet |
| Q41860989 | Coronary atherosclerosis in transplanted mouse hearts. I. Time course and immunogenetic and immunopathological considerations. |
| Q46784041 | Cross-talk between thyroid hormone receptor and liver X receptor regulatory pathways is revealed in a thyroid hormone resistance mouse model |
| Q93009314 | Curcumin attenuates insulin resistance and hepatic lipid accumulation in a rat model of intra-uterine growth restriction through insulin signalling pathway and sterol regulatory element binding proteins |
| Q28508851 | Deficiency of carbohydrate response element-binding protein (ChREBP) reduces lipogenesis as well as glycolysis |
| Q43109611 | Developmental programming of sex-dependent alterations in lipid metabolism: a role for long-term, sex-specific alterations in LDL-receptor expression. Focus on "developmental programming of lipid metabolism and aortic vascular function in C57BL/6 mi |
| Q36658372 | Diabetic atherosclerosis in APOE*4 mice: synergy between lipoprotein metabolism and vascular inflammation |
| Q28547562 | Dietary Tributyrin Supplementation Attenuates Insulin Resistance and Abnormal Lipid Metabolism in Suckling Piglets with Intrauterine Growth Retardation |
| Q44307873 | Dietary rhubarb (Rheum rhaponticum) stalk fibre does not lower plasma cholesterol levels in diabetic rats |
| Q35250984 | Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia |
| Q33849024 | Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL |
| Q91817578 | Effect of Curcumin on Growth Performance, Inflammation, Insulin level, and Lipid Metabolism in Weaned Piglets with IUGR |
| Q37164869 | Effect of chronic ethanol exposure on the liver of Clock-mutant mice |
| Q40905171 | Exploring pathogenetic mechanisms using transgenic animals |
| Q43224118 | Fibroblast growth factor 21 reverses hepatic steatosis, increases energy expenditure, and improves insulin sensitivity in diet-induced obese mice |
| Q51759803 | Fish oil induced hyperlipidemia and oxidative stress in BioF1B hamsters is attenuated by elderberry extract. |
| Q35205250 | From diet to DNA: dietary patterning of gene expression |
| Q35232748 | Gene-environment interactions in atherosclerosis |
| Q54575442 | Hepatic lipid accumulation in apolipoprotein C-I-deficient mice is potentiated by cholesteryl ester transfer protein. |
| Q36197688 | High density lipoprotein metabolism in low density lipoprotein receptor-deficient mice |
| Q42327899 | Human LDL receptor enhances sequestration of ApoE4 and VLDL remnants on the surface of hepatocytes but not their internalization in mice |
| Q29615235 | Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery |
| Q44789735 | Hyperlipidaemic effect of fish oil in Bio F1B hamsters |
| Q38297185 | Increased expression of the sterol regulatory element-binding protein-1 gene in insulin receptor substrate-2(-/-) mouse liver |
| Q29012150 | Increased oxidative stress in obesity and its impact on metabolic syndrome |
| Q35210714 | Insulin resistance and diabetes mellitus in transgenic mice expressing nuclear SREBP-1c in adipose tissue: model for congenital generalized lipodystrophy |
| Q36212658 | Knockout of the abetalipoproteinemia gene in mice: reduced lipoprotein secretion in heterozygotes and embryonic lethality in homozygotes. |
| Q24563247 | Knockout of the mouse apolipoprotein B gene results in embryonic lethality in homozygotes and protection against diet-induced hypercholesterolemia in heterozygotes |
| Q34258604 | Koch's postulates for cholesterol |
| Q46655155 | Lack of stimulation of cholesteryl ester transfer protein by cholesterol in the presence of a high-fat diet |
| Q52895402 | Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy. |
| Q33410814 | Lipid profile and serum characteristics of the blind subterranean mole rat, Spalax |
| Q40588222 | Lipoproteins and their functions |
| Q36044159 | Liver, lipoproteins and disease: I. Biochemistry of lipoprotein metabolism |
| Q41063915 | Liver-directed gene transfer and application to therapy |
| Q41611337 | Lower plasma levels and accelerated clearance of high density lipoprotein (HDL) and non-HDL cholesterol in scavenger receptor class B type I transgenic mice |
| Q33639405 | Mammary gland expression of mouse mammary tumor virus is regulated by a novel element in the long terminal repeat. |
| Q36508476 | Maternal diet rich in saturated fats has deleterious effects on plasma lipids of mice |
| Q36957202 | Mesolimbic neuropeptide W coordinates stress responses under novel environments |
| Q58136301 | Molecular genetics of familial hypercholesterolaemia: common and rare mutations of the low density lipoprotein receptor gene |
| Q37379533 | Noninvasive quantification of pancreatic fat in humans |
| Q28204028 | Normal Sorting but Defective Endocytosis of the Low Density Lipoprotein Receptor in Mice with Autosomal Recessive Hypercholesterolemia |
| Q34643522 | Other ways to skin a cat: activating SREBP without Scap |
| Q24631468 | Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis |
| Q36857781 | Overexpression of apolipoprotein E in transgenic mice: marked reduction in plasma lipoproteins except high density lipoprotein and resistance against diet-induced hypercholesterolemia |
| Q73409190 | Overexpression of low density lipoprotein receptor eliminates apolipoprotein B100-containing lipoproteins from circulation and markedly prevents early atherogenesis in apolipoprotein E-deficient mice |
| Q30274556 | Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance |
| Q45881945 | Overexpression of the HDL receptor SR-BI alters plasma HDL and bile cholesterol levels |
| Q37360326 | Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a |
| Q46806178 | Phospholipid transfer protein deficiency ameliorates diet-induced hypercholesterolemia and inflammation in mice |
| Q42915118 | Plasma and liver lipid profiles in rats exposed to chronic hypobaric hypoxia: changes in metabolic pathways |
| Q41021318 | Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E. Accelerated clearance of lipoproteins containing apolipoprotein B. |
| Q38336252 | Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver. |
| Q79712804 | Quantitative effects of common genetic variations in the 3'UTR of the human LDL-receptor gene and their associations with plasma lipid levels in the Atherosclerosis Risk in Communities study |
| Q44317088 | Quantitative trait loci that determine lipoprotein cholesterol levels in DBA/2J and CAST/Ei inbred mice |
| Q36434617 | Recent developments in the treatment of atherosclerosis |
| Q24316540 | Reduction of atherosclerosis in mice by inhibition of CD40 signalling |
| Q71952848 | Reduction of serum cholesterol in Watanabe rabbits by xenogeneic hepatocellular transplantation |
| Q71858771 | Regulation of apolipoprotein B secretion in hepatocytes from Watanabe heritable hyperlipidemic rabbit, an animal model for familial hypercholesterolemia |
| Q41728631 | Relationship between expression levels and atherogenesis in scavenger receptor class B, type I transgenics |
| Q41464544 | Response to dietary fat and cholesterol and genetic polymorphisms |
| Q42992915 | Reversal of hyperlipidaemia in apolipoprotein C1 transgenic mice by adenovirus-mediated gene delivery of the low-density-lipoprotein receptor, but not by the very-low-density-lipoprotein receptor |
| Q24290548 | Role of LXRs in control of lipogenesis |
| Q28365331 | SREBP cleavage-activating protein (SCAP) is required for increased lipid synthesis in liver induced by cholesterol deprivation and insulin elevation |
| Q39610333 | Scavenger receptor CD36 mediates uptake of high density lipoproteins in mice and by cultured cells |
| Q28646399 | Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes |
| Q71563616 | Tamoxifen elevates transforming growth factor-beta and suppresses diet-induced formation of lipid lesions in mouse aorta |
| Q35604030 | The familial hypercholesterolemia (FH)-North Karelia mutation of the low density lipoprotein receptor gene deletes seven nucleotides of exon 6 and is a common cause of FH in Finland |
| Q48222568 | The low density lipoprotein receptor in Xenopus laevis. II. Feedback repression mediated by conserved sterol regulatory element |
| Q35233650 | The two-receptor model of lipoprotein clearance: tests of the hypothesis in "knockout" mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins |
| Q36315905 | Tissue- and nuclear receptor-specific function of the C-terminal LXXLL motif of coactivator NCoA6/AIB3 in mice |
| Q36525382 | Transgenic mouse models of lipoprotein metabolism and atherosclerosis |
| Q31582971 | Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells |
| Q38344355 | p53 involvement in the pathogenesis of fatty liver disease. |
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