scholarly article | Q13442814 |
P356 | DOI | 10.1074/JBC.M313983200 |
P698 | PubMed publication ID | 14973123 |
P50 | author | Lisiane B Meira | Q56432067 |
P2093 | author name string | Jun Nakamura | |
Errol C Friedberg | |||
Ahmad R Heydari | |||
Diane C Cabelof | |||
Julian J Raffoul | |||
P2860 | cites work | Interaction of human apurinic endonuclease and DNA polymerase beta in the base excision repair pathway | Q24313920 |
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XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions | Q24535921 | ||
A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress | Q40231225 | ||
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Oxidative stress associated DNA damage in testis of mice: induction of abnormal sperms and effects on fertility | Q43806323 | ||
Induction of DNA polymerase beta-dependent base excision repair in response to oxidative stress in vivo | Q44110036 | ||
Drosophila S3 ribosomal protein accelerates repair of 8-oxoguanine performed by human and mouse cell extracts | Q44521596 | ||
Comparative analysis of the ability of precursor germ cells and epididymal spermatozoa to generate reactive oxygen metabolites. | Q46593635 | ||
Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps | Q47724136 | ||
A murine AP-endonuclease gene-targeted deficiency with post-implantation embryonic progression and ionizing radiation sensitivity. | Q52182528 | ||
Reduction of oxidation during the preparation of DNA and analysis of 8-hydroxy-2'-deoxyguanosine. | Q52237775 | ||
Quantitative analysis of gene-specific DNA damage in human spermatozoa. | Q53919370 | ||
A mouse DNA repair enzyme (APEX nuclease) having exonuclease and apurinic/apyrimidinic endonuclease activities: purification and characterization | Q54693226 | ||
Lipid Peroxidation and the Reactions of Superoxide and Hydrogen Peroxide in Mouse Spermatozoa | Q70217313 | ||
Carboplatin treatment induces dose-dependent increases in the frequency of micronuclei in Ehrlich ascites tumor cells | Q71631641 | ||
Database of mouse strains carrying targeted mutations in genes affecting biological responses to DNA damage. Version 5 | Q73314976 | ||
Passing the baton in base excision repair | Q73505096 | ||
Genetic interaction between HAP1/REF-1 and p53 | Q73777265 | ||
AP endonuclease 1 has no biologically significant 3(')-->5(')-exonuclease activity | Q78654167 | ||
Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects inE.coli xth(exonuclease III) mutants | Q24629413 | ||
p53, the cellular gatekeeper for growth and division | Q27860990 | ||
Yeast structural gene (APN1) for the major apurinic endonuclease: homology to Escherichia coli endonuclease IV | Q27930192 | ||
Substrate specificity of human endonuclease III (hNTH1). Effect of human APE1 on hNTH1 activity | Q28202324 | ||
Role of XRCC1 in the coordination and stimulation of oxidative DNA damage repair initiated by the DNA glycosylase hOGG1 | Q28203088 | ||
DNA polymerase beta is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts | Q28365541 | ||
Highly efficient base excision repair (BER) in human and rat male germ cells | Q28580367 | ||
Mechanisms of human DNA repair: an update | Q28608973 | ||
Incision Activity of Human Apurinic Endonuclease (Ape) at Abasic Site Analogs in DNA | Q28609201 | ||
Stimulation of human 8-oxoguanine-DNA glycosylase by AP-endonuclease: potential coordination of the initial steps in base excision repair | Q28645611 | ||
Completion of base excision repair by mammalian DNA ligases | Q28645625 | ||
A quantitative model of human DNA base excision repair. I. Mechanistic insights | Q28646701 | ||
Functional characterization of Ape1 variants identified in the human population | Q33786876 | ||
Going APE over ref-1. | Q34053099 | ||
Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline | Q34172771 | ||
Mechanism of stimulation of the DNA glycosylase activity of hOGG1 by the major human AP endonuclease: bypass of the AP lyase activity step | Q34286685 | ||
The stalling of transcription at abasic sites is highly mutagenic | Q34463060 | ||
p53 regulation of DNA excision repair pathways | Q34552957 | ||
A role for p53 in base excision repair. | Q34582602 | ||
Polymorphisms in DNA repair and environmental interactions | Q34994597 | ||
Cysteine 64 of Ref-1 is not essential for redox regulation of AP-1 DNA binding | Q35019872 | ||
Dynamics and diversions in base excision DNA repair of oxidized abasic lesions | Q35026374 | ||
DNA damage and repair | Q35050625 | ||
Repair mechanisms for oxidative DNA damage | Q35109446 | ||
Challenges and complexities in estimating both the functional impact and the disease risk associated with the extensive genetic variation in human DNA repair genes | Q35114513 | ||
Biochemical entities involved in reactive oxygen species generation by human spermatozoa. | Q35136630 | ||
Mammalian DNA base excision repair proteins: their interactions and role in repair of oxidative DNA damage | Q35576447 | ||
Attenuation of DNA polymerase beta-dependent base excision repair and increased DMS-induced mutagenicity in aged mice | Q35919383 | ||
The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice. | Q37377727 | ||
Infidelity of DNA synthesis associated with bypass of apurinic sites | Q37601868 | ||
Base excision repair intermediates as topoisomerase II poisons | Q38295973 | ||
Ref-1 regulates the transactivation and pro-apoptotic functions of p53 in vivo. | Q38319417 | ||
Mixed spermatogenic germ cell nuclear extracts exhibit high base excision repair activity | Q38660638 | ||
P433 | issue | 18 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | haploinsufficiency | Q852654 |
P304 | page(s) | 18425-18433 | |
P577 | publication date | 2004-02-18 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | Apurinic/apyrimidinic endonuclease (APE/REF-1) haploinsufficient mice display tissue-specific differences in DNA polymerase beta-dependent base excision repair | |
P478 | volume | 279 |
Q54586051 | A case of 14q11.2 microdeletion with autistic features, severe obesity and facial dysmorphisms suggestive of Wolf-Hirschhorn syndrome. |
Q34864938 | A novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase beta |
Q55402216 | APE1 deficiency promotes cellular senescence and premature aging features. |
Q36229211 | APE1- and APE2-dependent DNA breaks in immunoglobulin class switch recombination. |
Q27025537 | Base excision repair and cancer |
Q37325427 | Base excision repair in the mammalian brain: implication for age related neurodegeneration |
Q40177980 | Bcl2 impedes DNA mismatch repair by directly regulating the hMSH2-hMSH6 heterodimeric complex |
Q40300992 | Bcl2 suppresses DNA repair by enhancing c-Myc transcriptional activity |
Q36241549 | DNA Repair and Cancer Therapy: Targeting APE1/Ref-1 Using Dietary Agents |
Q28241953 | Differential expression of APE1 and APE2 in germinal centers promotes error-prone repair and A:T mutations during somatic hypermutation |
Q28822387 | Dioxin induces Ahr-dependent robust DNA demethylation of the Cyp1a1 promoter via Tdg in the mouse liver |
Q37455875 | Embryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity. |
Q34478743 | Folate deficiency regulates expression of DNA polymerase β in response to oxidative stress |
Q33859467 | Functional specialization of Chlamydomonas reinhardtii cytosolic thioredoxin h1 in the response to alkylation-induced DNA damage |
Q33241207 | Genistein inhibits radiation-induced activation of NF-kappaB in prostate cancer cells promoting apoptosis and G2/M cell cycle arrest |
Q44952054 | Imbalanced base excision repair in response to folate deficiency is accelerated by polymerase beta haploinsufficiency |
Q33748270 | Integrated genomics of susceptibility to alkylator-induced leukemia in mice |
Q34764888 | Mechanism and regulation of class switch recombination |
Q37185383 | Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice |
Q34107442 | Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease 1. |
Q26996127 | New perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseases |
Q37179525 | Oxidative stress alters base excision repair pathway and increases apoptotic response in apurinic/apyrimidinic endonuclease 1/redox factor-1 haploinsufficient mice. |
Q28256164 | Sequence-specific cleavage of dsRNA by Mini-III RNase |
Q37493345 | Spontaneous mutagenesis is enhanced in Apex heterozygous mice |
Q46497055 | The hydrophobic hinge region of rat DNA polymerase beta is critical for substrate binding pocket geometry |
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