scholarly article | Q13442814 |
P50 | author | Helen Hobbs | Q21433424 |
Jonathan C. Cohen | Q24063837 | ||
P2093 | author name string | Wei-Ping Li | |
Joachim Herz | |||
Robert E. Hammer | |||
Christopher Jones | |||
P2860 | cites work | Reeler/Disabled-like disruption of neuronal migration in knockout mice lacking the VLDL receptor and ApoE receptor 2 | Q22010158 |
Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction | Q22254170 | ||
Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor | Q24297663 | ||
Domain map of the LDL receptor: Sequence homology with the epidermal growth factor precursor | Q24301384 | ||
The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor | Q24304115 | ||
ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2 | Q24306476 | ||
Molecular mechanisms of autosomal recessive hypercholesterolemia | Q24315900 | ||
The autosomal recessive hypercholesterolemia (ARH) protein interfaces directly with the clathrin-coat machinery | Q24321718 | ||
Dual roles for the Dab2 adaptor protein in embryonic development and kidney transport | Q24536278 | ||
Inducible inactivation of hepatic LRP gene by cre-mediated recombination confirms role of LRP in clearance of chylomicron remnants | Q24564846 | ||
Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein | Q28186061 | ||
Autosomal recessive hypercholesterolaemia in Sardinia, Italy, and mutations in ARH: a clinical and molecular genetic analysis | Q28207619 | ||
Differential functions of members of the low density lipoprotein receptor family suggested by their distinct endocytosis rates | Q28209002 | ||
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P433 | issue | 31 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | biochemistry | Q7094 |
cell biology | Q7141 | ||
lipoprotein | Q28350 | ||
Low density lipoprotein receptor | Q14872730 | ||
Early endosome antigen 1 | Q14911544 | ||
hypercholesterolemia | Q762713 | ||
signal transducing adaptor protein | Q5964993 | ||
endocytosis | Q189814 | ||
Low density lipoprotein receptor adaptor protein 1 | Q21496937 | ||
autosomal recessive hypercholesterolemia | Q30988959 | ||
P304 | page(s) | 29024-30 | |
P577 | publication date | 2003-05-13 | |
2003-08-01 | |||
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia | |
Normal Sorting but Defective Endocytosis of the Low Density Lipoprotein Receptor in Mice with Autosomal Recessive Hypercholesterolemia | |||
P478 | volume | 278 |
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Q36992932 | ARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression |
Q28269595 | Adaptor protein ARH is recruited to the plasma membrane by low density lipoprotein (LDL) binding and modulates endocytosis of the LDL/LDL receptor complex in hepatocytes |
Q44919494 | Apolipoprotein E receptors are required for reelin-induced proteasomal degradation of the neuronal adaptor protein Disabled-1. |
Q43104582 | Atherogenic remnant lipoproteins: role for proteoglycans in trapping, transferring, and internalizing |
Q27678570 | Atomic structure of the autosomal recessive hypercholesterolemia phosphotyrosine-binding domain in complex with the LDL-receptor tail |
Q28975614 | CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL |
Q33751689 | Cargo- and adaptor-specific mechanisms regulate clathrin-mediated endocytosis. |
Q34591249 | Casein kinase 2 phosphorylation of protein kinase C and casein kinase 2 substrate in neurons (PACSIN) 1 protein regulates neuronal spine formation |
Q24338638 | Characterization of the adaptor protein ARH expression in the brain and ARH molecular interactions |
Q33705255 | Cholesterol pathways affected by small molecules that decrease sterol levels in Niemann-Pick type C mutant cells |
Q28588292 | Decreased plasma cholesterol and hypersensitivity to statins in mice lacking Pcsk9 |
Q28505513 | Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways |
Q35250984 | Disruption of LDL but not VLDL clearance in autosomal recessive hypercholesterolemia |
Q42660727 | Dissection of the endogenous cellular pathways of PCSK9-induced low density lipoprotein receptor degradation: evidence for an intracellular route |
Q36843299 | Endocytic adaptors Arh and Dab2 control homeostasis of circulatory cholesterol |
Q28076375 | Endocytosis and Physiology: Insights from Disabled-2 Deficient Mice |
Q45952956 | Gene expression profiles during human CD4+ T cell differentiation. |
Q57825461 | Genetic Markers for Coronary Artery Disease |
Q34594058 | Giardia lamblia low-density lipoprotein receptor-related protein is involved in selective lipoprotein endocytosis and parasite replication. |
Q42112172 | Identification of a VLDL-induced, FDNPVY-independent internalization mechanism for the LDLR. |
Q38329786 | Identification of novel and known oocyte-specific genes using complementary DNA subtraction and microarray analysis in three different species |
Q38713991 | Induction of MiR133a expression by IL-19 targets LDLRAP1 and reduces oxLDL uptake in VSMC. |
Q39051108 | Internalized PCSK9 dissociates from recycling LDL receptors in PCSK9-resistant SV-589 fibroblasts |
Q24608930 | Low-density lipoprotein receptor (LDLR) family orchestrates cholesterol homeostasis |
Q28260962 | Low-density lipoprotein receptor-related protein interacts with MafB, a regulator of hindbrain development |
Q35711232 | Pathway-Wide Association Study Implicates Multiple Sterol Transport and Metabolism Genes in HDL Cholesterol Regulation. |
Q38336252 | Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver. |
Q34620344 | Processing of Reelin by embryonic neurons is important for function in tissue but not in dissociated cultured neurons. |
Q27009477 | Proprotein convertase subtilisin/kexin type 9: from the discovery to the development of new therapies for cardiovascular diseases |
Q36744120 | Quantitative fluorescence imaging reveals point of release for lipoproteins during LDLR-dependent uptake |
Q39263076 | Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB. |
Q36822549 | S-nitrosylation of ARH is required for LDL uptake by the LDL receptor |
Q57057017 | Science, serendipity, and the single degree |
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Q35569243 | Sorting it out: AP-2 and alternate clathrin adaptors in endocytic cargo selection |
Q37403077 | The ARH adaptor protein regulates endocytosis of the ROMK potassium secretory channel in mouse kidney |
Q34580436 | The clathrin adaptor proteins ARH, Dab2, and numb play distinct roles in Niemann-Pick C1-Like 1 versus low density lipoprotein receptor-mediated cholesterol uptake. |
Q30482500 | The endocytic adaptor protein ARH associates with motor and centrosomal proteins and is involved in centrosome assembly and cytokinesis. |
Q28472536 | The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice |
Q24294525 | The modular adaptor protein ARH is required for low density lipoprotein (LDL) binding and internalization but not for LDL receptor clustering in coated pits |
Q40369997 | The modular adaptor protein autosomal recessive hypercholesterolemia (ARH) promotes low density lipoprotein receptor clustering into clathrin-coated pits |
Q30481717 | The thyromimetic T-0681 protects from atherosclerosis. |
Q44565939 | Xenopus autosomal recessive hypercholesterolemia protein couples lipoprotein receptors with the AP-2 complex in oocytes and embryos and is required for vitellogenesis |