The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA (scientific article)

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Q41661872	Evidence for sterol-independent regulation of low-density lipoprotein receptor activity in Hep-G2 cells
Q73550000	Evidence of macrophage foam cell formation by very low-density lipoprotein receptor: interferon-gamma inhibition of very low-density lipoprotein receptor expression and foam cell formation in macrophages
Q45016220	Evidence that density-dependent growth arrest is a two-stage process in WI-38 cells
Q24531838	Evolutionary conserved close linkage of the c-fes/fps proto-oncogene and genetic sequences encoding a receptor-like protein
Q35607500	Exon-Alu recombination deletes 5 kilobases from the low density lipoprotein receptor gene, producing a null phenotype in familial hypercholesterolemia
Q28306508	Exon/intron organization, chromosome localization, alternative splicing, and transcription units of the human apolipoprotein E receptor 2 gene
Q38601708	Exploring the complete mutational space of the LDL receptor LA5 domain using molecular dynamics: linking SNPs with disease phenotypes in familial hypercholesterolemia
Q38305764	Expression and folding of human very-low-density lipoprotein receptor fragments: neutralization capacity toward human rhinovirus HRV2.
Q36271262	Expression and regulation of apolipoprotein E receptors in the cells of the central nervous system in culture: A review
Q24295226	Expression and structure of the human NGF receptor
Q24312598	Expression cloning of a novel scavenger receptor from human endothelial cells
Q34143741	Expression of alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and scavenger receptor in human atherosclerotic lesions
Q33918423	Expression of an LDL receptor allele with two different mutations (E256K and I402T).
Q44895405	Expression of growth regulatory genes in primary human testicular neoplasms
Q37480208	Expression of human epidermal growth factor precursor cDNA in transfected mouse NIH 3T3 cells
Q73630854	Expression of very low density lipoprotein receptor mRNA in circulating human monocytes: its up-regulation by hypoxia
Q34560107	Extracellular signal-regulated kinase-dependent stabilization of hepatic low-density lipoprotein receptor mRNA by herbal medicine berberine
Q72294570	FH Afrikaner-3 LDL receptor mutation results in defective LDL receptors and causes a mild form of familial hypercholesterolemia
Q72569923	FH-Sydney 1 and 2: two novel frameshift mutations in exon 10 of the low-density lipoprotein receptor gene detected by heteroduplex formation
Q104736146	Familial Hypercholesterolemia in Russia: Three Decades of Genetic Studies
Q34048881	Familial hypercholesterolaemia as an example of early diagnosis of coronary artery disease risk by DNA techniques
Q72138652	Familial hypercholesterolaemia caused by a non-sense mutation in codon 329 of the LDL receptor gene
Q36275435	Familial hypercholesterolemia and response to statin therapy according to LDLR genetic background
Q43530662	Familial hypercholesterolemia in China. Identification of mutations in the LDL-receptor gene that result in a receptor-negative phenotype.
Q38985197	Familial hypercholesterolemia in Morocco: first report of mutations in the LDL receptor gene.
Q53875569	Familial hypercholesterolemia in South African Afrikaners. PvuII and StuI DNA polymorphisms in the LDL-receptor gene consistent with a predominating founder gene effect.
Q24797382	Familial hypercholesterolemia in St-Petersburg: the known and novel mutations found in the low density lipoprotein receptor gene in Russia
Q37741876	Familial hypercholesterolemia in a rhesus monkey pedigree: molecular basis of low density lipoprotein receptor deficiency
Q35076982	Familial hypercholesterolemia mutations in Petrozavodsk: no similarity to St. Petersburg mutation spectrum
Q57818471	Farnesoid X Receptor Activation by Obeticholic Acid Elevates Liver Low-Density Lipoprotein Receptor Expression by mRNA Stabilization and Reduces Plasma Low-Density Lipoprotein Cholesterol in Mice
Q28584207	Fibrates influence the expression of genes involved in lipoprotein metabolism in a tissue-selective manner in the rat
Q33848081	Finnish type of low density lipoprotein receptor gene mutation (FH-Helsinki) deletes exons encoding the carboxy-terminal part of the receptor and creates an internalization-defective phenotype
Q28647131	Flux analysis of cholesterol biosynthesis in vivo reveals multiple tissue and cell-type specific pathways
Q89063747	FlyXCDB-A Resource for Drosophila Cell Surface and Secreted Proteins and Their Extracellular Domains
Q37698136	Focal accumulation of an apolipoprotein B-based synthetic oligopeptide in the healing rabbit arterial wall
Q34382612	Folate receptors targeted to clathrin-coated pits cannot regulate vitamin uptake
Q30752588	Folding determinants of LDL receptor type A modules
Q45041602	Founder mutations in the LDL receptor gene contribute significantly to the familial hypercholesterolemia phenotype in the indigenous South African population of mixed ancestry
Q33681907	Four DNA polymorphisms in the LDL receptor gene: their genetic relationship and use in the study of variation at the LDL receptor locus.
Q72912457	Four new nucleotide sequence polymorphisms in the LDL receptor gene detected by SSCP analysis
Q72235635	Four novel partial deletions of LDL-receptor gene in Italian patients with familial hypercholesterolemia
Q71840901	Frequencies of the 5 PCR-based genetic markers LDLR, GYPA, HBGG, D7S8, and GC in a north Bavarian population
Q73177369	Frequencies of the five PCR-based genetic markers LDLR, GYPA, HBGG, D7S8 and GC in the population of Asturias (North Spain)
Q54601045	Frequencies of variants of candidate genes in different age groups of hypertensives.
Q35205250	From diet to DNA: dietary patterning of gene expression
Q70156049	Functional adaptations of transbilayer proteins
Q39503662	Functional and structural characteristics of EGF and its receptor and their relationship to transforming proteins
Q51746086	Functional characterization and classification of frequent low-density lipoprotein receptor variants.
Q41382412	Functional expression of human and mouse low density lipoprotein receptors in hybridomas
Q68786274	Further mapping of markers around the centromere of human chromosome 19
Q69808725	Gene analysis and its role in predicting susceptibility to disease
Q36566264	Gene conversion as a secondary mechanism of short interspersed element (SINE) evolution
Q34181152	Gene expression in macrophage-rich human atherosclerotic lesions. 15-lipoxygenase and acetyl low density lipoprotein receptor messenger RNA colocalize with oxidation specific lipid-protein adducts
Q33672301	Gene mapping and chromosome 19.
Q28288106	Gene transfer and molecular cloning of the rat nerve growth factor receptor
Q68164578	Gene-gene interaction between the low density lipoprotein receptor and apolipoprotein E loci affects lipid levels
Q38982764	Genetic Association of the Porcine C9 Complement Component with Hemolytic Complement Activity
Q52564391	Genetic analysis in a compound heterozygote family with familial hypercholesterolemia.
Q42521671	Genetic deletion of low density lipoprotein receptor impairs sterol-induced mouse macrophage ABCA1 expression. A new SREBP1-dependent mechanism
Q72611387	Genetic diagnosis with the denaturing gradient gel electrophoresis technique improves diagnostic precision in familial hypercholesterolemia
Q46824962	Genetic heterogeneity of autosomal dominant hypercholesterolemia in Mexico
Q40855553	Genetic mutations affecting human lipoproteins, their receptors, and their enzymes.
Q69371093	Genetic polymorphism of the apolipoprotein B gene locus influences serum LDL cholesterol level in familial hypercholesterolemia
Q39764306	Genetic polymorphisms related to glucose and triglyceride intolerance
Q41108660	Genetic structure and organization of the membrane attack complement components
Q37172163	Genetic variation and atherosclerosis
Q40299838	Genomewide association study on chronic periodontitis in Korean population: results from the Yangpyeong health cohort.
Q36011632	Genomic DNA with transformation-related activity and melanoma antigen expression
Q37422864	George Lyman Duff Memorial Lecture. Multifactorial etiology of hypercholesterolemia. Implications for prevention of coronary heart disease
Q37033150	Geranylgeranyl-regulated transport of the prenyltransferase UBIAD1 between membranes of the ER and Golgi
Q41528680	Giant lens, a gene involved in cell determination and axon guidance in the visual system of Drosophila melanogaster
Q50200558	Global flexibility in a sensory receptor: a site-directed cross-linking approach
Q24324257	Gp78, a membrane-anchored ubiquitin ligase, associates with Insig-1 and couples sterol-regulated ubiquitination to degradation of HMG CoA reductase
Q43816776	HMG-CoA reductase inhibitors reduce adhesion of human monocytes to endothelial cells
Q37740339	Half a Century Tales of Familial Hypercholesterolemia (FH) in Japan
Q84129312	Haplotype analyses, mechanism and evolution of common double mutants in the human LDL receptor gene
Q72660528	Haplotype analysis at the low density lipoprotein receptor locus in normal and familial hypercholesterolemia Norwegian subjects
Q33676491	Haplotype associations of three DNA polymorphisms at the human low density lipoprotein receptor gene locus in familial hypercholesterolaemia
Q33598443	Haplotypes identified by 10 DNA restriction fragment length polymorphisms at the human low density lipoprotein receptor gene locus
Q35892552	Hc-daf-2 encodes an insulin-like receptor kinase in the barber's pole worm, Haemonchus contortus, and restores partial dauer regulation
Q24322087	Hepatocyte growth factor activator inhibitor, a novel Kunitz-type serine protease inhibitor
Q36214767	Heterologous transmembrane and cytoplasmic domains direct functional chimeric influenza virus hemagglutinins into the endocytic pathway
Q41644499	High frequency of the Lebanese allele of the LDLr gene among Brazilian patients with familial hypercholesterolaemia
Q33750064	Higher incidence of mild cognitive impairment in familial hypercholesterolemia
Q43959430	Homozygous familial hypercholesterolemia in Lebanon: a genotype/phenotype correlation
Q47330918	How multi-scale structural biology elucidated context-dependent variability in ectodomain conformation along with the ligand capture and release cycle for LDLR family members.
Q69804954	Human ApoB-100 gene resides in the p23----pter region of chromosome 2
Q30403358	Human apolipoprotein B: structure of carboxyl-terminal domains, sites of gene expression, and chromosomal localization
Q24309556	Human apolipoprotein E receptor 2. A novel lipoprotein receptor of the low density lipoprotein receptor family predominantly expressed in brain
Q24629937	Human cytochrome P-450 4 mRNA and gene: part of a multigene family that contains Alu sequences in its mRNA
Q28115244	Human epidermal growth factor precursor: cDNA sequence, expression in vitro and gene organization
Q24610589	Human genes involved in cholesterol metabolism: chromosomal mapping of the loci for the low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl-coenzyme A reductase with cDNA probes
Q28615460	Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
Q70374923	Human interleukin 2 receptor (Tac antigen)
Q68368985	Human low density lipoprotein receptor expressed in Xenopus oocytes. Conserved signals for O-linked glycosylation and receptor-mediated endocytosis
Q46266191	Human low density lipoprotein receptor fragment. Successful refolding of a functionally active ligand-binding domain produced in Escherichia coli
Q36314748	Human low-density lipoprotein receptor gene and its regulation
Q24339643	Human lysozyme: sequencing of a cDNA, and expression and secretion by Saccharomyces cerevisiae
Q24535259	Human meprin beta: O-linked glycans in the intervening region of the type I membrane protein protect the C-terminal region from proteolytic cleavage and diminish its secretion
Q35572780	Human nidogen: complete amino acid sequence and structural domains deduced from cDNAs, and evidence for polymorphism of the gene
Q29619449	Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A
Q68093258	Human pregnancy-specific beta 1-glycoprotein: a new member of the carcinoembryonic antigen gene family
Q40833413	Human prostate cancer cells lack feedback regulation of low-density lipoprotein receptor and its regulator, SREBP2.
Q24315915	Human signal recognition particle (SRP) Alu-associated protein also binds Alu interspersed repeat sequence RNAs. Characterization of human SRP9
Q29615235	Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
Q41998866	IDENTIFICATION AND EXPRESSION ANALYSIS OF VITELLOGENIN RECEPTOR FROM THE WILD SILKWORM, Bombyx mandarina
Q73600046	Identification and characterization of LDL receptor gene mutations in hyperlipidemic Chinese
Q54572671	Identification and characterization of novel low-density lipoprotein receptor mutations of familial hypercholesterolaemia patients in Taiwan.
Q39870683	Identification and characterization of the viral interaction determinant of the subgroup A avian leukosis virus receptor
Q28744540	Identification and functional characterization in vivo of a novel splice variant of LDLR in rhesus macaques
Q36720307	Identification and molecular characterization of insulin-like growth factor binding proteins (IGFBP-1, -2, -3, -4, -5 and -6)
Q33845952	Identification and sequence analysis of a second form of prolactin receptor by molecular cloning of complementary DNA from rabbit mammary gland
Q69376763	Identification of LDL receptor gene marker associated with altered levels of LDL cholesterol and apolipoprotein B in baboons
Q34411329	Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglyceride synthesis
Q69915127	Identification of a deletion in the LDL receptor gene. A Finnish type of mutation
Q70096812	Identification of a deletion in the low density lipoprotein (LDL) receptor gene in a patient with familial hypercholesterolaemia
Q73332523	Identification of a double mutation in the low-density lipoprotein receptor gene causing familial hypercholesterolemia
Q24290727	Identification of a novel exon in apolipoprotein E receptor 2 leading to alternatively spliced mRNAs found in cells of the vascular wall but not in neuronal tissue
Q36369960	Identification of a novel major histocompatibility complex class II-restricted tumor antigen resulting from a chromosomal rearrangement recognized by CD4(+) T cells
Q71087468	Identification of a novel mutation in exon 13 of the LDL receptor gene causing familial hypercholesterolemia in two Spanish families
Q33867154	Identification of a point mutation in growth factor repeat C of the low density lipoprotein-receptor gene in a patient with homozygous familial hypercholesterolemia that affects ligand binding and intracellular movement of receptors
Q38343413	Identification of a second "French Canadian" LDL receptor gene deletion and development of a rapid method to detect both deletions.
Q68015548	Identification of a silent point mutation in the LDL-receptor gene by direct DNA sequencing
Q46528277	Identification of deletions and duplications in the low density lipoprotein receptor gene by MLPA.
Q41924391	Identification of deletions in the human low density lipoprotein receptor gene
Q73715661	Identification of four novel mutations of the low-density lipoprotein receptor gene in Korean patients with familial hypercholesterolemia
Q69636483	Identification of low density lipoprotein receptor binding domains of human apolipoprotein B-100: a proposed consensus LDL receptor binding sequence of apoB-100
Q34979050	Identification of luminal Loop 1 of Scap protein as the sterol sensor that maintains cholesterol homeostasis
Q33399670	Identification of mRNA binding proteins that regulate the stability of LDL receptor mRNA through AU-rich elements
Q38728542	Identification of roles for H264, H306, H439, and H635 in acid-dependent lipoprotein release by the LDL receptor.
Q40546017	Identification of the human rhinovirus serotype 1A binding site on the murine low-density lipoprotein receptor by using human-mouse receptor chimeras
Q28238318	Identification of the proteoglycan versican in aorta and smooth muscle cells by DNA sequence analysis, in situ hybridization and immunohistochemistry
Q74127852	Identification of three mutations in the low-density lipoprotein receptor gene causing familial hypercholesterolemia among French Canadians
Q73346250	Identification of two LDL receptor mutations causing familial hypercholesterolemia in Indian subjects
Q73441582	Identification of two novel LDL receptor gene defects in French-Canadian pediatric population: mutational analysis and biochemical studies
Q41065774	Immortalized rat proximal tubule cells produce membrane bound and soluble megalin
Q56969941	Immune Interferon Receptor: Chemical and Enzymatic Sensitivity
Q40925711	Impaired regulation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation in lovastatin-resistant cells
Q37130604	Importance of growth hormone for the induction of hepatic low density lipoprotein receptors
Q34492190	Improved survival of patients with homozygous familial hypercholesterolaemia treated with plasma exchange
Q26781446	In a Class of Their Own - RXFP1 and RXFP2 are Unique Members of the LGR Family
Q68406513	In vitro processing of tropoelastin: investigation of a possible transport function associated with the carboxy-terminal domain
Q42489938	In vivo and in vitro phosphorylation of murine lymphocyte differentiation antigen CD5.
Q68324641	In vivo regulation of low-density lipoprotein receptor and apolipoprotein B gene expressions by dietary fat and cholesterol in inbred strains of mice
Q40944660	Inactivation of the gene encoding the flagellar pocket protein, CRAM, in African trypanosomes
Q72210551	Increase of deoxycholate in supersaturated bile of patients with cholesterol gallstone disease and its correlation with de novo syntheses of cholesterol and bile acids in liver, gallbladder emptying, and small intestinal transit
Q35589157	Increased mRNA for low density lipoprotein receptor in livers of rabbits treated with 17 alpha-ethinyl estradiol
Q39563830	Initiation of coagulation by tissue factor
Q37345649	Insect vitellogenin/lipophorin receptors: molecular structures, role in oogenesis, and regulatory mechanisms
Q28251165	Insig-dependent ubiquitination and degradation of 3-hydroxy-3-methylglutaryl coenzyme a reductase stimulated by delta- and gamma-tocotrienols
Q44620965	Insig-dependent ubiquitination and degradation of mammalian 3-hydroxy-3-methylglutaryl-CoA reductase stimulated by sterols and geranylgeraniol
Q36796007	Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol
Q33880454	Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity
Q28285510	Insulin-like growth factor II receptor as a multifunctional binding protein
Q51763093	Interaction between the ligand-binding domain of the LDL receptor and the C-terminal domain of PCSK9 is required for PCSK9 to remain bound to the LDL receptor during endosomal acidification.
Q41508418	Interaction of a 39 kDa protein with the low-density-lipoprotein-receptor-related protein (LRP) on rat hepatoma cells
Q69780838	Interaction of human low density lipoprotein and apolipoprotein B with ternary lipid microemulsion. Physical and functional properties
Q58023267	Internalization of the anticoagulant thrombomodulin is constitutive and does not require a signal in the cytoplasmic domain
Q44534068	Internalization of the human immunodeficiency virus does not require the cytoplasmic domain of CD4.
Q34195375	Internalization-defective LDL receptors produced by genes with nonsense and frameshift mutations that truncate the cytoplasmic domain
Q35383835	International Union of Basic and Clinical Pharmacology. XCV. Recent advances in the understanding of the pharmacology and biological roles of relaxin family peptide receptors 1-4, the receptors for relaxin family peptides.
Q39984867	Intracellular trafficking of LRP9 is dependent on two acidic cluster/dileucine motifs
Q39737311	Introduction to the plasma lipoproteins
Q39764520	Intron-dependent evolution: preferred types of exons and introns
Q54765769	Investigation of the distribution and changes of VLDLR subtype in fibrotic cardiac muscles.
Q36756891	Involvement of second messengers in regulation of the low-density lipoprotein receptor gene
Q42819400	Is vitellogenin an ancestor of apolipoprotein B-100 of human low-density lipoprotein and human lipoprotein lipase?
Q24563737	Isolation and characterization of a cDNA encoding the low molecular weight insulin-like growth factor binding protein (IBP-1)
Q24610708	Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure
Q69441252	Isolation and characterization of four heparin-binding cyanogen bromide peptides of human plasma apolipoprotein B
Q24613496	Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen
Q36773167	Isolation and cloning by a polymerase chain reaction of a genomic DNA fragment of the human slow skeletal troponin (TNNT1) gene
Q69647871	Isolation of a proteolytically derived domain of the insulin receptor containing the major site of cross-linking/binding
Q38338865	Isolation of an Alu repetitive DNA binding protein and effect of CpG methylation on binding to its recognition sequence
Q28115591	Isolation of cDNA clones coding for human tissue factor: primary structure of the protein and cDNA
Q24296254	Isolation of complementary DNA clones encoding the human lymphocyte glycoprotein T1/Leu-1
Q28271399	Isolation of mutant cells lacking Insig-1 through selection with SR-12813, an agent that stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
Q36489597	Isolation of the human insulin-like growth factor genes: insulin-like growth factor II and insulin genes are contiguous
Q36836992	Italian population data on the loci LDLR, GYPA, HBGG, D7S8 and GC.
Q30583186	Jordanian population data on the PCR-based loci: LDLR, GYPA, HBGG, D7S8 and GC.
Q41493922	Ketoconazole and 25-hydroxycholesterol produce reciprocal changes in the rate of transcription of the human LDL receptor gene
Q58842957	LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation
Q24321832	LDL receptor/lipoprotein recognition: endosomal weakening of ApoB and ApoE binding to the convex face of the LR5 repeat
Q41621196	LDL receptors in keratinocytes
Q68802373	LDL-receptor mRNA expression in liver regeneration after partial hepatectomy
Q35938094	LDL-receptor mutations in Europe
Q34650934	LDLR Database (second edition): new additions to the database and the software, and results of the first molecular analysis
Q33521909	LDLR expression and localization are altered in mouse and human cell culture models of Alzheimer's disease
Q28507759	LRAD3, a novel low-density lipoprotein receptor family member that modulates amyloid precursor protein trafficking
Q72764283	LRP and the receptor-mediated endocytosis of plasminogen activators
Q41941559	Ligand selectivity of 105 kDa and 130 kDa lipoprotein-binding proteins in vascular-smooth-muscle-cell membranes is unique
Q42675685	Ligand-binding domains in vitellogenin receptors and other LDL-receptor family members share a common ancestral ordering of cysteine-rich repeats
Q63915864	Ligand-receptor interactions of the low density lipoprotein receptor-related protein, a multi-ligand endocytic receptor
Q46001391	Linkage disequilibrium between DNA markers at the low-density lipoprotein receptor gene.
Q33889684	Lipid transport biochemistry and its role in energy production
Q39593380	Lipid-lowering and antioxidant activities of Jiang-Zhi-Ning in Traditional Chinese Medicine
Q39700049	Lipoproteins and atherosclerosis
Q43711521	Lipoproteins, malignancy, and anticancer agents.
Q24611424	Liver transplantation to provide low-density-lipoprotein receptors and lower plasma cholesterol in a child with homozygous familial hypercholesterolemia
Q44059750	Localization of PEPD to the long arm of chromosome 19.
Q73977884	Localization of the N-terminal domain of the low density lipoprotein receptor
Q61981672	Location of mouse and human genes corresponding to conserved canine olfactory receptor gene subfamilies
Q64380847	Long-term reversal of hypercholesterolemia in low density lipoprotein receptor (LDLR)-deficient mice by adenovirus-mediated LDLR gene transfer combined with CD154 blockade
Q77739511	Lovastatin decreases the receptor-mediated degradation of acetylated and oxidized LDLs in human blood monocytes during the early stage of differentiation into macrophages
Q71210052	Lovastatin reduces expression of the combined adhesion and scavenger receptor CD36 in human monocytic cells
Q29014323	Low Density Lipoprotein Receptor-related Protein/[IMAGE][IMAGE]-Macroglobulin Receptor Mediates the Cellular Internalization and Degradation of Thrombospondin
Q70883747	Low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase mRNA levels are coordinately reduced in human renal cell carcinoma
Q36531164	Low density lipoprotein receptor and cation-independent mannose 6-phosphate receptor are transported from the cell surface to the Golgi apparatus at equal rates in PC12 cells
Q40972546	Low density lipoprotein receptor as a candidate receptor for hepatitis C virus
Q24609758	Low density lipoprotein receptor-related protein mediates uptake of cholesteryl esters derived from apoprotein E-enriched lipoproteins
Q37149561	Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor is an hepatic receptor for tissue-type plasminogen activator
Q33758610	Low density lipoprotein uptake: holoparticle and cholesteryl ester selective uptake
Q77996963	Low density lipoprotein-receptor plays a major role in the binding of very low density lipoproteins and their remnants on HepG2 cells
Q54131876	Low-density lipoprotein endocytosis. I. Influence of the multivalent ligand cationized ferritin on normal and receptor-negative human fibroblasts.
Q43714958	Low-density lipoprotein receptor gene mutation analysis and structure-function correlation in an Omani arab family with familial hypercholesterolemia
Q38139022	Low-density lipoprotein receptors in liver: old acquaintances and a newcomer
Q53264107	Low-density lipoprotein-mimicking nanoparticles for tumor-targeted theranostic applications.
Q36196801	Lrp13 is a novel vertebrate lipoprotein receptor that binds vitellogenins in teleost fishes
Q60045905	Lucky, times ten: A career in Texas science
Q56531227	Lysosomal cholesterol export reconstituted from fragments of Niemann-Pick C1
Q41680284	MIG-13 positions migrating cells along the anteroposterior body axis of C. elegans
Q47730212	Major components of a sea urchin block to polyspermy are structurally and functionally conserved
Q50635229	Mapping key regions of the RXFP2 low-density lipoprotein class-A module that are involved in signal activation.
Q71601016	Mapping of the 19p13 breakpoint in an ovarian carcinoma between the INSR and TCF3 loci
Q61982671	Marked association of a RFLP for the low density lipoprotein receptor gene with obesity in essential hypertensives
Q36814824	Mechanism and consequences of the duplication of the human C4/P450c21/gene X locus
Q41833733	Mechanism of LDL binding and release probed by structure-based mutagenesis of the LDL receptor
Q38289814	Mechanism of low density lipoprotein (LDL) release in the endosome: implications of the stability and Ca2+ affinity of the fifth binding module of the LDL receptor.
Q36767518	Mechanisms of disease: genetic causes of familial hypercholesterolemia
Q41758467	Megalin-mediated endocytosis in renal proximal tubule
Q35077224	Members of the low density lipoprotein receptor family mediate cell entry of a minor-group common cold virus
Q57212598	Membrane attack complex-associated molecules from redlip mullet (Liza haematocheila): Molecular characterization and transcriptional evidence of C6, C7, C8β, and C9 in innate immunity
Q24318004	Membrane cofactor protein of the complement system: alternative splicing of serine/threonine/proline-rich exons and cytoplasmic tails produces multiple isoforms that correlate with protein phenotype
Q40737575	Membrane proteins that protect against complement lysis
Q41718862	Membrane receptors for endocytosis in the renal proximal tubule.
Q38181066	Membrane receptors for extracellular matrix macromolecules: relationship to cell adhesion and tumor metastasis
Q40939802	Membrane topology of S2P, a protein required for intramembranous cleavage of sterol regulatory element-binding proteins
Q24293757	Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase
Q28075743	Metabolism and Modification of Apolipoprotein B-Containing Lipoproteins Involved in Dyslipidemia and Atherosclerosis
Q24628996	Mevinolin, an inhibitor of cholesterol synthesis, induces mRNA for low density lipoprotein receptor in livers of hamsters and rabbits
Q37379761	Mitotic Golgi disassembly is required for bipolar spindle formation and mitotic progression
Q44513963	Modified linear polyethylenimine-cholesterol conjugates for DNA complexation
Q35236987	Modular transposition and the dynamical structure of eukaryote regulatory evolution
Q42078686	Modulation of complement regulatory function and measles virus receptor function by the serine-threonine-rich domains of membrane cofactor protein (CD46).
Q42475999	Modulation of juxtamembrane cleavage ("shedding") of angiotensin-converting enzyme by stalk glycosylation: evidence for an alternative shedding protease.
Q37201945	Molecular Genetics of Familial Hypercholesterolemia
Q58159389	Molecular Genetics of Hypercholesterolemia
Q48275942	Molecular analysis of deletions in the human beta-globin gene cluster: deletion junctions and locations of breakpoints
Q39737316	Molecular and cell biology of lipoprotein biosynthesis
Q36401301	Molecular and cellular mechanisms of receptor-mediated endocytosis
Q27742097	Molecular basis of familial hypercholesterolaemia from structure of LDL receptor module
Q36265507	Molecular basis of familial hypercholesterolemia: An Indian experience
Q39819750	Molecular biology in arteriosclerosis research
Q39559628	Molecular biology of human apolipoprotein B and related diseases.
Q38327290	Molecular biology of human apolipoproteins B and E and associated diseases of lipoprotein metabolism.
Q24567485	Molecular characterization of a gene of the 'EGF family' expressed in undifferentiated human NTERA2 teratocarcinoma cells
Q34556697	Molecular characterization of human Ro/SS-A antigen. Amino terminal sequence of the protein moiety of human Ro/SS-A antigen and immunological activity of a corresponding synthetic peptide
Q35644390	Molecular characterization of minor gene rearrangements in Finnish patients with heterozygous familial hypercholesterolemia: identification of two common missense mutations (Gly823-->Asp and Leu380-->His) and eight rare mutations of the LDL receptor
Q44460218	Molecular characterization of the first avian LDL receptor: role in sterol metabolism of ovarian follicular cells.
Q37378425	Molecular characterization of the mosquito vitellogenin receptor reveals unexpected high homology to the Drosophila yolk protein receptor
Q22004159	Molecular cloning and characterization of LR3, a novel LDL receptor family protein with mitogenic activity
Q22254880	Molecular cloning and characterization of the human dbl proto-oncogene: evidence that its overexpression is sufficient to transform NIH/3T3 cells
Q30359832	Molecular cloning and developmental expression pattern of the vitellogenin receptor from the cockroach, Leucophaea maderae.
Q24303604	Molecular cloning and expression of a receptor for human tumor necrosis factor
Q42816749	Molecular cloning and nucleotide sequence of cDNA encoding a functional murine low-density-lipoprotein receptor
Q42607414	Molecular cloning and partial characterization of an ovarian receptor with seven ligand binding repeats, an orthologue of low-density lipoprotein receptor, in the cutthroat trout (Oncorhynchus clarki).
Q34638898	Molecular cloning and sequence analysis of the catalytic subunit of bovine type 2A protein phosphatase
Q36424232	Molecular cloning and structure of the human interleukin 2 receptor gene
Q34585890	Molecular cloning of Ly-1, a membrane glycoprotein of mouse T lymphocytes and a subset of B cells: molecular homology to its human counterpart Leu-1/T1 (CD5).
Q28299349	Molecular cloning of cDNA for human complement component C1s. The complete amino acid sequence
Q30406574	Molecular cloning of human apolipoprotein B cDNA.
Q33894003	Molecular cloning of the large subunit of transforming growth factor type beta masking protein and expression of the mRNA in various rat tissues
Q50659511	Molecular cloning, characterization and regulation of the cockroach vitellogenin receptor during oogenesis.
Q34257677	Molecular counting of low-density lipoprotein particles as individuals and small clusters on cell surfaces
Q45759199	Molecular evolution of the carbonic anhydrase genes: calculation of divergence time for mouse carbonic anhydrase I and II.
Q78476892	Molecular genetic analysis of familial hypercholesterolemia: spectrum and regional difference of LDL receptor gene mutations in Japanese population
Q73589355	Molecular genetic testing for familial hypercholesterolemia: spectrum of LDL receptor gene mutations in The Netherlands
Q28207758	Molecular genetics of the LDL receptor gene in familial hypercholesterolemia
Q38162125	Molecular mechanisms of cytolysis by complement and by cytolytic lymphocytes
Q37972887	Molecular pathology of familial hypercholesterolemia, related dyslipidemias and therapies beyond the statins
Q34557404	More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration
Q28237952	Mouse and human CD14 (myeloid cell-specific leucine-rich glycoprotein) primary structure deduced from cDNA clones
Q37121194	Mouse macrophage receptor for acetylated low density lipoprotein: demonstration of a fully functional subunit in the membrane and with purified receptor
Q28238473	Mouse very-low-density-lipoprotein receptor (VLDLR) cDNA cloning, tissue-specific expression and evolutionary relationship with the low-density-lipoprotein receptor
Q35586870	Multiple crm- mutations in familial hypercholesterolemia. Evidence for 13 alleles, including four deletions
Q36424372	Murine plasma cell membrane antigen PC-1: molecular cloning of cDNA and analysis of expression
Q33878706	Mutant oocytic low density lipoprotein receptor gene family member causes atherosclerosis and female sterility
Q58143918	Mutant transcripts of the LDL receptor gene: mRNA structure and quantity
Q40419629	Mutation G805R in the transmembrane domain of the LDL receptor gene causes familial hypercholesterolemia by inducing ectodomain cleavage of the LDL receptor in the endoplasmic reticulum
Q26269836	Mutation in LDL receptor: Alu-Alu recombination deletes exons encoding transmembrane and cytoplasmic domains
Q50950950	Mutation p.L799R in the LDLR, which affects the transmembrane domain of the LDLR, prevents membrane insertion and causes secretion of the mutant LDLR.
Q61387686	Mutation screening of the LDLR gene and ApoB gene in patients with a phenotype of familial hypercholesterolemia and normal values in a functional LDL receptor/apolipoprotein B assay
Q38346504	Mutational analysis of the ligand binding domain of the low density lipoprotein receptor
Q38939832	Mutational heterogeneity in low-density lipoprotein receptor gene related to familial hypercholesterolemia in Morocco.
Q68616089	Mutations in the low density lipoprotein receptor gene in Japanese patients with familial hypercholesterolemia
Q77393956	Mutations in the low-density lipoprotein receptor gene in Swedish familial hypercholesterolaemia patients: clinical expression and treatment response
Q81067930	Mutations of the low-density-lipoprotein receptor gene and familial hypercholesterolemia
Q46603259	Native and oxidized low-density lipoproteins stimulate endothelin-converting enzyme-1 expression in human endothelial cells.
Q44744920	Neu differentiation factor: a transmembrane glycoprotein containing an EGF domain and an immunoglobulin homology unit
Q28116105	Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing
Q73507862	Neurotoxicity of the 22 kDa thrombin-cleavage fragment of apolipoprotein E and related synthetic peptides is receptor-mediated
Q93697284	New genetics of the hyperlipidaemias and diabetes
Q77393946	New type of the internalization-defective low-density lipoprotein receptor owing to two-nucleotide deletion (2199delCA or 2201delCA) in Japanese patients with familial hypercholesterolaemia
Q69821234	New variant of low density lipoprotein receptor gene. FH-Tonami
Q34139012	No requirement for localized Nudel protein expression in Drosophila embryonic axis determination
Q68751567	Novel gene mutations at the low density lipoprotein receptor locus: FH-Kanazawa and FH-Okayama
Q43216594	Novel mutations identification in exon 4 of LDLR gene in patients with moderate hypercholesterolemia in a Venezuelan population
Q36952435	Nucleotide sequence and expression in vitro of cDNA derived from mRNA of int-1, a provirally activated mouse mammary oncogene
Q40521487	Nucleotide sequence of the rat low density lipoprotein receptor cDNA.
Q46609130	O-glycosylation and stability. Unfolding of glucoamylase induced by heat and guanidine hydrochloride
Q38330153	O-glycosylation in Aspergillus glucoamylase. Conformation and role in binding
Q36876622	O-linked glycosylation of retroviral envelope gene products
Q70160601	Oncogene proteins and the insulin receptor
Q39547546	Oncogenes and urological malignancies: implications for the future
Q28361629	Optional exon in the 5'-untranslated region of 3-hydroxy-3-methylglutaryl coenzyme A synthase gene: conserved sequence and splicing pattern in humans and hamsters
Q34175241	Overexpression of low density lipoprotein (LDL) receptor eliminates LDL from plasma in transgenic mice
Q73409190	Overexpression of low density lipoprotein receptor eliminates apolipoprotein B100-containing lipoproteins from circulation and markedly prevents early atherogenesis in apolipoprotein E-deficient mice
Q68000543	Overexpression of low density lipoprotein receptor on Chinese hamster ovary cells generates foam cells
Q98392269	Ovotransferrin Exhibits Osteogenic Activity Partially via LDL Receptor-related Protein 1 (LRP1) Activation in MC3T3-E1 Cells
Q35042005	Oxidized low-density lipoproteins: what is understood and what remains to be clarified
Q77601534	Oxidized phospholipids as a new landmark in atherosclerosis
Q36851164	Oxysterols, cholesterol homeostasis, and Alzheimer disease
Q33807223	Oxysterols: modulators of cholesterol metabolism and other processes
Q41691951	PCR primers for human chromosomes: reagents for the rapid analysis of somatic cell hybrids
Q36847452	Pathway of B1-Alu expression in microinjected oocytes: Xenopus laevis proteins associated with nuclear precursor and processed cytoplasmic RNAs
Q36213211	Perinuclear location and recycling of epidermal growth factor receptor kinase: immunofluorescent visualization using antibodies directed to kinase and extracellular domains
Q53207672	Perlecan: the multidomain heparan sulphate proteoglycan of basement membrane and extracellular matrix.
Q71637229	Phenotypic presentation of the FH-Cincinnati type 5 low density lipoprotein receptor mutation
Q42685552	Phorbol ester-induced juxtamembrane cleavage of angiotensin-converting enzyme is not inhibited by a stalk containing intrachain disulfides.
Q90434768	Phosphatidylinositol-(4,5)-Bisphosphate Regulates Plasma Cholesterol Through LDL (Low-Density Lipoprotein) Receptor Lysosomal Degradation
Q34325673	Phospholipase D2 is required for efficient endocytic recycling of transferrin receptors
Q51562587	Plasma anti-α-galactoside antibody mediates lipoprotein(a) binding to macrophages.
Q68521024	Plasma cholesterol-lowering activity of monocyte colony-stimulating factor (M-CSF)
Q34869224	Pleiotrophin as a central nervous system neuromodulator, evidences from the hippocampus.
Q36850216	Point mutation in luminal loop 7 of Scap protein blocks interaction with loop 1 and abolishes movement to Golgi
Q35247208	Polymorphic DNA haplotypes at the LDL receptor locus
Q35194175	Polymorphic haplotypes and recombination rates at the LDL receptor gene locus in subjects with and without familial hypercholesterolemia who are from different populations
Q37555170	Polymorphism and evolution of Alu sequences in the human low density lipoprotein receptor gene
Q36817143	Population data on the PCR-based loci LDLR GYPA, HBGG, D7S8, Gc, HLA-DQA1, and D1S80 from Arabs from Dubai
Q36216556	Potassium-dependent assembly of coated pits: new coated pits form as planar clathrin lattices
Q35756612	Potential role of the low-density lipoprotein receptor family as mediators of cellular drug uptake
Q34347050	Preferential sites of proteolytic cleavage of bovine, human and rat thyroglobulin. The use of limited proteolysis to detect solvent-exposed regions of the primary structure
Q67533720	Prevalence and geographical distribution of major LDL receptor gene rearrangements in Finland
Q77322368	Prevalence of Lithuanian mutation among St. Petersburg Jews with familial hypercholesterolemia
Q72189535	Primary dual defect of cholesterol and bile acid metabolism in liver of patients with intrahepatic calculi
Q48376190	Primary structure of bovine thyroglobulin deduced from the sequence of its 8,431-base complementary DNA.
Q33929176	Primary structure of the gene for the murine Ia antigen-associated invariant chains (Ii). An alternatively spliced exon encodes a cysteine-rich domain highly homologous to a repetitive sequence of thyroglobulin
Q42616828	Products of the unc-52 gene in Caenorhabditis elegans are homologous to the core protein of the mammalian basement membrane heparan sulfate proteoglycan
Q39702041	Progress in understanding mechanisms of the serum cholesterol risk factor in atherosclerosis
Q43631774	Protective effects of Saiko-ka-ryukotsu-borei-to (Chai-Hu-Jia-Long-Gu-Mu-Li-Tang) against atherosclerosis in Kurosawa and Kusanagi-hypercholesterolemic (KHC) rabbits
Q68763588	Protein domains of the low density lipoprotein receptor
Q71477938	Protein folding and calcium binding defects arising from familial hypercholesterolemia mutations of the LDL receptor
Q39503984	Protein kinase activity of the insulin receptor
Q30403445	Proteins, exons and molecular evolution
Q40910738	Proteoglycans of basement membranes
Q36871737	Proteolytic release of membrane proteins: studies on a membrane-protein-solubilizing activity in CHO cells
Q36813409	Proteolytic release of membrane-bound angiotensin-converting enzyme: role of the juxtamembrane stalk sequence
Q101565149	Proteostasis Regulation in the Endoplasmic Reticulum: An Emerging Theme in the Molecular Pathology and Therapeutic Management of Familial Hypercholesterolemia
Q40419031	Pst I RFLP close to the LDL receptor gene
Q41979573	Purification of a putative lipoprotein receptor from Schistosoma japonicum adult worms
Q69927422	Pvu II polymorphism of low density lipoprotein receptor gene and familial hypercholesterolemia. Study of Italians
Q34324828	Quantitation of mRNA by the polymerase chain reaction
Q38350285	Quantitation of the sterol regulatory element-binding protein mRNA in mononuclear blood cells by competitive RT-PCR
Q40567291	RFLP for the human LDL receptor gene (LDLR): Bst EII.
Q37716069	RNAi therapeutics for CNS disorders
Q36597924	RNAi therapy for neurodegenerative diseases.
Q24293268	Rabbit very low density lipoprotein receptor: a low density lipoprotein receptor-like protein with distinct ligand specificity
Q69352440	Radiation inactivation of membrane components and molecular mass determination by target analysis
Q69583976	Radiation target analysis of glycoproteins
Q104267397	Rapid degradation of GRASP55 and GRASP65 reveals their immediate impact on the Golgi structure
Q68162143	Rearrangements in the LDL receptor gene in Dutch familial hypercholesterolemic patients and the presence of a common 4 kb deletion
Q89775505	Recent advances in genome editing for cardiovascular disease
Q43916702	Receptor mediated yolk protein uptake in the crab Scylla serrata: crustacean vitellogenin receptor recognizes related mammalian serum lipoproteins
Q71246704	Receptor-associated protein is a folding chaperone for low density lipoprotein receptor-related protein
Q34554723	Receptor-independent low density lipoprotein transport in the rat in vivo. Quantitation, characterization, and metabolic consequences
Q69875511	Receptor-mediated endocytosis
Q40886690	Receptor-mediated endocytosis in the procyclic form of Trypanosoma brucei
Q28283978	Receptors compete for adaptors found in plasma membrane coated pits
Q33647536	Receptors for the host low density lipoproteins on the hemoflagellate Trypanosoma brucei: purification and involvement in the growth of the parasite
Q40969377	Recognition of the carboxyl-terminal signal for GPI modification requires translocation of its hydrophobic domain across the ER membrane
Q40966970	Recombinant soluble low-density lipoprotein receptor fragment inhibits common cold infection
Q84829637	Reduced penetrance of autosomal dominant hypercholesterolemia in a high percentage of families: importance of genetic testing in the entire family
Q69890182	Regional localisations and linkage relationships of seven RFLPs and myotonic dystrophy on chromosome 19
Q37454290	Regulated endoplasmic reticulum-associated degradation of a polytopic protein: p97 recruits proteasomes to Insig-1 before extraction from membranes
Q28320785	Regulation of HMG-CoA reductase, apoprotein-B and LDL receptor gene expression by the hypocholesterolemic drugs simvastatin and ciprofibrate in Hep G2, human and rat hepatocytes
Q41624566	Regulation of LDL receptor, apoB, and apoE protein and mRNA in Hep G2 cells
Q41467015	Regulation of intracellular cholesterol metabolism is defective in lymphoblasts from Niemann-Pick type C and type D patients.
Q39027013	Regulation of low density lipoprotein receptor and cytochrome P-450scc mRNA levels in human granulosa cells
Q52182903	Regulation of low density lipoprotein receptor mRNA levels by estradiol 17beta and chorionic gonadotropin in human placenta.
Q41670480	Regulation of low-density lipoprotein receptor expression during keratinocyte differentiation
Q71841082	Regulation of low-density lipoprotein receptors and assessment of their functional role in Burkitt's lymphoma cells
Q69206595	Regulation of low-density lipoprotein receptors: implications for pathogenesis and therapy of hypercholesterolemia and atherosclerosis
Q69075101	Regulation of low-density-lipoprotein-receptor mRNA by insulin in human hepatoma Hep G2 cells
Q73201506	Regulation of pathways determining cholesterol availability in the baboon placenta with advancing gestation
Q33836673	Regulation of the low density lipoprotein receptor and hydroxymethylglutaryl coenzyme A reductase genes by protein kinase C and a putative negative regulatory protein
Q30404028	Relationships between the gene and protein structure in human complement component C9.
Q38072905	Relaxin family peptides and their receptors
Q38160366	Removal of the Alu structural domain from signal recognition particle leaves its protein translocation activity intact.
Q57454815	Replacement of cysteine at position 46 in the first cysteine-rich repeat of the LDL receptor impairs apolipoprotein recognition
Q68303284	Retroviral vector-mediated in vivo expression of low-density-lipoprotein receptors in the Watanabe heritable hyperlipidemic rabbit
Q64382900	Reversal of hypercholesterolemia in low density lipoprotein receptor knockout mice by adenovirus-mediated gene transfer of the very low density lipoprotein receptor
Q39774353	Revision of consensus sequence of human Alu repeats--a review
Q35312862	Role of cellular cholesterol metabolism in vascular cell calcification
Q72396953	Role of common genetic polymorphisms in the LDL receptor gene in affecting plasma cholesterol levels in the general population
Q40782405	Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans.
Q46264980	Role of receptor-associated 39/45 kD protein in active Heymann nephritis
Q35553097	Role of the low density lipoprotein receptor in the flux of cholesterol through the plasma and across the tissues of the mouse
Q33888529	Roles for trafficking and O-linked glycosylation in the turnover of model cell surface proteins
Q38598477	Roles of Lipoproteins and Apolipoproteins in Particle Formation of Hepatitis C Virus
Q38985597	Roles of lipoprotein and apolipoprotein in HCV infection
Q50721166	SFE1, a constituent of the fertilization envelope in the sea urchin is made by oocytes and contains low-density lipoprotein-receptor-like repeats.
Q38360185	SREBP-1 mediates activation of the low density lipoprotein receptor promoter by insulin and insulin-like growth factor-I.
Q24310555	SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis
Q37651101	SRL-Coated PAMAM Dendrimer Nano-Carrier for Targeted Gene Delivery to the Glioma Cells and Competitive Inhibition by Lactoferrin
Q24305281	ST7 is a novel low-density lipoprotein receptor-related protein (LRP) with a cytoplasmic tail that interacts with proteins related to signal transduction pathways
Q90436782	Schnyder Corneal Dystrophy-Associated UBIAD1 is Defective in MK-4 Synthesis and Resists Autophagy-Mediated Degradation
Q70221901	Screening for a prevalent LDL receptor mutation in patients with severe hypercholesterolaemia
Q72333208	Screening for known mutations in the LDL receptor gene causing familial hypercholesterolemia
Q33676595	Screening for mutations in exon 4 of the LDL receptor gene: identification of a new deletion mutation.
Q72231133	Screening for point mutations in exon 10 of the low density lipoprotein receptor gene by analysis of single-strand conformation polymorphisms: detection of a nonsense mutation-FH469-->Stop
Q35020203	Sequence and structure of human rhinoviruses reveal the basis of receptor discrimination
Q24339620	Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors
Q24290202	Sequence similarities between a novel putative G protein-coupled receptor and Na+/Ca2+ exchangers define a cation binding domain
Q69868179	Sequence similarity between epidermal growth factor precursor and atrial natriuretic factor precursor
Q64085599	Sequential disruption of ALV host receptor genes reveals no sharing of receptors between ALV subgroups A, B, and J
Q48224334	Serial Alu sequence transposition interrupting a human B creatine kinase pseudogene
Q44303467	Serine proteases and their homologs in the Drosophila melanogaster genome: an initial analysis of sequence conservation and phylogenetic relationships
Q36720405	Serpin A1 and CD91 as host instruments against HIV-1 infection: are extracellular antiviral peptides acting as intracellular messengers?
Q71725568	Seven DNA polymorphisms in the LDL receptor gene: application to the study of familial hypercholesterolemia in Spain
Q78753350	Sex and hormonal status modulate the effects of psyllium on plasma lipids and monocyte gene expression in humans
Q35228909	Signal Transduction by the Colony-Stimulating Factor-1 Receptor; Comparison to Other Receptor Tyrosine Kinases
Q48369441	Similarity of protein encoded by the human c-erb-B-2 gene to epidermal growth factor receptor
Q74455513	Simplified detection of a mutation causing familial hypercholesterolaemia throughout Britain: evidence for an origin in a common distant ancestor
Q33595177	Six DNA polymorphisms in the low density lipoprotein receptor gene: their genetic relationship and an example of their use for identifying affected relatives of patients with familial hypercholesterolaemia
Q39718607	Software and database for the analysis of mutations in the human LDL receptor gene
Q52566959	Soluble LDL minireceptors. Minimal structure requirements for recognition of minor group human rhinovirus.
Q27632923	Solution structure of the LDL receptor EGF-AB pair: a paradigm for the assembly of tandem calcium binding EGF domains
Q27621667	Solution structure of the sixth LDL-A module of the LDL receptor
Q33731030	Somatic gene therapy for dyslipidemias
Q34438706	Sorting an LDL receptor with bound PCSK9 to intracellular degradation
Q37372140	SpCoel1: a sea urchin profilin gene expressed specifically in coelomocytes in response to injury
Q83655936	Species differences of macrophage very low-density-lipoprotein (VLDL) receptor protein expression
Q39684168	Species-specific receptor recognition by a minor-group human rhinovirus (HRV): HRV serotype 1A distinguishes between the murine and the human low-density lipoprotein receptor
Q42806879	Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor
Q40817578	Specificity of binding of clathrin adaptors to signals on the mannose-6-phosphate/insulin-like growth factor II receptor
Q40895692	Sphingolipid-cholesterol rafts diffuse as small entities in the plasma membrane of mammalian cells
Q35651427	Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8.
Q37270579	Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells
Q24306877	Sterol-regulated degradation of Insig-1 mediated by the membrane-bound ubiquitin ligase gp78
Q92094495	Strategies to prevent cleavage of the linker region between ligand-binding repeats 4 and 5 of the LDL receptor
Q24339526	Structural alteration of viral homologue of receptor proto-oncogene fms at carboxyl terminus
Q39698408	Structural and functional aspects of epidermal growth factor (EGF) and its receptor.
Q92527244	Structural basis for itraconazole-mediated NPC1 inhibition
Q41916799	Structural basis for ligand capture and release by the endocytic receptor ApoER2.
Q27660190	Structural basis for specific recognition of reelin by its receptors
Q33850785	Structural homology of complement protein C6 with other channel-forming proteins of complement
Q77293454	Structural independence of ligand-binding modules five and six of the LDL receptor
Q28292154	Structural requirements for PCSK9-mediated degradation of the low-density lipoprotein receptor
Q52250384	Structural studies of detergent-solubilized and vesicle-reconstituted low-density lipoprotein (LDL) receptor.
Q35205572	Structure and dynamics of polypeptides and proteins in lipid membranes
Q24556219	Structure and expression of human thrombomodulin, a thrombin receptor on endothelium acting as a cofactor for protein C activation
Q34650688	Structure and physiologic function of the low-density lipoprotein receptor
Q35610668	Structure of a bovine gene for P-450c21 (steroid 21-hydroxylase) defines a novel cytochrome P-450 gene family
Q27625423	Structure of human rhinovirus serotype 2 (HRV2)
Q28646488	Structure of human steroid 21-hydroxylase genes
Q34688924	Structure of integrin, a glycoprotein involved in the transmembrane linkage between fibronectin and actin
Q27640067	Structure of the LDL receptor extracellular domain at endosomal pH
Q24643048	Structure of the axonal surface recognition molecule neurofascin and its relationship to a neural subgroup of the immunoglobulin superfamily
Q69404071	Structure of the low-density lipoprotein receptor-related protein (LRP) promoter
Q29616545	Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors
Q36465438	Studies on rationales for an expert system approach to the interpretation of protein sequence data. Preliminary analysis of the human epidermal growth factor receptor
Q24297663	Surface location and high affinity for calcium of a 500-kd liver membrane protein closely related to the LDL-receptor suggest a physiological role as lipoprotein receptor
Q36726735	Swiss population data on the loci HLA-DQ alpha, LDLR, GYPA, HBGG, D7S8, Gc and D1S80.
Q36848801	Tandemly repeated exons encode 81-base repeats in multiple, developmentally regulated Schistosoma mansoni transcripts
Q57248646	TaqI polymorphism in the LDL receptor gene and a TaqI 1.5-kb band associated with familial hypercholesterolemia
Q35096270	Targeted disruption of the idol gene alters cellular regulation of the low-density lipoprotein receptor by sterols and liver x receptor agonists
Q44640632	Targeting of biotinylated compounds to its target tissue using a low-density lipoprotein receptor-avidin fusion protein
Q39563083	The 'BN2' gene, a regulator for the onset of chromosome condensation
Q54336249	The Arabic allele: a single base pair substitution activates a 10-base downstream cryptic splice acceptor site in exon 12 of LDLR and severely decreases LDLR expression in two unrelated Arab families with familial hypercholesterolemia.
Q21735933	The DNA sequence and biology of human chromosome 19
Q44815679	The Drosophila EGF receptor gene homolog: conservation of both hormone binding and kinase domains
Q34624656	The Drosophila yolkless gene encodes a vitellogenin receptor belonging to the low density lipoprotein receptor superfamily
Q68434690	The Finnish type of the LDL receptor gene mutation: molecular characterization of the deleted gene and the corresponding mRNA
Q35245419	The Gordon Wilson Lecture. Plasma cholesterol: atherogenesis and mortality
Q34196707	The J.D. mutation in familial hypercholesterolemia: amino acid substitution in cytoplasmic domain impedes internalization of LDL receptors
Q24658039	The LDL receptor
Q26269835	The LDL receptor gene: a mosaic of exons shared with different proteins
Q36160311	The LDL receptor: how acid pulls the trigger
Q83841386	The Lebanese allele at the LDLR in normocholesterolemic people merits reconsideration of genotype phenotype correlations in familial hypercholesterolemia
Q78019024	The Lebanese mutation as an important cause of familial hypercholesterolemia in Brazil
Q34448076	The SRP9/14 subunit of the signal recognition particle (SRP) is present in more than 20-fold excess over SRP in primate cells and exists primarily free but also in complex with small cytoplasmic Alu RNAs
Q34747495	The UMD-LDLR database: additions to the software and 490 new entries to the database.
Q28292114	The VLDL receptor: an LDL receptor relative with eight ligand binding repeats, LR8
Q28291929	The Very Low Density Lipoprotein Receptor Mediates the Cellular Catabolism of Lipoprotein Lipase and Urokinase-Plasminogen Activator Inhibitor Type I Complexes
Q47840691	The activity of HMG-CoA reductase and acetyl-CoA carboxylase in human apocrine sweat glands, sebaceous glands, and hair follicles is regulated by phosphorylation and by exogenous cholesterol
Q40639637	The adaptor protein beta-arrestin2 enhances endocytosis of the low density lipoprotein receptor
Q40390784	The alpha 2-macroglobulin receptor and epithelial glycoprotein-330: two giant receptors mediating endocytosis of multiple ligands
Q95802452	The alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein and the receptor-associated protein. An overview
Q73417776	The atherogenic lipoprotein phenotype is not caused by a mutation in the coding region of the low density lipoprotein receptor gene
Q37398894	The avian beta-adrenergic receptor: primary structure and membrane topology
Q40675779	The binding ability analysis of the normal VLDL receptor and its mutant
Q35816823	The binding of human low-density lipoproteins to the surface of schistosomula of Schistosoma mansoni is inhibited by polyanions and reduces the binding of anti-schistosomal antibodies
Q78177602	The carboxyl-terminal domain of receptor-associated protein facilitates proper folding and trafficking of the very low density lipoprotein receptor by interaction with the three amino-terminal ligand-binding repeats of the receptor
Q39970114	The citrus flavonoids hesperetin and nobiletin differentially regulate low density lipoprotein receptor gene transcription in HepG2 liver cells
Q28115354	The closed conformation of the LDL receptor is destabilized by the low Ca(++) concentration but favored by the high Mg(++) concentration in the endosome
Q33881217	The complete sequence and structural analysis of human apolipoprotein B-100: relationship between apoB-100 and apoB-48 forms.
Q34620069	The complete sequence of perlecan, a basement membrane heparan sulfate proteoglycan, reveals extensive similarity with laminin A chain, low density lipoprotein-receptor, and the neural cell adhesion molecule
Q33654311	The critical role of mRNA destabilizing protein heterogeneous nuclear ribonucleoprotein d in 3' untranslated region-mediated decay of low-density lipoprotein receptor mRNA in liver tissue.
Q38073929	The curation of genetic variants: difficulties and possible solutions
Q33885414	The cytoplasmic domain is not involved in directing Class 5 mutant LDL receptors to lysosomal degradation
Q30442254	The cytoplasmic domain of P-selectin contains a sorting determinant that mediates rapid degradation in lysosomes
Q48022387	The decrease of liver LDL receptor mRNA during fasting is related to the decrease in serum T3.
Q36320640	The distribution and characteristics of LDL receptor mutations in China: A systematic review
Q77380919	The distribution of circulating receptors on COS 7 cells
Q38336827	The dysfunctional LDL receptor in a monensin-resistant mutant of Chinese hamster ovary cells lacks selected O-linked oligosaccharides
Q93501371	The effect of low density lipoproteins, cholesterol, and 25-hydroxycholesterol on apolipoprotein B gene expression in HepG2 cells
Q71866331	The effects of inbreeding on DNA profile frequency estimates using PCR-based loci
Q42749068	The epidermal growth factor homology domain of the LDL receptor drives lipoprotein release through an allosteric mechanism involving H190, H562, and H586.
Q38717124	The evolution of egg yolk proteins
Q35604030	The familial hypercholesterolemia (FH)-North Karelia mutation of the low density lipoprotein receptor gene deletes seven nucleotides of exon 6 and is a common cause of FH in Finland
Q43591687	The first epidermal growth factor-like domain of the low-density lipoprotein receptor contains a noncanonical calcium binding site
Q36925157	The genetic basis of familial hypercholesterolemia: inheritance, linkage, and mutations.
Q47398986	The globulin seed storage proteins of flowering plants are derived from two ancestral genes
Q41475128	The helical hydrophobic moment avoids prolines in phospholipid-binding proteins
Q24323959	The human class I alcohol dehydrogenase gene cluster: three genes are tandemly organized in an 80-kb-long segment of the genome
Q68182906	The human insulin receptor cDNA: a new tool to study the function of this receptor
Q28615445	The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling
Q39590486	The human interleukin-2 receptor: analysis of structure and function
Q38296407	The hypocholesterolemic agent LY295427 reverses suppression of sterol regulatory element-binding protein processing mediated by oxysterols
Q38335870	The important role for betaVLDLs binding at the fourth cysteine of first ligand-binding domain in the low-density lipoprotein receptor
Q38270837	The insulin receptor: structure and function
Q33930204	The internalization of nerve growth factor by high-affinity receptors on pheochromocytoma PC12 cells.
Q38360019	The life cycle of the low-density lipoprotein receptor: insights from cellular and in-vivo studies
Q38630175	The low density lipoprotein receptor
Q38334866	The low density lipoprotein receptor in Xenopus laevis. I. Five domains that resemble the human receptor
Q38692065	The low density lipoprotein receptor: structure, function and pharmacological modulation
Q47387240	The lowering of plasma lipids following a weight reduction program is related to increased expression of the LDL receptor and lipoprotein lipase
Q35116452	The membrane-bound transcription factor CREB3L1 is activated in response to virus infection to inhibit proliferation of virus-infected cells.
Q39338576	The mode of action of nerve growth factor in PC12 cells
Q38737709	The molecular biology and biochemistry of tissue factor
Q70323689	The multiple origins of human Alu sequences
Q42812960	The neu oncogene encodes an epidermal growth factor receptor-related protein
Q37422654	The novel anticancer agent JNJ-26854165 induces cell death through inhibition of cholesterol transport and degradation of ABCA1
Q24555793	The nucleotide sequence of the human int-1 mammary oncogene; evolutionary conservation of coding and non-coding sequences
Q24679229	The oligodendrocyte-myelin glycoprotein belongs to a distinct family of proteins and contains the HNK-1 carbohydrate
Q30244116	The panorama of familial hypercholesterolemia in Latin America: a systematic review
Q70163348	The physical map of chromosome arm 19q: some new assignments, confirmations and re-assessments
Q41872916	The pore-forming protein (perforin) of cytolytic T lymphocytes is immunologically related to the components of membrane attack complex of complement through cysteine-rich domains
Q35218996	The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase
Q24322953	The primary structures of four subunits of the human, high-molecular-weight proteinase, macropain (proteasome), are distinct but homologous
Q39836508	The receptor model for transport of cholesterol in plasma
Q40370626	The regulation of stearoyl-CoA desaturase (SCD).
Q49847466	The relaxin receptor as a therapeutic target - perspectives from evolution and drug targeting
Q30482054	The repertoire of G protein-coupled receptors in the sea squirt Ciona intestinalis.
Q40594748	The role of a conserved acidic residue in calcium-dependent protein folding for a low density lipoprotein (LDL)-A module: implications in structure and function for the LDL receptor superfamily
Q37357958	The role of calcium in lipoprotein release by the low-density lipoprotein receptor
Q39124393	The role of registries and genetic databases in familial hypercholesterolemia
Q24555815	The sequence and topology of human complement component C9
Q36097802	The structure of HSAG-1, a middle repetitive genetic element which elicits a leukemia-related cellular surface antigen
Q28304137	The sucrase-isomaltase complex: primary structure, membrane-orientation, and evolution of a stalked, intrinsic brush border protein
Q39470753	The use of recombinant DNA techniques for the diagnosis of familial hypercholesterolaemia
Q35180870	The very low density lipoprotein (VLDL) receptor--a peripheral lipoprotein receptor for remnant lipoproteins into fatty acid active tissues.
Q83230328	The very low density lipoprotein receptor A second lipoprotein receptor that may mediate uptake of fatty acids into muscle and fat cells
Q28281141	The very low-density lipoprotein (VLDL) receptor: characterization and functions as a peripheral lipoprotein receptor
Q40665444	The yeast Vps10p cytoplasmic tail mediates lysosomal sorting in mammalian cells and interacts with human GGAs.
Q24595190	The yeast alpha-factor receptor: structural properties deduced from the sequence of the STE2 gene
Q40767999	Therapeutic strategies for familial hypercholesterolemia based on somatic gene transfer.
Q70821098	Three novel mutations in the EGF precursor homology domain of the low-density lipoprotein receptor gene in Northern Irish patients with familial hypercholesterolemia
Q41270687	Three novel partial deletions of the low-density lipoprotein (LDL) receptor gene in familial hypercholesterolemia
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P356	DOI	10.1016/0092-8674(84)90188-0
P698	PubMed publication ID	6091915

P50	author	Joseph L. Goldstein	Q271424
		David W. Russell	Q37382061
P2093	author name string	T Yamamoto
		M S Brown
		W J Schneider
		C G Davis
		M L Casey
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P4510	describes a project that uses	SV-589	Q54970925
P433	issue	1
P407	language of work or name	English	Q1860
P921	main subject	Low density lipoprotein receptor	Q425649
		cell line	Q21014462
P304	page(s)	27-38
P577	publication date	1984-11-01
P1433	published in	Cell	Q655814
P1476	title	The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA
P478	volume	39

The human LDL receptor: a cysteine-rich protein with multiple Alu sequences in its mRNA

scientific article

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