scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M208539200 |
P8608 | Fatcat ID | release_ri3is52spba63emz6wmggptd7m |
P3181 | OpenCitations bibliographic resource ID | 3907421 |
P698 | PubMed publication ID | 12221107 |
P5875 | ResearchGate publication ID | 11168591 |
P50 | author | Helen Hobbs | Q21433424 |
Jonathan C. Cohen | Q24063837 | ||
P2093 | author name string | Ming Yi | |
Guocheng He | |||
Peter Michaely | |||
Sarita Gupta | |||
P2860 | cites work | The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites | Q24301593 |
Sequence-specific recognition of the internalization motif of the Alzheimer's amyloid precursor protein by the X11 PTB domain | Q24536014 | ||
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Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase | Q28131695 | ||
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Autosomal recessive hypercholesterolemia caused by mutations in a putative LDL receptor adaptor protein | Q28186061 | ||
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Clathrin-binding proteins: got a motif? Join the network! | Q34328624 | ||
Dockers at the crossroads | Q34465504 | ||
Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and beta-arrestin proteins | Q34568617 | ||
Clathrin adaptors really adapt | Q34709976 | ||
Tissue-specific sorting of the human LDL receptor in polarized epithelia of transgenic mice | Q36223333 | ||
The LDL receptor clustering motif interacts with the clathrin terminal domain in a reverse turn conformation | Q36256170 | ||
Hepatocytic lipoprotein receptors and intracellular lipoprotein catabolism | Q39289456 | ||
The NPXY internalization signal of the LDL receptor adopts a reverse-turn conformation | Q67802007 | ||
Characterization of a new form of inherited hypercholesterolemia: familial recessive hypercholesterolemia | Q74598521 | ||
P433 | issue | 46 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Low density lipoprotein receptor adaptor protein 1 | Q6693000 |
low-density lipoprotein particle receptor binding | Q14890332 | ||
AP-2 adaptor complex binding | Q21106401 | ||
Low density lipoprotein receptor adaptor protein 1 | Q21496937 | ||
P304 | page(s) | 44044-9 | |
P577 | publication date | 2002-11-15 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2 | |
P478 | volume | 277 |
Q34432614 | A clathrin coat assembly role for the muniscin protein central linker revealed by TALEN-mediated gene editing. |
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Q33792902 | A phosphotyrosine switch for cargo sequestration at clathrin-coated buds |
Q30478248 | A single common portal for clathrin-mediated endocytosis of distinct cargo governed by cargo-selective adaptors |
Q24296494 | AMN directs endocytosis of the intrinsic factor-vitamin B(12) receptor cubam by engaging ARH or Dab2 |
Q30430390 | ARH cooperates with AP-1B in the exocytosis of LDLR in polarized epithelial cells |
Q36992932 | ARH directs megalin to the endocytic recycling compartment to regulate its proteolysis and gene expression |
Q28269595 | Adaptor protein ARH is recruited to the plasma membrane by low density lipoprotein (LDL) binding and modulates endocytosis of the LDL/LDL receptor complex in hepatocytes |
Q33638980 | Advances in dyslipidemia management for prevention of atherosclerosis: PCSK9 monoclonal antibody therapy and beyond |
Q35883857 | Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other |
Q28155799 | Assembly of Cell Regulatory Systems Through Protein Interaction Domains |
Q28564763 | Association of the low-density lipoprotein receptor with caveolae in hamster and rat liver |
Q43104582 | Atherogenic remnant lipoproteins: role for proteoglycans in trapping, transferring, and internalizing |
Q27678570 | Atomic structure of the autosomal recessive hypercholesterolemia phosphotyrosine-binding domain in complex with the LDL-receptor tail |
Q45107252 | Autosomal recessive hypercholesterolaemia: normalization of plasma LDL cholesterol by ezetimibe in combination with statin treatment |
Q24305128 | Autosomal recessive hypercholesterolemia protein interacts with and regulates the cell surface level of Alzheimer's amyloid beta precursor protein |
Q30417272 | BRAG2/GEP100/IQSec1 interacts with clathrin and regulates α5β1 integrin endocytosis through activation of ADP ribosylation factor 5 (Arf5). |
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Q33435708 | Carboxy-terminal deletion of the HDL receptor reduces receptor levels in liver and steroidogenic tissues, induces hypercholesterolemia, and causes fatal heart disease |
Q34382206 | Cargo recognition in clathrin-mediated endocytosis |
Q33751689 | Cargo- and adaptor-specific mechanisms regulate clathrin-mediated endocytosis. |
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Q24296418 | Functional dissection of an AP-2 beta2 appendage-binding sequence within the autosomal recessive hypercholesterolemia protein |
Q37362304 | Functional roles of short sequence motifs in the endocytosis of membrane receptors |
Q33564499 | Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain. |
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Q42112172 | Identification of a VLDL-induced, FDNPVY-independent internalization mechanism for the LDLR. |
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Q35938094 | LDL-receptor mutations in Europe |
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Q28258969 | Lipoprotein(a) catabolism is regulated by proprotein convertase subtilisin/kexin type 9 through the low density lipoprotein receptor |
Q40542671 | Macrophage colony-stimulating factor differentially regulates low density lipoprotein and transferrin receptors. |
Q36075377 | MicroRNA-27a decreases the level and efficiency of the LDL receptor and contributes to the dysregulation of cholesterol homeostasis |
Q36145238 | Molecular characterization of proprotein convertase subtilisin/kexin type 9-mediated degradation of the LDLR. |
Q37972887 | Molecular pathology of familial hypercholesterolemia, related dyslipidemias and therapies beyond the statins |
Q24672834 | Monogenic hypercholesterolemia: new insights in pathogenesis and treatment |
Q35581908 | New Light on a Long‐Known Protein Family |
Q28204028 | Normal Sorting but Defective Endocytosis of the Low Density Lipoprotein Receptor in Mice with Autosomal Recessive Hypercholesterolemia |
Q27641195 | Origins of peptide selectivity and phosphoinositide binding revealed by structures of disabled-1 PTB domain complexes |
Q24310854 | PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2 |
Q38921625 | Pathways of protein and lipid receptor-mediated transcytosis in drug delivery. |
Q38336252 | Post-transcriptional regulation of low density lipoprotein receptor protein by proprotein convertase subtilisin/kexin type 9a in mouse liver. |
Q94466073 | Potential Link Between Proprotein Convertase Subtilisin/Kexin Type 9 and Alzheimer's Disease |
Q34723257 | Proprotein convertase subtilisin/kexin type 9 (PCSK9) can mediate degradation of the low density lipoprotein receptor-related protein 1 (LRP-1) |
Q27009477 | Proprotein convertase subtilisin/kexin type 9: from the discovery to the development of new therapies for cardiovascular diseases |
Q33796356 | Reciprocal regulation of endocytosis and metabolism |
Q24302853 | Recognition of dileucine-based sorting signals from HIV-1 Nef and LIMP-II by the AP-1 gamma-sigma1 and AP-3 delta-sigma3 hemicomplexes |
Q39263076 | Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB. |
Q24323051 | Restoration of LDL receptor function in cells from patients with autosomal recessive hypercholesterolemia by retroviral expression of ARH1 |
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Q33767978 | Role of the adaptor protein PDZK1 in controlling the HDL receptor SR-BI |
Q36822549 | S-nitrosylation of ARH is required for LDL uptake by the LDL receptor |
Q24311328 | Secreted PCSK9 decreases the number of LDL receptors in hepatocytes and in livers of parabiotic mice |
Q34381865 | Small peptide recognition sequence for intracellular sorting |
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Q36714128 | The cytosolic adaptor AP-1A is essential for the trafficking and function of Niemann-Pick type C proteins |
Q30482500 | The endocytic adaptor protein ARH associates with motor and centrosomal proteins and is involved in centrosome assembly and cytokinesis. |
Q39160284 | The endocytic receptor megalin and its associated proteins in proximal tubule epithelial cells |
Q42749068 | The epidermal growth factor homology domain of the LDL receptor drives lipoprotein release through an allosteric mechanism involving H190, H562, and H586. |
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Q40369997 | The modular adaptor protein autosomal recessive hypercholesterolemia (ARH) promotes low density lipoprotein receptor clustering into clathrin-coated pits |
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Q44565939 | Xenopus autosomal recessive hypercholesterolemia protein couples lipoprotein receptors with the AP-2 complex in oocytes and embryos and is required for vitellogenesis |
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