Studies toward bivalent κ opioids derived from salvinorin A: heteromethylation of the furan ring reduces affinity.

scientific article published on 20 December 2013

Studies toward bivalent κ opioids derived from salvinorin A: heteromethylation of the furan ring reduces affinity. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.3762/BJOC.9.328
P932PMC publication ID3896271
P698PubMed publication ID24454571
P5875ResearchGate publication ID259879353

P50authorThomas A. MunroQ42073508
P2093author name stringWei Xu
Bruce M Cohen
Douglas M Ho
Lee-Yuan Liu-Chen
P2860cites workStructure of the human κ-opioid receptor in complex with JDTicQ24308048
Duration of action of a broad range of selective κ-opioid receptor antagonists is positively correlated with c-Jun N-terminal kinase-1 activationQ24634808
2-Methoxymethyl-salvinorin B is a potent kappa opioid receptor agonist with longer lasting action in vivo than salvinorin AQ24642017
Dynorphin, stress, and depressionQ24650168
Standard protecting groups create potent and selective kappa opioids: salvinorin B alkoxymethyl ethersQ24651427
Crystal structure of the µ-opioid receptor bound to a morphinan antagonistQ27678133
Structure of the nociceptin/orphanin FQ receptor in complex with a peptide mimeticQ27679151
Structure of the δ-opioid receptor bound to naltrindoleQ27679153
International Union of Pharmacology Committee on Receptor Nomenclature and Drug Classification. XXXVIII. Update on terms and symbols in quantitative pharmacologyQ28189543
Neuropharmacology of the naturally occurring kappa-opioid hallucinogen salvinorin AQ30467220
Molecular signatures of G-protein-coupled receptorsQ34327700
Synthesis and in vitro evaluation of salvinorin A analogues: effect of configuration at C(2) and substitution at C(18).Q34538561
Chemotype-selective modes of action of κ-opioid receptor agonistsQ37348899
Salvinorin A and derivatives: protection from metabolism does not prolong short-term, whole-brain residenceQ37349384
The best of both worlds? Bitopic orthosteric/allosteric ligands of g protein-coupled receptorsQ37930665
Class A G-protein-coupled receptor (GPCR) dimers and bivalent ligandsQ38107222
Differential signaling properties at the kappa opioid receptor of 12-epi-salvinorin A and its analoguesQ39421211
Modification of the furan ring of salvinorin A: identification of a selective partial agonist at the kappa opioid receptorQ41872689
Salvinorin B methoxymethyl etherQ42073472
Antinociceptive effects of herkinorin, a MOP receptor agonist derived from salvinorin A in the formalin test in rats: new concepts in mu opioid receptor pharmacology: from a symposium on new concepts in mu-opioid pharmacology.Q42633341
Salvinorin A: allosteric interactions at the mu-opioid receptorQ44332543
Toward a structure-based model of salvinorin A recognition of the kappa-opioid receptorQ44337934
Structure-activity relationships of trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidine antagonists for mu- and kappa-opioid receptorsQ44340510
Synthetic studies of neoclerodane diterpenes from Salvia divinorum: selective modification of the furan ring.Q51808389
Salvinorin B derivatives, EOM-Sal B and MOM-Sal B, produce stimulus generalization in male Sprague-Dawley rats trained to discriminate salvinorin A.Q51858703
Allosteric Modulation of G Protein–Coupled ReceptorsQ56115675
Structure-activity relationships in narcotic antagonists with N-furylmethyl substituentsQ68343293
P304page(s)2916-2924
P577publication date2013-12-20
P1433published inBeilstein Journal of Organic ChemistryQ2894008
P1476titleStudies toward bivalent κ opioids derived from salvinorin A: heteromethylation of the furan ring reduces affinity
P478volume9

Reverse relations

Q34796464Synthesis and κ-opioid receptor activity of furan-substituted salvinorin A analoguescites workP2860

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