Efficient expression of retroviral vector-transduced human low density lipoprotein (LDL) receptor in LDL receptor-deficient rabbit fibroblasts in vitro

scientific article

Efficient expression of retroviral vector-transduced human low density lipoprotein (LDL) receptor in LDL receptor-deficient rabbit fibroblasts in vitro is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode1988PNAS...85.6538M
P356DOI10.1073/PNAS.85.17.6538
P932PMC publication ID282008
P698PubMed publication ID2842777
P5875ResearchGate publication ID20313024

P2093author name stringJ L Witztum
D Steinberg
T Friedmann
A Miyanohara
M F Sharkey
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Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoterQ29614259
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Deletion in cysteine-rich region of LDL receptor impedes transport to cell surface in WHHL rabbitQ34162054
Overexpression of low density lipoprotein (LDL) receptor eliminates LDL from plasma in transgenic miceQ34175241
Expression of retrovirally transduced genes in primary cultures of adult rat hepatocytesQ34624071
Esterification of low density lipoprotein cholesterol in human fibroblasts and its absence in homozygous familial hypercholesterolemiaQ35114794
Visualization of lipoprotein receptors by ligand blottingQ36597267
Generation of helper-free amphotropic retroviruses that transduce a dominant-acting, methotrexate-resistant dihydrofolate reductase geneQ36886039
Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus productionQ36918698
A novel method for generating region-specific monoclonal antibodies to modified proteins. Application to the identification of human glucosylated low density lipoproteinsQ36991935
Serial inbreeding of rabbits with hereditary hyperlipidemia (WHHL-rabbit).Q39366548
Receptor-mediated endocytosis: concepts emerging from the LDL receptor systemQ39461911
Transformation of mammalian cells by avian myelocytomatosis virus and avian erythroblastosis virusQ40271272
Lineage-specific expression of a human beta-globin gene in murine bone marrow transplant recipients reconstituted with retrovirus-transduced stem cellsQ41904037
Towards gene therapy for hemophilia B.Q45888788
Nonenzymatic glucosylation of low-density lipoprotein alters its biologic activityQ46871536
Monoclonal antibodies to the low density lipoprotein receptor as probes for study of receptor-mediated endocytosis and the genetics of familial hypercholesterolemiaQ52831888
Binding and degradation of low density lipoproteins by cultured human fibroblasts. Comparison of cells from a normal subject and from a patient with homozygous familial hypercholesterolemia.Q54261784
Cholesterol synthesis in vivo and in vitro in the WHHL rabbit, an animal with defective low density lipoprotein receptorsQ67296202
Replacement of liver function in rats by transplantation of microcarrier-attached hepatocytesQ68969871
Expression of an exogenous growth hormone gene by transplantable human epidermal cellsQ69249459
Demonstration of functional low-density lipoprotein receptors by protein blotting in fibroblasts from a subject with homozygous receptor-negative familial hypercholesterolemiaQ70090447
Receptor-dependent and receptor-independent degradation of low density lipoprotein in normal rabbits and in receptor-deficient mutant rabbitsQ72932808
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectlipoproteinQ28350
P304page(s)6538-6542
P577publication date1988-09-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleEfficient expression of retroviral vector-transduced human low density lipoprotein (LDL) receptor in LDL receptor-deficient rabbit fibroblasts in vitro
P478volume85

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