scholarly article | Q13442814 |
P2093 | author name string | David J Chen | |
John R McCarrey | |||
C Alex McMahan | |||
Christi A Walter | |||
Damon C Herbert | |||
Robert Reddick | |||
Jessica Huamani | |||
Mark I MacInnes | |||
P2860 | cites work | Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination | Q24311337 |
Identification of redox/repair protein Ref-1 as a potent activator of p53 | Q24316161 | ||
Redox activation of Fos-Jun DNA binding activity is mediated by a DNA repair enzyme | Q24555669 | ||
Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation | Q24642901 | ||
An alternative splicing event which occurs in mouse pachytene spermatocytes generates a form of DNA ligase III with distinct biochemical properties that may function in meiotic recombination | Q24647280 | ||
Parent-of-origin effects in multiple endocrine neoplasia type 2B | Q24672503 | ||
Prevalence and parental origin of de novo RET mutations in multiple endocrine neoplasia type 2A and familial medullary thyroid carcinoma. Le Groupe d'Etude des Tumeurs a Calcitonine | Q24680144 | ||
Suppression of spontaneous mutagenesis in human cells by DNA base excision-repair | Q28142064 | ||
The origins, patterns and implications of human spontaneous mutation | Q28206110 | ||
Rate of depurination of native deoxyribonucleic acid | Q28243811 | ||
Mutagenesis by apurinic/apyrimidinic sites | Q28300337 | ||
A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity. | Q52182528 | ||
Morphological analysis of germ cell apoptosis during postnatal testis development in normal and Hsp 70-2 knockout mice. | Q52197889 | ||
Difference in the expression level of DNA polymerase beta among mouse tissues: high expression in the pachytene spermatocyte. | Q52247063 | ||
Spontaneous mutation in man | Q67508556 | ||
Migration of gonocytes into the mammalian gonad and their differentiation | Q68757969 | ||
Kinetics of gametogenesis. I. Comparative histological and autoradiographic studies of oocytes and transitional prospermatogonia during oogenesis and prespermatogenesis | Q68857006 | ||
Identification of transgenic mice carrying the CAT gene with PCR amplification | Q69455485 | ||
Expression of p53 protein in spermatogenesis is confined to the tetraploid pachytene primary spermatocytes | Q70738624 | ||
Expression of the DNA repair gene XRCC1 in baboon tissues | Q70793932 | ||
Xrcc-1 expression during male meiosis in the mouse | Q71666068 | ||
Purification, culture, and fractionation of spermatogenic cells | Q72583949 | ||
Effect of aging on spontaneous and induced mouse testicular germ cell apoptosis | Q74607364 | ||
The mutation rate of the gene for haemophilia, and its segregation ratios in males and females | Q83229412 | ||
Testicular germ cell apoptosis in Bcl6-deficient mice | Q28509583 | ||
Highly efficient base excision repair (BER) in human and rat male germ cells | Q28580367 | ||
Repair of oxidative damage to DNA: enzymology and biology | Q29618065 | ||
Spermatogenic cells of the prepuberal mouse. Isolation and morphological characterization | Q29619534 | ||
Heterozygosity for the mouse Apex gene results in phenotypes associated with oxidative stress. | Q33182233 | ||
Endogenous apurinic/apyrimidinic sites in genomic DNA of mammalian tissues | Q33864452 | ||
An early and massive wave of germinal cell apoptosis is required for the development of functional spermatogenesis | Q33886497 | ||
Germ cell suicide: new insights into apoptosis during spermatogenesis | Q33910562 | ||
Base excision repair in yeast and mammals | Q33984258 | ||
Going APE over ref-1. | Q34053099 | ||
DNA repair/pro-apoptotic dual-role proteins in five major DNA repair pathways: fail-safe protection against carcinogenesis | Q34132208 | ||
Cellular responses to DNA damage | Q34192725 | ||
Base excision repair is limited by different proteins in male germ cell nuclear extracts prepared from young and old mice | Q34276065 | ||
Base excision repair in a network of defence and tolerance | Q34283911 | ||
Exclusive paternal origin of new mutations in Apert syndrome | Q34385938 | ||
The major human abasic endonuclease: formation, consequences and repair of abasic lesions in DNA. | Q34390593 | ||
The occurrence of new mutants in the X-linked recessive Lesch-Nyhan disease | Q34532438 | ||
The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains | Q34878594 | ||
Characterization of mutations induced by ethylnitrosourea in seminiferous tubule germ cells of transgenic B6C3F1 mice | Q35582963 | ||
Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice | Q35919383 | ||
Mutation frequency declines during spermatogenesis in young mice but increases in old mice | Q36283159 | ||
Spectra of spontaneous and mutagen-induced mutations in the lacI gene in transgenic mice | Q37592150 | ||
Infidelity of DNA synthesis associated with bypass of apurinic sites | Q37601868 | ||
Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding | Q38316481 | ||
Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo. | Q38319417 | ||
Identification and characterization of Ref-1, a nuclear protein that facilitates AP-1 DNA-binding activity | Q38330722 | ||
Study design and sample sizes for a lacI transgenic mouse mutation assay | Q38464863 | ||
Mixed spermatogenic germ cell nuclear extracts exhibit high base excision repair activity | Q38660638 | ||
Cellular role of yeast Apn1 apurinic endonuclease/3'-diesterase: repair of oxidative and alkylation DNA damage and control of spontaneous mutation | Q40640344 | ||
Testis and somatic Xrcc-1 DNA repair gene expression | Q41013512 | ||
DNA polymerase-beta and poly(ADP)ribose polymerase mRNAs are differentially expressed during the development of male germinal cells | Q44834025 | ||
Evidence that the mechanism of prenatal germ cell death in the mouse is apoptosis | Q46425526 | ||
Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair. | Q47197545 | ||
The Big Blue(R) transgenic mouse mutation detection assay: the mutation pattern of sectored mutant plaques | Q47605363 | ||
Spontaneous mutations in the Big Blue transgenic system are primarily mouse derived | Q47607298 | ||
The rate of spontaneous mutation of a human gene. 1935. | Q48636282 | ||
On the origin of spontaneous somatic mutations and sectored plaques detected in transgenic mice. | Q50530799 | ||
Towards validation of the Big Blue transgenic mouse mutagenesis assay: the mutational spectrum of ex vivo pinpoint mutant plaques. | Q50534022 | ||
The genetic analysis of lacI mutations in sectored plaques from Big Blue transgenic mice. | Q50753668 | ||
p53-mediated germ cell quality control in spermatogenesis. | Q52181513 | ||
P433 | issue | 18 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | heterozygosity | Q124059385 |
P304 | page(s) | 8145-8153 | |
P577 | publication date | 2004-09-01 | |
P1433 | published in | Molecular and Cellular Biology | Q3319478 |
P1476 | title | Spontaneous mutagenesis is enhanced in Apex heterozygous mice | |
P478 | volume | 24 |
Q54586051 | A case of 14q11.2 microdeletion with autistic features, severe obesity and facial dysmorphisms suggestive of Wolf-Hirschhorn syndrome. |
Q36081999 | Age-related instability in spermatogenic cell nuclear and mitochondrial DNA obtained from Apex1 heterozygous mice |
Q34364004 | BAX and tumor suppressor TRP53 are important in regulating mutagenesis in spermatogenic cells in mice |
Q27025537 | Base excision repair and cancer |
Q34586254 | Base excision repair capacity in informing healthspan |
Q36853499 | Base excision repair, aging and health span. |
Q36241549 | DNA Repair and Cancer Therapy: Targeting APE1/Ref-1 Using Dietary Agents |
Q39211298 | Decrease in abundance of apurinic/apyrimidinic endonuclease causes failure of base excision repair in culture-adapted human embryonic stem cells. |
Q36828516 | Differential expression of hepatic apurinic/apyrimidinic endonuclease 1, a DNA repair enzyme, in chronic hepatitis |
Q52975832 | Dynamic Variations in Genetic Integrity Accompany Changes in Cell Fate. |
Q37455875 | Embryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity. |
Q34311964 | Enhanced genetic integrity in mouse germ cells |
Q33258826 | Evidence for diversity in transcriptional profiles of single hematopoietic stem cells |
Q36326761 | Folate and colorectal cancer in rodents: a model of DNA repair deficiency |
Q37939634 | Haploinsufficiency in mouse models of DNA repair deficiency: modifiers of penetrance |
Q34517201 | Highly mutagenic exocyclic DNA adducts are substrates for the human nucleotide incision repair pathway |
Q37512952 | Human apurinic/apyrimidinic endonuclease 1. |
Q34904605 | Identification and quantification of DNA repair protein apurinic/apyrimidinic endonuclease 1 (APE1) in human cells by liquid chromatography/isotope-dilution tandem mass spectrometry |
Q36011837 | Increased human AP endonuclease 1 level confers protection against the paternal age effect in mice |
Q42557573 | Ionizing radiation-induced mutant frequencies increase transiently in male germ cells of older mice |
Q55664832 | Mitochondrial DNA Integrity Is Maintained by APE1 in Carcinogen-Induced Colorectal Cancer. |
Q37185383 | Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice |
Q37179525 | Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice. |
Q26992194 | Pathways for repairing and tolerating the spectrum of oxidative DNA lesions |
Q36955832 | Production, Purification, and Characterization of ¹⁵N-Labeled DNA Repair Proteins as Internal Standards for Mass Spectrometric Measurements. |
Q36891621 | Recovery of a low mutant frequency after ionizing radiation-induced mutagenesis during spermatogenesis |
Q28386202 | Role of oxidative DNA damage in mitochondrial dysfunction and Huntington's disease pathogenesis |
Q36694479 | S-adenosylmethionine regulates apurinic/apyrimidinic endonuclease 1 stability: implication in hepatocarcinogenesis |
Q38925522 | The prion protein is critical for DNA repair and cell survival after genotoxic stress |
Q38717164 | Tumor-associated APE1 variant exhibits reduced complementation efficiency but does not promote cancer cell phenotypes |
Q35672223 | Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability |
Q34983433 | Uracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cells |
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