| scholarly article | Q13442814 |
| P2093 | author name string | Peter Michaely | |
| Zhenze Zhao | |||
| P2860 | cites work | The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA | Q24300736 |
| The adaptor protein Dab2 sorts LDL receptors into coated pits independently of AP-2 and ARH | Q24303966 | ||
| ARH is a modular adaptor protein that interacts with the LDL receptor, clathrin, and AP-2 | Q24306476 | ||
| The autosomal recessive hypercholesterolemia (ARH) protein interfaces directly with the clathrin-coat machinery | Q24321718 | ||
| Three-dimensional structure of a cysteine-rich repeat from the low-density lipoprotein receptor | Q24563806 | ||
| Familial hypercholesterolemia: defective binding of lipoproteins to cultured fibroblasts associated with impaired regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity | Q24621801 | ||
| Transforming growth factor beta-induced phosphorylation of Smad3 is required for growth inhibition and transcriptional induction in epithelial cells | Q24656526 | ||
| Solution structure of the sixth LDL-A module of the LDL receptor | Q27621667 | ||
| Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair | Q27632019 | ||
| Structure of the LDL receptor extracellular domain at endosomal pH | Q27640067 | ||
| Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module | Q27742097 | ||
| Molecular genetics of the LDL receptor gene in familial hypercholesterolemia | Q28207758 | ||
| NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor | Q28254985 | ||
| Adaptor protein ARH is recruited to the plasma membrane by low density lipoprotein (LDL) binding and modulates endocytosis of the LDL/LDL receptor complex in hepatocytes | Q28269595 | ||
| Endocytic recycling | Q29547737 | ||
| A receptor-mediated pathway for cholesterol homeostasis | Q29616158 | ||
| Human apolipoprotein B: structure of carboxyl-terminal domains, sites of gene expression, and chromosomal localization | Q30403358 | ||
| A single common portal for clathrin-mediated endocytosis of distinct cargo governed by cargo-selective adaptors | Q30478248 | ||
| Role of the coated endocytic vesicle in the uptake of receptor-bound low density lipoprotein in human fibroblasts | Q33396990 | ||
| Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region | Q34180927 | ||
| Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain | Q34195375 | ||
| The J.D. mutation in familial hypercholesterolemia: amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors | Q34196707 | ||
| Regulation of plasma cholesterol by lipoprotein receptors | Q34252363 | ||
| The LDL receptor: how acid pulls the trigger | Q36160311 | ||
| Endocytosed beta-VLDL and LDL are delivered to different intracellular vesicles in mouse peritoneal macrophages | Q36223747 | ||
| The influence of particle size and multiple apoprotein E-receptor interactions on the endocytic targeting of beta-VLDL in mouse peritoneal macrophages | Q36530582 | ||
| Dissociation among in vitro telomerase activity, telomere maintenance, and cellular immortalization | Q36754020 | ||
| Familial dysbetalipoproteinemia. Abnormal binding of mutant apoprotein E to low density lipoprotein receptors of human fibroblasts and membranes from liver and adrenal of rats, rabbits, and cows | Q37004383 | ||
| Rate and equilibrium constants for binding of apo-E HDL c (a cholesterol-induced lipoprotein) and low density lipoproteins to human fibroblasts: Evidence for multiple receptor binding of apo-E HDL c | Q37330623 | ||
| Mutational analysis of the ligand binding domain of the low density lipoprotein receptor | Q38346504 | ||
| Regulation of ApoB secretion by the low density lipoprotein receptor requires exit from the endoplasmic reticulum and interaction with ApoE or ApoB. | Q39263076 | ||
| Interaction of canine and swine lipoproteins with the low density lipoprotein receptor of fibroblasts as correlated with heparin/manganese precipitability | Q40073241 | ||
| Inhibition of lipoprotein binding to cell surface receptors of fibroblasts following selective modification of arginyl residues in arginine-rich and B apoproteins | Q40099596 | ||
| Role of lysine residues of plasma lipoproteins in high affinity binding to cell surface receptors on human fibroblasts | Q40189841 | ||
| Absence of cancer-associated changes in human fibroblasts immortalized with telomerase | Q40978424 | ||
| Inefficient degradation of triglyceride-rich lipoprotein by HepG2 cells is due to a retarded transport to the lysosomal compartment | Q41509026 | ||
| Hypertonic media inhibit receptor-mediated endocytosis by blocking clathrin-coated pit formation | Q41570746 | ||
| Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteins | Q41757752 | ||
| Identification of a VLDL-induced, FDNPVY-independent internalization mechanism for the LDLR. | Q42112172 | ||
| Familial hypercholesterolemia in China. Identification of mutations in the LDL-receptor gene that result in a receptor-negative phenotype. | Q43530662 | ||
| A two-module region of the low-density lipoprotein receptor sufficient for formation of complexes with apolipoprotein E ligands | Q44742662 | ||
| Apolipoprotein E-low density lipoprotein receptor binding: study of protein-protein interaction in rationally selected docked complexes | Q44898266 | ||
| Cooperation between fixed and low pH-inducible interfaces controls lipoprotein release by the LDL receptor | Q45114944 | ||
| Scrambled isomers as key intermediates in the oxidative folding of ligand binding module 5 of the low density lipoprotein receptor | Q46699385 | ||
| Sequence, structure, receptor-binding domains and internal repeats of human apolipoprotein B-100 | Q59061800 | ||
| ApoE is necessary and sufficient for the binding of large triglyceride-rich lipoproteins to the LDL receptor; apoB is unnecessary | Q70032566 | ||
| The receptor-binding domain of human apolipoprotein E. Monoclonal antibody inhibition of binding | Q70169933 | ||
| 19 Receptor-mediated endocytosis of low-density lipoprotein in cultured cells | Q70193016 | ||
| Cholesteryl ester accumulation in macrophages resulting from receptor-mediated uptake and degradation of hypercholesterolemic canine beta-very low density lipoproteins | Q71133222 | ||
| Protein folding and calcium binding defects arising from familial hypercholesterolemia mutations of the LDL receptor | Q71477938 | ||
| Recycling of cell-surface receptors: observations from the LDL receptor system | Q72939687 | ||
| Intracellular trafficking of pigeon beta-very low density lipoprotein and low density lipoprotein at low and high concentrations in pigeon macrophages | Q73145548 | ||
| A novel LDLR mutation, H190Y, in a Utah kindred with familial hypercholesterolemia | Q73203387 | ||
| Structure of an LDLR-RAP complex reveals a general mode for ligand recognition by lipoprotein receptors | Q83186563 | ||
| P433 | issue | 39 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | lipoprotein | Q28350 |
| P304 | page(s) | 26528-26537 | |
| P577 | publication date | 2008-08-03 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | The epidermal growth factor homology domain of the LDL receptor drives lipoprotein release through an allosteric mechanism involving H190, H562, and H586. | |
| P478 | volume | 283 |
| Q34497951 | Apolipoprotein E: From lipid transport to neurobiology |
| Q29347262 | Cavin-3 dictates the balance between ERK and Akt signaling |
| Q39867045 | Domain swapping reveals that low density lipoprotein (LDL) type A repeat order affects ligand binding to the LDL receptor |
| Q38601708 | Exploring the complete mutational space of the LDL receptor LA5 domain using molecular dynamics: linking SNPs with disease phenotypes in familial hypercholesterolemia |
| Q38728542 | Identification of roles for H264, H306, H439, and H635 in acid-dependent lipoprotein release by the LDL receptor. |
| Q24321832 | LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeat |
| Q41863567 | Low pH-triggered beta-propeller switch of the low-density lipoprotein receptor assists rhinovirus infection |
| Q58023052 | Low-density lipoprotein receptor is a calcium/magnesium sensor - role of LR4 and LR5 ion interaction kinetics in low-density lipoprotein release in the endosome |
| Q41833733 | Mechanism of LDL binding and release probed by structure-based mutagenesis of the LDL receptor |
| Q24297165 | Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH |
| Q33560560 | Model of human low-density lipoprotein and bound receptor based on cryoEM |
| Q89518507 | Mutation type classification and pathogenicity assignment of sixteen missense variants located in the EGF-precursor homology domain of the LDLR |
| Q36744120 | Quantitative fluorescence imaging reveals point of release for lipoproteins during LDLR-dependent uptake |
| Q37257505 | Receptor-associated protein (RAP) has two high-affinity binding sites for the low-density lipoprotein receptor-related protein (LRP): consequences for the chaperone functions of RAP. |
| Q34975192 | Role of an intramolecular contact on lipoprotein uptake by the LDL receptor |
| Q36822549 | S-nitrosylation of ARH is required for LDL uptake by the LDL receptor |
| Q39205380 | Structural changes induced by acidic pH in human apolipoprotein B-100. |
| Q37002668 | The LXR-IDOL axis defines a clathrin-, caveolae-, and dynamin-independent endocytic route for LDLR internalization and lysosomal degradation |
| Q28115354 | The closed conformation of the LDL receptor is destabilized by the low Ca(++) concentration but favored by the high Mg(++) concentration in the endosome |
| Q37357958 | The role of calcium in lipoprotein release by the low-density lipoprotein receptor |
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