| scholarly article | Q13442814 |
| P50 | author | Richard Flavell | Q2149481 |
| F. Susan Wong | Q63411298 | ||
| P2093 | author name string | E A Green | |
| C Mora | |||
| K Eshima | |||
| P2860 | cites work | Signalling through CD30 protects against autoimmune diabetes mediated by CD8 T cells | Q22009150 |
| CD40 AND CD154 IN CELL-MEDIATED IMMUNITY | Q22255634 | ||
| Reduction of atherosclerosis in mice by inhibition of CD40 signalling | Q24316540 | ||
| Both the Lyt-2+ and L3T4+ T cell subsets are required for the transfer of diabetes in nonobese diabetic mice | Q68123525 | ||
| Following a diabetogenic T cell from genesis through pathogenesis | Q70488192 | ||
| Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression | Q71066478 | ||
| The role of CD8+ T cells in the initiation of insulin-dependent diabetes mellitus | Q71420898 | ||
| The role of the T cell costimulator B7-1 in autoimmunity and the induction and maintenance of tolerance to peripheral antigen | Q71680575 | ||
| RIP-beta 2-microglobulin transgene expression restores insulitis, but not diabetes, in beta 2-microglobulin null nonobese diabetic mice | Q71687824 | ||
| Induction of bcl-x by CD40 engagement rescues sIg-induced apoptosis in murine B cells | Q71746802 | ||
| Mice deficient for the CD40 ligand | Q72610555 | ||
| Major histocompatibility complex class I molecules are required for the development of insulitis in non-obese diabetic mice | Q72650469 | ||
| Beta 2-microglobulin-deficient NOD mice do not develop insulitis or diabetes | Q72787287 | ||
| Major histocompatibility complex class I-deficient NOD-B2mnull mice are diabetes and insulitis resistant | Q72787291 | ||
| Apoptosis is the mode of beta-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) mouse | Q73303056 | ||
| Site alpha is crucial for two routes of IFN gamma-induced MHC class I transactivation: the ISRE-mediated route and a novel pathway involving CIITA | Q73398802 | ||
| CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice | Q73900356 | ||
| Activation of the MHC class II transactivator CIITA by interferon-gamma requires cooperative interaction between Stat1 and USF-1 | Q74277987 | ||
| Dendritic cells and macrophages are the first and major producers of TNF-alpha in pancreatic islets in the nonobese diabetic mouse | Q74412161 | ||
| Pancreatic infiltration but not diabetes occurs in the relative absence of MHC class II-restricted CD4 T cells: studies using NOD/CIITA-deficient mice | Q77320572 | ||
| Local expression of TNFalpha in neonatal NOD mice promotes diabetes by enhancing presentation of islet antigens | Q77658430 | ||
| Mice lacking the transcription factor CIITA--a second look | Q77786394 | ||
| Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome) | Q24317711 | ||
| Dendritic cells and the control of immunity | Q27860918 | ||
| Mice lacking MHC class II molecules | Q28588991 | ||
| Functional diversity of helper T lymphocytes | Q29619415 | ||
| CIITA activates the expression of MHC class II genes in mouse T cells | Q33366765 | ||
| CD40 ligand-mediated interactions are involved in the generation of memory CD8(+) cytotoxic T lymphocytes (CTL) but are not required for the maintenance of CTL memory following virus infection | Q33783902 | ||
| Impairment of antigen-specific T-cell priming in mice lacking CD40 ligand | Q34367466 | ||
| Regulation of MHC class II genes: lessons from a disease | Q34389691 | ||
| The nonobese diabetic mouse as a model of autoimmune diabetes: immune dysregulation gets the NOD. | Q34452348 | ||
| CD40 ligand-deficient mice generate a normal primary cytotoxic T-lymphocyte response but a defective humoral response to a viral infection | Q35873254 | ||
| Syngeneic transfer of autoimmune diabetes from diabetic NOD mice to healthy neonates. Requirement for both L3T4+ and Lyt-2+ T cells. | Q36353954 | ||
| CD28-B7 interactions allow the induction of CD8+ cytotoxic T lymphocytes in the absence of exogenous help. | Q36361861 | ||
| In vivo CD40-gp39 interactions are essential for thymus-dependent humoral immunity. II. Prolonged suppression of the humoral immune response by an antibody to the ligand for CD40, gp39. | Q36362552 | ||
| Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process | Q36363681 | ||
| CD8 T cell clones from young nonobese diabetic (NOD) islets can transfer rapid onset of diabetes in NOD mice in the absence of CD4 cells. | Q36366075 | ||
| CD40-CD40 ligand interactions are critical in T-B cooperation but not for other anti-viral CD4+ T cell functions | Q36366592 | ||
| Constitutive class I-restricted exogenous presentation of self antigens in vivo | Q36367249 | ||
| Local expression of transgene encoded TNF alpha in islets prevents autoimmune diabetes in nonobese diabetic (NOD) mice by preventing the development of auto-reactive islet-specific T cells | Q36367622 | ||
| Initiation of autoimmune diabetes by developmentally regulated presentation of islet cell antigens in the pancreatic lymph nodes | Q36367942 | ||
| TRANCE, a tumor necrosis factor family member critical for CD40 ligand-independent T helper cell activation | Q36368029 | ||
| Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling | Q36377176 | ||
| Viral and bacterial infections interfere with peripheral tolerance induction and activate CD8+ T cells to cause immunopathology | Q36400410 | ||
| Major histocompatibility complex class I-restricted cross-presentation is biased towards high dose antigens and those released during cellular destruction | Q36401408 | ||
| Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1. | Q37683001 | ||
| Genes encoding tumor necrosis factor alpha and granzyme A are expressed during development of autoimmune diabetes. | Q37721023 | ||
| Induction of MHC class I expression by the MHC class II transactivator CIITA. | Q41112935 | ||
| Activation of human dendritic cells through CD40 cross-linking. | Q41440958 | ||
| Immunotherapy of the nonobese diabetic mouse: treatment with an antibody to T-helper lymphocytes | Q41789085 | ||
| CD40L-deficient mice show deficits in antiviral immunity and have an impaired memory CD8+ CTL response. | Q41898717 | ||
| Class II transactivator regulates the expression of multiple genes involved in antigen presentation | Q41944761 | ||
| Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes. | Q42123661 | ||
| Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes | Q46512140 | ||
| T-cell help for cytotoxic T lymphocytes is mediated by CD40-CD40L interactions | Q47982736 | ||
| Help for cytotoxic-T-cell responses is mediated by CD40 signalling | Q47982749 | ||
| A conditioned dendritic cell can be a temporal bridge between a CD4+ T-helper and a T-killer cell | Q47982760 | ||
| Requirement for CD40 ligand in costimulation induction, T cell activation, and experimental allergic encephalomyelitis. | Q48913563 | ||
| Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice. | Q52481758 | ||
| B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice. | Q54120741 | ||
| Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. | Q55066037 | ||
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 225-238 | |
| P577 | publication date | 2000-01-01 | |
| P1433 | published in | Journal of Experimental Medicine | Q3186912 |
| P1476 | title | Neonatal tumor necrosis factor alpha promotes diabetes in nonobese diabetic mice by CD154-independent antigen presentation to CD8(+) T cells | |
| P478 | volume | 191 |
| Q34768674 | Autoreactive CD8 T cells in organ-specific autoimmunity: emerging targets for therapeutic intervention. |
| Q37995319 | B cells as effectors and regulators of autoimmunity |
| Q35318823 | CD154 is a negative regulator of autoaggressive CD8+ T cells in type 1 diabetes |
| Q38288576 | CD154-dependent priming of diabetogenic CD4(+) T cells dissociated from activation of antigen-presenting cells |
| Q44132086 | CD8(+) T cells specific for beta cells encounter their cognate antigens in the islets of NOD mice. |
| Q33928441 | CD8(+) but not CD8(-) dendritic cells cross-prime cytotoxic T cells in vivo. |
| Q37358997 | CD8+ T cells in type 1 diabetes |
| Q36919720 | Co-stimulatory and Co-inhibitory Pathways in Autoimmunity. |
| Q36485931 | Coinhibitory T-cell signaling in islet allograft rejection and tolerance |
| Q35072094 | Contrasting alloreactive CD4+ and CD8+ T cells: there's more to it than MHC restriction |
| Q40051110 | Costimulation controls diabetes by altering the balance of pathogenic and regulatory T cells. |
| Q34715503 | Cytokine and immunosuppressive therapies of type 1 diabetes mellitus |
| Q90413209 | Cytokines in type 1 diabetes: mechanisms of action and immunotherapeutic targets |
| Q74590836 | Defective CD4T cell priming and resistance to experimental autoimmune encephalomyelitis in TNF-deficient mice due to innate immune hypo-responsiveness |
| Q34207623 | Dendritic cells resurrect antigens from dead cells. |
| Q35571875 | Dissecting autoimmune diabetes through genetic manipulation of non-obese diabetic mice |
| Q35539020 | Effector lymphocytes in islet cell autoimmunity |
| Q30310327 | Genetic dissection of the cellular pathways and signaling mechanisms in modeled tumor necrosis factor-induced Crohn's-like inflammatory bowel disease |
| Q37446165 | IFN-γ receptor deficiency prevents diabetes induction by diabetogenic CD4+, but not CD8+, T cells |
| Q35934678 | IP-10 and type 1 diabetes: a question of time and location. |
| Q40093430 | In vivo splenic CD11c cells downregulate CD4 T-cell response thereby decreasing systemic immunity to gene-modified tumour cell vaccine. |
| Q44061029 | Inducible, reversible hair loss in transgenic mice |
| Q79294101 | Insulin-Like Growth Factor (IGF)-I/IGF-Binding Protein-3 Complex: Therapeutic Efficacy and Mechanism of Protection against Type 1 Diabetes |
| Q39272758 | Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity |
| Q35942439 | Manipulating the type 1 vs type 2 balance in type 1 diabetes |
| Q44189001 | Modulation of insulitis and type 1 diabetes by transgenic HLA-DR3 and DQ8 in NOD mice lacking endogenous MHC class II. |
| Q77704341 | Pancreatic lymph node-derived CD4(+)CD25(+) Treg cells: highly potent regulators of diabetes that require TRANCE-RANK signals |
| Q46582446 | Protective role for cytosolic phospholipase A2alpha in autoimmune diabetes of mice |
| Q36121743 | TNF-alpha is critical for antitumor but not antiviral T cell immunity in mice |
| Q46268500 | TSG-6 protein expression in the pancreatic islets of NOD mice. |
| Q73867591 | The temporal importance of TNFalpha expression in the development of diabetes |
| Q44028376 | Timing of pentoxifylline treatment determines its protective effect on diabetes development in the Bio Breeding rat. |
| Q35037402 | Transgenic animal models for type 1 diabetes: linking a tetracycline-inducible promoter with a virus-inducible mouse model. |
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